Moderate and High Intensity Training and Hemoglobin LevelsNCT06032806
Effects of 8 Weeks Moderate and High Intensity Training on Hemoglobin Levels of Female Students
A study testing moderate intensity and High intensity in people with Moderate and High Intensity Training and Hemoglobin Levels, run by Riphah International University at 1 site in Pakistan.
Trial summary
This study aimed to assess the effectiveness of 8 weeks of moderate and high intensity training on hemoglobin levels of female students Read more about this study
- Who is it for?
- Ages 23 to 27 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Moderate and High Intensity Training and Hemoglobin Levels
- What is being tested?
- moderate intensity and High intensity
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 28 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Aug 2023to 29 Jan 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 23 to 27 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age between 18-25 years.
- Hb levels greater than 10 \& less than 12.0 gm/dl
Who cannot join
- Female staff of the institute.
- Students already engaged in physical activity.
- Hb levels greater than 12.0 \& less than 10 gm/dl
- Female having any bony deformity (spine, hip, knee \& ankle)
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Sargodha institute of health sciences
Sargodha, Punjab Province, 40100
About this study
This study aimed to assess the effectiveness of 8 weeks of moderate and high intensity training on hemoglobin levels of female students
Read the detailed description
Anemia is a global health problem and occurs at all stages of the life cycle but is more prevalent among 50% young females of reproductive age and 21% of age group 9-29 years, faces the same problem in Punjab, a province of Pakistan. Higher percentage was found in hostilities (39.2%) as compared to day scholars (23.1%). Anemia has been shown affect to mental development and learning capacity, stress level, may cause irritability, fatigue, difficulty with concentration, lethargy, weakness, and increased susceptibility to infection. Consequently, anemic patients may tend to be poor in quality of life.
Adult men and adult women have different hemoglobin levels in health. This difference is independent of iron status - iron replete pre-menopausal women have mean hemoglobin levels approximately 12% lower than age \& race matched men. National Health and Nutrition Examination Survey (NHANES HI) showed that 9% to11% of adolescent girls and women of child-bearing age were iron-deficient and 2% to5% of them were diagnosed with iron deficiency anemia. Iron deficiency with the presence of low hemoglobin is the criterion for the diagnosis of iron deficiency anemia.There have been frequent reports of a sub-optimal hematological status being observed in athletes involved in intensive physical activity.
Physical activity especially moderate and high intensity reduce mortality and prevent many chronic diseases such as hypertension, diabetes, stroke, and cancer, and stimulate erythropoiesis, which can promote healthy cognitive and psycho-social function and increased hemoglobin concentration Hb lead to increase maximum oxygen carrying capacity. A study reported that aerobic exercise increased hemoglobin (Hb) concentration and hematologic factors in young females.
Recently, the rising prevalence of physical inactivity worldwide has become a major public health concern, and more than one in four adults fail to follow the minimum recommended levels of participating in 150 min of moderate physical activity (MPA) per week.
This is because the network or cell will need more oxygen when doing activities so that there is adaptation in binding oxygen in the blood. But another study conducted on sedentary women suggest that exercise reduce the red blood cells (RBC), hemoglobin (Hb), and hematocrit (Hct) in sedentary women.
Recently, the prevalence and popularity of high intensity interval exercise (HIIE) among young adults has provided an exciting type of exercise and health promotion intervention. High-intensity interval training (HIT) consisting of short bouts of vigorous intensity exercise, interspersed with low-intensity recovery periods, seems to be the most effective method to improve exercise performance not only in well-trained athletes but also in sedentary and diseased individuals.
Literature shows that there isn't any defined physical activity, which can affect the Hb concentration. Currently no study was found in Pakistan regarding effectiveness of Physical activity on Hemoglobin concentration in young female. Internationally there is also conflicting result about the effect of exercise in increasing or decreasing Hb level. The authors conclude that both high and moderate intensity exercises can improve HB levels in female students. They suggest that the benefits of exercise on HB concentration appear to be more pronounced in those with lower baseline HB levels.
