Influenza VaccinationNCT06300242
Incentives for Influenza Vaccination
A study testing Reminders and Financial Incentive in people with Influenza Vaccination, run by University of Southern California at 1 site in United States.
Trial summary
In this work, we are assessing the impact of messaging with or without a $50 financial incentive on influenza vaccination rates in a county health system. Our main hypothesis is that a message with a $50 financial incentive will increase vaccination rates relative to a control/"treatment as usual" group. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Influenza Vaccination
- What is being tested?
- Reminders and Financial Incentive
- Type of treatment
- Vaccines, Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 69,972 participants
- Where
- 1 siteUnited States
- Study dates
- 17 Jan 2024to 29 Feb 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Ages 18 and over
- Empaneled patients or non-empaneled patients with a primary care visit in past 18 months with valid insurance
- Due for an annual flu shot according to the electronic medical record
- Active phone number or email
- Do not have "Do not contact" flag
Who cannot join
- Under age 18
- Received an annual flu shot based on medical record
Trial locations and contacts
1 site in 1 country.
United States1 site
Contra Costa Health Services
Martinez, California, 94553
About this study
Official title: Financial Incentives for Influenza Vaccination
In this work, we are assessing the impact of messaging with or without a $50 financial incentive on influenza vaccination rates in a county health system. Our main hypothesis is that a message with a $50 financial incentive will increase vaccination rates relative to a control/"treatment as usual" group. We further hypothesize that the financial incentive will increase vaccination rates relative to the message only arm.
- Conditions
- Influenza Vaccination
- Being tested
- Reminders, Financial Incentive, Placebo
- Medical subject headings
- Influenza, Human
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
RemindersBehavioural
Reminders
Financial IncentiveBehavioural
$50 financial incentive for getting vaccinated within 1-week
PlaceboOther
No special messages or incentives
| Study group | Role | What they receive |
|---|---|---|
| Message Only | Experimental | Patients sent an email or SMS reminding them to get vaccinated against the flu. Receives: Behavioral: Reminders |
| Message + Financial Incentive | Experimental | Patients sent an email or SMS reminding them to get vaccinated against the flu and offering them a $50 financial incentive if they are vaccinated within 1-week. Receives: Behavioral: Reminders; Behavioral: Financial Incentive |
| Active Control | Active comparator | Patients not sent any reminder message. Receives: Other: Placebo |
What is being measured
The primary outcome is the main question the study is designed to answer.
Vaccination status at 1 week
influenza vaccination status as documented in the EMR and from the California Immunization Registry (CAIRS)
Measured: 1 week
Secondary outcomes (2)
Vaccination status at 2 weeks
Influenza vaccination status as documented in the EMR and from the California Immunization Registry (CAIRS)
Measured: 2 weeks
Vaccination status at 1 month
Influenza vaccination status as documented in the EMR and from the California Immunization Registry (CAIRS)
Measured: 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Mar 2024
- Study start17 Jan 2024
- Primary completion24 Jan 2024
- Study completion29 Feb 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Influenza VaccinationStudies of the same condition, open and under way.
- More trials run by University of Southern CaliforniaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 69,972 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Southern California
- Sponsor type
- University, hospital or other
- Collaborators
- J-PAL North America
- Responsible party
- Principal investigator, Mireille Jacobson, University of Southern California
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06300242
- Sponsor's protocol ID
- UP-23-00859
- Status last verified
- May 2024
- First submitted
- 28 Feb 2024
- Last updated
- 13 May 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Will be shared with qualified researchers upon request.
Publications
Chang TY, Jacobson M, Shah M, Pramanik R, Shah SB. Impact of reminder messages, with and without financial incentives, on influenza vaccination: A randomized trial in a California health system. Vaccine. 2026 Mar 7;75:128263. doi: 10.1016/j.vaccine.2026.128263. Epub 2026 Jan 27.
PubMed 41604808
Study at a glance
From the registry record, last updated by the sponsor on 13 May 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Financial Incentives for Influenza Vaccination
- ClinicalTrials.gov ID
- NCT06300242
- Acronym / sponsor ID
- UP-23-00859
- Conditions
- Influenza Vaccination
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 69,972 participants (actual)
- Lead sponsor
- University of Southern CaliforniaUniversity, hospital or other
- Collaborators
- J-PAL North America
- Study start
- 17 Jan 2024 (actual)
- Primary completion
- 24 Jan 2024 (actual)
- Study completion
- 29 Feb 2024 (actual)
- First posted
- 8 Mar 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In this work, we are assessing the impact of messaging with or without a $50 financial incentive on influenza vaccination rates in a county health system. Our main hypothesis is that a message with a $50 financial incentive will increase vaccination rates relative to a control/"treatment as usual" group. We further hypothesize that the financial incentive will increase vaccination rates relative to the message only arm.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Message Only | Experimental | Behavioral: RemindersPatients sent an email or SMS reminding them to get vaccinated against the flu. |
| Message + Financial Incentive | Experimental | Behavioral: Reminders, Behavioral: Financial IncentivePatients sent an email or SMS reminding them to get vaccinated against the flu and offering them a $50 financial incentive if they are vaccinated within 1-week. |
| Active Control | Active comparator | Other: PlaceboPatients not sent any reminder message. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Ages 18 and over
- Empaneled patients or non-empaneled patients with a primary care visit in past 18 months with valid insurance
- Due for an annual flu shot according to the electronic medical record
- Active phone number or email
- Do not have "Do not contact" flag
Key exclusion criteria (2 listed)
- Under age 18
- Received an annual flu shot based on medical record
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| RemindersReminders | Behavioural | Message + Financial Incentive, Message Only |
| Financial Incentive$50 financial incentive for getting vaccinated within 1-week | Behavioural | Message + Financial Incentive |
| PlaceboNo special messages or incentives | Other | Active Control |
Primary outcome
Vaccination status at 1 week
Time frame: 1 week
influenza vaccination status as documented in the EMR and from the California Immunization Registry (CAIRS)
2 secondary outcomes
Vaccination status at 2 weeks
Time frame: 2 weeks
Vaccination status at 1 month
Time frame: 1 month
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 May 2024.
- Derived from this study: PubMed 41604808Chang TY, Jacobson M, Shah M, Pramanik R, Shah SB. Impact of reminder messages, with and without financial incentives, on influenza vaccination: A randomized trial in a California health system. Vaccine. 2026 Mar 7;75:128263. doi: 10.1016/j.vaccine.2026.128263. Epub 2026 Jan 27.
- Individual participant dataSharing planned: Yes. Will be shared with qualified researchers upon request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Reminders and Financial Incentive in people with Influenza Vaccination, run by University of Southern California at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 May 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Vaccination status at 1 week (time frame: 1 week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06300242, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 May 2024.