Temporomandibular Joint Dysfunction SyndromeNCT06148818
Effect of Progressive Neck Motor Control Exercises on Temporomandibular Joint Dysfunction
A study testing Patient education in people with Temporomandibular Joint Dysfunction Syndrome, run by Karadeniz Technical University at 1 site in Turkey (Türkiye).
Trial summary
The primary aim of this study was to investigate the effects of progressive neck motor control exercises on craniocervical pain, posture, function and kinesiophobia in different types of temporomandibular dysfunction. Read more about this study
- Who is it for?
- Ages 18 to 55 yearsHealthy volunteers can take part
- Conditions the study is for
- Temporomandibular Joint Dysfunction Syndrome
- What is being tested?
- Patient education
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 75 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 4 Nov 2024to 30 Jun 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 55 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- 18 to 55 years old,
- Temporomandibular joint-related complaints for at least 3 months,
- Temporomandibular dysfunction is diagnosed as a result of clinical and radiological evaluation by the dentist,
- Neck pain of 3 or more according to the numeric pain scale
Who cannot join
- Cognitive problems,
- The one with the splint,
- Those who have used painkillers or muscle relaxants for temporomandibular dysfunction complaints in the last 1 week,
- With any systematic joint or muscle disease (e.g. fibromyalgia, rheumatoid arthritis),
- Those with serious systemic diseases,
- Any neurological disorder (e.g. trigeminal neuralgia),
Show all 10Show fewer
- Pregnancy or breastfeeding,
- Treated for Temporomandibular joint or orofacial muscle pain in the last 3 months,
- Has undergone an operation/trauma to the cervical region and/or temporomandibular joint,
- Positive vertebrobasilar artery test
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Karadeniz Technical University
Trabzon
Nurhayat Korkmaz, Msc, +90462377 ext. 2471
Nurhayat korkmaz, Msc
About this study
Official title: Investigation of the Effect of Progressive Neck Motor Control Exercises on Craniocervical Pain, Posture, Function and Kinesiophobia in Different Types of Temporomandibular Joint Dysfunction
The primary aim of this study was to investigate the effects of progressive neck motor control exercises on craniocervical pain, posture, function and kinesiophobia in different types of temporomandibular dysfunction. The secondary aim of the study was to examine the differences between the effects of progressive neck motor control exercises on different types of temporomandibular dysfunction.
Read the detailed description
In this randomised controlled study, the effects of progressive neck motor control exercise therapy on craniocervical pain, posture, function and kinesiophobia in individuals with different types of temporomandibular dysfunction (myofascial, disc displacement with reduction, disc displacement without reduction) and their differences with the control group will be compared. Participants diagnosed by a dentist according to three different types of temporomandibular dysfunction will be included in the study. Participants will be divided into groups by block randomisation method. A total of 6 groups will be included in the study, including participants with three different types of temporomandibular dysfunction who voluntarily agree to participate in the study and meet the inclusion criteria, and the control group of each group. The study groups will receive the same treatment and patient education for 6 weeks, while the control groups will receive only patient education.
- Being tested
- Progressive neck motor control exercise therapy, Patient education
- Keywords
- Temporomandibular Joint Dysfunction Syndrome, Pain, neck motor control exercise, posture, kinesiophobia, function
- Medical subject headings
- Temporomandibular Joint Dysfunction Syndrome, Pain, Kinesiophobia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Progressive neck motor control exercise therapyOther
The exercise programme will be conducted as a single session two days a week for 6 weeks. The sessions will always be conducted by the same physiotherapist. Each exercise session will consist of 10 minutes of warm-up exercises, 40 minutes of neck motor control exercises and 10 minutes of cool down exercises. Each exercise will be performed as 2 sets of 10 repetitions.
Patient educationOther
The content of this education consists of information about the disease and symptoms, chewing recommendations, dietary changes, parafunctional habits, activities to be avoided, posture recommendations.
