Ischemic Heart DiseaseNCT06275113
BRING-UP Prevention
An observational study of Ischemic Heart Disease and Cerebrovascular Disorders, run by Heart Care Foundation at 196 sites in Italy.
Trial summary
The aim of this observational study is to assess in patients with a documented athero-thrombotic event: coronary artery disease (CAD), cerebrovascular disease (CVD), peripheral artery disease (PAD): the level of adherence to guideline recommendations with the assumption to improve the rate of patients at goal for… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Ischemic Heart Disease, Cerebrovascular Disorders, Peripheral Arterial Disease
- How many people
- 6,000 participants
- Where
- 196 sitesItaly
- Study dates
- 15 Sep 2023to 30 Jun 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients discharged (after ordinary hospitalisation or day hospital) or managed as outpatients with a documented prior athero-thrombotic event: coronary artery disease (CAD), cerebrovascular disease (CVD), peripheral artery disease (PAD).
Who may be able to join
- Both sexes at birth, age ≥18 years
- At least one of the following clinical conditions:
- Documented CAD defined as:
- Prior Acute Coronary Syndrom (ACS)
- Prior Coronary Artery Bypass Graft (CABG)
- Prior Percutaneous Coronary Intervention (PCI)
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- Documented PAD (previous peripheral bypass surgery or angioplasty, limb or foot amputation, intermittent claudication with objective evidence of peripheral artery disease, Ankle Brachial Index (ABI)<90).
- Documented CVD: Ischemic stroke, previous carotid vascular interventions.
- Signed informed consent.
Who cannot join
- Active neoplasia or very severe disease compromising short-medium term life expectancy.
- Participation in interventional studies.
- Patients already enrolled into the study from another participating center or in the previous enrolling phase.
Trial locations and contacts
196 sites in 1 country.
196 sites in 1 country
Italy196 sites, 196 recruiting
- Recruiting
Ospedale Miulli - U.O.C. Cardiologia - Utic
Acquaviva delle Fonti, BA, 70021
NICOLA VITULANO, MD
- Recruiting
Ospedale Della Murgia - Fabio Perinei - S.C. Cardiologia-Utic
Altamura, BA, 70022
PIETRO SCICCHITANO, MD
- Not yet recruiting
Ospedali Riuniti - Clinica Di Cardiologia E Aritmologia
Ancona, AN, 60122
PAOLO COMPAGNUCCI, MD
- Not yet recruiting
Ospedali Riuniti - Sod Cardiologia Ospedaliera E Utic
Ancona, AN, 60122
GIAN PIERO PERNA, MD
- Recruiting
Ospedali Riuniti Anzio-Nettuno - U.O.C. Di Cardiologia - Utic
Anzio, RM, 00042
NATALE DI BELARDINO, MD
- Recruiting
Osp. San Pancrazio-Santo Stefano - Riabilitazione Cardiologica
Arco, TN, 38062
GIOVANNI CIOFFI, MD
- Recruiting
Ospedale San Donato - U.O.C Cardiologia
Arezzo, AR, 52100
MATTEO ROCCO RECCIA, MD
- Recruiting
Ospedale Dei Castelli - U.O.C. Di Cardiologia E Utic
Ariccia, RM, 00072
FRANCESCO MONTI, MD
- Recruiting
Ospedale Civile - U.O.C. Di Cardiologia
Arzignano, VI, 36071
CLAUDIO BILATO, MD
- Recruiting
Aorn San Giuseppe Moscati - U.O. Cardiologia/Utic 'D. Rotiroti'
Avellino, AV, 83100
EMILIO DI LORENZO, MD
- Recruiting
Ospedale San Paolo - Cardiologia-Utic
Bari, BA, 70123
PASQUALE CALDAROLA, MD
- Recruiting
Ics Maugeri Spa Societa' Benefit Irccs Bari - Cardiologia Riabilitativa
Bari, BA, 70124
ANDREA PASSANTINO, MD
- Recruiting
Mater Dei Hospital - Riabilitazione Cardiologica
Bari, BA, 70124
ROCCO LAGIOIA, MD
- Not yet recruiting
Ospedale Monsignor Angelo R. Di Miccoli - Uoc Cardiologia/Utic
Barletta, BT, 76121
FRANCESCO BARTOLOMUCCI, MD
- Recruiting
Ospedale Di Bentivoglio - U.O. Cardiologia Pianura
Bentivoglio, BO, 40010
GIANFRANCO TORTORICI, MD
- Recruiting
