HemodialysisNCT06098924
HD Patients' Depression and Happiness
An observational study of Hemodialysis, run by Chang Gung University of Science and Technology at 1 site in Taiwan.
Trial summary
The aim of the study is to verify the mediating effect of life of meaning and post-traumatic growth in spirituality and psychological well-being (happiness, depression). Read more about this study
- Who is it for?
- Ages 20 to 90 years
- Conditions the study is for
- Hemodialysis
- How many people
- 392 participants
- Where
- 1 siteTaiwan
- Study dates
- 10 Sep 2023to 31 Jul 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 90 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: adults with regularly hemodylysis
Who may be able to join
- Patients who are over 20 years old
- voluntarily participate in the study and sign the respondent consent form
- have received routine hemodialysis treatment for more than three months
- have clear consciousness and can communicate in Mandarin and Taiwanese.
Who cannot join
- Patients whose medical records record a diagnosis of schizophrenia
- patients are taking antidepressant drugs
Trial locations and contacts
1 site in 1 country.
Taiwan1 site
Chang Gung University of Science and Technology
Taoyuan City, N/A = Not Applicable, 333 03
About this study
Official title: The Impacts of Spiritual Health on Depression and Happiness Among Hemodialysis Patients: the Moderator Effects of Life-meaning and Post-trauma Growth
The aim of the study is to verify the mediating effect of life of meaning and post-traumatic growth in spirituality and psychological well-being (happiness, depression).
Read the detailed description
The research design is cross-sectional correlational study. Convenient sampling will be used to conduct to data collection. There are 300 patients with hemodialysis from a hemodialysis institution in the north Taiwan, and data collecting with self-administrated questionnaires. The instruments include demographic and disease-related information, Spiritual Health Scale short form, Chinese Happiness Inventory, Beck Depression Inventory-II, Life Attitude Profile, Posttraumatic Growth Inventory. The SPSS 22.0 statistical software will be used to analyze the data. Descriptive statistics, such as frequency, percentage, mean, and standard deviation (SD) will be used for participant characteristics and outcome measures. T-test, chi-square, ANOVA, post-hoc, ANCOVA, and Person's correlation will be conducted to test the relationships between the research variables.
- Conditions
- Hemodialysis
- Keywords
- spirituality, depression, happiness, post-trauma growth, life meaning
- Medical subject headings
- Depression
What is being measured
The primary outcome is the main question the study is designed to answer.
The status of spirituality among HD patients
Self-administrated questionnaire of Spiritual Health Scale short form was used to collect data. The score range is 24 to 120, and the higher score means higher spirituality.
Measured: 1 day
The status of life-meaning among HD patients
Self-administrated questionnaire of Life Attitude Profile was used to collect data. The score range is 39 to 195, and the higher score means higher level of life-meaning.
Measured: 1 day
The status of post-trauma growth among HD patients
Self-administrated questionnaire of Posttraumatic Growth Inventory was used to collect data. The score range is 0 to 105, and the higher score means higher level of post-trauma growth.
Measured: 1 day
The status of depression among HD patients
Self-administrated questionnaire of Beck Depression Inventory-II was used to collect data. The score range is 0 to 63, and the higher score means higher level of depressive tendency.
Measured: 7 minutes
The status of happiness among HD patients
Self-administrated questionnaire of Chinese Happiness Inventory was used to collect data. The score range is 0 to 30, and the higher score means higher level of happiness.
Measured: 1 day
The mediating effect of life of meaning and post-traumatic growth
Using these scores form these scales (mention above) to verify the mediating effect of life of meaning and post-traumatic growth in spirituality and psychological well-being (including happiness, depression).
Measured: 1 day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Oct 2023
- Study start10 Sep 2023
- Primary completion30 Jun 2024
- Study completion31 Jul 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for HemodialysisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 392 participants (actual)
Sponsor and investigators
- Lead sponsor
- Chang Gung University of Science and Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ya-Chu Hsiao, Chang Gung University of Science and Technology
- Investigators
- yachu hsiao, Principal investigator, Chang Gung University of Science and Technology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06098924
- Sponsor's protocol ID
- NSCT-112-2014-H-255-009
- Status last verified
- Oct 2026
- First submitted
- 15 Oct 2023
- Last updated
- 21 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Lee HC, Chiang YC, Tsai KH, Okoli C, Chu TL, Hsiao YC. Spirituality and Happiness in Haemodialysis Patients: The Mediating Roles of Life Attitude and Posttraumatic Growth. Nurs Open. 2026 Mar;13(3):e70479. doi: 10.1002/nop2.70479.
