Postoperative Acute Kidney InjuryNCT06296108
Risk Factors for Acute Kidney Injury in Patients Undergoing Arthroplasty
An observational study of Postoperative Acute Kidney Injury and Arthroplasty, run by Ankara University at 1 site in Turkey (Türkiye).
Trial summary
The authors aimed to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Postoperative Acute Kidney Injury, Arthroplasty
- What is being tested?
- acute kidney injury
- How many people
- 911 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jun 2022to 31 Dec 2022
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients aged above 18 years old undergoing arthroplasty surgery
Who may be able to join
- Patients aged above 18 years old undergoing arthroplasty surgery
Who cannot join
- Known acute renal failure or chronic renal failure
- Patients aged below 18 years old
- Patients refusing to participate to the study
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Ankara University Medical School Anesthesiology and ICU Department
Ankara
About this study
Official title: Risk Factors for Acute Kidney Injury in Patients Undergoing Total Joint Arthroplasty
The authors aimed to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty.
Read the detailed description
Aim: The primary aim of the current study is to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty. Considering that this patient group is mostly composed of advanced age and comorbid patients, the secondary aim of the study is to identify risky patients with predictable risk factors and to chart a way to make preoperative optimizations of the patients before developing postoperative complications.
Materials and Methods: Patients who underwent joint arthroplasty between 2015 and 2020 in Ankara University Faculty of Medicine, Department of Orthopedics and Traumatology were included. Within the scope of the study, patients' gender, age, weight, height, body mass index values, smoking, American Society of Anesthesiologist (ASA) score, Charlson-Comorbidity Index score (CCI), type of operation, duration of surgery, presence of intraoperative hypotension, anesthesia method , diabetes, hypertension, coronary artery disease, presence of congestive heart failure, presence of preoperative anemia, preoperative uric acid and albumin level, use of nephrotoxic agents in the perioperative period, basal creatinine and glomerular filtration rate (GFR) values, platelet suspension in the perioperative period, erythrocyte suspension, Amounts of fresh frozen plasma transfusions, postoperative creatinine at 24 hours - 48 hours - discharge, GFR values and Kidney Disesae Improving Global Outcomes (KDIGO) scores, length of hospital stay and length of stay in the intensive care unit were evaluated.
- Conditions
- Postoperative Acute Kidney Injury, Arthroplasty
- Being tested
- acute kidney injury
- Keywords
- arthroplasty, acute kidney injury
- Medical subject headings
- Acute Kidney Injury
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
acute kidney injuryOther
The incidence of acute kidney injury was determined in patients included to the study
What is being measured
The primary outcome is the main question the study is designed to answer.
Acute kidney injury in patients undergoing arthroplasty surgery
To determine the incidence of acute kidney injury in patients undergoing arthroplasty surgery
Measured: Retrospective between 2015-2020
Secondary outcomes (1)
Risk factors causing acute kidney injury in patients undergoing arthroplasty surgery
To determine the risk factors causing acute kidney injury in patients undergoing arthroplasty surgery
Measured: Retrospective between 2015-2020
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Mar 2024
- Study start1 Jun 2022
- Primary completion31 Dec 2022
- Study completion31 Dec 2022
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative Acute Kidney InjuryStudies of the same condition, open and under way.
- More trials run by Ankara UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 911 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ankara University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sanem Cakar Turhan, Ankara University
- Investigators
- Sanem Çakar Turhan, Assoc. Prof., Study chair, Ankara University Medical School, Department of Anesthesiology and ICUHazal Nur Tezel Kılıc, Specialist, Principal investigator, Ankara University Medical School, Department of Anesthesiology and ICUSuheyla Karadag Erkoc, Assoc. Prof., Principal investigator, Ankara University Medical School, Department of Anesthesiology and ICUHakan Kocaoglu, Assoc. Prof., Principal investigator, Ankara University Medical School, Department of Orthopedics and Traumatology Surgery
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06296108
- Sponsor's protocol ID
- I05-310-22
- Status last verified
- Mar 2024
- First submitted
- 26 Feb 2024
- Last updated
- 6 Mar 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Mar 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Risk Factors for Acute Kidney Injury in Patients Undergoing Total Joint Arthroplasty
- ClinicalTrials.gov ID
- NCT06296108
- Acronym / sponsor ID
- I05-310-22
- Conditions
- Postoperative Acute Kidney Injury, Arthroplasty
- Keywords
- arthroplasty, acute kidney injury
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 911 participants (actual)
- Lead sponsor
- Ankara UniversityUniversity, hospital or other
- Study start
- 1 Jun 2022 (actual)
- Primary completion
- 31 Dec 2022 (actual)
- Study completion
- 31 Dec 2022 (actual)
- First posted
- 6 Mar 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The authors aimed to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty.
Detailed description
Aim: The primary aim of the current study is to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty. Considering that this patient group is mostly composed of advanced age and comorbid patients, the secondary aim of the study is to identify risky patients with predictable risk factors and to chart a way to make preoperative optimizations of the patients before developing postoperative complications.
Materials and Methods: Patients who underwent joint arthroplasty between 2015 and 2020 in Ankara University Faculty of Medicine, Department of Orthopedics and Traumatology were included. Within the scope of the study, patients' gender, age, weight, height, body mass index values, smoking, American Society of Anesthesiologist (ASA) score, Charlson-Comorbidity Index score (CCI), type of operation, duration of surgery, presence of intraoperative hypotension, anesthesia method , diabetes, hypertension, coronary artery disease, presence of congestive heart failure, presence of preoperative anemia, preoperative uric acid and albumin level, use of nephrotoxic agents in the perioperative period, basal creatinine and glomerular filtration rate (GFR) values, platelet suspension in the perioperative period, erythrocyte suspension, Amounts of fresh frozen plasma transfusions, postoperative creatinine at 24 hours - 48 hours - discharge, GFR values and Kidney Disesae Improving Global Outcomes (KDIGO) scores, length of hospital stay and length of stay in the intensive care unit were evaluated.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients aged above 18 years old undergoing arthroplasty surgery
Key inclusion criteria (1 listed)
- Patients aged above 18 years old undergoing arthroplasty surgery
Key exclusion criteria (3 listed)
- Known acute renal failure or chronic renal failure
- Patients aged below 18 years old
- Patients refusing to participate to the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| acute kidney injuryThe incidence of acute kidney injury was determined in patients included to the study | Other | – |
Primary outcome
Acute kidney injury in patients undergoing arthroplasty surgery
Time frame: Retrospective between 2015-2020
To determine the incidence of acute kidney injury in patients undergoing arthroplasty surgery
1 secondary outcome
Risk factors causing acute kidney injury in patients undergoing arthroplasty surgery
Time frame: Retrospective between 2015-2020
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Mar 2024.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Sanem Çakar Turhan, Assoc. Prof. study chair
Ankara University Medical School, Department of Anesthesiology and ICU
Hazal Nur Tezel Kılıc, Specialist principal investigator
Ankara University Medical School, Department of Anesthesiology and ICU
Suheyla Karadag Erkoc, Assoc. Prof. principal investigator
Ankara University Medical School, Department of Anesthesiology and ICU
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Postoperative Acute Kidney Injury and Arthroplasty, run by Ankara University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Mar 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Acute kidney injury in patients undergoing arthroplasty surgery (time frame: Retrospective between 2015-2020). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Mar 2024.