Chronic Obstructive Pulmonary Disease ModerateNCT06269029
Chest Mobility Exercises Versus Proprioceptive Neuromuscular Facilitation in Patients With COPD
A study testing Chest mobility exercises and proprioceptive neuromuscular facilitation in people with Chronic Obstructive Pulmonary Disease Moderate, run by Cairo University at 1 site in Egypt.
Trial summary
Chest mobility exercise versus proprioceptive neuromuscular facilitation in patients with chronic obstructive pulmonary disease Read more about this study
- Who is it for?
- Ages 50 to 60 years, men only
- Conditions the study is for
- Chronic Obstructive Pulmonary Disease Moderate
- What is being tested?
- Chest mobility exercises and proprioceptive neuromuscular facilitation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteEgypt
- Study dates
- 17 Feb 2024to 30 Jun 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 60 years
- Men only
- No healthy volunteers
- Adult
Who may be able to join
- All patients will have the following criteria:
- Age: 50-60 years old
- All patients will be in mild to moderate of COPD. In accordance with criteria of Global Initiative for Chronic Obstructive Lung Disease (GOLD) (GOLD I-II).
- BMI: obese class 1 (30-34.9).
- Sex: male
- They suffered from mild dyspnea, chronic cough and expectorations, with forced expiratory volume in one second (FEV1sec) from 50% to 80% of predicted value.
Who cannot join
- Patients with the following criteria will excluded from the study:
- Severe psychiatric or cognitive impairments.
- Progressive neuromuscular disorders.
- Decreased level of consciousness.
- Unstable fracture.
- pacemaker inserted for fewer than 2 days
Show all 11Show fewer
- Deep-venous thrombosis (to minimize risk for pulmonary embolism from being in a prone position.
- Mean arterial blood pressure of less than 65 mm Hg with or without vasopressors.
- Tracheal surgery or sternotomy in the last 15 days.
- Massive haemoptysis.
- Intracranial pressure of more than 30 mm Hg or cerebral perfusion pressure of less than 60 mm Hg.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Chest Mobility Exercises Versus Proprioceptive Neuromuscular Facilitation in Patients With Chronic Obstructive Pulmonary Disease
Chest mobility exercise versus proprioceptive neuromuscular facilitation in patients with chronic obstructive pulmonary disease
Read the detailed description
The purpose of this study is designed to compare the therapeutic effect of chest mobility exercises and proprioceptive neuromuscular facilitation stretching on improving chest expansion and functional capacity in patients with chronicobstructivepulmonarydisease?
- Being tested
- Chest mobility exercises, proprioceptive neuromuscular facilitation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Chest mobility exercisesOther
exercises were repeated 6 times on each side with rest of period for 30 seconds in between. The intervention will be carried out for one week with total of 7 sessions. Each Exercise will be accompanied by breathing pattern. In neutral position of exercises, subjects will be asked to exhale during flexion, turning or extension subject will be asked to do inhale.
proprioceptive neuromuscular facilitationOther
The technique used in this study Proprioceptive neuromuscular facilitation technique of hold and relax stretching for isolated clavicular head of the pectoralis major muscle. The subjects sitting on a chair with back support to keep spine in a neutral position and both their arms are extended and hands are placed behind the occipital region. His both arms will be positioned in glenohumeral horizontal extension, and glenohumeral abduction and external rotation with elbow bent to perform stretch position of pectoral muscle. Then ask him to contract the pectoral muscles .This isometric contraction is held for 6 seconds. The patient then relaxed and passive stretch in the opposite direction . and it was repeated 6 times with rest period 30 seconds. The session will be given every day for one week
| Study group | Role | What they receive |
|---|---|---|
| patients with COPD assigned for chest mobility | Experimental | This study will be carried on 30 patients with Chronic obstructivepulmonarydisease. Patients will be selected from department (3) Kaser EL-Ainy, Cairo University. Receives: Other: Chest mobility exercises |
| patients with COPD assigned for PNF | Experimental | This study will be carried on 30 patients with Chronicobstructivepulmonarydisease. Patients will be selected from department (3) Kaser EL-Ainy, Cairo University. Receives: Other: proprioceptive neuromuscular facilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pulmonary function test
Spirometry is the most common pulmonary function test. It is widely used in the assessment of lung function to provide objective information used in the diagnosis of lung diseases and monitoring lung health Test started at the time of 20 minutes after subjects inhaling 400 μg of salbutamol. The following variables were assessed: FVC, FEV1, inspiratory capacity (IC), and inspiratory reserve volume (IRV)
Measured: One week for each comparator
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Feb 2024
- Study start17 Feb 2024
- Primary completion30 Jun 2024
- Study completion30 Jun 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Chronic Obstructive Pulmonary Disease ModerateStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Isaac Zakaria Zarii Yanii, Cairo University
- Investigators
- Zahra Serry, Study director, Faculty of physical therapy- internal medicine department
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06269029
- Sponsor's protocol ID
- P.T.Rec/012/004297
- Status last verified
- Jul 2024
- First submitted
- 17 Jan 2024
- Last updated
- 22 Jul 2024
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Zakaria I, Serry ZMH, Soliman YMA, Aziz MM, Mohamed MI, Guirguis SA. Chest mobility exercises versus proprioceptive neuromuscular facilitation in patients with chronic obstructive pulmonary disease: A randomized trial. J Bodyw Mov Ther. 2025 Oct;44:400-408. doi: 10.1016/j.jbmt.2025.05.057. Epub 2025 Jun 4.
