AzTrials
AzTrials

Acute Coronary SyndromeEYESHOT-2NCT06316128

EmploYEd Antithrombotic Therapies in Patients With Acute Coronary Syndromes HOspitalized in iTalian CCUs

An observational study of Acute Coronary Syndrome, run by Heart Care Foundation at 189 sites in Italy.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This registry has the aim to assess the use of different antithrombotic therapies, including untested drug combinations, routinely used during the hospitalization phase, with their timing, route and dose of administration, in consecutive patients discharged with a diagnosis NSTEMI or STEMI in Italian Cardiac care… Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Acute Coronary Syndrome
How many people
2,806 participants
Where
189 sitesItaly
Study dates
1 Feb 2024to 15 Mar 2024
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • Adult, Older adult

Study population: All consecutive patients, who met the eligibility criteria, admitted in hospitals with or without cardiac catheterization laboratories and cardiac surgery facilities during a period of 4 weeks.

Who may be able to join

  • All consecutive patients aged 18 years or more, discharged with diagnosis of myocardial infarction (NSTEMI or STEMI) admitted to CCUs undergoing myocardial revascularization (PCI or CABG) or conservative treatment. At presentation, the diagnosis of NSTEMI will be based on the measurement of troponins and assessment of ECG changes, as suggested by European Society of Cardiology (ESC) guidelines; the diagnosis of STEMI will be characterized by an acute chest pain and persistent (>20 min) ST-segment elevation ≥ 1mm in two or more limb leads, or contiguous pre-cordial leads or left bundle branch block.
  • Written informed consent signed. Patients who cannot provide the informed consent due to very severe clinical conditions can give their consent some hours/days after admission, when more favourable clinical conditions allow them to receive the appropriate information. Patients having died before giving informed consent may also be included unless the local Institutional Review Board (IRB) does not allow this procedure. In that case, it is strongly suggested to obtain relative(s) agreement through the collect of a signed informed consent.

Who cannot join

  • Patients with a diagnosis of Unstable Angina,
  • Patients developing MI after PCI or CABG,
  • MI following non-cardiac surgery or traumatic causes,
  • Patients with chest pain without elevation of troponin,
  • Patients enrolled in Randomized Controlled Trial (RCTs),
  • Patients already enrolled into the study from another CCU

Trial locations and contacts

189 sites in 1 country.

189 sites in 1 country

Italy189 sites

  • Ospedale Miulli - U.O.C. Cardiologia - Utic

    Acquaviva delle Fonti, BA, 70021

  • Ospedale Della Murgia - Fabio Perinei - S.C. Cardiologia-Utic

    Altamura, BA, 70022

  • Ospedali Riuniti - Sod Cardiologia Ospedaliera E Utic

    Ancona, AN, 60122

  • Irccs Inrca - Uo Cardiologia/Utic/Telecardiologia

    Ancona, AN, 60131

  • Ospedale San Donato - U.O.C Cardiologia

    Arezzo, AR, 52100

  • Ospedale Dei Castelli - U.O.C. Di Cardiologia E Utic

    Ariccia, RM, 00072

  • Ospedale Civile - U.O.C. Di Cardiologia

    Arzignano, VI, 36071

  • Ospedale E. Muscatello - U.O. Di Cardiologia - Utic

    Augusta, SR, 96011

  • Aorn San Giuseppe Moscati - U.O. Cardiologia/Utic 'D. Rotiroti'

    Avellino, AV, 83100

  • Presidio Ospedaliero Moscati - U.O.C. Cardiologia-Utic

    Aversa, CE, 81031

  • Ospedale G. Di Maria - Cardiologia Utic

    Avola, SR, 96012

  • Ospedale Santa Maria Annunziata - Sos Cardiologia Clinica

    Bagno a Ripoli, FI, 50011

  • Ospedale San Paolo - Cardiologia-Utic

    Bari, BA, 70123

  • Aou Policlinico - Uoc Cardiologia Ospedaliera

    Bari, BA, 70124

  • Ospedale Di Bentivoglio - U.O. Cardiologia Pianura

    Bentivoglio, BO, 40010

  • Humanitas Gavazzeni - U.O. Cardiologia

    Bergamo, MI, 24125

  • Ospedale Maggiore - U.O.C. Di Cardiologia

    Bologna, BO, 40133

  • Ospedale Policlinico S. Orsola-Malpighi - U.O. Cardiologia-Galie'

