Advanced Head and Neck Squamous Cell CarcinomaProAct-HNCNCT06272513
Influencing Factors for Physical Activity in People With Head and Neck Cancer
An observational study of Advanced Head and Neck Squamous Cell Carcinoma, run by Kantonsspital Winterthur KSW at 1 site in Switzerland.
Trial summary
The goal of this qualitative study is to explore influencing factors for physical activity (PA) participation in people affected by an advanced head and neck cancer from the perspective of people affected and their significant others. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Advanced Head and Neck Squamous Cell Carcinoma
- How many people
- 20 participants
- Where
- 1 siteSwitzerland
- Study dates
- 30 Mar 2024to 30 Jul 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: individual interview participants: 12 individuals with a diagnosis of a stage III or IV head and neck squamous cell carcinoma, after surgery \& (chemo)radiotherapy focus group interview participants: 8 significant others (partner, spouse, close familiy member or friend) of individuals with a diagnosis of a stage III or IV head and neck squamous cell carcinoma
Who may be able to join
- minimal age 18
- diagnosis of a primary head and neck squamous cell carcinoma within the last 24 months
- oral, pharyngeal, or laryngeal cancer stage III or IV
- completed surgery and/or radio(chemo)therapy in curative intent
Who cannot join
- not having the physical, mental, and cognitive ability to understand, follow and hold a conversation in (Swiss-)German
- treatment in palliative intent
- recurrence of the head and neck tumour (local or distant)
- Inclusion criteria for significant others of people with head and neck cancer:
- minimal age 18
- being a significant other (partner, spouse, close family member or friend) of an individual with a head and neck cancer with the above-mentioned criteria
Show all 9Show fewer
- having the permission of the individual affected by head and neck cancer to talk about their experiences
- Exclusion criteria for significant others of people with head and neck cancer:
- not having the physical, mental, and cognitive ability to understand, follow and take part in a group discussion in (Swiss-)German
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Exploring Influencing Factors for Physical Activity Participation in People With Advanced Head and Neck Cancer - a Qualitative Study
The goal of this qualitative study is to explore influencing factors for physical activity (PA) participation in people affected by an advanced head and neck cancer from the perspective of people affected and their significant others.
Individual interviews will be conducted with people affected by head and neck cancer and focus group interviews will be held with significant others of people being affected to answer the following research questions:
Read more
- What capabilities and opportunities for physical activity participation do people with advanced head and neck cancer experience?
- What motivates people with advanced head and neck cancer to be physically active?
- What are recommendations and suggestions for a future physical activity promotion intervention?
- How do significant others view capabilities, opportunities, and motivation for physical activity participation and promotion in people with head and neck cancer?
The interviews will be transcribed verbatim and analysed with a structuring content analysis approach.
Read the detailed description
see attached study protocol
- Keywords
- qualitative research, interviews, focus groups, physical activity, health promotion
- Medical subject headings
- Motor Activity
What is being measured
The primary outcome is the main question the study is designed to answer.
interview transcripts
individual interviews and focus group interviews will be transcribed verbatim to be analyzed
Measured: March 2024- May 2025
Secondary outcomes (1)
personal information of participants
characteristics of interview and focus group participants will be collected to be able to describe the study participants, including age, education level, cancer stage, treatment received, activity levels
Measured: March 2024- May 2025
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Feb 2024
- Study start30 Mar 2024
- Primary completion30 Jul 2025
- Study completion30 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Advanced Head and Neck Squamous Cell CarcinomaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 20 participants (actual)
Sponsor and investigators
- Lead sponsor
- Kantonsspital Winterthur KSW
- Sponsor type
- University, hospital or other
- Collaborators
- Eastern Switzerland University of Applied Sciences, University of Applied Sciences of Western Switzerland, UMC Utrecht, University of Lausanne, Zurich University of Applied Sciences
- Responsible party
- Sponsor
- Investigators
- Martina Schmocker, MSc, Principal investigator, Cantonal Hospital Winterthur, Switzerland
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06272513
- Sponsor's protocol ID
- ProAct-HNC-02
- Acronym
- ProAct-HNC
- Status last verified
- Aug 2025
- First submitted
- 15 Feb 2024
- Last updated
- 29 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Exploring Influencing Factors for Physical Activity Participation in People With Advanced Head and Neck Cancer - a Qualitative Study
- ClinicalTrials.gov ID
- NCT06272513
- Acronym / sponsor ID
- ProAct-HNC / ProAct-HNC-02
- Keywords
- qualitative research, interviews, focus groups, physical activity, health promotion
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 20 participants (actual)
- Lead sponsor
- Kantonsspital Winterthur KSWUniversity, hospital or other
- Collaborators
- Eastern Switzerland University of Applied Sciences, University of Applied Sciences of Western Switzerland, UMC Utrecht, University of Lausanne, Zurich University of Applied Sciences
- Study start
- 30 Mar 2024 (actual)
- Primary completion
- 30 Jul 2025 (actual)
- Study completion
- 30 Jul 2025 (actual)
- First posted
- 22 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this qualitative study is to explore influencing factors for physical activity (PA) participation in people affected by an advanced head and neck cancer from the perspective of people affected and their significant others.
Individual interviews will be conducted with people affected by head and neck cancer and focus group interviews will be held with significant others of people being affected to answer the following research questions:
- What capabilities and opportunities for physical activity participation do people with advanced head and neck cancer experience?
- What motivates people with advanced head and neck cancer to be physically active?
- What are recommendations and suggestions for a future physical activity promotion intervention?
- How do significant others view capabilities, opportunities, and motivation for physical activity participation and promotion in people with head and neck cancer?
The interviews will be transcribed verbatim and analysed with a structuring content analysis approach.
Detailed description
see attached study protocol
Study design
- Observational model
- Other
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- individual interview participants: 12 individuals with a diagnosis of a stage III or IV head and neck squamous cell carcinoma, after surgery \& (chemo)radiotherapy focus group interview participants: 8 significant others (partner, spouse, close familiy member or friend) of individuals with a diagnosis of a stage III or IV head and neck squamous cell carcinoma
Key inclusion criteria (4 listed)
- minimal age 18
- diagnosis of a primary head and neck squamous cell carcinoma within the last 24 months
- oral, pharyngeal, or laryngeal cancer stage III or IV
- completed surgery and/or radio(chemo)therapy in curative intent
Key exclusion criteria (9 listed)
- not having the physical, mental, and cognitive ability to understand, follow and hold a conversation in (Swiss-)German
- treatment in palliative intent
- recurrence of the head and neck tumour (local or distant)
- minimal age 18
- being a significant other (partner, spouse, close family member or friend) of an individual with a head and neck cancer with the above-mentioned criteria
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
interview transcripts
Time frame: March 2024- May 2025
individual interviews and focus group interviews will be transcribed verbatim to be analyzed
1 secondary outcome
personal information of participants
Time frame: March 2024- May 2025
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Aug 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Martina Schmocker, MSc principal investigator
Cantonal Hospital Winterthur, Switzerland
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Advanced Head and Neck Squamous Cell Carcinoma, run by Kantonsspital Winterthur KSW at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
interview transcripts (time frame: March 2024- May 2025). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Aug 2025.