Ospedale Maggiore - U.O.C. Di Cardiologia
Bologna, BO, 40133
GIANMARCO IANNOPOLLO, MD
- Recruiting
Ospedale Bellaria - U.O. Di Cardiologia
Bologna, BO, 40139
STEFANO URBINATI, MD
- Recruiting
Ospedale Centrale Bolzano - Cardiologia E Prove Funzionali
Bolzano, BZ, 39100
PRISCILLA MILEWSKI, MD
- Recruiting
Ospedale Ss. Trinita' - S.C. Di Cardiologia
Borgomanero, 28021
PIERFRANCO S DELLAVESA, MD
- Recruiting
Casa Di Cura San Camillo - U.O. Cardiologia
Brescia, BS, 25123
MARCO CAPRETTI, MD
- Recruiting
Ospedale Perrino - U.O.C. Di Cardiologia
Brindisi, BR, 72100
GIAN PAOLO GIORDA, MD
- Not yet recruiting
Arnas G. Brotzu - Cardiologia Con Utic
Cagliari, CA, 09134
MARCO CORDA, MD
- Recruiting
Arnas G. Brotzu - S.S.D. Cardioriabilitazione
Cagliari, CA, 09134
ANDREA BIANCO, MD
- Recruiting
Nuovo Ospedale Versilia - Sc Cardiologia
Camaiore, LU, 55041
GIANCARLO CASOLO, MD
- Not yet recruiting
Ospedale Barone Lombardo - Cardiologia E Utic
Canicattì, AG, 92024
LUCIANO SUTERA SARDO, MD
- Recruiting
Ospedale Santo Spirito - Sc Cardiologia
Casale Monferrato, AL, 15033
FEDERICO NARDI, MD
- Recruiting
Ospedale Oglio Po - U.O. Di Cardiologia-Utic
Casalmaggiore, CR, 26041
CARLO PISCICELLI, MD
- Recruiting
Presidio Ospedaliero F. Ferrari - Ssd Cardiologia - Utic
Casarano, LE, 73042
DONATO MELISSANO, MD
- Recruiting
Azienda Ospedaliera S. Anna E S. Sebastiano - U.O. Cardiologia D'Emergenza Con Utic
Caserta, CE, 81100
PAOLO CALABRO', MD
- Recruiting
Villa Delle Magnolie - Riabilitazione Cardiologica
Castel Morrone, CE, 81020
FRANCESO PERONE, MD
- Recruiting
Ospedale Unico Della Val Tidone - Cardiologia E Riabilitazione
Castel San Giovanni, PC, 29015
MARIATERESA DI DIO, MD
- Recruiting
Ospedale Multimedica Castellanza - Cardiologia
Castellanza, VA, 21053
ANNA PICOZZI, MD
- Not yet recruiting
Policlinico Di Catania Presidio San Marco - Cardiologia Utic
Catania, CT, 95100
ALESSIO G LA MANNA, MD
- Recruiting
P.O. Garibaldi-Nesima - Arnas Garibaldi - U.O.C. Di Cardiologia Con Utic
Catania, CT, 95122
MICHELE M GULIZIA, MD
- Recruiting
P.O. "Materdomini" - A.O.U. "Renato Dulbecco" - Ssd Cardiologia Riabilitativa
Catanzaro, CZ, 88100
DOMENICO ZUCCO, MD
- Recruiting
Fondazione G. Giglio - U.O. Di Cardiologia
Cefalù, PA, 90015
DONATELLA ARMATA, MD
- Not yet recruiting
Ospedale Di Cernusco Sul Naviglio - U. O. Di Cardiologia E Ucc
Cernusco sul Naviglio, MI, 20063
SERGIO SALA, MD
- Not yet recruiting
Ospedale Policlinico Ss. Annunziata - Uoc Cardiologia-Utic
Chieti, CH, 66013
MARCO ZIMARINO, MD
- Recruiting
Por Cirie' Lanzo Presidio Cirie' - S.C. Cardiologia
Cirié, TO, 10073
Michele Capriolo, MD
- Recruiting
Presidio Ospedaliero Citta' Di Castello - U.O. Cardiologia/Utic
Città di Castello, PG, 06012
ANDREA CHIOCCHINI, MD
- Recruiting
Ospedale Di Cittadella - U.O. Cardiologia
Cittadella, PD, 35013
GAETANO POVOLO, MD
- Recruiting
Ospedale Civile San Paolo - U.O.C. Cardiologia - Utic
Civitavecchia, RM, 00053
SIMONE CALCAGNO, MD
- Not yet recruiting
Ospedale L. Parodi Delfino - U.O.C. Di Cardiologia - Utic
Colleferro, RM, 00034
ROBERTA IPPEDICO, MD
- Not yet recruiting
Ospedale San Giuseppe Da Copertino - U.O. Di Cardiologia
Copertino, LE, 73043
ALESSANDRO CALCAGNILE, MD
- Recruiting
Ospedale Umberto I - U.O.C. Cardiologia
Corato, BA, 70033
ILARIA L NALIN, MD
- Recruiting
Ospedale Valdichiana Santa Margherita - Uosd Cardiologia S.O. Cortona
Cortona, AR, 52044
SIMONA D'ORAZIO, MD
- Recruiting
Ospedale Annunziata - Uoc Cardiologia Interventistica
Cosenza, CS, 87100
FRANCESCO GRECO, MD
- Recruiting
Azienda Ospedaliera Santa Croce E Carle - Sc Cardiologia
Cuneo, CN, 12100
FRANCESCA GIORDANA, MD
- Recruiting
Ospedale Di Desenzano Del Garda - Divisione Di Cardiologia - U.C.C.
