PreDiabetesNCT06208189
Is the Degree of Perceived Effort During Resistance Exercise Important for Improvements in Blood Glucose
A study testing High-effort session and Low-effort session in people with PreDiabetes and Type 2 Diabetes Mellitus, run by University of New Mexico at 1 site in United States.
Trial summary
The goal of this clinical trial is to compare the degree of effort during a resistance exercise session on blood glucose levels in individuals with prediabetes or type 2 diabetes mellitus. Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- PreDiabetes, Type 2 Diabetes Mellitus
- What is being tested?
- High-effort session and Low-effort session
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 15 participants
- Where
- 1 siteUnited States
- Study dates
- 12 Jun 2024to 30 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- age between 18 and 75 years;
- presence of prediabetes (fasting glycemia between 100 and 125 mg/dL or glycated hemoglobin [A1c] between 5.7 and 6.4%) or T2DM (fasting glycemia 126 mg/dL or above or A1c 6.5% or above).
Who cannot join
- renal failure,
- liver disease,
- uncontrolled hypertension (equal or greater than 160 mmHg systolic and/or equal or greater than 100 mmHg diastolic),
- history of severe cardiovascular problems,
- in case of oral hypoglycemic drugs usage, being on them for less than 6 months,
- inability to perform resistance exercise,
Show all 11Show fewer
- being pregnant or trying to become pregnant during the course of the study,
- use of oral contraceptives,
- prisoners,
- persons requiring a legally authorized representative,
- non-English speakers.
Trial locations and contacts
1 site in 1 country.
United States1 site
UNM Exercise Physiology Lab
Albuquerque, New Mexico, 87131-0001
About this study
Official title: The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals With Prediabetes or Type 2 Diabetes Mellitus: a Randomized-controlled Trial
The goal of this clinical trial is to compare the degree of effort during a resistance exercise session on blood glucose levels in individuals with prediabetes or type 2 diabetes mellitus. The main questions it aims to answer are:
- Do individuals with prediabetes or type 2 diabetes mellitus need to perform resistance exercise with a high degree of effort for their blood glucose to improve?
- How do they feel (their enjoyment, discomfort) after the sessions with different degrees of effort?
Read more
Participants will perform 3 situations separated by at least 4 days, after being familiarized with all exercises and procedures:
- One control day, when they will not exercise;
- A high-effort resistance exercise session;
- A low-effort resistance exercise session Researchers will measure blood glucose levels and psychological responses after these situations to see if the effort was important for the improvement of their blood glucose and how effort affected the way they felt after each situation.
- Conditions
- PreDiabetes, Type 2 Diabetes Mellitus
- Being tested
- High-effort session, Low-effort session, Control
- Keywords
- strength exercise, degree of effort, glycemic control, continuous glucose monitoring, prediabetes, type 2 diabetes mellitus
- Medical subject headings
- Prediabetic State, Diabetes Mellitus, Type 2
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
High-effort sessionBehavioural
Participants will perform 3 sets per exercise (total of 21 sets) with as many repetitions they can each set. We anticipate participants will perform ~10 repetitions per set in this session, with a total tempo of ~2.5 seconds per rep, averaging ~25 seconds per set. Resting period between exercises and sets will be 120 seconds. This will lead to a total session time of ~50 min. Their glycemic control will be evaluated during the following ~48 hours.
Low-effort sessionBehavioural
Participants will perform 6 sets per exercise (total of 42 sets) but perform half of the anticipated number of repetitions of the HIGH session (i.e., 5 reps). Repetition tempo at ~2.5 seconds will result in ~12.5 seconds per set. Resting period between exercises and sets will be 60 seconds. This prescription will also lead to a total session time of ~50 min. Thus, both the HIGH and LOW session will have similar total volume-load and session density, but differ in perceived effort after each set. Their glycemic control will be evaluated during the following ~48 hours.
ControlBehavioural
The control session all procedures will be identical to the HIGH session, with the exception of performing the resistance exercises. However, to simulate all other procedures participants will follow all instructions, be positioned on the equipment for the same amount of time as the HIGH session, but will not perform any repetition. Interval between fake sets and exercises will be 120 seconds. Their glycemic control will be evaluated during the following ~48 hours.
