HealthyVIBRANIRSNCT06218563
Study of Cerebral Activation by fNIRS During Vibration-induced Illusion of Movement in Healthy and Stroke Participants.
A study testing vibration-induced illusion of movement in people with Healthy and Stroke, Acute, run by Centre Hospitalier Régional d'Orléans at 1 site in France.
Trial summary
The purpose of this study is to investigate the cerebral activation of healthy and stroke participants in 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block. The frequency of the vibration being 80 Hz. Read more about this study
- Who is it for?
- Ages 18 to 85 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy, Stroke, Acute
- What is being tested?
- vibration-induced illusion of movement
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteFrance
- Study dates
- 10 Jan 2024to 25 Jun 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 85 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- 18-85 years old
- Able to sign a consent form
- Sufficient command of the French language to understand instructions
- Affiliated to a social security scheme
- Healthy participants:
- Right handed
Show all 13Show fewer
- No neurological disease or motor deficit
- Stroke participants:
- Stroke volunteers in acute phase (before day 14 post-stroke)
- Not aphasic
- Able to maintain sitting position without difficulty
- Deficit moteur
- Able to sign a consent form
Who cannot join
- Person under tutorship or curatorship
- Known allergy to of the fNIRS cap components: neoprene
- No vibrations feeling on the deficient side
- Vigilance-modifying drugs (high-dose psychotropics, antispastic drugs)
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Vibration-induced Movement Illusion Causes Cerebral Haemodynamic Changes: A fNIRS Study.
The purpose of this study is to investigate the cerebral activation of healthy and stroke participants in 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block. The frequency of the vibration being 80 Hz.
Healthy participants:
- Right arm, eyes opened
- Right arm, eyes closed
- Left arm, eyes opened
- Left arm, eyes closed
Stroke participants:
- Deficient side, eyes opened
- Deficient side, eyes closed
The aim is to compare the subjective sensation of movement score and cerebral activations of healthy/stroke participants depending on the condition.
Read the detailed description
Perceived sensations of limb and movements (kinesthesia) allow us to situate ourselves without visual feedback and not dedicate all of our attention to everyday tasks such as walking or taking and holding an object. These perceived conscious sensations come from receptors called proprioceptors which are located in the skin, joints and muscles. When a limb is moving and a muscle is stretched, the main sensation of limb stretching comes from the stimulation of a proprioceptor called the muscle spindle, more specifically from its primary ending called the 1a fibber. Artificially, 1a fibbers can be (optimally) stimulated by vibration of the muscle around 80 Hz. When stimulating 1a fibbers of the triceps, a signal of stretching is produced and an illusion of flexion can be felt as long as their no other contrary feedback involved such as vibration of the antagonist muscle or visual feedback of the immobile limb as it provides a more reliable information to the brain. As of now, neural correlates to muscle spindle vibration and illusion of movement have not been fully characterize in healthy participants and are not known in stroke participants.
To investigate the effect of vibration-induced illusion of movement on cerebral activations in healthy and stroke participants, the investigators propose to use an innovative tool of neuroimaging, the functional near infrared spectroscopy (fNIRS).
fNIRS allows to investigate cortical cerebral activations by measuring cerebral haemodynamic variations. Indeed, just like fMRI, it relies on the haemodynamic response function (HRF) caused by neurovascular coupling. Its portability and non-invasiveness make it a great tool to study brain activations in a more ecological environment (in a standing or sitting position for example).
This research aims to study and compare the subjective sensation of movement and the cortical cerebral areas involved in muscle spindle vibration and illusion of movement in healthy and stroke participants.
The protocol consists of 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement in healthy and stroke participants respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block:
Healthy participants, 2 times each (24 vibrations):
- Right arm, eyes opened (no-illusion condition; RO)
- Right arm, eyes closed (illusion condition; RC)
- Left arm, eyes opened (no-illusion condition; LO)
- Left arm, eyes closed (illusion condition; LC)
Stroke participants, 2 times each (12 vibrations):
- Deficient side, eyes opened (no-illusion condition; DO)
- Deficient side, eyes closed (illusion condition; DC)
Conditions order is pseudorandomized, participants can start by the left or the right arm with eyes opened or closed. When starting with either the left or right arm, all conditions are completed before moving on to the other arm (for healthy participants). In total, the number of participants starting with right or left vibration should be the same.
The fNIRS devices that will be used are the Brite MKII and Brite MKIII (Artinis Medical system, Netherlands).
