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Moderate and High Intensity Training and Hemoglobin LevelsNCT06032806

Effects of 8 Weeks Moderate and High Intensity Training on Hemoglobin Levels of Female Students

A study testing moderate intensity and High intensity in people with Moderate and High Intensity Training and Hemoglobin Levels, run by Riphah International University at 1 site in Pakistan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This study aimed to assess the effectiveness of 8 weeks of moderate and high intensity training on hemoglobin levels of female students Read more about this study

Who is it for?
Ages 23 to 27 years, women onlyHealthy volunteers can take part
What is being tested?
moderate intensity and High intensity
Could I receive a placebo?
No, everyone receives an active treatment
How many people
28 participants
Where
1 sitePakistan
Study dates
1 Aug 2023to 29 Jan 2024
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 23 to 27 years
  • Women only
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • Age between 18-25 years.
  • Hb levels greater than 10 \& less than 12.0 gm/dl

Who cannot join

  • Female staff of the institute.
  • Students already engaged in physical activity.
  • Hb levels greater than 12.0 \& less than 10 gm/dl
  • Female having any bony deformity (spine, hip, knee \& ankle)

Trial locations and contacts

1 site in 1 country.

Pakistan1 site
  • Sargodha institute of health sciences

    Sargodha, Punjab Province, 40100

Other trials in Pakistan

About this study

This study aimed to assess the effectiveness of 8 weeks of moderate and high intensity training on hemoglobin levels of female students

Read the detailed description

Anemia is a global health problem and occurs at all stages of the life cycle but is more prevalent among 50% young females of reproductive age and 21% of age group 9-29 years, faces the same problem in Punjab, a province of Pakistan. Higher percentage was found in hostilities (39.2%) as compared to day scholars (23.1%). Anemia has been shown affect to mental development and learning capacity, stress level, may cause irritability, fatigue, difficulty with concentration, lethargy, weakness, and increased susceptibility to infection. Consequently, anemic patients may tend to be poor in quality of life.

Adult men and adult women have different hemoglobin levels in health. This difference is independent of iron status - iron replete pre-menopausal women have mean hemoglobin levels approximately 12% lower than age \& race matched men. National Health and Nutrition Examination Survey (NHANES HI) showed that 9% to11% of adolescent girls and women of child-bearing age were iron-deficient and 2% to5% of them were diagnosed with iron deficiency anemia. Iron deficiency with the presence of low hemoglobin is the criterion for the diagnosis of iron deficiency anemia.There have been frequent reports of a sub-optimal hematological status being observed in athletes involved in intensive physical activity.

Physical activity especially moderate and high intensity reduce mortality and prevent many chronic diseases such as hypertension, diabetes, stroke, and cancer, and stimulate erythropoiesis, which can promote healthy cognitive and psycho-social function and increased hemoglobin concentration Hb lead to increase maximum oxygen carrying capacity. A study reported that aerobic exercise increased hemoglobin (Hb) concentration and hematologic factors in young females.

Recently, the rising prevalence of physical inactivity worldwide has become a major public health concern, and more than one in four adults fail to follow the minimum recommended levels of participating in 150 min of moderate physical activity (MPA) per week.

This is because the network or cell will need more oxygen when doing activities so that there is adaptation in binding oxygen in the blood. But another study conducted on sedentary women suggest that exercise reduce the red blood cells (RBC), hemoglobin (Hb), and hematocrit (Hct) in sedentary women.

Recently, the prevalence and popularity of high intensity interval exercise (HIIE) among young adults has provided an exciting type of exercise and health promotion intervention. High-intensity interval training (HIT) consisting of short bouts of vigorous intensity exercise, interspersed with low-intensity recovery periods, seems to be the most effective method to improve exercise performance not only in well-trained athletes but also in sedentary and diseased individuals.

Literature shows that there isn't any defined physical activity, which can affect the Hb concentration. Currently no study was found in Pakistan regarding effectiveness of Physical activity on Hemoglobin concentration in young female. Internationally there is also conflicting result about the effect of exercise in increasing or decreasing Hb level. The authors conclude that both high and moderate intensity exercises can improve HB levels in female students. They suggest that the benefits of exercise on HB concentration appear to be more pronounced in those with lower baseline HB levels.

Most of the literature showed that level of physical activity is associated with Hb level. But there is paucity in the literature regarding the cause-and-effect relationship of PA and Hb and any defined physical activity, which can affect the Hb concentration in young female. So objective of the current study is to determine and compare the effectiveness of moderate and vigorous physical activity improving hemoglobin concentration in young female.

Being tested
moderate intensity, High intensity
Medical subject headings
Lymphoma, Follicular

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • moderate intensityOther

    • Arm circles
    • Leg swings
    • Lunges
  • High intensityOther

    • Arm circles
    • Leg swings
    • Lunges
    • Butt kicks
Study groups in NCT06032806
Study groupRoleWhat they receive
Group A (Moderate Intensity)ExperimentalWarm up protocol to reach max HR 50% than moderate intensity exercise. Group A will be given moderate intensity exercise i.e Brisk walk (HR will be in between 50-60% of max HR) .
Receives: Other: moderate intensity
Group B (High Intensity)ExperimentalWarm up protocol achieve 70% of max HR. Group B will be given high intensity exercise i.e Skipping rope (HR will be in between 70-85% of max HR).
Receives: Other: High intensity

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. hemoglobin (Hb) level improvement

    Changes from the baseline will be measured The amount of hemoglobin in whole blood is expressed in grams per deciliter (g/dl). The normal Hb level for males is 14 to 18 g/dl; that for females is 12 to 16 g/dl.

    Measured: 8 weeks

  2. CBC (Complete blood count)

    Changes from the baseline will be measured The CBC test identifies and counts the 7 types of cells found in the blood, red blood cell, neutrophil, eosinophil, basophil, lymphocyte, monocyte, and platelet.

    Measured: 8 weeks

  3. Pulse oximeter for Heart Rate

    Pulse oximeters are often used for estimating heart rate at rest and during exercise.

    Measured: 8 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted13 Sep 2023
  2. Study start1 Aug 2023
  3. Primary completion20 Jan 2024
  4. Study completion29 Jan 2024

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Health services research
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Participant
Enrolment
28 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06032806
Sponsor's protocol ID
Tanzeela Rehman 41008
Status last verified
Mar 2024
First submitted
5 Sep 2023
Last updated
5 Mar 2024
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing moderate intensity and High intensity in people with Moderate and High Intensity Training and Hemoglobin Levels, run by Riphah International University at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 5 Mar 2024. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

hemoglobin (Hb) level improvement (time frame: 8 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2024.

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