| Study group | Role | What they receive |
|---|---|---|
| high-effort session | Experimental | Participants will perform sets with as many repetitions they can each set. Receives: Behavioral: High-effort session |
| low-effort session | Experimental | Participants will perform sets with half of the anticipated number of repetitions of the high-effort session. Receives: Behavioral: Low-effort session |
| Control session | Sham comparator | The control session all procedures will be identical to the high-effort session. Receives: Behavioral: Control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Glucose concentration
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Measured: For 48 hours during each situation (arm) of the study
Glucose concentration
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Measured: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study
Glucose concentration
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Measured: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study
Glucose concentration
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Measured: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study
Glucose concentration
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Measured: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study
Time in range
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Measured: For 48 hours during each situation (arm) of the study
Time in range
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Measured: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study
Time in range
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Measured: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study
Time in range
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Measured: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study
Time in range
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Measured: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study
Prevalence of hyperglycemia
Time of glucose concentrations >180 mg/dL (measured in minutes)
Measured: For 48 hours during each situation (arm) of the study
Prevalence of hyperglycemia
Time of glucose concentrations >180 mg/dL (measured in minutes)
Measured: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study
Prevalence of hyperglycemia
Time of glucose concentrations >180 mg/dL (measured in minutes)
Measured: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study
Prevalence of hyperglycemia
Time of glucose concentrations >180 mg/dL (measured in minutes)
Measured: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study
Prevalence of hyperglycemia
Time of glucose concentrations >180 mg/dL (measured in minutes)
Measured: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study
Prevalence of hypoglycemia
Time of glucose concentrations <70 mg/dL (measured in minutes)
Measured: For 48 hours during each situation (arm) of the study
Prevalence of hypoglycemia
Time of glucose concentrations <70 mg/dL (measured in minutes)
Measured: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study
Prevalence of hypoglycemia
Time of glucose concentrations <70 mg/dL (measured in minutes)
Measured: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study
Prevalence of hypoglycemia
Time of glucose concentrations <70 mg/dL (measured in minutes)
Measured: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study
Prevalence of hypoglycemia
Time of glucose concentrations <70 mg/dL (measured in minutes)
Measured: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study
Secondary outcomes (6)
Resistance Training Intensity by the Omni Perceived Exertion Scale
Discrete scale from 0 to 10, where higher values mean more perceived exertion.
Measured: After each set of each exercise performed.
Feeling scale
Discrete scale from -5 to +5, where higher values mean more positive feelings.
Measured: Before and immediately after the resistance exercise sessions.
Physical Activity Enjoyment Scale
Scale composed of 18 items, with scores from 1 to 7 each (total score from 18 to 126). After analysis, higher scores mean higher enjoyment.
Measured: Immediately after the resistance exercise sessions.
Self-efficacy scale
Scale composed of 8 questions, with discrete options from 0 to 100%. Higher scores mean higher self-efficacy.
Measured: Immediately after the resistance exercise sessions.
Rating of Discomfort scale
Discrete scale from 0 to 100, where higher scores mean more discomfort.
Measured: Before and 5 minutes after the resistance exercise sessions.
Session rating of perceived exertion
Discrete scale from 0 to 10, where higher values mean more perceived exertion.
Measured: 5 minutes after the resistance exercise sessions.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jan 2024
- Study start12 Jun 2024
- Primary completion30 Oct 2026 (estimated)
- Study completion30 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for PreDiabetesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Model description
- Randomized controlled, crossover, 3-way, clinical trial, following the SPIRIT and the TIDieR guidelines. After being considered eligible and agreeing to participate, participants will undergo anthropometrics assessment, familiarization sessions, and strength assessment before randomly carrying out 3 experimental (2 exercise and one control) periods, each composed of a total of \~48 hours, separated by at least 4 days. During the experimental periods diet will be strictly controlled and provided to the participants. Glycemic control will be assessed by a continuous glucose monitoring system throughout the experimental periods. The exercise sessions will be identical regarding total volume-load and session density, but proximity to failure in each set will be manipulated so effort will be different between the sessions. The control session will be identical in all procedures as the exercise sessions except that participants will remain sedentary.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 15 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of New Mexico
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Flavio de Castro Magalhaes, University of New Mexico
- Investigators
- Flavio De Castro Magalhaes, PhD, Principal investigator, Assistant Professor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06208189
- Sponsor's protocol ID
- 2310089095
- Status last verified
- Sep 2026
- First submitted
- 28 Dec 2023
- Last updated
- 4 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: For sharing the data generated we will use the Open Science Framework (OSF) platform. Before data sharing, all personal identifiers will be stripped from the data. Specifically, any direct identifiers (e.g., name, email addresses, phone and cell phone numbers), date identifiers (e.g., birthday, date of disease diagnosis, dates patients participated in data collection), location identifiers (e.g., personal or professional addresses, zip codes), links to external datasets identifiers (e.g., social media accounts) will be removed. Furthermore, participants will be represented by an ID string generated randomly (https://www.random.org/strings/), and their data will be inserted in the files in a random order, not associated with the order they were enrolled. Thus, data will be entirely de-identified before sharing, in order to protect sensitive personal information and privacy.
