CardiopulmonaryNCT06060145
Effect of Indoor Plants on Cardiopulmonary System
A study testing Plants placed in an office environment and Devoid of any plant presence in an office environment in people with Cardiopulmonary, run by Lina Zhang at 1 site in China.
Trial summary
This is a randomized controlled human exposure crossover study, aims to explore the health benefits of indoor plants on cardiopulmonary system on adults. Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Cardiopulmonary
- What is being tested?
- Plants placed in an office environment and Devoid of any plant presence in an office environment
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 41 participants
- Where
- 1 siteChina
- Study dates
- 21 Dec 2023to 31 Mar 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Living in Hangzhou during the study period;
- Non-smoking, no history of alcohol or drug abuse;
- Staying indoors in daytime we required.
Who cannot join
- Current or ever smokers;
- Subjects with allergic disease, such as allergic rhinitis, allergic asthma, and atopy;
- Subjects with cardiovascular disease, such as congenital heart disease, pulmonary heart disease, and hypertension;
- Subjects with respiratory disease, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease;
- Subjects with chronic disease, such as diabetes, chronic hepatitis, and kidney disease;
- Subjects with a history of major surgery;
- Medication use or dietary supplements intake in recent two months;
- Unable to cooperate with follow-up.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Indoor Plants on Cardiopulmonary System: a Randomized, Crossover, Controlled Trial
This is a randomized controlled human exposure crossover study, aims to explore the health benefits of indoor plants on cardiopulmonary system on adults.
Read the detailed description
The researchers will conduct a randomized cross-controlled trial involving 48 healthy adults in Hangzhou, China. These participants will be randomly assigned into two groups, each comprising 24 individuals. Each participant will undergo two separate exposures in an office setting: one exposure without any plants present, and another exposure with 34 to 38 potted plants. A washout period of at least 4 weeks will be implemented between the two exposures. Questionnaires, physical examinations and the collection of biological samples will be conducted prior to exposure and after exposure. In addition, the monitoring of negative air ion, air pollutants and noise exposure, as well as collection of environmental microbial samples, will be conducted on weekdays. Researchers will gather samples of blood, urine, nasal secretion, and exhaled breath condensate from participants.
- Conditions
- Cardiopulmonary
- Being tested
- Plants placed in an office environment, Devoid of any plant presence in an office environment
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Plants placed in an office environmentOther
The intervention group will be provided with an intervention consisting of 34-38 potted plants arranged in an office environment for a duration of 8 hours (09:00-17:00) on weekdays (Monday to Friday) for 4 weeks.
Devoid of any plant presence in an office environmentOther
Participants assigned to the control group will be exposed to an office environment devoid of any plant presence for a duration of 8 hours (09:00-17:00) on weekdays (Monday to Friday) for 4 weeks.
| Study group | Role | What they receive |
|---|---|---|
| Plants placed in an office environment | Experimental | Participants in this group will receive an intervention of plants placed in an office environment. Receives: Other: Plants placed in an office environment |
| Devoid of any plant presence in an office environment | Active comparator | Participants in this group will be exposed to an office environment devoid of any plant presence. Receives: Other: Devoid of any plant presence in an office environment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Forced Vital Capacity(FVC)
We plan to measure forced vital capacity (FVC) of lung function.
Measured: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.
Secondary outcomes (2)
Blood Pressure(BP)
We plan to measure systolic blood pressure (SBP) and diastolic blood pressure (DBP).
Measured: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.
Heart Rate Variability(HRV)
We plan to measure Heart Rate Variability (HRV).