Desenzano del Garda, BS, 25015
GIOSUE' MASCIOLI, MD
- Recruiting
Ospedale Pio Xi - U.O.C. Di Cardiologia
Desio, MB, 20832
FELICE ACHILLI, MD
- Recruiting
Casa Di Cura Pineta Del Carso - U.O. Riabilitazione Cardiologica
Duino-Aurisina, TS, 34011
LARA GOMBAC, MD
- Recruiting
Ospedale Maria Ss. Addolorata - U.O. Di Cardiologia Utic
Eboli, SA, 84025
EDUARDO CAPUANO, MD
- Recruiting
Presidio Ospedaliero "Santa Maria Del Prato" - U.O.C. Di Cardiologia-Utic
Feltre, BL, 32032
CHRISTIAN PIERGENTILI, MD
- Recruiting
Arcispedale Sant'Anna - U.O. Cardiologia
Ferrara, FE, 44124
GABRIELE GUARDIGLI, MD
- Recruiting
Ospedale Civile - U.O.C. Cardiologia - Utic
Fidenza, PR, 43036
GIOVANNI TORTORELLA, MD
- Recruiting
Aou Careggi - Riabilitazione Cardiologica
Florence, FI, 50134
COSTANZA BURGISSER, MD
- Recruiting
Policlinico Riuniti - S.C. Di Cardiologia Universitaria-Utic
Foggia, FG, 71100
NATALE D BRUNETTI, MD
- Recruiting
San Francesco Hospital - U.O.C. Cardiologia
Foggia, FG, 71122
ALDO RUSSO, MD
- Recruiting
Ospedale G.B. Morgagni - L. Pierantoni - U.O. Cardiologia
Forlì, FC, 47121
DANIELA SPARTA', MD
- Recruiting
Ospedale San Giovanni Di Dio - Uo Cardiologia - Utic
Frattamaggiore, Napoli, 80027
FRANCESCO PIEMONTE, MD
- Recruiting
Istituti Clinici Scientifici Maugeri Irccs Sede Di Veruno - Uo Cardiologia Riabilitativa
Gattico, 28013
MASSIMO PISTONO, MD
- Recruiting
Ospedale Civile 'La Memoria' - U.O. Di Cardiologia
Gavardo, BS, 25085
MARCO TRIGGIANI, MD
- Recruiting
Santa Barbara Hospital - Cardiologia
Gela, CL, 93012
GIUSEPPE LA ROSA, MD
- Recruiting
E.O. Ospedali Galliera - S. C. Cardiologia E U.T.I.C.
Genova, GE, 16128
MARIA MOLFESE, MD
- Recruiting
Presidio Ospedaliero San Giugliano - U.O. Cardiologia - Utic
Giugliano in Campania, 80014
GIOVANNI NAPOLITANO, MD
- Recruiting
Ospedale San Giovanni Di Dio - Sc Cardiologia (Gorizia-Monfalcone)
Gorizia, GO, 34170
GERARDINA LARDIERI, MD
- Recruiting
Ospedale Civile Di Guastalla - Sos Cardiologia E Riabilitazione Card Area Nord
Guastalla, RE, 42016
ALESSANDRO NAVAZIO, MD
- Recruiting
Ospedale Gubbio-Gualdo Tadino - U.O. Di Utic E Cardiologia
Gubbio, PG, 06024
DEBORAH COSMI, MD
- Recruiting
Casa Di Cura Villa Serena - U.O. Cardiologia Riabilitativa
Iesi, AN, 60035
NICOLA RUSSO, MD
- Recruiting
Istituto 'Marco Pasquali' Icot - Riabilitazione Cardiologica
Latina, LT, 04100
ANTONIO GROSSI, MD
- Recruiting
Ospedale Vito Fazzi - Uoc Cardiologia-Utic Ed Emodinamica
Lecce, LE, 73100
STEFANIA MARAZIA, MD
- Recruiting
Ospedale Alessandro Manzoni - S.C. Di Cardiologia
Lecco, LC, 23900
ROBERTO SPOLADORE, MD
- Recruiting
P.O. Lentini - Uosd Di Cardiologia Con Utic
Lentini, SR, 96016
VINCENZO CRISCI, MD
- Recruiting
Ospedale San Giacomo D'Altopasso - Uoc Cardiologia
Licata, AG, 92027
SALVATORE MONTALTO, MD
- Recruiting
Ospedali Riuniti - U.O.C. Cardiologia E Utic
Livorno, LI, 57124
FRANCESCO BELLINI, MD
- Recruiting
Ospedale Civile - Uo Servizio Cardiologia
Lugo, RA, 48022
GIULIA RICCI LUCCHI, MD
- Recruiting
Istituti Clinici Scientifici Maugeri Irccs Sede Di Lumezzane - U.O. Di Cardiologia Riabilitativa
Lumezzane, BS, 25065
FRANCESCA RIVADOSSI, MD
- Recruiting
Casa Di Cura San Michele - Uo Cardiologia
Maddaloni, CE, 81024
MARCO PEPE, MD
- Not yet recruiting
Ospedale Madonna Delle Grazie - Ssd Utic
Matera, 75100
MICHELE A CLEMENTE, MD
- Recruiting
Iomi Istituto Ortopedico F. Scalabrino - Uo Cardiologia
Messina, ME, 98015
ROBERTO CARUSO, MD
- Recruiting
Irccs Centro Neurolesi Bonino Pulejo - P.O Piemonte - Cardiologia E Utic
Messina, ME, 98124
ANTONIO DUCA, MD
- Recruiting
Azienda Ospedaliera Papardo - U.O. Cardiologia Con Utic - Emodinamica
Messina, ME, 98158
VITO PIPITONE, MD
- Recruiting