    Bologna, BO, 40138

  • Ospedale Centrale Bolzano - Cardiologia E Prove Funzionali

    Bolzano, BZ, 39100

  • Ospedale Ss. Trinita' - S.C. Di Cardiologia

    Borgomanero, 28021

  • Ospedale Civile Di Boscotrecase - Utic Cardiologia

    Boscotrecase, 80042

  • Asst Spedali Civili - Cardiologia

    Brescia, BS, 25123

  • Ospedale Perrino - U.O.C. Di Cardiologia

    Brindisi, BR, 72100

  • Arnas G. Brotzu - Cardiologia Con Utic

    Cagliari, CA, 09134

  • Nuovo Ospedale Versilia - Sc Cardiologia

    Camaiore, LU, 55041

  • Ospedale A. Cardarelli - U.O. Cardiologia E Utic

    Campobasso, CB, 86100

  • Ospedale Di Venere - U.O.C. Di Cardiologia

    Carbonara di Bari, BA, 70012

  • Ospedale Santo Spirito - Sc Cardiologia

    Casale, AL, 15033

  • Azienda Ospedaliera S. Anna E S. Sebastiano - U.O. Cardiologia D'Emergenza Con Utic

    Caserta, CE, 81100

  • Ospedale San Leonardo - U.O. Di Cardiologia-Utic

    Castellammare di Stabia, 80053

  • Ospedale Di Castellaneta - S.C. Cardiologia

    Castellaneta, TA, 74011

  • Ospedale Santa Croce - Uosd Cardiologia E Di Continuita Assist.

    Castelnuovo di Garfagnana, LU, 55032

  • P.O. "Pugliese" - A.O.U. "Renato Dulbecco" - Utic-Emodinamica E Cardiologia Interventistica

    Catanzaro, CZ, 88100

  • Ospedale S. Maria Incoronata Dell'Olmo - U.O.C. Cardiologia-Utic

    Cava de' Tirreni, SA, 84013

  • Ospedale Civile Bassa Val Di Cecina - Unita Operativa Di Cardiologia E Utic

    Cecina, LI, 57023

  • Fondazione G. Giglio - U.O. Di Cardiologia

    Cefalù, PA, 90015

  • Ospedale Di Cernusco Sul Naviglio - U. O. Di Cardiologia E Ucc

    Cernusco sul Naviglio, MI, 20063

  • Ospedale M. Bufalini - U.O. Di Cardiologia-Utic

    Cesena, FC, 47521

  • Asst Franciacorta - Presidio Chiari - Cardiologia/Utic

    Chiari, BS, 25032

  • Ospedale Policlinico Ss. Annunziata - Uoc Cardiologia-Utic

    Chieti, CH, 66013

  • Ospedale Civico - Sc Cardiologia

    Chivasso, TO, 10034

  • Ospedale Edoardo Bassini - Sc Cardiologia-Ucc Asst Nord Milano (Bassini-Ssg)

    Cinisello Balsamo, MI, 20092

  • Por Cirie'- Lanzo Presidio Cirie' - S.C. Cardiologia

    Cirié, TO, 10073

  • Presidio Ospedaliero Citta' Di Castello - U.O. Cardiologia/Utic

    Città di Castello, PG, 06012

  • Presidio Osp. Di Civitanova Marche - Sc Cardiologia

    Civitanova Marche, MC, 62012

  • Ospedale Maggiore - U.O. Cardiologia E Utic

    Crema, CR, 26013

  • Azienda Ospedaliera Santa Croce E Carle - Sc Cardiologia

    Cuneo, CN, 12100

  • Ospedale Di Desenzano Del Garda - Divisione Di Cardiologia - U.C.C.