Most of the literature showed that level of physical activity is associated with Hb level. But there is paucity in the literature regarding the cause-and-effect relationship of PA and Hb and any defined physical activity, which can affect the Hb concentration in young female. So objective of the current study is to determine and compare the effectiveness of moderate and vigorous physical activity improving hemoglobin concentration in young female.
- Being tested
- moderate intensity, High intensity
- Medical subject headings
- Lymphoma, Follicular
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
moderate intensityOther
- Arm circles
- Leg swings
- Lunges
High intensityOther
- Arm circles
- Leg swings
- Lunges
- Butt kicks
| Study group | Role | What they receive |
|---|---|---|
| Group A (Moderate Intensity) | Experimental | Warm up protocol to reach max HR 50% than moderate intensity exercise. Group A will be given moderate intensity exercise i.e Brisk walk (HR will be in between 50-60% of max HR) . Receives: Other: moderate intensity |
| Group B (High Intensity) | Experimental | Warm up protocol achieve 70% of max HR. Group B will be given high intensity exercise i.e Skipping rope (HR will be in between 70-85% of max HR). Receives: Other: High intensity |
What is being measured
The primary outcome is the main question the study is designed to answer.
hemoglobin (Hb) level improvement
Changes from the baseline will be measured The amount of hemoglobin in whole blood is expressed in grams per deciliter (g/dl). The normal Hb level for males is 14 to 18 g/dl; that for females is 12 to 16 g/dl.
Measured: 8 weeks
CBC (Complete blood count)
Changes from the baseline will be measured The CBC test identifies and counts the 7 types of cells found in the blood, red blood cell, neutrophil, eosinophil, basophil, lymphocyte, monocyte, and platelet.
Measured: 8 weeks
Pulse oximeter for Heart Rate
Pulse oximeters are often used for estimating heart rate at rest and during exercise.
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Sep 2023
- Study start1 Aug 2023
- Primary completion20 Jan 2024
- Study completion29 Jan 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Moderate and High Intensity Training and Hemoglobin LevelsStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 28 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Tanzeela Rehman, DPT, Principal investigator, Riphah International University Islamabad
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06032806
- Sponsor's protocol ID
- Tanzeela Rehman 41008
- Status last verified
- Mar 2024
- First submitted
- 5 Sep 2023
- Last updated
- 5 Mar 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Mar 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of 8 Weeks Moderate and High Intensity Training on Hemoglobin Levels of Female Students
- ClinicalTrials.gov ID
- NCT06032806
- Acronym / sponsor ID
- Tanzeela Rehman 41008
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 28 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 1 Aug 2023 (actual)
- Primary completion
- 20 Jan 2024 (actual)
- Study completion
- 29 Jan 2024 (actual)
- First posted
- 13 Sep 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimed to assess the effectiveness of 8 weeks of moderate and high intensity training on hemoglobin levels of female students
Detailed description
Anemia is a global health problem and occurs at all stages of the life cycle but is more prevalent among 50% young females of reproductive age and 21% of age group 9-29 years, faces the same problem in Punjab, a province of Pakistan. Higher percentage was found in hostilities (39.2%) as compared to day scholars (23.1%). Anemia has been shown affect to mental development and learning capacity, stress level, may cause irritability, fatigue, difficulty with concentration, lethargy, weakness, and increased susceptibility to infection. Consequently, anemic patients may tend to be poor in quality of life.
Adult men and adult women have different hemoglobin levels in health. This difference is independent of iron status - iron replete pre-menopausal women have mean hemoglobin levels approximately 12% lower than age \& race matched men. National Health and Nutrition Examination Survey (NHANES HI) showed that 9% to11% of adolescent girls and women of child-bearing age were iron-deficient and 2% to5% of them were diagnosed with iron deficiency anemia. Iron deficiency with the presence of low hemoglobin is the criterion for the diagnosis of iron deficiency anemia.There have been frequent reports of a sub-optimal hematological status being observed in athletes involved in intensive physical activity.