Ospedale Dell'Angelo - U.O.C. Cardiologia
Mestre, VE, 30171
SAKIS THEMISTOCLAKIS, MD
- Recruiting
Policlinico San Marco - Riabilitazione Cardiologica
Mestre, VE, 30173
FRANCO DEL PICCOLO, MD
- Recruiting
Fondazione Irccs Ca' Granda Ospedale Maggiore Policlinico - Uoc Malattie Cardiovascolari
Milan, MI, 20122
STEFANO CARUGO, MD
- Recruiting
Centro Cardiologico Monzino Irccs - Terapia Intensiva Cardiologica (Utic)
Milan, MI, 20138
FILIPPO TOMBARA, MD
- Recruiting
Istituti Clinici Scientifici Maugeri Irccs Sede Di Milano - Riabilitazione Cardiologica
Milan, MI, 20138
MAURIZIO BUSSOTTI, MD
- Recruiting
Istituti Clinici Scientifici Maugeri Irccs Sede Di Milano - Uo Cure Subacute
Milan, MI, 20138
MARCO FROLDI, MD
- Recruiting
Irccs Santa Maria Nascente Fond. Don Gnocchi - Cardiologia Riabilitativa
Milan, MI, 20148
ANDREA A MORASCHI, MD
- Recruiting
ASST SANTI PAOLO E CARLO - PO San Carlo - CARDIOLOGIA-UCC
Milan, MI, 20153
MARTA RESCALDANI, MD
- Recruiting
Irccs Ospedale Galeazzi - Sant'Ambrogio - Cardiologia Universitaria Ed Imaging Cardiaco
Milan, MI, 20157
EDOARDO CONTE, MD
- Recruiting
Asst Ospedale Metropolitano Niguarda - Diagnosi E Cure Terr. Malattie Cardiache
Milan, MI, 20159
GIULIANA G MOMBELLI, MD
- Recruiting
Asst Ospedale Metropolitano Niguarda - Cardiologia 1 - Emodinamica
Milan, MI, 20162
LAURA GARATTI, MD
- Recruiting
Asst Ospedale Metropolitano Niguarda - Cardiologia 4 - Diagnostica E Riabilitativa
Milan, MI, 20162
ALESSANDRO MALOBERTI, MD
- Recruiting
Ospedale Santa Maria Bianca - U.O. Di Cardiologia
Mirandola, MO, 41037
GIULIA NANNI, MD
- Recruiting
Ospedale Civile Di Baggiovara - U.O. Di Cardiologia
Modena, MO, 41126
STEFANIA SANSONI, MD
- Recruiting
Ospedale Regina Montis Regalis - U.O. Cardiologia-Utic
Mondovì, CN, 12084
MAURO FEOLA, MD
- Not yet recruiting
Ospedale Civile San Polo - Sc Cardiologia (Gorizia-Monfalcone)
Monfalcone, GO, 34074
GERARDINA LARDIERI, MD
- Recruiting
Ospedale San Giacomo - Uoc Cardiologia
Monopoli, BA, 70043
ONOFRIO ROSSI, MD
- Not yet recruiting
A.O.U. Cagliari Policlinico Monserrato - Sc Cardiologia Utic Emodinamica
Monserrato, CA, 09124
ROBERTA MONTISCI, MD
- Recruiting
Ospedale E. Franchini - S.O.S. Cardiologia
Montecchio Emilia, RE, 42027
ELISABETTA CATELLANI, MD
- Recruiting
Fondazione Irccs San Gerardo Dei Tintori - Ospedale San Gerardo - U.O.C. Cardiologia
Monza, MB, 20900
LAURA F VALAGUSSA, MD
- Recruiting
Ospedale Buon Consiglio Fatebenefratelli - U.O.Complessa Di Cardiologia E Utic
Naples, 80123
GAETANO M RUOCCO, MD
- Recruiting
Aorn Cardarelli - U.O. Cardiologia Con Utic
Naples, 80131
CIRO MAURO, MD
- Recruiting
Aorn Ospedale Dei Colli - P.O. Monaldi - Uosd Malattie Cardiologiche Congenite Adulti-Guch
Naples, 80131
BERARDO SARUBBI, MD
- Not yet recruiting
Ospedale Dei Pellegrini - Uoc Cardiologia-Utic
Naples, 80134
GIUSEPPE BRUZZESE, MD
- Recruiting
Ospedale S. Giovanni Bosco - Sc Cardiologia - Utic
Naples, 80134
PAOLO TAMMARO, MD
- Recruiting
Ospedale Del Mare - U.O. Cardiologia Con Utic-Emodinamica
Naples, 80147
BERNARDINO TUCCILLO, MD
- Recruiting
Irccs Ospedale Sacro Cuore Don Calabria - U.O. Di Cardiologia
Negrar, VR, 37024
GIULIO MOLON, MD
- Not yet recruiting
Icr Villa Delle Querce - Riabilitazione Cardiorespiratoria
Nemi, RM, 00040
MICHELE AZZARITO, MD
- Recruiting
Ospedale P.F. Calvi - Uos Di Cardiologia Riabilitativa
Noale, VE, 30033
VALENTINA PESCATORE, MD
- Recruiting
Presidio Ospedaliero Umberto I - Uoc Cardiologia - Utic
Nocera Inferiore, SA, 84014
MARIO PACILEO, MD
- Recruiting
Aou Maggiore Della Carita' - Scdo Cardiologia Ii
Novara, 28100
LIDIA ROSSI, MD
- Recruiting
Clinica San Gaudenzio - Uoa Cardiologia
Novara, 28100
NADIA PODIMANI, MD
- Recruiting
Ospedale San Giacomo - Sc Cardiologia
