Actinic KeratosesNCT05987553
The Influence of an E-learning Program on Recognition of Actinic Keratosis
An observational study of Actinic Keratoses and E-learning, run by Maastricht University Medical Center at 1 site in Netherlands.
Trial summary
The evaluation on the diagnostic accuracy of actinic keratosis recognition by general practitioners before and after participation on an e-learning program. Read more about this study
- Who is it for?
- Ages 18 to 67 years
- Conditions the study is for
- Actinic Keratoses, E-learning, Dermatology
- What is being tested?
- e-learning program
- How many people
- 32 participants
- Where
- 1 siteNetherlands
- Study dates
- 1 Jan 2021to 1 Dec 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 67 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Data from general practitioners who
Who may be able to join
- general practitioner in the Netherlands
- access to e-learning module via phone/computer/tablet
- knowledge of the Dutch language
Who cannot join
- no knowledge of the Dutch language
- different specialists than general practitioner
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Influence of an E-learning Program on Recognition of Actinic Keratosis by General Practitioners). Implementation of Actinic Keratosis Guidelines Among General Practitioners.
The evaluation on the diagnostic accuracy of actinic keratosis recognition by general practitioners before and after participation on an e-learning program.
Read the detailed description
Actinic keratosis is defined as the most frequent common intra-epithelial neoplasm in the Caucasian population, with an increasing prevalence. If left untreated, actinic keratosis has the potency to develop into a cutaneous squamous-cell carcinoma. Treatment of actinic keratosis is aimed at both lesion reduction and to prevent malignant transformation. To achieve treatment adherence for patients, it is necessary to raise physician awareness about actinic keratosis.
This study primarily aimed to investigate whether the sensitivity of establishing a correct actinic keratosis diagnosis by general practitioners (in training) would increase after participating in an e-learning program about the recognition of actinic keratosis. This was achieved by comparing the results of a pre- and post-test completed by general practitioners which was incorporated in the e-learning program.
- Conditions
- Actinic Keratoses, E-learning, Dermatology
- Being tested
- e-learning program
- Medical subject headings
- Keratosis, Actinic
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
e-learning programOther
All participants participate in this intervention: an e-learning program about the recognition of actinic keratosis. The program exists of 30 cases. Each case exists of a question and thorough explanation including references to various sources.
| Study group | Role | What they receive |
|---|---|---|
| General practitioners | All participants were general practitioners (in training). Receives: Other: e-learning program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Difference in sensitivity
Difference in sensitivity of participants in the recognition of actinic keratosis, before and after the use of an e-learning program (paired).
Measured: Measurement by baseline and after finalising the e-learning program (same day up until 30 days)
Difference in specificity
Difference in specificity of participants in the recognition of actinic keratosis, before and after the use of an e-learning program (paired).
Measured: Measurement by baseline and after finalising the e-learning program (same day up until 30 days)
Secondary outcomes (1)
Difference in area under the receiver operating characteristic (ROC) curve
Difference in area under the curve of participants in the recognition of actinic keratosis, before and after the use of an e-learning program.
Measured: Measurement by baseline and after finalising the e-learning program (same day up until 30 days)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Aug 2023
- Study start1 Jan 2021
- Primary completion1 Jan 2024
- Study completion1 Dec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Actinic KeratosesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 32 participants (actual)
Sponsor and investigators
- Lead sponsor
- Maastricht University Medical Center
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Klara Mosterd, prof.dr., Principal investigator, Maastricht UMC
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05987553
- Sponsor's protocol ID
- 2020-1334
- Status last verified
- Apr 2025
- First submitted
- 20 Jul 2023
- Last updated
- 4 Apr 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Influence of an E-learning Program on Recognition of Actinic Keratosis by General Practitioners). Implementation of Actinic Keratosis Guidelines Among General Practitioners.
- ClinicalTrials.gov ID
- NCT05987553
- Acronym / sponsor ID
- 2020-1334
- Conditions
- Actinic Keratoses, E-learning, Dermatology
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 32 participants (actual)
- Lead sponsor
- Maastricht University Medical CenterUniversity, hospital or other
- Study start
- 1 Jan 2021 (actual)
- Primary completion
- 1 Jan 2024 (actual)
- Study completion
- 1 Dec 2025 (estimated)
- First posted
- 14 Aug 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The evaluation on the diagnostic accuracy of actinic keratosis recognition by general practitioners before and after participation on an e-learning program.
Detailed description
Actinic keratosis is defined as the most frequent common intra-epithelial neoplasm in the Caucasian population, with an increasing prevalence. If left untreated, actinic keratosis has the potency to develop into a cutaneous squamous-cell carcinoma. Treatment of actinic keratosis is aimed at both lesion reduction and to prevent malignant transformation. To achieve treatment adherence for patients, it is necessary to raise physician awareness about actinic keratosis.
This study primarily aimed to investigate whether the sensitivity of establishing a correct actinic keratosis diagnosis by general practitioners (in training) would increase after participating in an e-learning program about the recognition of actinic keratosis. This was achieved by comparing the results of a pre- and post-test completed by general practitioners which was incorporated in the e-learning program.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| General practitioners | – | Other: e-learning programAll participants were general practitioners (in training). |
Who may qualify
- Ages
- 18 to 67 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Data from general practitioners who
Key inclusion criteria (3 listed)
- general practitioner in the Netherlands
- access to e-learning module via phone/computer/tablet
- knowledge of the Dutch language
Key exclusion criteria (2 listed)
- no knowledge of the Dutch language
- different specialists than general practitioner
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| e-learning programAll participants participate in this intervention: an e-learning program about the recognition of actinic keratosis. The program exists of 30 cases. Each case exists of a question and thorough explanation including references to various sources. | Other | General practitioners |
Primary outcome
Difference in sensitivity
Time frame: Measurement by baseline and after finalising the e-learning program (same day up until 30 days)
Difference in sensitivity of participants in the recognition of actinic keratosis, before and after the use of an e-learning program (paired).
Difference in specificity
Time frame: Measurement by baseline and after finalising the e-learning program (same day up until 30 days)
Difference in specificity of participants in the recognition of actinic keratosis, before and after the use of an e-learning program (paired).
1 secondary outcome
Difference in area under the receiver operating characteristic (ROC) curve
Time frame: Measurement by baseline and after finalising the e-learning program (same day up until 30 days)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Apr 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Klara Mosterd, prof.dr. principal investigator
Maastricht UMC
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Actinic Keratoses and E-learning, run by Maastricht University Medical Center at 1 site in Netherlands.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 4 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Netherlands. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Difference in sensitivity (time frame: Measurement by baseline and after finalising the e-learning program (same day up until 30 days)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Apr 2025.