CoxarthrosisHIP3DNCT06272422
Comparison of the Restoration of Hip Biomechanical Parameters by CT Measurement Between the 3 Surgical Techniques: RSA/Minihip/THA - Hip Replacement: 3D Planning
An observational study of Coxarthrosis, run by University Hospital, Lille at 1 site in France.
Trial summary
The study will analyze hip biomechanical parameters using EOS radiographic measurements pre- and post-operatively (3 months) and post-operatively (3 months) CT scans after total hip replacement (THR), neck-preserving THR of the Minihip type or hip resurfacing (HR). Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Coxarthrosis
- What is being tested?
- hip arthroplasty
- Type of treatment
- Surgery or procedure
- How many people
- 165 participants
- Where
- 1 siteFrance
- Study dates
- 27 May 2024to 27 Aug 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients, primary care clinic at Lille University Hospital, single-center study
Who may be able to join
- Male or female
- Age ≥ 18 years
- Planned surgery: total hip arthroplasty, Minihip or RSA
- Absence of osteoarthritis or osteoarthritis ≤ stage 1 (Tönnis classification) of contralateral hip (Radiographic analysis)
- Patient having given his/her non-opposition to participate in the study
- Patient with social insurance
- Patient willing to comply with all study procedures and duration
Who cannot join
- Patient with comorbidity(ies) likely to affect biomechanical parameter measurements or surgical conditions:
- Anomalies or anatomical changes of the hip, pelvis or lumbar spine (history of fracture, protrusion, scoliosis, history of orthopedic surgery, dysplasia, torsion disorder)
- Established genetic disease affecting the musculoskeletal system
- Severe or morbid obesity
- Neuromuscular pathologies affecting the limb girdles
- Severe osteoporosis
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- Bone location of primary or metastatic cancer (spine, pelvis or femur) - Inequality of lower limb length > 2 cm.
- Minors
- Protected adults
- Pregnant or breast-feeding women
- Administrative reasons: inability to receive informed information, inability to participate in the entire study, lack of social security coverage, refusal to participate.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
chu de Lille
Lille
Julien GIRARD, MD, +33 (0)3.20.44.68.28, julien.girard@chu-lille.fr
About this study
Official title: Comparison of the Restoration of Hip Biomechanical Parameters by CT Measurement Between the 3 Surgical Techniques: RSA/Minihip/THA
The study will analyze hip biomechanical parameters using EOS radiographic measurements pre- and post-operatively (3 months) and post-operatively (3 months) CT scans after total hip replacement (THR), neck-preserving THR of the Minihip type or hip resurfacing (HR). Clinical results will be assessed at 3 months and 1 year after surgery.
To this end, two types of examination are carried out, both of which are used in current practice:
Read more
- Pre-operatively: EOS radiography
- Post-operatively: EOS radiograph and CT scan
Inclusion (m-3; m-1) :
- Patient information at pre-operative visit
- Non-opposition of patient, family member or legal guardian, if applicable
- Questionnaires and clinical examination (standard management)
- EOS during anesthetic consultation
Follow-up visit (m+3):
- Post-operative follow-up consultation EOS and CT scan (1 week prior to visit) + questionnaire and clinical examination
Follow-up visit (m+12):
- Post-operative check-up, questionnaire and clinical examination
- Conditions
- Coxarthrosis
- Being tested
- hip arthroplasty
- Keywords
- Arthroplasty hip, femoral offset, resurfacing, EOS, 3D
- Medical subject headings
- Osteoarthritis, Hip
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
hip arthroplastyProcedure or surgery
resurfacing procedures (HRP), THA and Minihip-type neck-preserving total hip arthroplasty.
| Study group | Role | What they receive |
|---|---|---|
| total hip arthroplasty (THA) | Standard THA, the head and neck of the femur are cut. Receives: Procedure: hip arthroplasty | |
| Total hip prosthesis with femoral neck preservation | A total hip replacement is performed, but the neck of the femur is preserved and the head of the femur is cut off. Receives: Procedure: hip arthroplasty | |
| Hip resurfacing | the head and neck of the femur are preserved. Receives: Procedure: hip arthroplasty |
What is being measured
The primary outcome is the main question the study is designed to answer.
Comparing the restoration of femoral hip offset between hip resurfacing procedures (HRP), THA and Minihip-type neck-preserving total hip arthroplasty.
The primary endpoint will be the difference between the native femoral offset, measured on the healthy contralateral hip, and the postoperative femoral offset of the operated hip. The offset is the distance in millimeters between the axis of the femoral shaft and the center of the femoral head.
Measured: It will be measured using CT scans at 3 months post-op for each hip.
Secondary outcomes (3)
Compare the anatomical restoration of frontal and axial parameters between the 3 types of intervention (PTH, Minihip and RSA).
Difference between the contralateral healthy hip and the operated hip at 3 months post-op of the following parameters:
- frontal parameters: CCD angle (in degrees), limb length, LLL discrepancy (vertical femoral offset in mm), femoral or prosthetic head diameter, acetabulum inclination on the healthy side and cup inclination on the operated side, head-neck ratio (ratio between the diameter of the neck and the head of the femur).
- axial parameters: femoral or prosthetic neck version, acetabulum version on healthy side and cup version on operated side, total version (neck + acetabulum or cup).
Measured: 3 months post-op
Compare clinical outcomes and patient satisfaction between the 3 procedures (PTH, Minihip and RSA).