The vibration tool that will be used is a vibrator from VibraMoov. The subjective sensation of movement will be analyzed using the Standardized Kinesthetic Illusion Procedure (SKIP) scale. Participants will have to report their sensation of movement after each condition (3 vibrations block) from 0 to 3, 0 being no sensation of movement and 3 being a clear and precise sensation of movement. Participants will also have to describe the direction of movement, a score of 1 will be attributed if the movement described correspond to the one expected and a score of 0 will be attributed for every other movements.
- Conditions
- Healthy, Stroke, Acute
- Being tested
- vibration-induced illusion of movement
- Keywords
- Vibration, Illusion of movement, Functional Near Infrared Spectroscopy
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
vibration-induced illusion of movementOther
Conditions order is pseudorandomized, participants can start by the left or the right arm with eyes opened or closed. When starting with either the left or right arm, all conditions are completed before moving on to the other arm (for healthy participants). In total, the number of participants starting with right or left vibration should be the same.
| Study group | Role | What they receive |
|---|---|---|
| vibration-induced illusion of movement | Experimental | The protocol consists of 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement in healthy and stroke participants respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block:
Healthy participants, 2 times each (24 vibrations):
* Right arm, eyes opened (no-illusion condition; RO)
* Right arm, eyes closed (illusion condition; RC)
* Left arm, eyes opened (no-illusion condition; LO)
* Left arm, eyes closed (illusion condition; LC)
Stroke participants, 2 times each (12 vibrations):
* Deficient side, eyes opened (no-illusion condition; DO)
* Deficient side, eyes closed (illusion condition; DC) Receives: Other: vibration-induced illusion of movement |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mean change in the concentration of oxyhemoglobin during the task
The HbO2 signals are considered as indicators of the hemodynamic response.
Measured: Day 0
Mean change in the concentration of deoxyhemoglobin during the task
The HbR signals are considered as indicators of the hemodynamic response.
Measured: Day 0
Secondary outcomes (1)
SKIP scale
The subjective sensation of movement will be analyzed using the Standardized Kinesthetic Illusion Procedure (SKIP) scale. Participants will have to report their sensation of movement after each condition (3 vibrations block) from 0 to 3, 0 being no sensation of movement and 3 being a clear and precise sensation of movement. Participants will also have to describe the direction of movement, a score of 1 will be attributed if the movement described correspond to the one expected and a score of 0 will be attributed for every other movements.
Measured: Day 0
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jan 2024
- Study start10 Jan 2024
- Primary completion25 Jun 2025
- Study completion25 Jun 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (15)Papers the sponsor has linked to this study.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- The protocol consists of 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement in healthy and stroke participants respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block. Conditions order is pseudorandomized, participants can start by the left or the right arm with eyes opened or closed. When starting with either the left or right arm, all conditions are completed before moving on to the other arm (for healthy participants). In total, the number of participants starting with right or left vibration should be the same.
- Masking
- None (open label)
- Enrolment
- 90 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Régional d'Orléans
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Canan OZSANCAK, Dr, Principal investigator, CHU d'Orléans
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06218563
- Sponsor's protocol ID
- CHRO-2023-05
- Acronym
- VIBRANIRS
- Status last verified
- Jul 2025
- First submitted
- 12 Jan 2024
- Last updated
- 8 Jul 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Adamo DE, Scotland S, Martin BJ. Upper limb kinesthetic asymmetries: gender and handedness effects. Neurosci Lett. 2012 May 16;516(2):188-92. doi: 10.1016/j.neulet.2012.03.077. Epub 2012 Apr 3.
PubMed 22490887Chancel M, Landelle C, Blanchard C, Felician O, Guerraz M, Kavounoudias A. Hand movement illusions show changes in sensory reliance and preservation of multisensory integration with age for kinaesthesia. Neuropsychologia. 2018 Oct;119:45-58. doi: 10.1016/j.neuropsychologia.2018.07.027. Epub 2018 Jul 29.
PubMed 30063911Collins DF, Refshauge KM, Todd G, Gandevia SC. Cutaneous receptors contribute to kinesthesia at the index finger, elbow, and knee. J Neurophysiol. 2005 Sep;94(3):1699-706. doi: 10.1152/jn.00191.2005. Epub 2005 May 25.
PubMed 15917323Desmurget M, Reilly KT, Richard N, Szathmari A, Mottolese C, Sirigu A. Movement intention after parietal cortex stimulation in humans. Science. 2009 May 8;324(5928):811-3. doi: 10.1126/science.1169896.
PubMed 19423830Gilhodes JC, Roll JP, Tardy-Gervet MF. Perceptual and motor effects of agonist-antagonist muscle vibration in man. Exp Brain Res. 1986;61(2):395-402. doi: 10.1007/BF00239528.