Publications
Ramirez M, Gebauer M, Mermier C, Little JP, Lin L, Palley G, Hsiao YY, Mota Alvidrez RI, Mang ZA, Amorim FT, Tricoli V, De Castro Magalhaes F. The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals Living With Prediabetes or Type 2 Diabetes: Protocol for a Crossover Randomized Controlled Trial. JMIR Res Protoc. 2024 Nov 5;13:e63598. doi: 10.2196/63598.
PubMed 39499920
Study at a glance
From the registry record, last updated by the sponsor on 4 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals With Prediabetes or Type 2 Diabetes Mellitus: a Randomized-controlled Trial
- ClinicalTrials.gov ID
- NCT06208189
- Acronym / sponsor ID
- 2310089095
- Conditions
- PreDiabetes, Type 2 Diabetes Mellitus
- Keywords
- strength exercise, degree of effort, glycemic control, continuous glucose monitoring, prediabetes, type 2 diabetes mellitus
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 15 participants (estimated)
- Lead sponsor
- University of New MexicoUniversity, hospital or other
- Study start
- 12 Jun 2024 (actual)
- Primary completion
- 30 Oct 2026 (estimated)
- Study completion
- 30 Oct 2026 (estimated)
- First posted
- 17 Jan 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to compare the degree of effort during a resistance exercise session on blood glucose levels in individuals with prediabetes or type 2 diabetes mellitus. The main questions it aims to answer are:
- Do individuals with prediabetes or type 2 diabetes mellitus need to perform resistance exercise with a high degree of effort for their blood glucose to improve?
- How do they feel (their enjoyment, discomfort) after the sessions with different degrees of effort?
Participants will perform 3 situations separated by at least 4 days, after being familiarized with all exercises and procedures:
- One control day, when they will not exercise;
- A high-effort resistance exercise session;
- A low-effort resistance exercise session Researchers will measure blood glucose levels and psychological responses after these situations to see if the effort was important for the improvement of their blood glucose and how effort affected the way they felt after each situation.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
- Model description
- Randomized controlled, crossover, 3-way, clinical trial, following the SPIRIT and the TIDieR guidelines. After being considered eligible and agreeing to participate, participants will undergo anthropometrics assessment, familiarization sessions, and strength assessment before randomly carrying out 3 experimental (2 exercise and one control) periods, each composed of a total of ~48 hours, separated by at least 4 days. During the experimental periods diet will be strictly controlled and provided to the participants. Glycemic control will be assessed by a continuous glucose monitoring system throughout the experimental periods. The exercise sessions will be identical regarding total volume-load and session density, but proximity to failure in each set will be manipulated so effort will be different between the sessions. The control session will be identical in all procedures as the exercise sessions except that participants will remain sedentary.
| Arm | Type | Receives |
|---|---|---|
| high-effort session | Experimental | Behavioral: High-effort sessionParticipants will perform sets with as many repetitions they can each set. |
| low-effort session | Experimental | Behavioral: Low-effort sessionParticipants will perform sets with half of the anticipated number of repetitions of the high-effort session. |
| Control session | Sham comparator | Behavioral: ControlThe control session all procedures will be identical to the high-effort session. |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- age between 18 and 75 years;
- presence of prediabetes (fasting glycemia between 100 and 125 mg/dL or glycated hemoglobin [A1c] between 5.7 and 6.4%) or T2DM (fasting glycemia 126 mg/dL or above or A1c 6.5% or above).
