Knee OsteoarthritisNCT06270446
Community Based Rehabilitation Model After Total Knee Replacement
A study testing Community based physiotherapy and Outpatient physiotherapy in people with Knee Osteoarthritis, run by Tan Tock Seng Hospital at 1 site in Singapore.
Trial summary
To investigate the clinical efficacy of community-based early stage knee replacement rehabilitation program as compared with usual care in acute hospital outpatient clinic Read more about this study
- Who is it for?
- Ages 55 years and older
- Conditions the study is for
- Knee Osteoarthritis
- What is being tested?
- Community based physiotherapy and Outpatient physiotherapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 59 participants
- Where
- 1 siteSingapore
- Study dates
- 1 Jan 2021to 1 Jul 2022
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 55 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- unilateral TKA; ii) age 55 years old and above; iii) able to engage in outpatient physiotherapy; iii) postoperative knee flexion ≥75° and knee extension ≤5°; iv) able to ambulate independently preoperatively.
Who cannot join
- had revision TKA or fully constrained knee arthroplasty; ii) had knee replacement for indications other than osteoarthritis; iii) had post-operative complications during hospital stay; iv) were unable to participate due to cognitive impairment or language barriers; v) had acute spinal diseases or joint, muscle or systemic diseases affecting gait; iv) had comorbid health conditions that would prevent active participation (e.g. prior hemiplegic stroke, severe cardiorespiratory illnesses.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Community Based Rehabilitation Model After Total Knee Replacement: A Pilot Study
To investigate the clinical efficacy of community-based early stage knee replacement rehabilitation program as compared with usual care in acute hospital outpatient clinic
Read the detailed description
To investigate the clinical efficacy of community-based early stage knee replacement rehabilitation program as compared with usual care in acute hospital outpatient clinic
- Conditions
- Knee Osteoarthritis
- Being tested
- Community based physiotherapy, Outpatient physiotherapy
- Medical subject headings
- Osteoarthritis, Knee
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Community based physiotherapyOther
Physiotherapy at community rehabilitation center
Outpatient physiotherapyOther
Physiotherapy at hospital
| Study group | Role | What they receive |
|---|---|---|
| Outpatient | Other | Usual care, outpatient physiotherapy Receives: Other: Outpatient physiotherapy |
| CRC | Active comparator | Community based physiotherapy Receives: Other: Community based physiotherapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
30 sec chair stand test
30 sec chair stand test score
Measured: 0, 12 weeks
Passive knee flexion range
Passive knee flexion range
Measured: 0, 4, 12 weeks
Secondary outcomes (5)
Pain intensity
Pain intensity score
Measured: 0,12 weeks
Oxford knee score
Oxford knee score
Measured: 0,12 weeks
Quadriceps muscle strength
Quadriceps muscle strength, measured from 0 to 5 on Medical Research Council scale
Measured: 0,4,12 weeks
EQ5D score
EQ5D Visual Analog Score, EQ5D Utility score
Measured: 0,12 weeks
Knee Society Score
Knee Society Score
Measured: 0,12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Feb 2024
- Study start1 Jan 2021
- Primary completion1 Jul 2022
- Study completion1 Jul 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee OsteoarthritisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 59 participants (actual)
Sponsor and investigators
- Lead sponsor
- Tan Tock Seng Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Eng Chuan Neoh, Principal investigator, Tan Tock Seng Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06270446
- Sponsor's protocol ID
- DSRB 2019/01135
- Status last verified
- Feb 2024
- First submitted
- 14 Feb 2024
- Last updated
- 24 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Community Based Rehabilitation Model After Total Knee Replacement: A Pilot Study
- ClinicalTrials.gov ID
- NCT06270446
- Acronym / sponsor ID
- DSRB 2019/01135
- Conditions
- Knee Osteoarthritis
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 59 participants (actual)
- Lead sponsor
- Tan Tock Seng HospitalUniversity, hospital or other
- Study start
- 1 Jan 2021 (actual)
- Primary completion
- 1 Jul 2022 (actual)
- Study completion
- 1 Jul 2022 (actual)
- First posted
- 21 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To investigate the clinical efficacy of community-based early stage knee replacement rehabilitation program as compared with usual care in acute hospital outpatient clinic
Detailed description
To investigate the clinical efficacy of community-based early stage knee replacement rehabilitation program as compared with usual care in acute hospital outpatient clinic
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Outpatient | Other | Other: Outpatient physiotherapyUsual care, outpatient physiotherapy |
| CRC | Active comparator | Other: Community based physiotherapyCommunity based physiotherapy |
Who may qualify
- Ages
- 55 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- unilateral TKA; ii) age 55 years old and above; iii) able to engage in outpatient physiotherapy; iii) postoperative knee flexion ≥75° and knee extension ≤5°; iv) able to ambulate independently preoperatively.
Key exclusion criteria (1 listed)
- had revision TKA or fully constrained knee arthroplasty; ii) had knee replacement for indications other than osteoarthritis; iii) had post-operative complications during hospital stay; iv) were unable to participate due to cognitive impairment or language barriers; v) had acute spinal diseases or joint, muscle or systemic diseases affecting gait; iv) had comorbid health conditions that would prevent active participation (e.g. prior hemiplegic stroke, severe cardiorespiratory illnesses.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Community based physiotherapyPhysiotherapy at community rehabilitation center | Other | CRC |
| Outpatient physiotherapyPhysiotherapy at hospital | Other | Outpatient |
Primary outcome
30 sec chair stand test
Time frame: 0, 12 weeks
30 sec chair stand test score
Passive knee flexion range
Time frame: 0, 4, 12 weeks
Passive knee flexion range
5 secondary outcomes
Pain intensity
Time frame: 0,12 weeks
Oxford knee score
Time frame: 0,12 weeks
Quadriceps muscle strength
Time frame: 0,4,12 weeks
EQ5D score
Time frame: 0,12 weeks
Knee Society Score
Time frame: 0,12 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Eng Chuan Neoh principal investigator
Tan Tock Seng Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Community based physiotherapy and Outpatient physiotherapy in people with Knee Osteoarthritis, run by Tan Tock Seng Hospital at 1 site in Singapore.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 24 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Singapore. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
30 sec chair stand test (time frame: 0, 12 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Sep 2026.