Memory, RepressedNCT06252025
Immersive VR Reminiscence System for Facilitating Memory Retrieval Among Nursing Home Older Adults
A study testing Memo-gration and Picture reminiscence therapy in people with Memory, Repressed and Emotional Regulation, run by Zhu Dian at 1 site in China.
Trial summary
A VR game "Memo-gration" was designed to assist elderly people in reminiscence therapy. The ultimate scene design was crafted in a vintage Chinese aesthetic reminiscent of the previous century. Read more about this study
- Who is it for?
- Ages 60 to 85 yearsHealthy volunteers can take part
- Conditions the study is for
- Memory, Repressed, Emotional Regulation, Old Age
- What is being tested?
- Memo-gration and Picture reminiscence therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteChina
- Study dates
- 1 Jul 2023to 1 Aug 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 to 85 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- (i) absence of significant cognitive impairment, visual impairment, hearing impairment, and communication ability.
- (ii) Obtained the pre-test and watched the film while wearing a VR headgear without experiencing any notable discomfort.
Who cannot join
- (i) Older adults with cognitive impairments that prevent normal communication
- (ii) Visually impaired
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effect of an Immersive VR Reminiscence System for Facilitating Memory Retrieval Among Nursing Home Older Adults
A VR game "Memo-gration" was designed to assist elderly people in reminiscence therapy. The ultimate scene design was crafted in a vintage Chinese aesthetic reminiscent of the previous century.
Read the detailed description
This study tailored a variety of instructional material within each virtual scenario, taking into account various memory triggers. Guidance is activated when the user is identified as making physical contact with an object or discussing a specific keyword. This encompasses textual assistance provided within the virtual environment, the display of multimedia information, and the provision of organized voice guidance. Following the system's instructions, users engaged in discussion with the caregiver, and had the freedom to terminate the conversation at their discretion and explore other topics by interacting with different items.
- Conditions
- Memory, Repressed, Emotional Regulation, Old Age
- Being tested
- Memo-gration, Picture reminiscence therapy
- Keywords
- Virtual Reality, Reminiscence Therapy
- Medical subject headings
- Emotional Regulation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Memo-grationCombination product
This study tailored a variety of instructional material within each virtual scenario, taking into account various memory triggers. Guidance is activated when the user is identified as making physical contact with an object or discussing a specific keyword. This encompasses textual assistance provided within the virtual environment, the display of multimedia information, and the provision of organized voice guidance. Following the system's instructions, users engaged in discussion with the caregiver, and had the freedom to terminate the conversation at their discretion and explore other topics by interacting with different items.
Picture reminiscence therapyOther
Picture reminiscence therapy
| Study group | Role | What they receive |
|---|---|---|
| VR reminiscence therapy system "Memo-gration" | Experimental | This study tailored a variety of instructional material within each virtual scenario, taking into account various memory triggers. Guidance is activated when the user is identified as making physical contact with an object or discussing a specific keyword. This encompasses textual assistance provided within the virtual environment, the display of multimedia information, and the provision of organized voice guidance. Following the system's instructions, users engaged in discussion with the caregiver, and had the freedom to terminate the conversation at their discretion and explore other topics by interacting with different items. Receives: Combination Product: Memo-gration |
| Picture reminiscence therapy | Active comparator | The picture reminiscence therapy group utilized a series of color images depicting screenshots of the Memo-gration, ensuring that the screenshots remained as consistent as feasible with the presented memory cues. Receives: Other: Picture reminiscence therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Profile of Mood States (POMS)
POMS is utilized to evaluate alterations in affective state and cognitive state induced by short-term psychotherapy, emotional stimuli, etc.Participants assessed their present mental state using a 5-point Likert scale, comprising 40 questions that encompassed 7 subscales measuring tension, despair, weariness, and self-esteem, etc. A comprehensive mood disturbance score (TMD) was ultimately synthesized.
Measured: baseline and 1 day (study completion)
Secondary outcomes (1)
Questionnaire on VR Experience
The UMUX-Lite and Slater-Usoh-Steed Proximity Questionnaires are combined to investigate the user experience of older persons with Memo-gration. Both assessments employ a 7-point Likert scale format.
