MobilizationNCT06280365
MWM Technique in Patients With Knee OA
A study testing Mulligan Mobilization with Movement Technique in people with Mobilization, run by Okan University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to investigate the effect of the MWM technique on pain, normal joint movement, proprioception and quality of life in patients with knee osteoarthritis (OA). Read more about this study
- Who is it for?
- Ages 25 to 65 years
- Conditions the study is for
- Mobilization
- What is being tested?
- Mulligan Mobilization with Movement Technique
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 6 May 2024to 30 Jul 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- being diagnosed with knee osteoarthritis,
- being diagnosed with knee OA at the earliest 6 months ago
Who cannot join
- Participants who were pregnant,
- had knee surgery, had an infection,
- had a pacemaker, had an infraction,
- had cancer, or were receiving corticosteroid treatment were excluded from the study
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Mulligan Mobilization With Movement (MWM) Technique in Patients With Knee Osteoarthritis
The aim of this study is to investigate the effect of the MWM technique on pain, normal joint movement, proprioception and quality of life in patients with knee osteoarthritis (OA).
Read the detailed description
The aim of this study is to investigate the effect of the MWM technique on pain, normal joint movement, muscle strength, proprioception, mobility, balance, functionality and quality of life in patients with knee OA.
- Conditions
- Mobilization
- Being tested
- Mulligan Mobilization with Movement Technique
- Keywords
- Knee Osteoarthritis, Mobilization, Proprioception, Pain
- Medical subject headings
- Osteoarthritis, Knee, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mulligan Mobilization with Movement TechniqueOther
Mobilization Technique
| Study group | Role | What they receive |
|---|---|---|
| MWM group | Experimental | Participants in group 2 will receive MWM technique treatment 3 times a week for 4 weeks. The patient should lie face down with a pillow over the knee and the physiotherapist should stand on the contralateral side for the application. The physiotherapist passes the belt around the waist to the patient's tibia edge. The knee is stabilized with one hand while the leg is supported with the other hand. The knee is moved medially without applying too much force through the belt and the patient is asked to stretch. If there is no pain, the movement is indicated. If pain occurs during the movement, the same procedure is performed for the lateral side by changing the position. It is important that the arch remains horizontal and does not cause rotation of the hip. The movement will be repeated 3 times at the point where there is no pain. Receives: Other: Mulligan Mobilization with Movement Technique |
| Control Group | No intervention | Participants in group 1 will receive conservative treatment 3 times a week for 4 weeks. Conservative treatment includes hot packs and traditional transcutaneous electrical nerve stimulation (TENS), an electrotherapy. All participants in the study will receive 20 minutes of hot pack application to the knee area each session by a physiotherapist. All participants in the study will receive TENS for 20 minutes each session from the physiotherapist, who will place personalized electrodes around the knee joint and adjust the current to the level the person can tolerate. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual Analog Scale (VAS)
VAS, which digitizes parameter values that cannot be measured numerically, was used to evaluate the pain intensity of the participants. The two extreme values of the parameter to be measured are written on the scale as 0 and 10. The person is asked to mark the value that best suits him/her on the scale. For pain, no pain and very severe pain; It is specified as 0 and 10. The person chooses a value according to his/her pain
Measured: 4 week change in pain intensity
Short form-36 (SF-36)
SF-36, developed in 1992, consists of 36 items providing measurement to the following 8 dimensions: physical functioning (10 items), social functioning (2 items), role limitations due to physical problems (4 items), role limitations due to emotional problems (3 items), mental health (5 items), energy/vitality (4 items), pain (2 items), and general health perception (5 items). An increase in the score indicates a higher rate of improvement in health status.
Measured: 4-week change in quality of life
Western Ontario and Mcmaster Universities Osteoarthritis Index (WOMAC)
This survey is conducted to evaluate how much the routine activities in the participants' lives are affected by the knee problem. The survey included the following parameters: pain, physical function, and stiffness. A Likert system ranging from 1 to 5 is used. As the value increases, the intensity of the parameters increases
Measured: 4-week
Evaluation of proprioception
To assess the participants' sense of proprioception, the method of actively reproducing the passive position without supporting the limb was used. In this assessment, where the angle is measured with a goniometer, the person closes their eyes. The limb is passively moved to the target angle and the person is asked to concentrate on the position. After 10 seconds, the starting point of the movement is returned. The person tries to find the target angle by actively moving the same limb. If the angle achieved at the end of the movement is different from the target angle, the difference is recorded as the deviation angle (used to 15° and 45° knee flexion).
Measured: 4-week change in proprioception
The range of motion
A goniometer (Baseline plastic goniometer), which provides numerical and objective results, was used to measure the range of motion of the participants. Knee flexion for normal range of motion in the knee region and knee extension angles were evaluated.