Key exclusion criteria (11 listed)
- renal failure,
- liver disease,
- uncontrolled hypertension (equal or greater than 160 mmHg systolic and/or equal or greater than 100 mmHg diastolic),
- history of severe cardiovascular problems,
- in case of oral hypoglycemic drugs usage, being on them for less than 6 months,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| High-effort sessionParticipants will perform 3 sets per exercise (total of 21 sets) with as many repetitions they can each set. We anticipate participants will perform ~10 repetitions per set in this session, with a total tempo of ~2.5 seconds per rep, averaging ~25 seconds per set. Resting period between exercises and sets will be 120 seconds. This will lead to a total session time of ~50 min. Their glycemic control will be evaluated during the following ~48 hours. | Behavioural | high-effort session |
| Low-effort sessionParticipants will perform 6 sets per exercise (total of 42 sets) but perform half of the anticipated number of repetitions of the HIGH session (i.e., 5 reps). Repetition tempo at ~2.5 seconds will result in ~12.5 seconds per set. Resting period between exercises and sets will be 60 seconds. This prescription will also lead to a total session time of ~50 min. Thus, both the HIGH and LOW session will have similar total volume-load and session density, but differ in perceived effort after each set. Their glycemic control will be evaluated during the following ~48 hours. | Behavioural | low-effort session |
| ControlThe control session all procedures will be identical to the HIGH session, with the exception of performing the resistance exercises. However, to simulate all other procedures participants will follow all instructions, be positioned on the equipment for the same amount of time as the HIGH session, but will not perform any repetition. Interval between fake sets and exercises will be 120 seconds. Their glycemic control will be evaluated during the following ~48 hours. | Behavioural | Control session |
Primary outcome
Glucose concentration
Time frame: For 48 hours during each situation (arm) of the study
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Glucose concentration
Time frame: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Glucose concentration
Time frame: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Glucose concentration
Time frame: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Glucose concentration
Time frame: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study
Average glucose concentration (measured in milligrams per deciliter of blood, with a continuous glucose monitoring device)
Time in range
Time frame: For 48 hours during each situation (arm) of the study
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Time in range
Time frame: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Time in range
Time frame: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Time in range
Time frame: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Time in range
Time frame: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study
Time of glucose concentration between 70 and 180 mg/dL (measured in minutes)
Prevalence of hyperglycemia
Time frame: For 48 hours during each situation (arm) of the study
Time of glucose concentrations >180 mg/dL (measured in minutes)
Prevalence of hyperglycemia
Time frame: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study
Time of glucose concentrations >180 mg/dL (measured in minutes)
Prevalence of hyperglycemia
Time frame: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study
Time of glucose concentrations >180 mg/dL (measured in minutes)
Prevalence of hyperglycemia
Time frame: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study
Time of glucose concentrations >180 mg/dL (measured in minutes)
Prevalence of hyperglycemia
Time frame: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study
Time of glucose concentrations >180 mg/dL (measured in minutes)
Prevalence of hypoglycemia
Time frame: For 48 hours during each situation (arm) of the study
Time of glucose concentrations <70 mg/dL (measured in minutes)
Prevalence of hypoglycemia
Time frame: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study
Time of glucose concentrations <70 mg/dL (measured in minutes)
Prevalence of hypoglycemia
Time frame: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study
Time of glucose concentrations <70 mg/dL (measured in minutes)
Prevalence of hypoglycemia
Time frame: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study
Time of glucose concentrations <70 mg/dL (measured in minutes)
Prevalence of hypoglycemia
Time frame: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study
Time of glucose concentrations <70 mg/dL (measured in minutes)
6 secondary outcomes
Resistance Training Intensity by the Omni Perceived Exertion Scale
Time frame: After each set of each exercise performed.
Feeling scale
Time frame: Before and immediately after the resistance exercise sessions.
Physical Activity Enjoyment Scale
Time frame: Immediately after the resistance exercise sessions.
Self-efficacy scale
Time frame: Immediately after the resistance exercise sessions.
Rating of Discomfort scale
Time frame: Before and 5 minutes after the resistance exercise sessions.
Session rating of perceived exertion
Time frame: 5 minutes after the resistance exercise sessions.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Sep 2026.
- Derived from this study: PubMed 39499920Ramirez M, Gebauer M, Mermier C, Little JP, Lin L, Palley G, Hsiao YY, Mota Alvidrez RI, Mang ZA, Amorim FT, Tricoli V, De Castro Magalhaes F. The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals Living With Prediabetes or Type 2 Diabetes: Protocol for a Crossover Randomized Controlled Trial. JMIR Res Protoc. 2024 Nov 5;13:e63598. doi: 10.2196/63598.
- Individual participant dataSharing planned: Yes. For sharing the data generated we will use the Open Science Framework (OSF) platform. Before data sharing, all personal identifiers will be stripped from the data. Specifically, any direct identifiers (e.g., name, email addresses, phone and cell phone numbers), date identifiers (e.g., birthday, date of disease diagnosis, dates patients participated in data collection), location identifiers (e.g., personal or professional addresses, zip codes), links to external datasets identifiers (e.g., social media accounts) will be removed. Furthermore, participants will be represented by an ID string generated randomly (https://www.random.org/strings/), and their data will be inserted in the files in a random order, not associated with the order they were enrolled. Thus, data will be entirely de-identified before sharing, in order to protect sensitive personal information and privacy.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Flavio De Castro Magalhaes, PhD principal investigator
Assistant Professor
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing High-effort session and Low-effort session in people with PreDiabetes and Type 2 Diabetes Mellitus, run by University of New Mexico at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 4 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Glucose concentration (time frame: For 48 hours during each situation (arm) of the study). The study lists 20 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06208189, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Sep 2026.