Novi Ligure, AL, 15067
MARIA E ROVERE, MD
- Recruiting
Aou San Luigi Gonzaga - S.C.D.O. Cardiologia
Orbassano, TO, 10043
Carloalberto Biolù, MD
- Recruiting
Ospedale Buccheri La Ferla Fatebenefratelli - Ssd Riabilitazione Cardiovascolare
Palermo, PA, 90123
FILIPPO M SARULLO, MD
- Recruiting
Aou Policlinico P. Giaccone - U.O.C. Cardiologia
Palermo, PA, 90127
GIUSEPPINA NOVO, MD
- Recruiting
Arnas P.O. Civico E Benfratelli - Uoc Utic
Palermo, PA, 90127
IGNAZIO M SMECCA, MD
- Recruiting
Maria Eleonora Hospital - Cardiologia
Palermo, PA, 90135
VINCENZO PERNICE, MD
- Recruiting
Aor Villa Sofia-Cervello P.O. Cervello - U.O. Cardiologia - Cervello
Palermo, PA, 90146
VINCENZO POLIZZI, MD
- Recruiting
Aor Villa Sofia-Cervello Po Villa Sofia - Uoc Cardiologia E Utic E Emodinamica -Villa Sofia
Palermo, PA, 90146
CARLO CICERONE, MD
- Recruiting
Ospedale Spoke Paola- Cetraro Po Paola - Utic Cardiologia
Paola, CS, 87027
MARIA T MANES, MD
- Recruiting
Istituto Don Gnocchi - U.O. Prevenzione E Riabilitazione Cardiovascolare
Parma, PR, 43100
UMBERTO CAMAIORA, MD
- Recruiting
Istituti Clinici Scientifici Maugeri Irccs Sede Di Pavia - U.O. Di Riabilitazione Cardiologica
Pavia, PV, 27100
GIOVANNI FORNI, MD
- Recruiting
Azienda Ospedaliera Di Perugia - S.C. Cardiologia
Perugia, PG, 06129
FRANCESCO NOTARISTEFANO, MD
- Recruiting
Presidio Ospedaliero San Salvatore - Cardiologia E Utic
Pesaro, PU, 61121
SIMONE MAFFEI, MD
- Recruiting
Ospedale Civile Dello Spirito Santo - Cardiologia Con Utic
Pescara, PE, 65124
DOMENICO DI CLEMENTE, MD
- Recruiting
Ospedale Ss. Cosma E Damiano - Sos Cardiologia
Pescia, Pistoia, 51017
GAIA C MAGNAGHI, MD
- Recruiting
Ospedale Ss. Cosma E Damiano - Sos Riabilitazione Cardiologica
Pescia, Pistoia, 51017
DUCCIO ROSSINI, MD
- Recruiting
Ospedale Civile 'Guglielmo Da Saliceto' - Uoc Cardiologia E Utic
Piacenza, PC, 29100
DANIELA ASCHIERI, MD
- Recruiting
Po Ponente - Ospedale Santa Corona - Sc Cardiologia Ponente
Pietra Ligure, SV, 17027
CHIARA BERNELLI, MD
- Recruiting
Casa Di Cura Villa Serena - Riabilitazione Cardiorespiratoria
Piossasco, TO, 10045
ALEX MICANTI, MD
- Recruiting
Ftgm - Stabilimento Di Pisa - Cardiologia E Medicina Cardiovascolare
Pisa, PI, 56124
MICHELE EMDIN, MD
- Not yet recruiting
Ospedale Giovanni Paolo Ii - Uosd Utic
Policoro, Matera, 75025
ANDREA ANDRIANI, MD
- Recruiting
Presidio Ospedaliero Luigi Curto - Uo Cardiologia-Utic
Polla, SA, 84035
SILVIO SAPONARA, MD
- Recruiting
Ospedale Degli Infermi - Sc Di Cardiologia
Ponderano, BI, 13875
ANDREA ROGNONI, MD
- Not yet recruiting
Ospedale Santa Maria Delle Grazie - U.O. Cardiologia - Utic Con Emodinamica
Pozzuoli, 80078
GIANLUIGI TAGLIAMONTE, MD
- Recruiting
Ospedale Generale Provinciale - U.O. Cardiologia
Province of Macerata, MC, 62100
MICAELA CAPPONI, MD
- Recruiting
Ospedale Civile Santa Maria Delle Croci - Uoc Cardiologia
Ravenna, RA, 48121
ANDREA RUBBOLI, MD
- Recruiting
Po Santa Maria Nuova - Ausl Re Irccs - Soc Cardiologia Ospedaliera
Reggio Emilia, RE, 42100
ALESSANDRO NAVAZIO, MD
- Recruiting
Presidio Ospedaliero Di Passirana - Cardiologia Riabilitativa
Rho, MI, 20017
ANNA FRISINGHELLI, MD
- Recruiting
P.O. San Camillo de Lellis - U.O.C. Cardiologia
Rieti, RI, 02100
AMIR KOL, MD
- Not yet recruiting
Ospedale Infermi - U.O. Cardiologia
Rimini, RN, 47900
ANDREA GARDI, MD
- Recruiting
Ospedale Degli Infermi - Sc Cardiologia
Rivoli, TO, 10098
EMANUELE TIZZANI, MD
- Recruiting
P.O. San Filippo Neri - Asl Roma 1 - Cardiologia Clinica E Riabilitativa
Roma, RM, 00135
FURIO COLIVICCHI, MD
- Recruiting
Inmi Lazzaro Spallanzani Irccs - Servizio Di Cardiologia Del Dipartimento Clinico
Roma, RM, 00149
MARIA C GATTO, MD
- Recruiting