    Desenzano del Garda, BS, 25015

  • Ospedale Pio Xi - U.O.C. Di Cardiologia

    Desio, MB, 20832

  • Ospedale San Biagio - Soc Cardiologia Vco

    Domodossola, VB, 28845

  • Ospedale Maria Ss. Addolorata - U.O. Di Cardiologia Utic

    Eboli, SA, 84025

  • Ospedale San Giuseppe - Cardiologia

    Empoli, FI, 50053

  • Po S. Antonio Abate Di Trapani - U.O.C. Di Cardiologia, Utic Ed Emodinamica

    Erice, TP, 91016

  • Presidio Ospedaliero "Santa Maria Del Prato" - U.O.C. Di Cardiologia-Utic

    Feltre, BL, 32032

  • Arcispedale Sant'Anna - U.O. Cardiologia

    Ferrara, FE, 44124

  • Ospedale Civile - U.O.C. Cardiologia - Utic

    Fidenza, PR, 43036

  • Ospedale Santa Maria Nuova - Cardiologia

    Florence, FI, 50122

  • Aou Careggi - Interventistica Cardiologica Strutturale

    Florence, FI, 50134

  • Policlinico Riuniti - S.C. Di Cardiologia Universitaria-Utic

    Foggia, FG, 71100

  • Nuovo Ospedale San Giovanni Battista - S.C. Cardiologia

    Foligno, PG, 06034

  • Ospedale G.B. Morgagni - L. Pierantoni - U.O. Cardiologia

    Forlì, FC, 47121

  • Ospedale San Giovanni Di Dio - Uo Cardiologia - Utic

    Frattamaggiore, 80027

  • Ospedale Civile 'La Memoria' - U.O. Di Cardiologia

    Gavardo, BS, 25085

  • Ospedale Padre Antero Micone - Sc Cardiologia - Utic

    Genova, GE, 16100

  • Ospedale Villa Scassi - Asl 3 Ligure - Sc Cardiologia Utic

    Genova, GE, 16149

  • Presidio Ospedaliero San Giugliano - U.O. Cardiologia - Utic

    Giugliano in Campania, 80014

  • Ospedale Moriggia Pelascini - Unita' Operativa Di Cardiologia

    Gravedona, CO, 22015

  • Ospedale Civile Di Guastalla - Sos Cardiologia E Riabilitazione Card Area Nord

    Guastalla, RE, 42016

  • Ospedale Gubbio-Gualdo Tadino - U.O. Di Utic E Cardiologia

    Gubbio, PG, 06024

  • Ospedale Civile - S.C. Cardiologia

    Ivrea, Ivrea, 10015

  • Ospedale S. Andrea - S.C. Cardiologia

    La Spezia, SP, 19124

  • Ospedale Anna Rizzoli - Cardiologia-Utic

    Lacco Ameno, 80076

  • Ospedale Del Tigullio Polo Lavagna - Sc Cardiologia E Utic

    Lavagna, GE, 16033

  • Ospedale Vito Fazzi - Uoc Cardiologia-Utic Ed Emodinamica

    Lecce, LE, 73100

  • Asst Ovest Milanese - Po Di Legnano - Cardiologia E Unita' Coronarica

    Legnano, MI, 20025

  • P.O. Lentini - Uosd Di Cardiologia Con Utic

    Lentini, SR, 96016

  • Ospedali Riuniti - U.O.C. Cardiologia E Utic

    Livorno, LI, 57124

  • Ospedale Maggiore Di Lodi - U.O.C. Cardiologia

    Lodi, LO, 26900

  • Ospedale Civile - Uo Servizio Cardiologia

    Lugo, RA, 48022

  • Casa Di Cura San Michele - Uo Cardiologia

    Maddaloni, CE, 81024

  • Ospedale Civile Fornaroli - U.O. Cardiologia

    Magenta, MI, 20013

  • Ospedale Apuane - U.O. Cardiologia-Utic

    Massa, MS, 54100

  • Ospedale Madonna Delle Grazie - Ssd Utic

    Matera, MT, 75100

  • Osp Abele Ajello - U.O.C. Cardiologia Con Utic

    Mazara del Vallo, TP, 91026

  • Ospedale San Leopoldo Mandic - Cardiologia - Ucc

    Merate, LC, 23807

  • Irccs Centro Neurolesi Bonino Pulejo - P.O. Piemonte - Cardiologia E Utic

    Messina, ME, 98124

  • Ospedale Dell'Angelo - U.O.C. Cardiologia

    Mestre, VE, 30171

  • Fondazione Irccs Ca' Granda Ospedale Maggiore Policlinico - Uoc Malattie Cardiovascolari

    Milan, MI, 20122

  • Centro Cardiologico Monzino Irccs - Terapia Intensiva Cardiologica (Utic)

    Milan, MI, 20138

  • Ospedale San Luca Irccs - Istituto Auxologico - Area Critica Cardiologica

    Milan, MI, 20149

  • ASST SANTI PAOLO E CARLO - PO San Carlo - CARDIOLOGIA-UCC

    Milan, MI, 20153

  • Ospedale L. Sacco - Sc Cardiologia

    Milan, MI, 20157

  • Asst Ospedale Metropolitano Niguarda - Cardiologia 1 - Emodinamica

    Milan, MI, 20162

  • Presidio Ospedaliero Di Mirano - U.O.C. Di Cardiologia

    Mirano, VE, 30035

  • Ospedale Civile Di Baggiovara - U.O. Di Cardiologia

    Modena, MO, 41126

  • Ospedale Santa Croce - Cardiologia

    Moncalieri, TO, 10024

  • A.O.U. Cagliari Policlinico Monserrato - Sc Cardiologia Utic Emodinamica

    Monserrato, CA, 09124

  • Ospedale San Valentino - U.O.C. Cardiologia

    Montebelluna, TV, 31044

  • Ospedale Valdarno S. Maria Della Gruccia - U.O. Malattie Cardiovascolari

    Montevarchi, AR, 52027

  • Fondazione Irccs San Gerardo Dei Tintori - Ospedale San Gerardo - U.O.C. Cardiologia

