Catheter ComplicationsNCT06014099
Research on the Application of Blood Collection Through Midline Catheters of Different Lengths
A study testing Long peripheral venous catheters for blood collection, Midline catheter for blood collection and SPCs for blood collection in people with Catheter Complications, run by Sir Run Run Shaw Hospital at 1 site in China.
Trial summary
Therefore, in this study, the investigators propose to use a randomized controlled prospective open study on inpatients with difficult blood collection, by comparing the effects of the application of two types of peripheral venous catheters for blood collection via LPC and MC, with a view to improving the success rate… Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Catheter Complications
- What is being tested?
- Long peripheral venous catheters for blood collection, Midline catheter for blood collection and SPCs for blood collection
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 162 participants
- Where
- 1 siteChina
- Study dates
- 27 Oct 2023to 30 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Meet the international diagnostic criteria for metabolic syndrome (such as ATP III criteria or domestic Diabetes Branch of Chinese Medical Association criteria).
- The estimated treatment time of intravenous infusion is 1-4 weeks, and the nature of the infusion drug meets the indications of LPCs and MCs.
- Blood samples should be collected more than 3 times during the hospital.
Who cannot join
- A history of radiotherapy, thrombosis, and trauma at the catheter site.
- Plan to discharge from the hospital with the tube.
- Vulnerable groups, including people with mental illness, cognitive impairment, critically ill patients, minors, pregnant women, illiterate, etc.
Trial locations and contacts
1 site in 1 country.
About this study
Therefore, in this study, the investigators propose to use a randomized controlled prospective open study on inpatients with difficult blood collection, by comparing the effects of the application of two types of peripheral venous catheters for blood collection via LPC and MC, with a view to improving the success rate of blood collection in difficult peripheral venous blood collection, and providing a theoretical basis for the later application of long peripheral venous catheters and midline catheters; and providing a basis for optimizing the experience of venous blood collection by nurses.
Read the detailed description
Using block randomization, patients were randomized in 1:1:1 blocks into experimental arm 1(Long peripheral venous catheter), experimental arm 2(midline catheter), and control (short peripheral venous catheter) with a block length of 6. Patients have a total of 27 blocks, import data into SPSS23, randomly group by SPSS, generate random numbers, and group according to the size of random numbers in each unit group, the largest in the group is assigned to the experimental group 1, the middle of the group is assigned to the experimental group 2, and the smallest in the group is assigned to the control group. The experimental group1 used the LPC for blood collection, the experimental group 2 used the MC for blood collection,and the control group used the Short PIVC for blood collection.
- Conditions
- Catheter Complications
- Being tested
- Long peripheral venous catheters for blood collection, Midline catheter for blood collection, SPCs for blood collection
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Long peripheral venous catheters for blood collectionBehavioural
used LPC for blood collection
Midline catheter for blood collectionBehavioural
used MCs for blood collection
SPCs for blood collectionBehavioural
used SPCs for blood collection
| Study group | Role | What they receive |
|---|---|---|
| Midline catheter | Experimental | The test group2 used MC for blood collection. Receives: Behavioral: Midline catheter for blood collection |
| Long peripheral venous catheters | Experimental | In the test 1 group, blood was collected using LPC. Receives: Behavioral: Long peripheral venous catheters for blood collection |
| short peripheral venous catheters | Other | In the control group,blood was collected using SPC. Receives: Behavioral: SPCs for blood collection |
What is being measured
The primary outcome is the main question the study is designed to answer.
Success rate of first blood collection
Number of successful initial venous blood collection cases as a percentage of the total number of cases in this group
Measured: during catheter indwelling,an average of 2 weeks
Total success rate of blood collection
Number of patients with successful intravenous blood collection as a proportion of the number of cases in this group
Measured: during catheter indwelling,an average of 2 weeks
Secondary outcomes (2)
Catheter-related complication rate
The proportion of patients with complications as a proportion of the total number of cases
Measured: during catheter indwelling,an average of 2 weeks
Number of days for catheters to linger
The number of days between catheter insertion and catheter removal
Measured: during catheter indwelling,an average of 2 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Aug 2023
- Study start27 Oct 2023
- Primary completion30 Dec 2025
- Study completion30 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (7)Papers the sponsor has linked to this study.
- Other trials for Catheter ComplicationsStudies of the same condition, open and under way.