Variations between the pre-operative and post-operative 3-month and 1-year periods in the following clinical parameters:
Oxford, Harris, PMA, Devane, UCLA, Forgotten Joint Score Hip (FJS hip), joint amplitudes, ILMI clinical estimate (in cm)
- Patient satisfaction: measured using a 4-item MCQ (dissatisfied, not very satisfied, satisfied, very satisfied) at 3 months (early recovery) and 1 year (definitive recovery).
Measured: 3 months then 1 year post-op
Correlate restoration of hip femoral offset and patient functional outcome at 3 months.
Offset restoration, defined as the difference between the native femoral offset, measured on the healthy contralateral hip, and the postoperative femoral offset of the operated hip.
- Patient functional outcome, defined by the Oxford score.
Measured: 3 months post-op
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Feb 2024
- Study start27 May 2024
- Primary completion27 Aug 2026 (estimated)
- Study completion27 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CoxarthrosisStudies of the same condition, open and under way.
- More trials run by University Hospital, LilleThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 165 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Lille
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06272422
- Sponsor's protocol ID
- 2022/0472
- Other IDs
- 2023-A00358-37
- Acronym
- HIP3D
- Status last verified
- May 2026
- First submitted
- 15 Feb 2024
- Last updated
- 19 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Restoration of Hip Biomechanical Parameters by CT Measurement Between the 3 Surgical Techniques: RSA/Minihip/THA
- ClinicalTrials.gov ID
- NCT06272422
- Acronym / sponsor ID
- HIP3D / 2022/0472
- Conditions
- Coxarthrosis
- Keywords
- Arthroplasty hip, femoral offset, resurfacing, EOS, 3D
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 165 participants (estimated)
- Lead sponsor
- University Hospital, LilleUniversity, hospital or other
- Study start
- 27 May 2024 (actual)
- Primary completion
- 27 Aug 2026 (estimated)
- Study completion
- 27 Aug 2026 (estimated)
- First posted
- 22 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study will analyze hip biomechanical parameters using EOS radiographic measurements pre- and post-operatively (3 months) and post-operatively (3 months) CT scans after total hip replacement (THR), neck-preserving THR of the Minihip type or hip resurfacing (HR). Clinical results will be assessed at 3 months and 1 year after surgery.
To this end, two types of examination are carried out, both of which are used in current practice:
- Pre-operatively: EOS radiography
- Post-operatively: EOS radiograph and CT scan
Inclusion (m-3; m-1) :
- Patient information at pre-operative visit
- Non-opposition of patient, family member or legal guardian, if applicable
- Questionnaires and clinical examination (standard management)
- EOS during anesthetic consultation
Follow-up visit (m+3):
- Post-operative follow-up consultation EOS and CT scan (1 week prior to visit) + questionnaire and clinical examination
Follow-up visit (m+12):
- Post-operative check-up, questionnaire and clinical examination
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| total hip arthroplasty (THA) | – | Procedure: hip arthroplastyStandard THA, the head and neck of the femur are cut. |
| Total hip prosthesis with femoral neck preservation | – | Procedure: hip arthroplastyA total hip replacement is performed, but the neck of the femur is preserved and the head of the femur is cut off. |
| Hip resurfacing | – | Procedure: hip arthroplastythe head and neck of the femur are preserved. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients, primary care clinic at Lille University Hospital, single-center study
Key inclusion criteria (7 listed)
- Male or female
- Age ≥ 18 years
- Planned surgery: total hip arthroplasty, Minihip or RSA
- Absence of osteoarthritis or osteoarthritis ≤ stage 1 (Tönnis classification) of contralateral hip (Radiographic analysis)
- Patient having given his/her non-opposition to participate in the study
Key exclusion criteria (11 listed)
- Patient with comorbidity(ies) likely to affect biomechanical parameter measurements or surgical conditions:
- Anomalies or anatomical changes of the hip, pelvis or lumbar spine (history of fracture, protrusion, scoliosis, history of orthopedic surgery, dysplasia, torsion disorder)
- Established genetic disease affecting the musculoskeletal system
- Severe or morbid obesity
- Neuromuscular pathologies affecting the limb girdles
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| hip arthroplastyresurfacing procedures (HRP), THA and Minihip-type neck-preserving total hip arthroplasty. | Procedure or surgery | Hip resurfacing, Total hip prosthesis with femoral neck preservation, total hip arthroplasty (THA) |
Primary outcome
Comparing the restoration of femoral hip offset between hip resurfacing procedures (HRP), THA and Minihip-type neck-preserving total hip arthroplasty.
Time frame: It will be measured using CT scans at 3 months post-op for each hip.
The primary endpoint will be the difference between the native femoral offset, measured on the healthy contralateral hip, and the postoperative femoral offset of the operated hip. The offset is the distance in millimeters between the axis of the femoral shaft and the center of the femoral head.
3 secondary outcomes
Compare the anatomical restoration of frontal and axial parameters between the 3 types of intervention (PTH, Minihip and RSA).
Time frame: 3 months post-op
Compare clinical outcomes and patient satisfaction between the 3 procedures (PTH, Minihip and RSA).
Time frame: 3 months then 1 year post-op
Correlate restoration of hip femoral offset and patient functional outcome at 3 months.
Time frame: 3 months post-op
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Coxarthrosis, run by University Hospital, Lille at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Julien GIRARD, MD (+33 (0)3.20.44.68.28, julien.girard@chu-lille.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Comparing the restoration of femoral hip offset between hip resurfacing procedures (HRP), THA and Minihip-type neck-preserving total hip arthroplasty. (time frame: It will be measured using CT scans at 3 months post-op for each hip.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.