Physical activity especially moderate and high intensity reduce mortality and prevent many chronic diseases such as hypertension, diabetes, stroke, and cancer, and stimulate erythropoiesis, which can promote healthy cognitive and psycho-social function and increased hemoglobin concentration Hb lead to increase maximum oxygen carrying capacity. A study reported that aerobic exercise increased hemoglobin (Hb) concentration and hematologic factors in young females.
Recently, the rising prevalence of physical inactivity worldwide has become a major public health concern, and more than one in four adults fail to follow the minimum recommended levels of participating in 150 min of moderate physical activity (MPA) per week.
This is because the network or cell will need more oxygen when doing activities so that there is adaptation in binding oxygen in the blood. But another study conducted on sedentary women suggest that exercise reduce the red blood cells (RBC), hemoglobin (Hb), and hematocrit (Hct) in sedentary women.
Recently, the prevalence and popularity of high intensity interval exercise (HIIE) among young adults has provided an exciting type of exercise and health promotion intervention. High-intensity interval training (HIT) consisting of short bouts of vigorous intensity exercise, interspersed with low-intensity recovery periods, seems to be the most effective method to improve exercise performance not only in well-trained athletes but also in sedentary and diseased individuals.
Literature shows that there isn't any defined physical activity, which can affect the Hb concentration. Currently no study was found in Pakistan regarding effectiveness of Physical activity on Hemoglobin concentration in young female. Internationally there is also conflicting result about the effect of exercise in increasing or decreasing Hb level. The authors conclude that both high and moderate intensity exercises can improve HB levels in female students. They suggest that the benefits of exercise on HB concentration appear to be more pronounced in those with lower baseline HB levels.
Most of the literature showed that level of physical activity is associated with Hb level. But there is paucity in the literature regarding the cause-and-effect relationship of PA and Hb and any defined physical activity, which can affect the Hb concentration in young female. So objective of the current study is to determine and compare the effectiveness of moderate and vigorous physical activity improving hemoglobin concentration in young female.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A (Moderate Intensity) | Experimental | Other: moderate intensityWarm up protocol to reach max HR 50% than moderate intensity exercise. Group A will be given moderate intensity exercise i.e Brisk walk (HR will be in between 50-60% of max HR) . |
| Group B (High Intensity) | Experimental | Other: High intensityWarm up protocol achieve 70% of max HR. Group B will be given high intensity exercise i.e Skipping rope (HR will be in between 70-85% of max HR). |
Who may qualify
- Ages
- 23 to 27 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Age between 18-25 years.
- Hb levels greater than 10 \& less than 12.0 gm/dl
Key exclusion criteria (4 listed)
- Female staff of the institute.
- Students already engaged in physical activity.
- Hb levels greater than 12.0 \& less than 10 gm/dl
- Female having any bony deformity (spine, hip, knee \& ankle)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| moderate intensity* Arm circles * Leg swings * Lunges | Other | Group A (Moderate Intensity) |
| High intensity* Arm circles * Leg swings * Lunges * Butt kicks | Other | Group B (High Intensity) |
Primary outcome
hemoglobin (Hb) level improvement
Time frame: 8 weeks
Changes from the baseline will be measured The amount of hemoglobin in whole blood is expressed in grams per deciliter (g/dl). The normal Hb level for males is 14 to 18 g/dl; that for females is 12 to 16 g/dl.
CBC (Complete blood count)
Time frame: 8 weeks
Changes from the baseline will be measured The CBC test identifies and counts the 7 types of cells found in the blood, red blood cell, neutrophil, eosinophil, basophil, lymphocyte, monocyte, and platelet.
Pulse oximeter for Heart Rate
Time frame: 8 weeks
Pulse oximeters are often used for estimating heart rate at rest and during exercise.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Mar 2024.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Tanzeela Rehman, DPT principal investigator
Riphah International University Islamabad
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing moderate intensity and High intensity in people with Moderate and High Intensity Training and Hemoglobin Levels, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Mar 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
hemoglobin (Hb) level improvement (time frame: 8 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2024.