HealthyNCT06074523

Psychometric Testing: Cued vs. Learned Suppression

A study testing Behavioral Measurement and self-report in people with Healthy, run by Lehigh University at 1 site in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

In this line of research, the researchers are examining whether performance on a cued attentional suppression (ignoring) task is related to performance on a learned attentional suppression task. In addition, these measures are related to the capacity of working memory and every day inattentive traits. Read more about this study

Who is it for?: Ages 18 years and olderHealthy volunteers can take part
Conditions the study is for: Healthy
What is being tested?: Behavioral Measurement and self-report
Type of treatment: Lifestyle or therapy programme
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 75 participants
Where: 1 siteUnited States
Study dates: 2 Nov 2022to 10 Mar 2023
Phase: Interventional
Are there results?: Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 years and older
All sexes
Healthy volunteers accepted
Adult, Older adult

Who may be able to join

Normal or corrected-to-normal visual acuity, normal color vision

Who cannot join

Trial locations and contacts

1 site in 1 country.

United States1 site

Lehigh University
Bethlehem, Pennsylvania, 18015

Other trials in United States

About this study

Read the detailed description

This is a behavioral study. The researchers will measures performance on multiple tasks. 1) a cued attentional suppression task, where participants are told the color of the item they are supposed to ignore on each trial. 2) a learned attentional suppression task, where participants learn over experience that a particular color is not the target. 3) a visual working memory capacity measurement 4) an inattentive trait report task, where participants report their experiences of inattention during their daily lives.

Conditions: Healthy
Being tested: Behavioral Measurement and self-report
Keywords: attention

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Behavioral Measurement and self-reportBehavioural
Measurements of behavioral performance and self-report

Study groups in NCT06074523
Study group	Role	What they receive
Attention and Working Memory Tests	Experimental	All participants will complete a series of behavioral tasks, including cued visual search with positive (target color), negative (distractor color) and neutral (baseline) cues, learned visual search with a repeated salient distractor color, a visual working memory capacity task, and a daily life inattentive traits questionnaire (self-report). Single Arm. Receives: Behavioral: Behavioral Measurement and self-report

What is being measured

The primary outcome is the main question the study is designed to answer.

Button Press Reaction Time
Reaction times on visual search task with positive, negative, and neutral cues
Measured: 1 day
Learned Suppression Task
Reaction times on visual search task no salient distractor and learned salient distractor
Measured: 1 day
Visual Working Memory Capacity
Visual Working Memory Capacity- Change Localization; Estimate of number of items maintained in working memory
Measured: 1 day
Inattentive Traits Subscale of Adult Attention Deficit Hyperactivity Disorder (ADHD) Self Report Scale
Adult Attention Deficit Hyperactivity Disorder (ADHD) Self Report Scale (used on healthy adults), Inattentive Traits subscale. Higher values indicate more ADHD-like inattentive trait symptoms (0-45).
Measured: 1 day

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

2 Nov 202210 Mar 2023

First posted10 Oct 2023
Study start2 Nov 2022
Primary completion10 Mar 2023
Study completion10 Mar 2023

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
Publications (1)Papers the sponsor has linked to this study.
Other trials for HealthyStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Basic science
Allocation: Not applicable
Intervention model: Single group
Model description: Within-subjects measures, correlational analysis
Masking: None (open label)
Enrolment: 75 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT06074523
Sponsor's protocol ID: 9R15EY030247-01A1
Status last verified: Mar 2025
First submitted: 3 Oct 2023
Last updated: 12 Mar 2025
Results posted: Yes, on ClinicalTrials.gov
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: Yes: Anonymous behavioral performance data will be available for other researchers upon request

Publications

Arita JT, Carlisle NB, Woodman GF. Templates for rejection: configuring attention to ignore task-irrelevant features. J Exp Psychol Hum Percept Perform. 2012 Jun;38(3):580-4. doi: 10.1037/a0027885. Epub 2012 Apr 2.
PubMed 22468723

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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Study at a glance

From the registry record, last updated by the sponsor on 12 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Psychometric Testing: Cued vs. Learned Suppression
ClinicalTrials.gov ID: NCT06074523
Acronym / sponsor ID: 9R15EY030247-01A1
Conditions: Healthy
Keywords: attention
Study type: Interventional
Recruitment status: Completed
Enrolment: 75 participants (actual)
Lead sponsor: Lehigh UniversityUniversity, hospital or other
Study start: 2 Nov 2022 (actual)
Primary completion: 10 Mar 2023 (actual)
Study completion: 10 Mar 2023 (actual)
First posted: 10 Oct 2023 (actual)
Results: Posted 19 Nov 2024

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

Study design

Primary purpose: Basic science
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Number of arms: 1
Model description: Within-subjects measures, correlational analysis

Arm	Type	Receives
Attention and Working Memory Tests	Experimental	Behavioral: Behavioral Measurement and self-reportAll participants will complete a series of behavioral tasks, including cued visual search with positive (target color), negative (distractor color) and neutral (baseline) cues, learned visual search with a repeated salient distractor color, a visual working memory capacity task, and a daily life inattentive traits questionnaire (self-report). Single Arm.