PubMed 40954608
Study at a glance
From the registry record, last updated by the sponsor on 22 Jul 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Chest Mobility Exercises Versus Proprioceptive Neuromuscular Facilitation in Patients With Chronic Obstructive Pulmonary Disease
- ClinicalTrials.gov ID
- NCT06269029
- Acronym / sponsor ID
- P.T.Rec/012/004297
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 17 Feb 2024 (actual)
- Primary completion
- 30 Jun 2024 (actual)
- Study completion
- 30 Jun 2024 (actual)
- First posted
- 21 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Chest mobility exercise versus proprioceptive neuromuscular facilitation in patients with chronic obstructive pulmonary disease
Detailed description
The purpose of this study is designed to compare the therapeutic effect of chest mobility exercises and proprioceptive neuromuscular facilitation stretching on improving chest expansion and functional capacity in patients with chronicobstructivepulmonarydisease?
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| patients with COPD assigned for chest mobility | Experimental | Other: Chest mobility exercisesThis study will be carried on 30 patients with Chronic obstructivepulmonarydisease. Patients will be selected from department (3) Kaser EL-Ainy, Cairo University. |
| patients with COPD assigned for PNF | Experimental | Other: proprioceptive neuromuscular facilitationThis study will be carried on 30 patients with Chronicobstructivepulmonarydisease. Patients will be selected from department (3) Kaser EL-Ainy, Cairo University. |
Who may qualify
- Ages
- 50 to 60 years
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Age: 50-60 years old
- All patients will be in mild to moderate of COPD. In accordance with criteria of Global Initiative for Chronic Obstructive Lung Disease (GOLD) (GOLD I-II).
- BMI: obese class 1 (30-34.9).
- Sex: male
- They suffered from mild dyspnea, chronic cough and expectorations, with forced expiratory volume in one second (FEV1sec) from 50% to 80% of predicted value.
Key exclusion criteria (11 listed)
- Severe psychiatric or cognitive impairments.
- Progressive neuromuscular disorders.
- Decreased level of consciousness.
- Unstable fracture.
- pacemaker inserted for fewer than 2 days
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Chest mobility exercisesexercises were repeated 6 times on each side with rest of period for 30 seconds in between. The intervention will be carried out for one week with total of 7 sessions. Each Exercise will be accompanied by breathing pattern. In neutral position of exercises, subjects will be asked to exhale during flexion, turning or extension subject will be asked to do inhale. | Other | patients with COPD assigned for chest mobility |
| proprioceptive neuromuscular facilitationThe technique used in this study Proprioceptive neuromuscular facilitation technique of hold and relax stretching for isolated clavicular head of the pectoralis major muscle. The subjects sitting on a chair with back support to keep spine in a neutral position and both their arms are extended and hands are placed behind the occipital region. His both arms will be positioned in glenohumeral horizontal extension, and glenohumeral abduction and external rotation with elbow bent to perform stretch position of pectoral muscle. Then ask him to contract the pectoral muscles .This isometric contraction is held for 6 seconds. The patient then relaxed and passive stretch in the opposite direction . and it was repeated 6 times with rest period 30 seconds. The session will be given every day for one week | Other | patients with COPD assigned for PNF |
Primary outcome
Pulmonary function test
Time frame: One week for each comparator
Spirometry is the most common pulmonary function test. It is widely used in the assessment of lung function to provide objective information used in the diagnosis of lung diseases and monitoring lung health Test started at the time of 20 minutes after subjects inhaling 400 μg of salbutamol. The following variables were assessed: FVC, FEV1, inspiratory capacity (IC), and inspiratory reserve volume (IRV)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jul 2024.
- Derived from this study: PubMed 40954608Zakaria I, Serry ZMH, Soliman YMA, Aziz MM, Mohamed MI, Guirguis SA. Chest mobility exercises versus proprioceptive neuromuscular facilitation in patients with chronic obstructive pulmonary disease: A randomized trial. J Bodyw Mov Ther. 2025 Oct;44:400-408. doi: 10.1016/j.jbmt.2025.05.057. Epub 2025 Jun 4.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Zahra Serry study director
Faculty of physical therapy- internal medicine department
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Chest mobility exercises and proprioceptive neuromuscular facilitation in people with Chronic Obstructive Pulmonary Disease Moderate, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Jul 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pulmonary function test (time frame: One week for each comparator). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06269029, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jul 2024.