| Study group | Role | What they receive |
|---|---|---|
| Myofascial | Experimental | Myofascial Temporomandibular Dysfunction Receives: Other: Progressive neck motor control exercise therapy; Other: Patient education |
| disc displacement with reduction | Experimental | Temporomandibular joint disc displacement with reduction Receives: Other: Progressive neck motor control exercise therapy; Other: Patient education |
| disc displacement without reduction | Experimental | Temporomandibular joint disc displacement without reduction Receives: Other: Progressive neck motor control exercise therapy; Other: Patient education |
| Myofascial2 | Other | Myofascial Temporomandibular Dysfunction Receives: Other: Patient education |
| disc displacement with reduction2 | Other | Temporomandibular joint disc displacement with reduction Receives: Other: Patient education |
| disc displacement without reduction2 | Other | Temporomandibular joint disc displacement without reduction Receives: Other: Patient education |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fonseca Anamnestic Index
Assessment of Temporomandibular Dysfunction Severity
Measured: 1st, sixth week, first mont
Numeric Pain Scale
Assessment of Pain, 0: No pain, 10: Maximum pain
Measured: 1st, sixth week, first mont
Pressure pain threshold
Assessment of Pressure pain threshold
Measured: 1st, sixth week, first mont
Range of motion
Assessment of Temporomandibular joint and neck range of motion
Measured: 1st, sixth week, first mont
Joint position error test
Assessment of Cervical proprioception
Measured: 1st, sixth week, first mont
Endurance
Assessment of Deep neck flexor endurance
Measured: 1st, sixth week, first mont
Photographic Posture Analysis
Assessment of head and neck posture
Measured: 1st, sixth week, first mont
Mandibular Function Impairment Questionnaire
Assessment of Mandibular Function
Measured: 1st, sixth week, first mont
Secondary outcomes (1)
Tampa kinesiophobia scale
Assessment of kinesiophobia for temporomandibular joint, 12 points: low kinesiophobia; 48 points:high kinesiophobia
Measured: 1st, sixth week, first mont
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Nov 2023
- Study start4 Nov 2024
- Primary completion30 May 2025 (estimated)
- Study completion30 Jun 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Temporomandibular Joint Dysfunction SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 75 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Karadeniz Technical University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nurhayat KORKMAZ, Karadeniz Technical University
- Investigators
- Nurhayat Korkmaz, PhDstudent, Principal investigator, Karadeniz Technical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06148818
- Sponsor's protocol ID
- 2023/15
- Status last verified
- Oct 2024
- First submitted
- 20 Nov 2023
- Last updated
- 29 Jan 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Korkmaz Ucuncu N, Yilmaz O, Korkmaz YT, Coskun G. An investigation of the effect of progressive neck motor control exercises on craniocervical pain, posture, function and kinesiophobia in different types of temporomandibular disorders: a randomised controlled study protocol. BMC Oral Health. 2026 Feb 5;26(1):285. doi: 10.1186/s12903-026-07775-z.
PubMed 41645126
Study at a glance
From the registry record, last updated by the sponsor on 29 Jan 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Effect of Progressive Neck Motor Control Exercises on Craniocervical Pain, Posture, Function and Kinesiophobia in Different Types of Temporomandibular Joint Dysfunction
- ClinicalTrials.gov ID
- NCT06148818
- Acronym / sponsor ID
- 2023/15
- Keywords
- Temporomandibular Joint Dysfunction Syndrome, Pain, neck motor control exercise, posture, kinesiophobia, function
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 75 participants (estimated)
- Lead sponsor
- Karadeniz Technical UniversityUniversity, hospital or other
- Study start
- 4 Nov 2024 (actual)
- Primary completion
- 30 May 2025 (estimated)
- Study completion
- 30 Jun 2025 (estimated)
- First posted
- 28 Nov 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The primary aim of this study was to investigate the effects of progressive neck motor control exercises on craniocervical pain, posture, function and kinesiophobia in different types of temporomandibular dysfunction. The secondary aim of the study was to examine the differences between the effects of progressive neck motor control exercises on different types of temporomandibular dysfunction.
