PainDEAMPTNCT06074575
Do Emotions Affect Mechanical Pain Thresholds?
A study testing Emotion induction in people with Pain, run by Linnaeus University at 1 site in Sweden.
Trial summary
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Pain
- What is being tested?
- Emotion induction
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 152 participants
- Where
- 1 siteSweden
- Study dates
- 1 Oct 2023to 22 May 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Above 18 years of age, fluent in Swedish.
Who cannot join
- Pain anywhere in body during the test session, known neurological disease.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effect of Positive and Negative Emotions on Mechanical Pain Thresholds: a Randomized Controlled Trial
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds.
Read the detailed description
Participants will be randomized into 4 different groups watching different short video-clips (2.20 min). The negative emotions group will watch an uncomfortable short video containing violence and blood, the positive emotions group will watch a video containing a stand-up comedy show, the neutral emotions group will watch a video with Swedish nature, and the control group will just wait for 2.20 min, without any instructions about what to think about. Pressure pain thresholds will be measured with an algometer before and after the video-clip interventions.
- Conditions
- Pain
- Being tested
- Emotion induction
- Medical subject headings
- Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Emotion inductionBehavioural
The participants will receive different emotion inductions through short video clips.
| Study group | Role | What they receive |
|---|---|---|
| Negative emotional condition | Experimental | The participant will watch a short video-clip with negative emotional content. Receives: Behavioral: Emotion induction |
| Positive emotional condition. | Experimental | The participant will watch a short video-clip with positive emotional content. Receives: Behavioral: Emotion induction |
| Neutral condition. | Experimental | The participant will watch a short video-clip with neutral emotional content. Receives: Behavioral: Emotion induction |
| Control condition. | Experimental | The participant will not watch a video-clip, but will wait without specific instructions about what to think about. Receives: Behavioral: Emotion induction |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pressure pain threshold
Pressure pain threshold value after each different emotion intervention and control compared to before each emotion intervention and control.
Measured: Measurements will be conducted at the test session, which will have a duration of approximately 20 minutes for each participant.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Oct 2023
- Study start1 Oct 2023
- Primary completion10 May 2024
- Study completion22 May 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Sequential
- Model description
- Within-subjects design.
- Masking
- None (open label)
- Enrolment
- 152 participants (actual)
Sponsor and investigators
- Lead sponsor
- Linnaeus University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Helena Gunnarsson, Linnaeus University
- Investigators
- Helena Gunnarsson, PhD, Principal investigator, Linnéuniversitetet
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06074575
- Sponsor's protocol ID
- 2023-03968-01
- Other IDs
- 2023
- Acronym
- DEAMPT
- Status last verified
- Oct 2023
- First submitted
- 3 Oct 2023
- Last updated
- 14 Feb 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Data is available after study completion.
Study at a glance
From the registry record, last updated by the sponsor on 14 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Positive and Negative Emotions on Mechanical Pain Thresholds: a Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT06074575
- Acronym / sponsor ID
- DEAMPT / 2023-03968-01
- Conditions
- Pain
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 152 participants (actual)
- Lead sponsor
- Linnaeus UniversityUniversity, hospital or other
- Study start
- 1 Oct 2023 (actual)
- Primary completion
- 10 May 2024 (actual)
- Study completion
- 22 May 2024 (actual)
- First posted
- 10 Oct 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds.
Detailed description
Participants will be randomized into 4 different groups watching different short video-clips (2.20 min). The negative emotions group will watch an uncomfortable short video containing violence and blood, the positive emotions group will watch a video containing a stand-up comedy show, the neutral emotions group will watch a video with Swedish nature, and the control group will just wait for 2.20 min, without any instructions about what to think about. Pressure pain thresholds will be measured with an algometer before and after the video-clip interventions.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Sequential
- Masking
- None (open label)
- Number of arms
- 4
- Model description
- Within-subjects design.
| Arm | Type | Receives |
|---|---|---|
| Negative emotional condition | Experimental | Behavioral: Emotion inductionThe participant will watch a short video-clip with negative emotional content. |
| Positive emotional condition. | Experimental | Behavioral: Emotion inductionThe participant will watch a short video-clip with positive emotional content. |
| Neutral condition. | Experimental | Behavioral: Emotion inductionThe participant will watch a short video-clip with neutral emotional content. |
| Control condition. | Experimental | Behavioral: Emotion inductionThe participant will not watch a video-clip, but will wait without specific instructions about what to think about. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Above 18 years of age, fluent in Swedish.
Key exclusion criteria (1 listed)
- Pain anywhere in body during the test session, known neurological disease.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Emotion inductionThe participants will receive different emotion inductions through short video clips. | Behavioural | Control condition., Negative emotional condition, Neutral condition., Positive emotional condition. |
Primary outcome
Pressure pain threshold
Time frame: Measurements will be conducted at the test session, which will have a duration of approximately 20 minutes for each participant.
Pressure pain threshold value after each different emotion intervention and control compared to before each emotion intervention and control.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Feb 2025.
- Individual participant dataSharing planned: Yes. Data is available after study completion.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Helena Gunnarsson, PhD principal investigator
Linnéuniversitetet
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Emotion induction in people with Pain, run by Linnaeus University at 1 site in Sweden.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 14 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pressure pain threshold (time frame: Measurements will be conducted at the test session, which will have a duration of approximately 20 minutes for each participant.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Feb 2025.