    Monza, MB, 20900

  • Aorn Cardarelli - U.O. Cardiologia Con Utic

    Naples, 80131

  • Aorn Ospedale Dei Colli - P.O. Monaldi - Uoc Cardiologia-Utic

    Naples, 80131

  • Ospedale Dei Pellegrini - Uoc Cardiologia-Utic

    Naples, 80134

  • Ospedale Del Mare - U.O. Cardiologia Con Utic-Emodinamica

    Naples, 80147

  • Presidio Ospedaliero Umberto I - Uoc Cardiologia - Utic

    Nocera Inferiore, SA, 84014

  • Pres. Ospedaliero S. Maria Della Pieta' - U.O. Cardiologia E Utic

    Nola, 80035

  • Aou Maggiore Della Carita' - Scdo Cardiologia Ii

    Novara, 28100

  • Ospedale San Francesco - Cardiologia - Utic

    Nuoro, NU, 08100

  • Ospedale Giovanni Paolo Ii - Utic - Cardiologia

    Olbia, OT, 07026

  • Istituto Clinico San Rocco - Unita' Operativa Di Cardiologia

    Ome, BS, 25050

  • Aou San Luigi Gonzaga - S.C.D.O. Cardiologia

    Orbassano, TO, 10043

  • Aou Policlinico P. Giaccone - U.O.C. Cardiologia

    Palermo, PA, 90127

  • Arnas P.O. Civico E Benfratelli - Uoc Utic

    Palermo, PA, 90127

  • Ospedale G.F. Ingrassia - Cardiologia - Utic

    Palermo, PA, 90129

  • Maria Eleonora Hospital - Cardiologia

    Palermo, PA, 90135

  • Aor Villa Sofia-Cervello P.O. Cervello - U.O. Cardiologia - Cervello

    Palermo, PA, 90146

  • Aor Villa Sofia-Cervello Po Villa Sofia - Uoc Cardiologia E Utic E Emodinamica -Villa Sofia

    Palermo, PA, 90146

  • Azienda Ospedaliera Universitaria Parma - U.O.C. Di Cardiologia

    Parma, PR, 43126

  • Fondazione Irccs Policlinico San Matteo - Uoc Cardiologia 1

    Pavia, PV, 27100

  • Azienda Ospedaliera Di Perugia - S.C. Cardiologia

    Perugia, PG, 06129

  • Presidio Ospedaliero San Salvatore - Cardiologia E Utic

    Pesaro, PU, 61121

  • Ospedale Civile Dello Spirito Santo - Cardiologia Con Utic

    Pescara, PE, 65124

  • Ospedale Ss. Cosma E Damiano - Sos Cardiologia

    Pescia, PT, 51017

  • Ospedale Civile 'Guglielmo Da Saliceto' - Uoc Cardiologia E Utic

    Piacenza, PC, 29100

  • Po Ponente - Ospedale Santa Corona - Sc Cardiologia Ponente

    Pietra Ligure, SV, 17027

  • Ospedale Villamarina - Cardiologia E Utic Piombino Elba

    Piombino, LI, 57025

  • Ftgm - Stabilimento Di Pisa - Cardiologia E Medicina Cardiovascolare

    Pisa, PI, 56124

  • Ospedale San Jacopo - Soc Cardiologia

    Pistoia, PT, 51100

  • Ospedale Dell'Alta Val D'Elsa - Uosd Cardiologia-Utic

    Poggibonsi, SI, 53036

  • Presidio Ospedaliero Luigi Curto - Uo Cardiologia-Utic

    Polla, SA, 84035

  • Ospedale Degli Infermi - Sc Di Cardiologia

    Ponderano, BI, 13875

  • Aor San Carlo - Ospedale San Carlo - Ssd Terapia Intensiva Cardiologica

    Potenza, PZ, 85100

  • Ospedale Santa Maria Delle Grazie - U.O. Cardiologia - Utic Con Emodinamica

    Pozzuoli, 80078

  • Ospedale Santo Stefano - U.O. Cardiologia

    Prato, PO, 59100

  • Ospedale Giovanni Paolo Ii - U.O.C. Cardiologia-Utic

    Ragusa, RG, 97100

  • Ospedale Civile Santa Maria Delle Croci - Uoc Cardiologia

    Ravenna, RA, 48121

  • Grande Ospedale Metropolitano - Osp Riuniti Bianchi Melacrino - Uoc Cardiologia E Utic