Ospedale San Camillo - Uoc Cardiologia
Roma, RM, 00152
LEONARDO DE LUCA, MD
- Recruiting
Ospedale Sandro Pertini - Uoc Cardiologia
Roma, RM, 00157
ANTONINO GRANATELLI, MD
- Recruiting
Ospedale Sandro Pertini - Uosd Cardiologia D'Urgenza
Roma, RM, 00157
STEFANIA CHERUBINI, MD
- Not yet recruiting
Fondazione Policlinico Universitario A. Gemelli Irccs - Uosd Cardiologia D'Urgenza
Roma, RM, 00168
GIOVANNA LIUZZO, MD
- Recruiting
Policlinico Casilino - U.O.C. Cardiologia
Roma, RM, 00169
LEONARDO CALO', MD
- Not yet recruiting
Osp. Fatebenefratelli Isola Tiberina - Uoc Cardiologia Diagnostica Interventistica-Utic
Roma, RM, 00188
MATTEO RUZZOLINI, MD
- Recruiting
Ospedale Sant'Andrea Di Roma - U.O.C. Cardiologia
Roma, RM, 00189
EMANUELE BARBATO, MD
- Recruiting
Ospedale Santo Spirito - Uoc Cardiologia
Roma, RM, 00193
MARINA DELFINI, MD
- Recruiting
Presidio Ospedaliero Per La Salute Di Sacile - Cardiologia Preventiva E Riabilitativa
Sacile, PN, 33077
ELISA LEIBALLI, MD
- Recruiting
Aou S. Giovanni Di Dio-Ruggi D'Aragona - Cardiologia Intensiva Ospedaliera
Salerno, SA, 84131
MICHELE R DI MURO, MD
- Recruiting
Aou S. Giovanni Di Dio-Ruggi D'Aragona - Ssd Utic
Salerno, SA, 84131
AMELIA RAVERA, MD
- Recruiting
Aou S. Giovanni Di Dio-Ruggi D'Aragona - Uoc Clinica Cardiologica
Salerno, SA, 84131
MICHELE CICCARELLI, MD
- Recruiting
Ospedale Madonna Del Soccorso - Uoc Cardiologia Indirizzo Riabilitativo
San Benedetto del Tronto, AP, 63074
MICHELA MOLISANA, MD
- Recruiting
Ospedale G. Fracastoro - U.O.C. Di Cardiologia
San Bonifacio, VR, 37047
MAURIZIO ANSELMI, MD
- Not yet recruiting
Ospedale Civile - U.O.C. Di Cardiologia
San Donà di Piave, VE, 30027
LEONARDO DI ASCENZO, MD
- Recruiting
Irccs Policlinico San Donato - Cardiologia Riabilitativa
San Donato Milanese, MI, 20097
MASSIMO PIEPOLI, MD
- Recruiting
Ospedale Casa Sollievo Della Sofferenza - Cardiologia - Utic - Riabil Cardiologica
San Giovanni Rotondo, FG, 71013
GIUSEPPE DI STOLFO, MD
- Recruiting
Ospedale Di S. Vito Al Tagliamento - Ssd Cardiologia San Vito - Spilimbergo
San Vito al Tagliamento, PN, 33078
DANIELA PAVAN, MD
- Recruiting
Presidio Ospedaliero - U.O. Cardiologia
Sanremo, IM, 18038
FABIO FERRARI, MD
- Recruiting
Ospedale San Giuseppe E Melorio - U.O.C. Cardiologia Utic
Santa Maria Capua Vetere, CE, 81055
PIETRO IODICE, MD
- Recruiting
Ospedale Alto Vicentino - U.O.C. Cardiologia - Ucic
Santorso, VI, 36014
GIOVANNI MORANI, MD
- Recruiting
Ospedale Villa Malta - Cardiologia E Utic
Sarno, SA, 84087
MARIA C RUSSO, MD
- Recruiting
Presidio Ospedaliero Di Saronno - U.O.C. Di Cardiologia
Saronno, VA, 21047
DANIELE NASSIACOS, MD
- Recruiting
Ospedale San Bartolomeo - Sc Riabilitazione Cardiologica
Sarzana, SP, 19038
DANIELE BERTOLI, MD
- Recruiting
Ospedale Ss. Annunziata - Cardiologia Clinica Ed Interventistica
Sassari, SS, 07100
GAVINO CASU, MD
- Recruiting
Ospedale Di Sassuolo - Cardiologia
Sassuolo, MO, 41049
WALTER SACCO, MD
- Recruiting
Ospedale Maggiore Ss. Annunziata - Sc Cardiologia
Savigliano, CN, 12038
MICHELE DE BENEDICTIS, MD
- Recruiting
Ospedale Ignazio Veris Delli Ponti - Uoc Cardiologia-Utic "E. Vilei"
Scorrano, LE, 73020
COSIMO A GRECO, MD
- Recruiting
Ospedale Di Seregno - Riabilitazione Specialistica Cardiologica
Seregno, MB, 20831
ELISABETTA SCANZIANI, MD
- Recruiting
Irccs Policlinico Multimedica - Uo Di Cardiologia
Sesto San Giovanni, MI, 20099
LUCA P ALBERTI, MD
- Recruiting
Ospedale Citta' Di Sesto San Giovanni - Sc Cardiologia-Ucc Asst Nord Milano (Bassini-Ssg)
Sesto San Giovanni, MI, 20099
CAMILLA FACCHINI, MD
- Recruiting
Aou Senese Ospedale S. Maria Alle Scotte - Cardiologia
Siena, SI, 53100
SERAFINA VALENTE, MD
- Recruiting
Casa Di Cura Villa Verde - Cardiologia
