Gingival RecessionNCT06044870
Clinical Evaluation of the Modified Laterally Stretched Technique (RT2) Gingival Recession vs Tunneling With CT Grafting
A study testing Modified laterally stretched technique with a connective tissue graft. in people with Gingival Recession, run by Cairo University at 1 site in Egypt.
Trial summary
Regression analysis in a recent systematic review showed significantly greater mRC and CRC values when modifications are done to the TUN procedure to achieve more coronal advancement of the flap, coronal advancement also helps in covering the underlying graft for better recession coverage outcomes (Tavelli et al.… Read more about this study
- Who is it for?
- Ages 18 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- Gingival Recession
- What is being tested?
- Modified laterally stretched technique with a connective tissue graft.
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 26 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Oct 2023to 30 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
None listed.
Who cannot join
- Pregnant or lactating females.
- deep recession sites more than 5 mm
- Tobacco smoking.
- Uncontrolled medical conditions.
- Uncooperative patients or unable to complete the study.
- Patients treated with any medication known to cause gingival hyperplasia.
- No occlusal interferences.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Clinical Evaluation of the Modified Laterally Stretched Technique in the Gingival Recession Sites of the Lower Anterior Teeth (RT2) vs Tunneling With Connective Tissue Grafting in Both Techniques: A Randomized Clinical Trial
Regression analysis in a recent systematic review showed significantly greater mRC and CRC values when modifications are done to the TUN procedure to achieve more coronal advancement of the flap, coronal advancement also helps in covering the underlying graft for better recession coverage outcomes (Tavelli et al., 2018), limited data is present on the possible influence of a covered or partially uncovered graft. However, it has been suggested that minimal exposure of the CTG may aid not only in achieving CRC but also a harmonious gingival margin (John et al., 2015; Rasperini et al., 2011).
- Conditions
- Gingival Recession
- Being tested
- Modified laterally stretched technique with a connective tissue graft.
- Medical subject headings
- Gingival Recession
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Modified laterally stretched technique with a connective tissue graft.Procedure or surgery
Modified laterally stretched technique with a connective tissue graft.
| Study group | Role | What they receive |
|---|---|---|
| Modified laterally stretched technique with a connective tissue graft. | Experimental | After the administration of local anesthesia, root planing of the exposed root surfaces will be performed by means of hand instruments.
A partial thickness envelope is performed with tunneling instruments involving one or two teeth adjacent to the tooth, in case of a very thin biotype a complete thickness envelope could be done.
Two horizontal incisions are done at the base of the papillae of the deepest recession site, allowing to place the graft in a more coronal position and improving access and visibility. Receives: Procedure: Modified laterally stretched technique with a connective tissue graft. |
| Tunneling technique with connective tissue graft. | Active comparator | Immediately before surgery, contact point composite stops were placed to prevent the collapse of the suspended sutures in the inter-proximal spaces.• The entire gingival papillary complex will be moved coronally using a suspended suture anchored in the lingual gingiva (Aroca et al., 2010, 2013; Azzi et al, 2002, zuhr et al.,2009). Receives: Procedure: Modified laterally stretched technique with a connective tissue graft. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Recession depth reduction.
Measured as the difference between the recession gingival depth at different follow up intervals and the baseline.
Measured: 1 year
Secondary outcomes (7)
Mean root coverage
(Preoperative vertical recession - Postoperative vertical recession/preoperative vertical recession) x 100
Measured: 1 year
Recession depth
Measured as the distance between the free gingival margin and the cemento-enamel junction .
Measured: 1 year
Recession width
Measured as the distance between the between the mesial gingival margin and distal gingival margin
Measured: 1 year
Soft tissue thickness
The measurement of Gingival tissue thickness is performed 2 mm apical from the gingival margin.
Measured: 1 year
Keratinized tissue width
Measured as the distance between the gingival margin and the muco-gingival junction.
Measured: 1 year
Esthetics (RES) score
A system used to evaluate five variables 6 months gingival margin (GM), marginal tissue contour (MTC), soft tissue texture (STT), MGJ alignment, and gingival color (GC).
Measured: 1 year
patient satisfaction
A 3-item questionnaire is asked, and the patients shall use a 7-point answer scale. The answers were given on a 7-point scale ranging from 1 'not at all'' to 7 ''very likely''.
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Sep 2023
- Study start1 Oct 2023
- Primary completion30 Oct 2025
- Study completion30 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Gingival RecessionStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 26 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Maha fawzy el sayed ali abd allah, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06044870
- Sponsor's protocol ID
- 21021992
- Status last verified
- Oct 2026
- First submitted
- 12 Sep 2023
- Last updated
- 14 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Evaluation of the Modified Laterally Stretched Technique in the Gingival Recession Sites of the Lower Anterior Teeth (RT2) vs Tunneling With Connective Tissue Grafting in Both Techniques: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT06044870
- Acronym / sponsor ID
- 21021992
- Conditions
- Gingival Recession
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 26 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Oct 2023 (actual)
- Primary completion
- 30 Oct 2025 (actual)
- Study completion
- 30 Oct 2025 (actual)
- First posted
- 21 Sep 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Regression analysis in a recent systematic review showed significantly greater mRC and CRC values when modifications are done to the TUN procedure to achieve more coronal advancement of the flap, coronal advancement also helps in covering the underlying graft for better recession coverage outcomes (Tavelli et al., 2018), limited data is present on the possible influence of a covered or partially uncovered graft. However, it has been suggested that minimal exposure of the CTG may aid not only in achieving CRC but also a harmonious gingival margin (John et al., 2015; Rasperini et al., 2011).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Modified laterally stretched technique with a connective tissue graft. | Experimental | Procedure: Modified laterally stretched technique with a connective tissue graft.After the administration of local anesthesia, root planing of the exposed root surfaces will be performed by means of hand instruments. A partial thickness envelope is performed with tunneling instruments involving one or two teeth adjacent to the tooth, in case of a very thin biotype a complete thickness envelope could be done. Two horizontal incisions are done at the base of the papillae of the deepest recession site, allowing to place the graft in a more coronal position and improving access and visibility. |
| Tunneling technique with connective tissue graft. | Active comparator | Procedure: Modified laterally stretched technique with a connective tissue graft.Immediately before surgery, contact point composite stops were placed to prevent the collapse of the suspended sutures in the inter-proximal spaces.• The entire gingival papillary complex will be moved coronally using a suspended suture anchored in the lingual gingiva (Aroca et al., 2010, 2013; Azzi et al, 2002, zuhr et al.,2009). |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (0 listed)
Key exclusion criteria (7 listed)
- Pregnant or lactating females.
- deep recession sites more than 5 mm
- Tobacco smoking.
- Uncontrolled medical conditions.
- Uncooperative patients or unable to complete the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Modified laterally stretched technique with a connective tissue graft.Modified laterally stretched technique with a connective tissue graft. | Procedure or surgery | Modified laterally stretched technique with a connective tissue graft., Tunneling technique with connective tissue graft. |
Primary outcome
Recession depth reduction.
Time frame: 1 year
Measured as the difference between the recession gingival depth at different follow up intervals and the baseline.
7 secondary outcomes
Mean root coverage
Time frame: 1 year
Recession depth
Time frame: 1 year
Recession width
Time frame: 1 year
Soft tissue thickness
Time frame: 1 year
Keratinized tissue width
Time frame: 1 year
Esthetics (RES) score
Time frame: 1 year
patient satisfaction
Time frame: 1 year
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Modified laterally stretched technique with a connective tissue graft. in people with Gingival Recession, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 14 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Recession depth reduction. (time frame: 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Oct 2026.