Who may qualify

Ages: 18 years and older
Sex: All
Healthy volunteers: Accepted
Age groups: Adult, Older adult

Key inclusion criteria (1 listed)

Normal or corrected-to-normal visual acuity, normal color vision

Key exclusion criteria (1 listed)

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Behavioral Measurement and self-reportMeasurements of behavioral performance and self-report	Behavioural	Attention and Working Memory Tests

Primary outcome

Button Press Reaction Time
Time frame: 1 day
Reaction times on visual search task with positive, negative, and neutral cues
Learned Suppression Task
Time frame: 1 day
Reaction times on visual search task no salient distractor and learned salient distractor
Visual Working Memory Capacity
Time frame: 1 day
Visual Working Memory Capacity- Change Localization; Estimate of number of items maintained in working memory
Inattentive Traits Subscale of Adult Attention Deficit Hyperactivity Disorder (ADHD) Self Report Scale
Time frame: 1 day
Adult Attention Deficit Hyperactivity Disorder (ADHD) Self Report Scale (used on healthy adults), Inattentive Traits subscale. Higher values indicate more ADHD-like inattentive trait symptoms (0-45).

Results and safety

Results posted to the registry on 19 Nov 2024, as reported by the sponsor. Figures are copied from the record, not re-analysed. Full results on ClinicalTrials.gov.

Participant flow

Group	Started	Completed
Attention and Working Memory Tests	75	65

Primary outcome: Button Press Reaction Time

Time frame: 1 day. Mean (Standard Deviation). Unit: Seconds

Measure	Attention and Working Memory Tests n = 54
Neutral Condition	1.86 (.77)
Negative Condition	1.53 (.57)
Positive Condition	1.29 (.49)

Attention and Working Memory Tests: partial eta squared: .81, p <.001, ANOVA

Population analysed: 21 participants were excluded for either bad accuracy in one of the cognitive tasks (n = 11) or for incomplete data recording (n = 10).

Primary outcome: Learned Suppression Task

Time frame: 1 day. Mean (Standard Deviation). Unit: Reaction time (seconds)

Measure	Attention and Working Memory Tests n = 54
Singleton Absent condition	1.014 (.315)
Singleton Present condition	1.001 (.294)

Attention and Working Memory Tests: cohen's d: .24, p = .08, t-test, 2 sided

Population analysed: 21 participants were excluded for either bad accuracy in one of the cognitive tasks (n = 11) or for incomplete data recording (n = 10).

Primary outcome: Visual Working Memory Capacity

Time frame: 1 day. Mean (Standard Deviation). Unit: Number of items remembered

Measure	Attention and Working Memory Tests n = 54
Value	2.85 (.70)

Attention and Working Memory Tests: Slope: -.37 (95% CI -0.5803 to -0.1135), p = .007, correlation

Population analysed: 21 participants were excluded for either bad accuracy in one of the cognitive tasks (n = 11) or for incomplete data recording (n = 10).

Primary outcome: Inattentive Traits Subscale of Adult Attention Deficit Hyperactivity Disorder (ADHD) Self Report Scale

Time frame: 1 day. Mean (Standard Deviation). Unit: units on scale

Measure	Attention and Working Memory Tests n = 54
Value	18.1 (5.40)

Attention and Working Memory Tests: Slope: -.27 (95% CI -0.5015 to -0.002414), p = .046, correlation

Population analysed: 21 participants were excluded for either bad accuracy in one of the cognitive tasks (n = 11) or for incomplete data recording (n = 10).

Adverse events

Time frame: Participants were monitored during the testing session, which occurred during one day.. Other adverse events reported at 0% frequency or more

Group	Serious adverse events	Other adverse events	Deaths
Attention and Working Memory Tests	0 of 75 (0%)	1 of 75 (1.3%)	0 of 75

Loading the posted results from ClinicalTrials.gov…

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 12 Mar 2025.
Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
Background: PubMed 22468723Arita JT, Carlisle NB, Woodman GF. Templates for rejection: configuring attention to ignore task-irrelevant features. J Exp Psychol Hum Percept Perform. 2012 Jun;38(3):580-4. doi: 10.1037/a0027885. Epub 2012 Apr 2.
Individual participant dataSharing planned: Yes. Anonymous behavioral performance data will be available for other researchers upon request

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A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Children
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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Nancy Carlisle, PhD principal investigator

Lehigh University

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Behavioral Measurement and self-report in people with Healthy, run by Lehigh University at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 12 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 19 Nov 2024). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Button Press Reaction Time (time frame: 1 day). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06074523, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Mar 2025.