- More trials run by Sir Run Run Shaw HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 162 participants (actual)
Sponsor and investigators
- Lead sponsor
- Sir Run Run Shaw Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Zhao Linfang, Sir Run Run Shaw Hospital
- Investigators
- Linfang Zhao, Principal investigator, Sir Run Run Shaw Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06014099
- Sponsor's protocol ID
- IV202308
- Status last verified
- Oct 2023
- First submitted
- 13 Mar 2023
- Last updated
- 23 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Lima-Oliveira G, Lippi G, Salvagno GL, Picheth G, Guidi GC. Laboratory Diagnostics and Quality of Blood Collection. J Med Biochem. 2015 Jul;34(3):288-294. doi: 10.2478/jomb-2014-0043. Epub 2015 Jul 14.
PubMed 28356839HO Guidelines Approved by the Guidelines Review Committee[J]. 2015.
Tsukuda Y, Funakoshi T, Nasuhara Y, Nagano Y, Shimizu C, Iwasaki N. Venipuncture Nerve Injuries in the Upper Extremity From More Than 1 Million Procedures. J Patient Saf. 2019 Dec;15(4):299-301. doi: 10.1097/PTS.0000000000000264.
PubMed 27314202Jeong Y, Park H, Jung MJ, Kim MS, Byun S, Choi Y. Comparisons of laboratory results between two blood samplings: Venipuncture versus peripheral venous catheter-A systematic review with meta-analysis. J Clin Nurs. 2019 Oct;28(19-20):3416-3429. doi: 10.1111/jocn.14918. Epub 2019 Jun 10.
PubMed 31112315Gorski LA, Hadaway L, Hagle ME, Broadhurst D, Clare S, Kleidon T, Meyer BM, Nickel B, Rowley S, Sharpe E, Alexander M. Infusion Therapy Standards of Practice, 8th Edition. J Infus Nurs. 2021 Jan-Feb 01;44(1S Suppl 1):S1-S224. doi: 10.1097/NAN.0000000000000396. No abstract available.
PubMed 33394637Wicker S, Stirn AV, Rabenau HF, von Gierke L, Wutzler S, Stephan C. Needlestick injuries: causes, preventability and psychological impact. Infection. 2014 Jun;42(3):549-52. doi: 10.1007/s15010-014-0598-0. Epub 2014 Feb 14.
PubMed 24526576Zhang Y, Zhang S, Chen J, Zhao R. Blood sampling from peripherally inserted central catheter is effective and safe for patients with head and neck cancers. J Vasc Access. 2021 May;22(3):424-431. doi: 10.1177/1129729820943458. Epub 2020 Aug 3.
PubMed 32741243
Study at a glance
From the registry record, last updated by the sponsor on 23 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Research on the Application of Blood Collection Through Midline Catheters of Different Lengths
- ClinicalTrials.gov ID
- NCT06014099
- Acronym / sponsor ID
- IV202308
- Conditions
- Catheter Complications
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 162 participants (actual)
- Lead sponsor
- Sir Run Run Shaw HospitalUniversity, hospital or other
- Study start
- 27 Oct 2023 (actual)
- Primary completion
- 30 Dec 2025 (actual)
- Study completion
- 30 Dec 2025 (actual)
- First posted
- 28 Aug 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Therefore, in this study, the investigators propose to use a randomized controlled prospective open study on inpatients with difficult blood collection, by comparing the effects of the application of two types of peripheral venous catheters for blood collection via LPC and MC, with a view to improving the success rate of blood collection in difficult peripheral venous blood collection, and providing a theoretical basis for the later application of long peripheral venous catheters and midline catheters; and providing a basis for optimizing the experience of venous blood collection by nurses.
Detailed description
Using block randomization, patients were randomized in 1:1:1 blocks into experimental arm 1(Long peripheral venous catheter), experimental arm 2(midline catheter), and control (short peripheral venous catheter) with a block length of 6. Patients have a total of 27 blocks, import data into SPSS23, randomly group by SPSS, generate random numbers, and group according to the size of random numbers in each unit group, the largest in the group is assigned to the experimental group 1, the middle of the group is assigned to the experimental group 2, and the smallest in the group is assigned to the control group. The experimental group1 used the LPC for blood collection, the experimental group 2 used the MC for blood collection,and the control group used the Short PIVC for blood collection.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Midline catheter | Experimental | Behavioral: Midline catheter for blood collectionThe test group2 used MC for blood collection. |
| Long peripheral venous catheters | Experimental | Behavioral: Long peripheral venous catheters for blood collectionIn the test 1 group, blood was collected using LPC. |
| short peripheral venous catheters | Other | Behavioral: SPCs for blood collectionIn the control group,blood was collected using SPC. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Meet the international diagnostic criteria for metabolic syndrome (such as ATP III criteria or domestic Diabetes Branch of Chinese Medical Association criteria).