Measured: 1 day (study completion)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Feb 2024
- Study start1 Jul 2023
- Primary completion1 Jul 2024
- Study completion1 Aug 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Memory, RepressedStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zhu Dian
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Zhu Dian, Shanghai Jiao Tong University School of Medicine
- Investigators
- Dian Zhu, Dr, Principal investigator, Shanghai Jiao Tong University School of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06252025
- Sponsor's protocol ID
- Sjtu0003
- Status last verified
- Apr 2024
- First submitted
- 24 Jan 2024
- Last updated
- 28 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of an Immersive VR Reminiscence System for Facilitating Memory Retrieval Among Nursing Home Older Adults
- ClinicalTrials.gov ID
- NCT06252025
- Acronym / sponsor ID
- Sjtu0003
- Conditions
- Memory, Repressed, Emotional Regulation, Old Age
- Keywords
- Virtual Reality, Reminiscence Therapy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Zhu DianUniversity, hospital or other
- Study start
- 1 Jul 2023 (actual)
- Primary completion
- 1 Jul 2024 (actual)
- Study completion
- 1 Aug 2024 (actual)
- First posted
- 9 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A VR game "Memo-gration" was designed to assist elderly people in reminiscence therapy. The ultimate scene design was crafted in a vintage Chinese aesthetic reminiscent of the previous century.
Detailed description
This study tailored a variety of instructional material within each virtual scenario, taking into account various memory triggers. Guidance is activated when the user is identified as making physical contact with an object or discussing a specific keyword. This encompasses textual assistance provided within the virtual environment, the display of multimedia information, and the provision of organized voice guidance. Following the system's instructions, users engaged in discussion with the caregiver, and had the freedom to terminate the conversation at their discretion and explore other topics by interacting with different items.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| VR reminiscence therapy system "Memo-gration" | Experimental | Combination Product: Memo-grationThis study tailored a variety of instructional material within each virtual scenario, taking into account various memory triggers. Guidance is activated when the user is identified as making physical contact with an object or discussing a specific keyword. This encompasses textual assistance provided within the virtual environment, the display of multimedia information, and the provision of organized voice guidance. Following the system's instructions, users engaged in discussion with the caregiver, and had the freedom to terminate the conversation at their discretion and explore other topics by interacting with different items. |
| Picture reminiscence therapy | Active comparator | Other: Picture reminiscence therapyThe picture reminiscence therapy group utilized a series of color images depicting screenshots of the Memo-gration, ensuring that the screenshots remained as consistent as feasible with the presented memory cues. |
Who may qualify
- Ages
- 60 to 85 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- (i) absence of significant cognitive impairment, visual impairment, hearing impairment, and communication ability.
- (ii) Obtained the pre-test and watched the film while wearing a VR headgear without experiencing any notable discomfort.
Key exclusion criteria (2 listed)
- (i) Older adults with cognitive impairments that prevent normal communication
- (ii) Visually impaired
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Memo-grationThis study tailored a variety of instructional material within each virtual scenario, taking into account various memory triggers. Guidance is activated when the user is identified as making physical contact with an object or discussing a specific keyword. This encompasses textual assistance provided within the virtual environment, the display of multimedia information, and the provision of organized voice guidance. Following the system's instructions, users engaged in discussion with the caregiver, and had the freedom to terminate the conversation at their discretion and explore other topics by interacting with different items. | Combination product | VR reminiscence therapy system "Memo-gration" |
| Picture reminiscence therapyPicture reminiscence therapy | Other | Picture reminiscence therapy |
Primary outcome
Profile of Mood States (POMS)
Time frame: baseline and 1 day (study completion)
POMS is utilized to evaluate alterations in affective state and cognitive state induced by short-term psychotherapy, emotional stimuli, etc.Participants assessed their present mental state using a 5-point Likert scale, comprising 40 questions that encompassed 7 subscales measuring tension, despair, weariness, and self-esteem, etc. A comprehensive mood disturbance score (TMD) was ultimately synthesized.
1 secondary outcome
Questionnaire on VR Experience
Time frame: 1 day (study completion)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Apr 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Dian Zhu, Dr principal investigator
Shanghai Jiao Tong University School of Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Memo-gration and Picture reminiscence therapy in people with Memory, Repressed and Emotional Regulation, run by Zhu Dian at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Profile of Mood States (POMS) (time frame: baseline and 1 day (study completion)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Apr 2026.