PubMed 41804610
Study at a glance
From the registry record, last updated by the sponsor on 21 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Impacts of Spiritual Health on Depression and Happiness Among Hemodialysis Patients: the Moderator Effects of Life-meaning and Post-trauma Growth
- ClinicalTrials.gov ID
- NCT06098924
- Acronym / sponsor ID
- NSCT-112-2014-H-255-009
- Conditions
- Hemodialysis
- Keywords
- spirituality, depression, happiness, post-trauma growth, life meaning
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 392 participants (actual)
- Lead sponsor
- Chang Gung University of Science and TechnologyUniversity, hospital or other
- Study start
- 10 Sep 2023 (actual)
- Primary completion
- 30 Jun 2024 (actual)
- Study completion
- 31 Jul 2024 (actual)
- First posted
- 25 Oct 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the study is to verify the mediating effect of life of meaning and post-traumatic growth in spirituality and psychological well-being (happiness, depression).
Detailed description
The research design is cross-sectional correlational study. Convenient sampling will be used to conduct to data collection. There are 300 patients with hemodialysis from a hemodialysis institution in the north Taiwan, and data collecting with self-administrated questionnaires. The instruments include demographic and disease-related information, Spiritual Health Scale short form, Chinese Happiness Inventory, Beck Depression Inventory-II, Life Attitude Profile, Posttraumatic Growth Inventory. The SPSS 22.0 statistical software will be used to analyze the data. Descriptive statistics, such as frequency, percentage, mean, and standard deviation (SD) will be used for participant characteristics and outcome measures. T-test, chi-square, ANOVA, post-hoc, ANCOVA, and Person's correlation will be conducted to test the relationships between the research variables.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 20 to 90 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- adults with regularly hemodylysis
Key inclusion criteria (4 listed)
- Patients who are over 20 years old
- voluntarily participate in the study and sign the respondent consent form
- have received routine hemodialysis treatment for more than three months
- have clear consciousness and can communicate in Mandarin and Taiwanese.
Key exclusion criteria (2 listed)
- Patients whose medical records record a diagnosis of schizophrenia
- patients are taking antidepressant drugs
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
The status of spirituality among HD patients
Time frame: 1 day
Self-administrated questionnaire of Spiritual Health Scale short form was used to collect data. The score range is 24 to 120, and the higher score means higher spirituality.
The status of life-meaning among HD patients
Time frame: 1 day
Self-administrated questionnaire of Life Attitude Profile was used to collect data. The score range is 39 to 195, and the higher score means higher level of life-meaning.
The status of post-trauma growth among HD patients
Time frame: 1 day
Self-administrated questionnaire of Posttraumatic Growth Inventory was used to collect data. The score range is 0 to 105, and the higher score means higher level of post-trauma growth.
The status of depression among HD patients
Time frame: 7 minutes
Self-administrated questionnaire of Beck Depression Inventory-II was used to collect data. The score range is 0 to 63, and the higher score means higher level of depressive tendency.
The status of happiness among HD patients
Time frame: 1 day
Self-administrated questionnaire of Chinese Happiness Inventory was used to collect data. The score range is 0 to 30, and the higher score means higher level of happiness.
The mediating effect of life of meaning and post-traumatic growth
Time frame: 1 day
Using these scores form these scales (mention above) to verify the mediating effect of life of meaning and post-traumatic growth in spirituality and psychological well-being (including happiness, depression).
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Oct 2026.
- Derived from this study: PubMed 41804610Lee HC, Chiang YC, Tsai KH, Okoli C, Chu TL, Hsiao YC. Spirituality and Happiness in Haemodialysis Patients: The Mediating Roles of Life Attitude and Posttraumatic Growth. Nurs Open. 2026 Mar;13(3):e70479. doi: 10.1002/nop2.70479.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
yachu hsiao principal investigator
Chang Gung University of Science and Technology
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Hemodialysis, run by Chang Gung University of Science and Technology at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The status of spirituality among HD patients (time frame: 1 day). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06098924, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Oct 2026; AzTrials last refreshed its copy on 26 Oct 2026.