- The estimated treatment time of intravenous infusion is 1-4 weeks, and the nature of the infusion drug meets the indications of LPCs and MCs.
- Blood samples should be collected more than 3 times during the hospital.
Key exclusion criteria (3 listed)
- A history of radiotherapy, thrombosis, and trauma at the catheter site.
- Plan to discharge from the hospital with the tube.
- Vulnerable groups, including people with mental illness, cognitive impairment, critically ill patients, minors, pregnant women, illiterate, etc.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Long peripheral venous catheters for blood collectionused LPC for blood collection | Behavioural | Long peripheral venous catheters |
| Midline catheter for blood collectionused MCs for blood collection | Behavioural | Midline catheter |
| SPCs for blood collectionused SPCs for blood collection | Behavioural | short peripheral venous catheters |
Primary outcome
Success rate of first blood collection
Time frame: during catheter indwelling,an average of 2 weeks
Number of successful initial venous blood collection cases as a percentage of the total number of cases in this group
Total success rate of blood collection
Time frame: during catheter indwelling,an average of 2 weeks
Number of patients with successful intravenous blood collection as a proportion of the number of cases in this group
2 secondary outcomes
Catheter-related complication rate
Time frame: during catheter indwelling,an average of 2 weeks
Number of days for catheters to linger
Time frame: during catheter indwelling,an average of 2 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Apr 2026.
- Background: PubMed 28356839Lima-Oliveira G, Lippi G, Salvagno GL, Picheth G, Guidi GC. Laboratory Diagnostics and Quality of Blood Collection. J Med Biochem. 2015 Jul;34(3):288-294. doi: 10.2478/jomb-2014-0043. Epub 2015 Jul 14.
- BackgroundHO Guidelines Approved by the Guidelines Review Committee[J]. 2015.
- Background: PubMed 27314202Tsukuda Y, Funakoshi T, Nasuhara Y, Nagano Y, Shimizu C, Iwasaki N. Venipuncture Nerve Injuries in the Upper Extremity From More Than 1 Million Procedures. J Patient Saf. 2019 Dec;15(4):299-301. doi: 10.1097/PTS.0000000000000264.
- Background: PubMed 31112315Jeong Y, Park H, Jung MJ, Kim MS, Byun S, Choi Y. Comparisons of laboratory results between two blood samplings: Venipuncture versus peripheral venous catheter-A systematic review with meta-analysis. J Clin Nurs. 2019 Oct;28(19-20):3416-3429. doi: 10.1111/jocn.14918. Epub 2019 Jun 10.
- Background: PubMed 33394637Gorski LA, Hadaway L, Hagle ME, Broadhurst D, Clare S, Kleidon T, Meyer BM, Nickel B, Rowley S, Sharpe E, Alexander M. Infusion Therapy Standards of Practice, 8th Edition. J Infus Nurs. 2021 Jan-Feb 01;44(1S Suppl 1):S1-S224. doi: 10.1097/NAN.0000000000000396. No abstract available.
- Background: PubMed 24526576Wicker S, Stirn AV, Rabenau HF, von Gierke L, Wutzler S, Stephan C. Needlestick injuries: causes, preventability and psychological impact. Infection. 2014 Jun;42(3):549-52. doi: 10.1007/s15010-014-0598-0. Epub 2014 Feb 14.
- Background: PubMed 32741243Zhang Y, Zhang S, Chen J, Zhao R. Blood sampling from peripherally inserted central catheter is effective and safe for patients with head and neck cancers. J Vasc Access. 2021 May;22(3):424-431. doi: 10.1177/1129729820943458. Epub 2020 Aug 3.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Linfang Zhao principal investigator
Sir Run Run Shaw Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Long peripheral venous catheters for blood collection, Midline catheter for blood collection and SPCs for blood collection in people with Catheter Complications, run by Sir Run Run Shaw Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Success rate of first blood collection (time frame: during catheter indwelling,an average of 2 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06014099, which also lists 7 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Apr 2026.