AnalgesiaNCT06230575
Locoregional Blocks for Breast Cancer Surgeries
A study testing erector spinae block, retrolaminar block and serratus anterior block in people with Analgesia, run by National Cancer Institute, Egypt at 1 site in Egypt.
Trial summary
Breast surgeries are common operative procedures that require appropriate postoperative analgesia. Read more about this study
- Who is it for?
- Ages 18 to 65 years, women only
- Conditions the study is for
- Analgesia
- What is being tested?
- erector spinae block, retrolaminar block and serratus anterior block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 188 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Feb 2024to 7 Nov 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- female cancer breast patient
- age from 18- 65
Who cannot join
- coagulation defect
- Patient refusal
- abnormal kidney and or liver function tests
Trial locations and contacts
1 site in 1 country.
About this study
Breast surgeries are common operative procedures that require appropriate postoperative analgesia.
Read the detailed description
Numerous pain relief techniques, including several new regional anesthesia techniques, are available for control of acute pain after breast surgery.
- Conditions
- Analgesia
- Being tested
- erector spinae block, retrolaminar block, serratus anterior block, pectoral nerve block
- Medical subject headings
- Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
erector spinae blockProcedure or surgery
Erector spinae plane block
retrolaminar blockProcedure or surgery
Retrolaminar block
serratus anterior blockProcedure or surgery
Serratus anterior plane block
pectoral nerve blockProcedure or surgery
Pectoral nerve block
| Study group | Role | What they receive |
|---|---|---|
| erector spinae block | Active comparator | Erector spinae plane block on the ipsilateral operative site Receives: Procedure: erector spinae block |
| retrolaminar block | Experimental | Retrolaminar plane block on the ipsilateral operative site Receives: Procedure: retrolaminar block |
| serratus anterior block | Experimental | Serratus anterior plane block on the ipsilateral operative site Receives: Procedure: serratus anterior block |
| pectoral nerve block II | Experimental | Pectoral nerve block II on the ipsilateral operative site Receives: Procedure: pectoral nerve block |
What is being measured
The primary outcome is the main question the study is designed to answer.
time to receive first postoperative analgesic
time to first dose of rescue opioid analgesic
Measured: First 24 hours postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Jan 2024
- Study start1 Feb 2024
- Primary completion15 Oct 2025
- Study completion7 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AnalgesiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 188 participants (actual)
Sponsor and investigators
- Lead sponsor
- National Cancer Institute, Egypt
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Walaa Youssef Elsabeeny, National Cancer Institute, Egypt
- Investigators
- Walaa Y Elsabeeny, MD, Principal investigator, Assistant professor of Anesthesia, Surgical critical care and Pain Management, National Cancer Institute, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06230575
- Sponsor's protocol ID
- AP2312-301-072
- Status last verified
- Nov 2025
- First submitted
- 21 Jan 2024
- Last updated
- 19 Nov 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Locoregional Blocks for Breast Cancer Surgeries
- ClinicalTrials.gov ID
- NCT06230575
- Acronym / sponsor ID
- AP2312-301-072
- Conditions
- Analgesia
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 188 participants (actual)
- Lead sponsor
- National Cancer Institute, EgyptUniversity, hospital or other
- Study start
- 1 Feb 2024 (actual)
- Primary completion
- 15 Oct 2025 (actual)
- Study completion
- 7 Nov 2025 (actual)
- First posted
- 30 Jan 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Breast surgeries are common operative procedures that require appropriate postoperative analgesia.
Detailed description
Numerous pain relief techniques, including several new regional anesthesia techniques, are available for control of acute pain after breast surgery.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| erector spinae block | Active comparator | Procedure: erector spinae blockErector spinae plane block on the ipsilateral operative site |
| retrolaminar block | Experimental | Procedure: retrolaminar blockRetrolaminar plane block on the ipsilateral operative site |
| serratus anterior block | Experimental | Procedure: serratus anterior blockSerratus anterior plane block on the ipsilateral operative site |
| pectoral nerve block II | Experimental | Procedure: pectoral nerve blockPectoral nerve block II on the ipsilateral operative site |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- female cancer breast patient
- age from 18- 65
Key exclusion criteria (3 listed)
- coagulation defect
- Patient refusal
- abnormal kidney and or liver function tests
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| erector spinae blockErector spinae plane block | Procedure or surgery | erector spinae block |
| retrolaminar blockRetrolaminar block | Procedure or surgery | retrolaminar block |
| serratus anterior blockSerratus anterior plane block | Procedure or surgery | serratus anterior block |
| pectoral nerve blockPectoral nerve block | Procedure or surgery | pectoral nerve block II |
Primary outcome
time to receive first postoperative analgesic
Time frame: First 24 hours postoperatively
time to first dose of rescue opioid analgesic
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Nov 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Walaa Y Elsabeeny, MD principal investigator
Assistant professor of Anesthesia, Surgical critical care and Pain Management, National Cancer Institute, Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing erector spinae block, retrolaminar block and serratus anterior block in people with Analgesia, run by National Cancer Institute, Egypt at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
time to receive first postoperative analgesic (time frame: First 24 hours postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Nov 2025.