PubMed 3948946Guerraz M, Provost S, Narison R, Brugnon A, Virolle S, Bresciani JP. Integration of visual and proprioceptive afferents in kinesthesia. Neuroscience. 2012 Oct 25;223:258-68. doi: 10.1016/j.neuroscience.2012.07.059. Epub 2012 Aug 3.
PubMed 22864182Hagura N, Takei T, Hirose S, Aramaki Y, Matsumura M, Sadato N, Naito E. Activity in the posterior parietal cortex mediates visual dominance over kinesthesia. J Neurosci. 2007 Jun 27;27(26):7047-53. doi: 10.1523/JNEUROSCI.0970-07.2007.
PubMed 17596454Imai R, Hayashida K, Nakano H, Morioka S. Brain Activity Associated with the Illusion of Motion Evoked by Different Vibration Stimulation Devices: An fNIRS Study. J Phys Ther Sci. 2014 Jul;26(7):1115-9. doi: 10.1589/jpts.26.1115. Epub 2014 Jul 30.
PubMed 25140108Kodama T, Nakano H, Ohsugi H, Murata S. Effects of vibratory stimulation-induced kinesthetic illusions on the neural activities of patients with stroke. J Phys Ther Sci. 2016 Jan;28(2):419-25. doi: 10.1589/jpts.28.419. Epub 2016 Feb 29.
PubMed 27065525Proske U, Gandevia SC. The proprioceptive senses: their roles in signaling body shape, body position and movement, and muscle force. Physiol Rev. 2012 Oct;92(4):1651-97. doi: 10.1152/physrev.00048.2011.
PubMed 23073629Romaiguere P, Anton JL, Roth M, Casini L, Roll JP. Motor and parietal cortical areas both underlie kinaesthesia. Brain Res Cogn Brain Res. 2003 Mar;16(1):74-82. doi: 10.1016/s0926-6410(02)00221-5.
PubMed 12589891Skinner HB, Barrack RL, Cook SD. Age-related decline in proprioception. Clin Orthop Relat Res. 1984 Apr;(184):208-11.
PubMed 6705349Tidoni E, Fusco G, Leonardis D, Frisoli A, Bergamasco M, Aglioti SM. Illusory movements induced by tendon vibration in right- and left-handed people. Exp Brain Res. 2015 Feb;233(2):375-83. doi: 10.1007/s00221-014-4121-8. Epub 2014 Oct 8.
PubMed 25294499Leger B, Auzou P, Fourdrinoy E, Sarrazin M, Celot S, Gay C, de Dieuleveult B, Cohen C, Ozsancak C, Perrey S. Cortical neuromodulation by vibration-induced illusion of movement is observed in older individuals, but not in individuals with acute stroke: a cross-sectional fNIRS study. J Neuroeng Rehabil. 2026 Aug 31;23(1):254. doi: 10.1186/s12984-026-02129-w.
PubMed 42675504Leger B, Auzou P, Fourdrinoy E, Sarrazin M, Celot S, Gay C, de Dieuleveult B, Cohen C, Perrey S, Ozsancak C. Vibration-induced illusion of movement is hindered by acute stroke but mostly by aging: a cross-sectional study. Aging Clin Exp Res. 2025 Dec 1;38(1):20. doi: 10.1007/s40520-025-03247-6.
PubMed 41324779
Study at a glance
From the registry record, last updated by the sponsor on 8 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Vibration-induced Movement Illusion Causes Cerebral Haemodynamic Changes: A fNIRS Study.
- ClinicalTrials.gov ID
- NCT06218563
- Acronym / sponsor ID
- VIBRANIRS / CHRO-2023-05
- Conditions
- Healthy, Stroke, Acute
- Keywords
- Vibration, Illusion of movement, Functional Near Infrared Spectroscopy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 90 participants (actual)
- Lead sponsor
- Centre Hospitalier Régional d'OrléansUniversity, hospital or other
- Study start
- 10 Jan 2024 (actual)
- Primary completion
- 25 Jun 2025 (actual)
- Study completion
- 25 Jun 2025 (actual)
- First posted
- 23 Jan 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to investigate the cerebral activation of healthy and stroke participants in 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block. The frequency of the vibration being 80 Hz.
Healthy participants:
- Right arm, eyes opened
- Right arm, eyes closed
- Left arm, eyes opened
- Left arm, eyes closed
Stroke participants:
- Deficient side, eyes opened
- Deficient side, eyes closed
The aim is to compare the subjective sensation of movement score and cerebral activations of healthy/stroke participants depending on the condition.
