Neuropathic PainNCT06216717
Study of the Location of Motor Cortical Stimulation Electrodes in Chronic Neuropathic Refractory Patients
An observational study of Neuropathic Pain, run by Centre Hospitalier Universitaire de Nice at 1 site in France.
Trial summary
Cortical stimulation has been used since 1991 to treat neuropathic pain. However, the underlying mechanisms are still incompletely understood and under-studied. In this protocol, the investigators aim to study the myeloarchitectonic and functional characteristics of areas activated by cortical epidural electrodes and… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Neuropathic Pain
- How many people
- 100 participants
- Where
- 1 siteFrance
- Study dates
- 13 Nov 2023to 25 Jun 2027
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Adult, Older adult
Study population: adults who were implanted with a motor cortical stimulation system for treatment of chronic neuropathic refractory pain between 2003-2023
Who may be able to join
- adults
- patient implanted with a motor cortical stimulation system for chronic neuropathic refractory pain,
- patient with available postoperative scanner
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
CHU NICE
Nice, Alpes Maritimes
petru isan, 064219135 ext. + 33, isan.p@chu-nice.fr
cynthia caillon, 0492034589 ext. +33, caillon.@chu-nice.fr
About this study
Cortical stimulation has been used since 1991 to treat neuropathic pain. However, the underlying mechanisms are still incompletely understood and under-studied. In this protocol, the investigators aim to study the myeloarchitectonic and functional characteristics of areas activated by cortical epidural electrodes and to determine their relation to therapy response in chronic neuropathic refractory pain patients.
- Conditions
- Neuropathic Pain
- Medical subject headings
- Neuralgia
What is being measured
The primary outcome is the main question the study is designed to answer.
Pourcentage of pain relief
percentage of pain relief for different stimulated areas
Measured: 1 year
Secondary outcomes (1)
location of leads on the postoperative imaging
location of leads on the postoperative imaging
Measured: 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jan 2024
- Study start13 Nov 2023
- Primary completion16 Mar 2025
- Study completion25 Jun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Neuropathic PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire de Nice
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Petru ISAN, Principal investigator, Centre Hospitalier Universitaire de Nice
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06216717
- Sponsor's protocol ID
- 24Neurochir01
- Status last verified
- Jun 2026
- First submitted
- 11 Jan 2024
- Last updated
- 29 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No