Taranto, TA, 74100
ANNA N JOHN, MD
- Recruiting
Ospedale San Giovanni Evangelista - U.O.C. Di Cardiologia - Utic
Tivoli, RM, 00019
ALFREDO POSTERARO, MD
- Recruiting
Ospedale San Giovanni Bosco - Sc Cardiologia
Torino, TO, 10154
MAURIZIO BERTAINA, MD
- Recruiting
Ospedale Mauriziano Umberto I - Sc Cardiologia
Torino, 10128
Giuseppe Musumeci, MD
- Not yet recruiting
Ospedale Di Circolo Galmarini - Cardiologia
Tradate, VA, 21049
MASSIMO BIGNOTTI, MD
- Recruiting
Ospedale Santa Chiara - Divisione Di Cardiologia
Trento, TN, 38122
FILIPPO ZILIO, MD
- Recruiting
Asugi Trieste - Sc Patologie Cardiovascolari
Trieste, TS, 34125
LUISA MATTEI, MD
- Recruiting
Pou "Santa Maria Della Misericordia" - S.O.C. Cardiologia
Udine, UD, 33100
MARIZA DE BIASIO, MD
- Recruiting
Ospedale San Luca - U.O. Utic - Cardiologia
Vallo della Lucania, SA, 84078
ANTONIO ALOIA, MD
- Recruiting
Ospedale Sant'Andrea - Sc Cardiologia
Vercelli, VC, 13100
MARIA BERTOLAZZI, MD
- Recruiting
Aoui Di Verona - U.O. Cardiologia
Verona, VR, 37126
MARIA G GASPARI, MD
- Recruiting
Ospedale Civile San Bortolo - U.O.C. Cardiologia
Vicenza, VI, 36100
VALENTINA SIVIERO, MD
- Recruiting
Nuovo Ospedale Di Vimercate - S.C. Cardiologia E Utic
Vimercate, MB, 20871
DANIELA GRASSELLI, MD
- Recruiting
Ospedale Belcolle - Uoc Cardiologia Ed Emodinamica
Viterbo, VT, 01100
LUIGI SOMMARIVA, MD
- Recruiting
Ospedale Riccardo Guzzardi - U.O.C. Di Cardiologia-Utic
Vittoria, RG, 97019
GIUSEPPE DI STABILE, MD
- Recruiting
Ospedale Civile - U.O. Di Cardiologia
Voghera, PV, 27058
TIZIANA SPEZZANO, MD
- Recruiting
Auxilium Vitae Volterra - Riabilitazione Cardiologica
Volterra, PI, 56048
NICOLA SCELZA, MD
About this study
The aim of this observational study is to assess in patients with a documented athero-thrombotic event: coronary artery disease (CAD), cerebrovascular disease (CVD), peripheral artery disease (PAD):
- the level of adherence to guideline recommendations with the assumption to improve the rate of patients at goal for cholesterol levels.
- the level of adherence to guideline recommendations and the rate of patients at goal for the other relevant and modifiable risk factors for cardiovascular event recurrence.
Read the detailed description
Observational, prospective, multicenter study conducted in a large, representative sample of Italian cardiology centers.
Phases:
- First educational intervention to discuss the recommendations of guidelines for secondary prevention strategies.
- Data collection for 3 months or up to 30 consecutive patients in patients with documented CAD/CVD/PAD on a web Case Record Form (CRF) generating warning on the most relevant guideline recommendations, and, when guidelines are not followed, asking the reason for non-adherence.
- Evaluation of the primary and secondary end-points of the study at 6 months after enrollment.
- Second educational intervention to share the results of the first enrollment period of the study focusing the attention on existing gaps between guidelines recommendations and clinical practice.
- New data collection for 3 months or up to 30 consecutive patients in patients with documented CAD/CVD/PAD on a web CRF generating warning on the most relevant guideline recommendations, and, when guidelines are not followed, asking the reason for non-adherence.
- Additional evaluation of the primary and secondary end-points of the study at 6 months after enrollment.
- 12-month follow-up for all patients included in both enrolment phases.
- Medical subject headings
- Myocardial Ischemia, Cerebrovascular Disorders, Peripheral Arterial Disease
What is being measured
The primary outcome is the main question the study is designed to answer.