Detailed description
Perceived sensations of limb and movements (kinesthesia) allow us to situate ourselves without visual feedback and not dedicate all of our attention to everyday tasks such as walking or taking and holding an object. These perceived conscious sensations come from receptors called proprioceptors which are located in the skin, joints and muscles. When a limb is moving and a muscle is stretched, the main sensation of limb stretching comes from the stimulation of a proprioceptor called the muscle spindle, more specifically from its primary ending called the 1a fibber. Artificially, 1a fibbers can be (optimally) stimulated by vibration of the muscle around 80 Hz. When stimulating 1a fibbers of the triceps, a signal of stretching is produced and an illusion of flexion can be felt as long as their no other contrary feedback involved such as vibration of the antagonist muscle or visual feedback of the immobile limb as it provides a more reliable information to the brain. As of now, neural correlates to muscle spindle vibration and illusion of movement have not been fully characterize in healthy participants and are not known in stroke participants.
To investigate the effect of vibration-induced illusion of movement on cerebral activations in healthy and stroke participants, the investigators propose to use an innovative tool of neuroimaging, the functional near infrared spectroscopy (fNIRS).
fNIRS allows to investigate cortical cerebral activations by measuring cerebral haemodynamic variations. Indeed, just like fMRI, it relies on the haemodynamic response function (HRF) caused by neurovascular coupling. Its portability and non-invasiveness make it a great tool to study brain activations in a more ecological environment (in a standing or sitting position for example).
This research aims to study and compare the subjective sensation of movement and the cortical cerebral areas involved in muscle spindle vibration and illusion of movement in healthy and stroke participants.
The protocol consists of 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement in healthy and stroke participants respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block:
Healthy participants, 2 times each (24 vibrations):
- Right arm, eyes opened (no-illusion condition; RO)
- Right arm, eyes closed (illusion condition; RC)
- Left arm, eyes opened (no-illusion condition; LO)
- Left arm, eyes closed (illusion condition; LC)
Stroke participants, 2 times each (12 vibrations):
- Deficient side, eyes opened (no-illusion condition; DO)
- Deficient side, eyes closed (illusion condition; DC)
Conditions order is pseudorandomized, participants can start by the left or the right arm with eyes opened or closed. When starting with either the left or right arm, all conditions are completed before moving on to the other arm (for healthy participants). In total, the number of participants starting with right or left vibration should be the same.
The fNIRS devices that will be used are the Brite MKII and Brite MKIII (Artinis Medical system, Netherlands).
The vibration tool that will be used is a vibrator from VibraMoov. The subjective sensation of movement will be analyzed using the Standardized Kinesthetic Illusion Procedure (SKIP) scale. Participants will have to report their sensation of movement after each condition (3 vibrations block) from 0 to 3, 0 being no sensation of movement and 3 being a clear and precise sensation of movement. Participants will also have to describe the direction of movement, a score of 1 will be attributed if the movement described correspond to the one expected and a score of 0 will be attributed for every other movements.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- The protocol consists of 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement in healthy and stroke participants respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block. Conditions order is pseudorandomized, participants can start by the left or the right arm with eyes opened or closed. When starting with either the left or right arm, all conditions are completed before moving on to the other arm (for healthy participants). In total, the number of participants starting with right or left vibration should be the same.
| Arm | Type | Receives |
|---|---|---|
| vibration-induced illusion of movement | Experimental | Other: vibration-induced illusion of movementThe protocol consists of 4 or 2 different conditions (repeated 2 times) of vibration-induced illusion of movement in healthy and stroke participants respectively, resulting in 8 or 4 vibration blocks with 3 vibrations per block: Healthy participants, 2 times each (24 vibrations): * Right arm, eyes opened (no-illusion condition; RO) * Right arm, eyes closed (illusion condition; RC) * Left arm, eyes opened (no-illusion condition; LO) * Left arm, eyes closed (illusion condition; LC) Stroke participants, 2 times each (12 vibrations): * Deficient side, eyes opened (no-illusion condition; DO) * Deficient side, eyes closed (illusion condition; DC) |
Who may qualify
- Ages
- 18 to 85 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (13 listed)
- 18-85 years old
- Able to sign a consent form
- Sufficient command of the French language to understand instructions
- Affiliated to a social security scheme
- Right handed
Key exclusion criteria (4 listed)
- Person under tutorship or curatorship
- Known allergy to of the fNIRS cap components: neoprene
- No vibrations feeling on the deficient side
- Vigilance-modifying drugs (high-dose psychotropics, antispastic drugs)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| vibration-induced illusion of movementConditions order is pseudorandomized, participants can start by the left or the right arm with eyes opened or closed. When starting with either the left or right arm, all conditions are completed before moving on to the other arm (for healthy participants). In total, the number of participants starting with right or left vibration should be the same. | Other | vibration-induced illusion of movement |
Primary outcome
Mean change in the concentration of oxyhemoglobin during the task
Time frame: Day 0
The HbO2 signals are considered as indicators of the hemodynamic response.