Measured: 4-week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Feb 2024
- Study start6 May 2024
- Primary completion30 Jul 2024
- Study completion30 Jul 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for MobilizationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Okan University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Emine Atıcı, Okan University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06280365
- Sponsor's protocol ID
- 012
- Status last verified
- Jul 2024
- First submitted
- 5 Feb 2024
- Last updated
- 1 Aug 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 1 Aug 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Mulligan Mobilization With Movement (MWM) Technique in Patients With Knee Osteoarthritis
- ClinicalTrials.gov ID
- NCT06280365
- Acronym / sponsor ID
- 012
- Conditions
- Mobilization
- Keywords
- Knee Osteoarthritis, Mobilization, Proprioception, Pain
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Okan UniversityUniversity, hospital or other
- Study start
- 6 May 2024 (actual)
- Primary completion
- 30 Jul 2024 (actual)
- Study completion
- 30 Jul 2024 (actual)
- First posted
- 28 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate the effect of the MWM technique on pain, normal joint movement, proprioception and quality of life in patients with knee osteoarthritis (OA).
Detailed description
The aim of this study is to investigate the effect of the MWM technique on pain, normal joint movement, muscle strength, proprioception, mobility, balance, functionality and quality of life in patients with knee OA.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| MWM group | Experimental | Other: Mulligan Mobilization with Movement TechniqueParticipants in group 2 will receive MWM technique treatment 3 times a week for 4 weeks. The patient should lie face down with a pillow over the knee and the physiotherapist should stand on the contralateral side for the application. The physiotherapist passes the belt around the waist to the patient's tibia edge. The knee is stabilized with one hand while the leg is supported with the other hand. The knee is moved medially without applying too much force through the belt and the patient is asked to stretch. If there is no pain, the movement is indicated. If pain occurs during the movement, the same procedure is performed for the lateral side by changing the position. It is important that the arch remains horizontal and does not cause rotation of the hip. The movement will be repeated 3 times at the point where there is no pain. |
| Control Group | No intervention | –Participants in group 1 will receive conservative treatment 3 times a week for 4 weeks. Conservative treatment includes hot packs and traditional transcutaneous electrical nerve stimulation (TENS), an electrotherapy. All participants in the study will receive 20 minutes of hot pack application to the knee area each session by a physiotherapist. All participants in the study will receive TENS for 20 minutes each session from the physiotherapist, who will place personalized electrodes around the knee joint and adjust the current to the level the person can tolerate. |
Who may qualify
- Ages
- 25 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- being diagnosed with knee osteoarthritis,
- being diagnosed with knee OA at the earliest 6 months ago
Key exclusion criteria (4 listed)
- Participants who were pregnant,
- had knee surgery, had an infection,
- had a pacemaker, had an infraction,
- had cancer, or were receiving corticosteroid treatment were excluded from the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mulligan Mobilization with Movement TechniqueMobilization Technique | Other | MWM group |
Primary outcome
Visual Analog Scale (VAS)
Time frame: 4 week change in pain intensity
VAS, which digitizes parameter values that cannot be measured numerically, was used to evaluate the pain intensity of the participants. The two extreme values of the parameter to be measured are written on the scale as 0 and 10. The person is asked to mark the value that best suits him/her on the scale. For pain, no pain and very severe pain; It is specified as 0 and 10. The person chooses a value according to his/her pain
Short form-36 (SF-36)
Time frame: 4-week change in quality of life
SF-36, developed in 1992, consists of 36 items providing measurement to the following 8 dimensions: physical functioning (10 items), social functioning (2 items), role limitations due to physical problems (4 items), role limitations due to emotional problems (3 items), mental health (5 items), energy/vitality (4 items), pain (2 items), and general health perception (5 items). An increase in the score indicates a higher rate of improvement in health status.
Western Ontario and Mcmaster Universities Osteoarthritis Index (WOMAC)
Time frame: 4-week
This survey is conducted to evaluate how much the routine activities in the participants' lives are affected by the knee problem. The survey included the following parameters: pain, physical function, and stiffness. A Likert system ranging from 1 to 5 is used. As the value increases, the intensity of the parameters increases
Evaluation of proprioception
Time frame: 4-week change in proprioception
To assess the participants' sense of proprioception, the method of actively reproducing the passive position without supporting the limb was used. In this assessment, where the angle is measured with a goniometer, the person closes their eyes. The limb is passively moved to the target angle and the person is asked to concentrate on the position. After 10 seconds, the starting point of the movement is returned. The person tries to find the target angle by actively moving the same limb. If the angle achieved at the end of the movement is different from the target angle, the difference is recorded as the deviation angle (used to 15° and 45° knee flexion).
The range of motion
Time frame: 4-week
A goniometer (Baseline plastic goniometer), which provides numerical and objective results, was used to measure the range of motion of the participants. Knee flexion for normal range of motion in the knee region and knee extension angles were evaluated.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Aug 2024.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mulligan Mobilization with Movement Technique in people with Mobilization, run by Okan University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 1 Aug 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual Analog Scale (VAS) (time frame: 4 week change in pain intensity). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Aug 2024.