StrokeNCT06239948
The Brain Symphony For Post-Stroke Rehabilitation
A study testing With Music and Without Music in people with Stroke, run by University of Malaya at 1 site in Malaysia.
Trial summary
Music listening intervention has made great strides in improving the condition of stroke survivors. Thus, this research explores the effects of music listening intervention on post-stroke survivors during rehabilitation by using P. Ramlee songs. Read more about this study
- Who is it for?
- Ages 55 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Stroke
- What is being tested?
- With Music and Without Music
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 40 participants
- Where
- 1 siteMalaysia
- Study dates
- 1 Jan 2018to 31 Dec 2020
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 55 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Healthy
- No history of seizures or epilepsy
- Able to hear well
- Able to attend experiment sessions without scheduling conflicts
- No contraindications to undergoing TMS
Who cannot join
- None
Trial locations and contacts
1 site in 1 country.
Malaysia1 site
Universiti Malaya Medical Centre
Kuala Lumpur, Kuala Lumpur, 50603
About this study
Official title: The Brain Symphony For Post-Stroke Rehabilitation - A Pilot Randomized Controlled Study With P.Ramlee Songs
Music listening intervention has made great strides in improving the condition of stroke survivors. Thus, this research explores the effects of music listening intervention on post-stroke survivors during rehabilitation by using P. Ramlee songs.
Read the detailed description
Objective: Music listening intervention has made great strides in improving the condition of stroke survivors. Thus, this research explores the effects of music listening intervention on post-stroke survivors during rehabilitation by using P. Ramlee songs.
Materials \& Methods: In the first phase, surveys were conducted to determine the selection of songs to be used in the second phase. The second phase is applying music listening intervention on a small sample of 20 subjects, aged 55 years old and above. The participants were categorized into two groups: stroke survivors and healthy individuals and randomized into control group (without music) and experimental group (with music). The second phase consists of three stages. Stage one is to pre-screen and select potential subjects before the experiment. The second stage aims to determine the effect of P. Ramlee music on stroke survivors during their rehabilitation through augmenting their brain neuroplasticity with measurement of the MEP using TMS. The final stage compares the effects of MEP between lesion and non-lesion areas.
- Conditions
- Stroke
- Being tested
- With Music, Without Music
- Keywords
- Music Listening, Stroke, Rehabilitation, Transcranial Magnetic Stimulation (TMS), Neuroplasticity, P. Ramlee Music
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
With MusicOther
each subject was placed in a TMS laboratory with music for 20 minutes
Without MusicOther
each subject was placed in a TMS laboratory without music for 20 minutes
| Study group | Role | What they receive |
|---|---|---|
| control group | Placebo comparator | without music Receives: Other: Without Music |
| experimental group | Experimental | with music Receives: Other: With Music |
What is being measured
The primary outcome is the main question the study is designed to answer.
Transcranial Magnetic Stimulation (TMS)
Wilcoxon signed-ranks test for the comparison of pre- and post- experiment
Measured: 24 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Feb 2024
- Study start1 Jan 2018
- Primary completion31 Dec 2020
- Study completion31 Dec 2020
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by University of MalayaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- The participants were categorized into two groups: stroke survivors and healthy individuals and randomized into control group (without music) and experimental group (with music).
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Malaya
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06239948
- Sponsor's protocol ID
- Brain Symphony
- Status last verified
- Jan 2024
- First submitted
- 16 Jan 2024
- Last updated
- 23 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Brain Symphony For Post-Stroke Rehabilitation - A Pilot Randomized Controlled Study With P.Ramlee Songs
- ClinicalTrials.gov ID
- NCT06239948
- Acronym / sponsor ID
- Brain Symphony
- Conditions
- Stroke
- Keywords
- Music Listening, Stroke, Rehabilitation, Transcranial Magnetic Stimulation (TMS), Neuroplasticity, P. Ramlee Music
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- University of MalayaUniversity, hospital or other
- Study start
- 1 Jan 2018 (actual)
- Primary completion
- 31 Dec 2020 (actual)
- Study completion
- 31 Dec 2020 (actual)
- First posted
- 2 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Music listening intervention has made great strides in improving the condition of stroke survivors. Thus, this research explores the effects of music listening intervention on post-stroke survivors during rehabilitation by using P. Ramlee songs.
Detailed description
Objective: Music listening intervention has made great strides in improving the condition of stroke survivors. Thus, this research explores the effects of music listening intervention on post-stroke survivors during rehabilitation by using P. Ramlee songs.
Materials \& Methods: In the first phase, surveys were conducted to determine the selection of songs to be used in the second phase. The second phase is applying music listening intervention on a small sample of 20 subjects, aged 55 years old and above. The participants were categorized into two groups: stroke survivors and healthy individuals and randomized into control group (without music) and experimental group (with music). The second phase consists of three stages. Stage one is to pre-screen and select potential subjects before the experiment. The second stage aims to determine the effect of P. Ramlee music on stroke survivors during their rehabilitation through augmenting their brain neuroplasticity with measurement of the MEP using TMS. The final stage compares the effects of MEP between lesion and non-lesion areas.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- The participants were categorized into two groups: stroke survivors and healthy individuals and randomized into control group (without music) and experimental group (with music).
| Arm | Type | Receives |
|---|---|---|
| control group | Placebo comparator | Other: Without Musicwithout music |
| experimental group | Experimental | Other: With Musicwith music |
Who may qualify
- Ages
- 55 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Healthy
- No history of seizures or epilepsy
- Able to hear well
- Able to attend experiment sessions without scheduling conflicts
- No contraindications to undergoing TMS
Key exclusion criteria (1 listed)
- None
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| With Musiceach subject was placed in a TMS laboratory with music for 20 minutes | Other | experimental group |
| Without Musiceach subject was placed in a TMS laboratory without music for 20 minutes | Other | control group |
Primary outcome
Transcranial Magnetic Stimulation (TMS)
Time frame: 24 months
Wilcoxon signed-ranks test for the comparison of pre- and post- experiment
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Dec 2025.
- Individual participant dataSharing planned: No
Related trials for Stroke
Recruiting
Connectomic Alterations Following Acute Ischemic Stroke in the MCA Territory
Ischemic Stroke
RecruitingObservational study
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
Intracerebral Hemorrhage, Stroke
Active, not recruitingPhase 4
A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment
Ischemic Stroke Hospitalized, Impairment, Cognitive
Not yet recruitingPhase 4
Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke
Ischemic Stroke
RecruitingObservational study
CoMind Early Feasibility Study
Intracranial Pressure, Intracranial Pressure Changes
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing With Music and Without Music in people with Stroke, run by University of Malaya at 1 site in Malaysia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Malaysia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Transcranial Magnetic Stimulation (TMS) (time frame: 24 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Dec 2025.