Mean change in the concentration of deoxyhemoglobin during the task
Time frame: Day 0
The HbR signals are considered as indicators of the hemodynamic response.
1 secondary outcome
SKIP scale
Time frame: Day 0
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jul 2025.
- Background: PubMed 22490887Adamo DE, Scotland S, Martin BJ. Upper limb kinesthetic asymmetries: gender and handedness effects. Neurosci Lett. 2012 May 16;516(2):188-92. doi: 10.1016/j.neulet.2012.03.077. Epub 2012 Apr 3.
- Background: PubMed 30063911Chancel M, Landelle C, Blanchard C, Felician O, Guerraz M, Kavounoudias A. Hand movement illusions show changes in sensory reliance and preservation of multisensory integration with age for kinaesthesia. Neuropsychologia. 2018 Oct;119:45-58. doi: 10.1016/j.neuropsychologia.2018.07.027. Epub 2018 Jul 29.
- Background: PubMed 15917323Collins DF, Refshauge KM, Todd G, Gandevia SC. Cutaneous receptors contribute to kinesthesia at the index finger, elbow, and knee. J Neurophysiol. 2005 Sep;94(3):1699-706. doi: 10.1152/jn.00191.2005. Epub 2005 May 25.
- Background: PubMed 19423830Desmurget M, Reilly KT, Richard N, Szathmari A, Mottolese C, Sirigu A. Movement intention after parietal cortex stimulation in humans. Science. 2009 May 8;324(5928):811-3. doi: 10.1126/science.1169896.
- Background: PubMed 3948946Gilhodes JC, Roll JP, Tardy-Gervet MF. Perceptual and motor effects of agonist-antagonist muscle vibration in man. Exp Brain Res. 1986;61(2):395-402. doi: 10.1007/BF00239528.
- Background: PubMed 22864182Guerraz M, Provost S, Narison R, Brugnon A, Virolle S, Bresciani JP. Integration of visual and proprioceptive afferents in kinesthesia. Neuroscience. 2012 Oct 25;223:258-68. doi: 10.1016/j.neuroscience.2012.07.059. Epub 2012 Aug 3.
- Background: PubMed 17596454Hagura N, Takei T, Hirose S, Aramaki Y, Matsumura M, Sadato N, Naito E. Activity in the posterior parietal cortex mediates visual dominance over kinesthesia. J Neurosci. 2007 Jun 27;27(26):7047-53. doi: 10.1523/JNEUROSCI.0970-07.2007.
- Background: PubMed 25140108Imai R, Hayashida K, Nakano H, Morioka S. Brain Activity Associated with the Illusion of Motion Evoked by Different Vibration Stimulation Devices: An fNIRS Study. J Phys Ther Sci. 2014 Jul;26(7):1115-9. doi: 10.1589/jpts.26.1115. Epub 2014 Jul 30.
- Background: PubMed 27065525Kodama T, Nakano H, Ohsugi H, Murata S. Effects of vibratory stimulation-induced kinesthetic illusions on the neural activities of patients with stroke. J Phys Ther Sci. 2016 Jan;28(2):419-25. doi: 10.1589/jpts.28.419. Epub 2016 Feb 29.
- Background: PubMed 23073629Proske U, Gandevia SC. The proprioceptive senses: their roles in signaling body shape, body position and movement, and muscle force. Physiol Rev. 2012 Oct;92(4):1651-97. doi: 10.1152/physrev.00048.2011.
- Background: PubMed 12589891Romaiguere P, Anton JL, Roth M, Casini L, Roll JP. Motor and parietal cortical areas both underlie kinaesthesia. Brain Res Cogn Brain Res. 2003 Mar;16(1):74-82. doi: 10.1016/s0926-6410(02)00221-5.
- Background: PubMed 6705349Skinner HB, Barrack RL, Cook SD. Age-related decline in proprioception. Clin Orthop Relat Res. 1984 Apr;(184):208-11.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Canan OZSANCAK, Dr principal investigator
CHU d'Orléans
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing vibration-induced illusion of movement in people with Healthy and Stroke, Acute, run by Centre Hospitalier Régional d'Orléans at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 13 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mean change in the concentration of oxyhemoglobin during the task (time frame: Day 0). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06218563, which also lists 15 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jul 2025.