Measured: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Sep 2023
- Study start21 Dec 2023
- Primary completion29 Mar 2024
- Study completion31 Mar 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CardiopulmonaryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 41 participants (actual)
Sponsor and investigators
- Lead sponsor
- Lina Zhang
- Sponsor type
- Other government
- Collaborators
- Zhejiang Chinese Medical University
- Responsible party
- Sponsor-investigator, Lina Zhang, Zhejiang Chinese Medical University
- Investigators
- Lina Zhang, Ph.D, Principal investigator, School of Public Health, Zhejiang Chinese Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06060145
- Sponsor's protocol ID
- 20230922-4
- Status last verified
- Jul 2024
- First submitted
- 23 Sep 2023
- Last updated
- 25 Jul 2024
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Jul 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Indoor Plants on Cardiopulmonary System: a Randomized, Crossover, Controlled Trial
- ClinicalTrials.gov ID
- NCT06060145
- Acronym / sponsor ID
- 20230922-4
- Conditions
- Cardiopulmonary
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 41 participants (actual)
- Lead sponsor
- Lina ZhangOther government
- Collaborators
- Zhejiang Chinese Medical University
- Study start
- 21 Dec 2023 (actual)
- Primary completion
- 29 Mar 2024 (actual)
- Study completion
- 31 Mar 2024 (actual)
- First posted
- 29 Sep 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a randomized controlled human exposure crossover study, aims to explore the health benefits of indoor plants on cardiopulmonary system on adults.
Detailed description
The researchers will conduct a randomized cross-controlled trial involving 48 healthy adults in Hangzhou, China. These participants will be randomly assigned into two groups, each comprising 24 individuals. Each participant will undergo two separate exposures in an office setting: one exposure without any plants present, and another exposure with 34 to 38 potted plants. A washout period of at least 4 weeks will be implemented between the two exposures. Questionnaires, physical examinations and the collection of biological samples will be conducted prior to exposure and after exposure. In addition, the monitoring of negative air ion, air pollutants and noise exposure, as well as collection of environmental microbial samples, will be conducted on weekdays. Researchers will gather samples of blood, urine, nasal secretion, and exhaled breath condensate from participants.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Plants placed in an office environment | Experimental | Other: Plants placed in an office environmentParticipants in this group will receive an intervention of plants placed in an office environment. |
| Devoid of any plant presence in an office environment | Active comparator | Other: Devoid of any plant presence in an office environmentParticipants in this group will be exposed to an office environment devoid of any plant presence. |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Living in Hangzhou during the study period;
- Non-smoking, no history of alcohol or drug abuse;
- Staying indoors in daytime we required.
Key exclusion criteria (8 listed)
- Current or ever smokers;
- Subjects with allergic disease, such as allergic rhinitis, allergic asthma, and atopy;
- Subjects with cardiovascular disease, such as congenital heart disease, pulmonary heart disease, and hypertension;
- Subjects with respiratory disease, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease;
- Subjects with chronic disease, such as diabetes, chronic hepatitis, and kidney disease;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Plants placed in an office environmentThe intervention group will be provided with an intervention consisting of 34-38 potted plants arranged in an office environment for a duration of 8 hours (09:00-17:00) on weekdays (Monday to Friday) for 4 weeks. | Other | Plants placed in an office environment |
| Devoid of any plant presence in an office environmentParticipants assigned to the control group will be exposed to an office environment devoid of any plant presence for a duration of 8 hours (09:00-17:00) on weekdays (Monday to Friday) for 4 weeks. | Other | Devoid of any plant presence in an office environment |
Primary outcome
Forced Vital Capacity(FVC)
Time frame: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.
We plan to measure forced vital capacity (FVC) of lung function.
2 secondary outcomes
Blood Pressure(BP)
Time frame: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.
Heart Rate Variability(HRV)
Time frame: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jul 2024.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Lina Zhang, Ph.D principal investigator
School of Public Health, Zhejiang Chinese Medical University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Plants placed in an office environment and Devoid of any plant presence in an office environment in people with Cardiopulmonary, run by Lina Zhang at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Jul 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Forced Vital Capacity(FVC) (time frame: Baseline and after 4 weeks plants exposure in first stage, and after washout period, baseline and after 4 weeks plants exposure in second stage.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jul 2024.