Adherence to guideline for cholesterol level
Rate of patients at goal for LDL cholesterol (<55 mg/dL)
Measured: 6 months
Secondary outcomes (1)
Adherence to guideline for other risk factors
Rate of patients at goal for BP (SBP/DBP < 130/80 mmHg) and at goal for HbA1c (<7%) as well as rate of overweight patients (BMI > 27 kg/m2) who show a weight loss of at least 10%
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Feb 2024
- Study start15 Sep 2023
- Primary completion30 Jun 2026 (estimated)
- Study completion30 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Ischemic Heart DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 6,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Heart Care Foundation
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06275113
- Sponsor's protocol ID
- K25
- Status last verified
- Feb 2024
- First submitted
- 6 Feb 2024
- Last updated
- 23 Feb 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Colivicchi F, Temporelli PL, Fattirolli F, Abrignani MG, Alonzo A, Arca M, Averna M, Bertoli D, Calabro P, Calo L, Carugo S, Catapano AL, Ceseri M, Di Fusco SA, Di Lenarda A, Fabbri G, Gulizia MM, La Rosa G, Lucci D, Maffei S, Navazio A, Oliva F, Orso F, Riccio C, Scelza N, Gabrielli D, Maggioni AP; BRING-UP Prevention. Sustainable and effective lipid-lowering management: prevention strategies from the BRING-UP prevention study. Eur Heart J Qual Care Clin Outcomes. 2026 Jun 23;12(4):632-643. doi: 10.1093/ehjqcco/qcag021.
PubMed 41655227
Study at a glance
From the registry record, last updated by the sponsor on 23 Feb 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- BRING-UP Prevention
- ClinicalTrials.gov ID
- NCT06275113
- Acronym / sponsor ID
- K25
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 6,000 participants (estimated)
- Lead sponsor
- Heart Care FoundationUniversity, hospital or other
- Study start
- 15 Sep 2023 (actual)
- Primary completion
- 30 Jun 2026 (estimated)
- Study completion
- 30 Jun 2026 (estimated)
- First posted
- 23 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this observational study is to assess in patients with a documented athero-thrombotic event: coronary artery disease (CAD), cerebrovascular disease (CVD), peripheral artery disease (PAD):
- the level of adherence to guideline recommendations with the assumption to improve the rate of patients at goal for cholesterol levels.
- the level of adherence to guideline recommendations and the rate of patients at goal for the other relevant and modifiable risk factors for cardiovascular event recurrence.
Detailed description
Observational, prospective, multicenter study conducted in a large, representative sample of Italian cardiology centers.
Phases:
- First educational intervention to discuss the recommendations of guidelines for secondary prevention strategies.
- Data collection for 3 months or up to 30 consecutive patients in patients with documented CAD/CVD/PAD on a web Case Record Form (CRF) generating warning on the most relevant guideline recommendations, and, when guidelines are not followed, asking the reason for non-adherence.
- Evaluation of the primary and secondary end-points of the study at 6 months after enrollment.
- Second educational intervention to share the results of the first enrollment period of the study focusing the attention on existing gaps between guidelines recommendations and clinical practice.
- New data collection for 3 months or up to 30 consecutive patients in patients with documented CAD/CVD/PAD on a web CRF generating warning on the most relevant guideline recommendations, and, when guidelines are not followed, asking the reason for non-adherence.
- Additional evaluation of the primary and secondary end-points of the study at 6 months after enrollment.
- 12-month follow-up for all patients included in both enrolment phases.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients discharged (after ordinary hospitalisation or day hospital) or managed as outpatients with a documented prior athero-thrombotic event: coronary artery disease (CAD), cerebrovascular disease (CVD), peripheral artery disease (PAD).
Key inclusion criteria (9 listed)
- Both sexes at birth, age ≥18 years
- Documented CAD defined as:
- Documented PAD (previous peripheral bypass surgery or angioplasty, limb or foot amputation, intermittent claudication with objective evidence of peripheral artery disease, Ankle Brachial Index (ABI)<90).
- Documented CVD: Ischemic stroke, previous carotid vascular interventions.
- Signed informed consent.
Key exclusion criteria (3 listed)
- Active neoplasia or very severe disease compromising short-medium term life expectancy.
- Participation in interventional studies.
- Patients already enrolled into the study from another participating center or in the previous enrolling phase.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Adherence to guideline for cholesterol level
Time frame: 6 months
Rate of patients at goal for LDL cholesterol (<55 mg/dL)
1 secondary outcome
Adherence to guideline for other risk factors
Time frame: 6 months
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Feb 2024.
- Derived from this study: PubMed 41655227Colivicchi F, Temporelli PL, Fattirolli F, Abrignani MG, Alonzo A, Arca M, Averna M, Bertoli D, Calabro P, Calo L, Carugo S, Catapano AL, Ceseri M, Di Fusco SA, Di Lenarda A, Fabbri G, Gulizia MM, La Rosa G, Lucci D, Maffei S, Navazio A, Oliva F, Orso F, Riccio C, Scelza N, Gabrielli D, Maggioni AP; BRING-UP Prevention. Sustainable and effective lipid-lowering management: prevention strategies from the BRING-UP prevention study. Eur Heart J Qual Care Clin Outcomes. 2026 Jun 23;12(4):632-643. doi: 10.1093/ehjqcco/qcag021.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
196 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Ischemic Heart Disease and Cerebrovascular Disorders, run by Heart Care Foundation at 196 sites in Italy.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 23 Feb 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 196 sites in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Furio Colivicchi, MD (055/5101361, bringup.prevenzione@heartcarefoundation.it), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Adherence to guideline for cholesterol level (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06275113, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Feb 2024.