Detailed description
In this randomised controlled study, the effects of progressive neck motor control exercise therapy on craniocervical pain, posture, function and kinesiophobia in individuals with different types of temporomandibular dysfunction (myofascial, disc displacement with reduction, disc displacement without reduction) and their differences with the control group will be compared. Participants diagnosed by a dentist according to three different types of temporomandibular dysfunction will be included in the study. Participants will be divided into groups by block randomisation method. A total of 6 groups will be included in the study, including participants with three different types of temporomandibular dysfunction who voluntarily agree to participate in the study and meet the inclusion criteria, and the control group of each group. The study groups will receive the same treatment and patient education for 6 weeks, while the control groups will receive only patient education.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 6
| Arm | Type | Receives |
|---|---|---|
| Myofascial | Experimental | Other: Progressive neck motor control exercise therapy, Other: Patient educationMyofascial Temporomandibular Dysfunction |
| disc displacement with reduction | Experimental | Other: Progressive neck motor control exercise therapy, Other: Patient educationTemporomandibular joint disc displacement with reduction |
| disc displacement without reduction | Experimental | Other: Progressive neck motor control exercise therapy, Other: Patient educationTemporomandibular joint disc displacement without reduction |
| Myofascial2 | Other | Other: Patient educationMyofascial Temporomandibular Dysfunction |
| disc displacement with reduction2 | Other | Other: Patient educationTemporomandibular joint disc displacement with reduction |
| disc displacement without reduction2 | Other | Other: Patient educationTemporomandibular joint disc displacement without reduction |
Who may qualify
- Ages
- 18 to 55 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- 18 to 55 years old,
- Temporomandibular joint-related complaints for at least 3 months,
- Temporomandibular dysfunction is diagnosed as a result of clinical and radiological evaluation by the dentist,
- Neck pain of 3 or more according to the numeric pain scale
Key exclusion criteria (10 listed)
- Cognitive problems,
- The one with the splint,
- Those who have used painkillers or muscle relaxants for temporomandibular dysfunction complaints in the last 1 week,
- With any systematic joint or muscle disease (e.g. fibromyalgia, rheumatoid arthritis),
- Those with serious systemic diseases,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Progressive neck motor control exercise therapyThe exercise programme will be conducted as a single session two days a week for 6 weeks. The sessions will always be conducted by the same physiotherapist. Each exercise session will consist of 10 minutes of warm-up exercises, 40 minutes of neck motor control exercises and 10 minutes of cool down exercises. Each exercise will be performed as 2 sets of 10 repetitions. | Other | Myofascial, disc displacement with reduction, disc displacement without reduction |
| Patient educationThe content of this education consists of information about the disease and symptoms, chewing recommendations, dietary changes, parafunctional habits, activities to be avoided, posture recommendations. | Other | Myofascial, Myofascial2, disc displacement with reduction, disc displacement with reduction2, disc displacement without reduction, disc displacement without reduction2 |
Primary outcome
Fonseca Anamnestic Index
Time frame: 1st, sixth week, first mont
Assessment of Temporomandibular Dysfunction Severity
Numeric Pain Scale
Time frame: 1st, sixth week, first mont
Assessment of Pain, 0: No pain, 10: Maximum pain
Pressure pain threshold
Time frame: 1st, sixth week, first mont
Assessment of Pressure pain threshold
Range of motion
Time frame: 1st, sixth week, first mont
Assessment of Temporomandibular joint and neck range of motion
Joint position error test
Time frame: 1st, sixth week, first mont
Assessment of Cervical proprioception
Endurance
Time frame: 1st, sixth week, first mont
Assessment of Deep neck flexor endurance
Photographic Posture Analysis
Time frame: 1st, sixth week, first mont
Assessment of head and neck posture
Mandibular Function Impairment Questionnaire
Time frame: 1st, sixth week, first mont
Assessment of Mandibular Function
1 secondary outcome
Tampa kinesiophobia scale
Time frame: 1st, sixth week, first mont
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jan 2025.
- Derived from this study: PubMed 41645126Korkmaz Ucuncu N, Yilmaz O, Korkmaz YT, Coskun G. An investigation of the effect of progressive neck motor control exercises on craniocervical pain, posture, function and kinesiophobia in different types of temporomandibular disorders: a randomised controlled study protocol. BMC Oral Health. 2026 Feb 5;26(1):285. doi: 10.1186/s12903-026-07775-z.
- Individual participant dataSharing planned: No
Related trials for Temporomandibular Joint Dysfunction Syndrome
Not yet recruiting
Comparing Dextrose Prolotherapy vs. Sodium Hyaluronic Acid Injections for Jaw Joint Internal Derangement
Temporomandibular Joint Internal Derangement, TMJ-ID
Recruiting
Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome
Myofacial Pain, Myofacial Pain Syndrome
Not yet recruitingObservational study
Comparison of Cervical and TMJ Parameters in Young Adults With and Without Text Neck Syndrome
Text Neck Syndrome, Temporomandibular Joint Disorders
Recruiting
Temporomandibular Joint (TMJ) Positioning Accuracy and Efficiency Using a Dental Compass.
Temporomandibular Joint Syndrome
Not yet recruiting
Comparison of Conventional,3D Printed and Novel Hybrid Stabilization Splints in the Management of Temporomandibular Joint Disorders
Temporomandibular Disorders (TMDs), Myofascial Pain - Dysfunction Syndrome of TMJ
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Nurhayat Korkmaz, PhDstudent principal investigator
Karadeniz Technical University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Patient education in people with Temporomandibular Joint Dysfunction Syndrome, run by Karadeniz Technical University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 29 Jan 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact nurhayat korkmaz, PhDstudent (+90538736 ext. 9062, krkmznrhyt@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Fonseca Anamnestic Index (time frame: 1st, sixth week, first mont). The study lists 8 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06148818, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jan 2025.