    Reggio Calabria, RC, 89124

  • Po Santa Maria Nuova - Ausl Re Irccs - Soc Cardiologia Ospedaliera

    Reggio Emilia, RE, 42100

  • Ospedale Civile - Unita' Operativa Di Cardiologia

    Rho, MI, 20017

  • P.O. San Camillo de Lellis - U.O.C. Cardiologia

    Rieti, RI, 02100

  • Ospedale Infermi - U.O. Cardiologia

    Rimini, RN, 47900

  • Ospedale Degli Infermi - Sc Cardiologia

    Rivoli, TO, 10098

  • European Hospital - U.O.C. Cardiologia Interventistica

    Roma, RM, 00149

  • Ospedale San Camillo - Uoc Cardiologia

    Roma, RM, 00152

  • Ospedale Sandro Pertini - Uoc Cardiologia

    Roma, RM, 00157

  • Aurelia Hospital - U.O.C Cardiologia

    Roma, RM, 00163

  • Policlinico Casilino - U.O.C. Cardiologia

    Roma, RM, 00169

  • Ospedale Madre Giuseppina Vannini - U.O.C. Cardiologia

    Roma, RM, 00177

  • Ospedale Isola Tiberina - Uoc Cardiologia Diagnostica Interventistica-Utic

    Roma, RM, 00188

  • Ospedale Santo Spirito - Uoc Cardiologia

    Roma, RM, 00193

  • Istituto Clinico Humanitas - Irccs - Cardiologia Clinica, Interventistica E Ucc

    Rozzano, MI, 20089

  • Aou S. Giovanni Di Dio-Ruggi D'Aragona - Ssd Utic

    Salerno, SA, 84131

  • Ospedale G. Fracastoro - U.O.C. Di Cardiologia

    San Bonifacio, VR, 37047

  • Ospedale Civile - U.O.C. Di Cardiologia

    San Donà di Piave, VE, 30027

  • Irccs Policlinico San Donato - U.O. Cardiologia Con Utic

    San Donato Milanese, MI, 20097

  • Ospedale Nostra Signora Di Bonaria - U.O.C. Cardiologia E Utic

    San Gavino Monreale, SU, 09037

  • Ospedale Casa Sollievo Della Sofferenza - Cardiologia - Utic - Riabil Cardiologica

    San Giovanni Rotondo, FG, 71013

  • Presidio Ospedaliero - U.O. Cardiologia

    Sanremo, IM, 18038

  • Ospedale San Giuseppe E Melorio - U.O.C. Cardiologia Utic

    Santa Maria Capua Vetere, CE, 81055

  • Presidio Ospedaliero Di Saronno - U.O.C. Di Cardiologia

    Saronno, VA, 21047

  • Ospedale Ss. Annunziata - Cardiologia Clinica Ed Interventistica

    Sassari, SS, 07100

  • Ospedale Di Sassuolo - Cardiologia

    Sassuolo, MO, 41049

  • P.O. Levante - Ospedale San Paolo - S.C. Cardiologia Levante

    Savona, SV, 17100

  • Ospedale Ignazio Veris Delli Ponti - Uoc Cardiologia-Utic "E. Vilei"

    Scorrano, LE, 73020

  • Ospedale Bolognini - Cardiologia E Unita' Coronarica

    Seriate, BG, 24068

  • Presidio Ospedaliero San Rocco - U.O.C. Cardiologia - Utic

    Sessa Aurunca, CE, 81037

  • Irccs Policlinico Multimedica - Uo Di Cardiologia

    Sesto San Giovanni, MI, 20099

  • Aou Senese Ospedale S. Maria Alle Scotte - Cardiologia

    Siena, SI, 53100

  • Casa Di Cura Villa Verde - Cardiologia

    Taranto, TA, 74100

  • Ospedale Ss. Annunziata - S.C. Cardiologia-Utic

    Taranto, TA, 74100

  • Ospedale San Giovanni Evangelista - U.O.C. Di Cardiologia - Utic

    Tivoli, RM, 00019

  • Aou Citta' Della Salute E Della Scienza - S.C. Cardiologia U

    Torino, To, 10126

  • Ospedale Mauriziano Umberto I - Sc Cardiologia

    Torino, TO, 10128

  • Ospedale Martini - Cardiologia (Mrt-Mv)

    Torino, TO, 10142

  • Ospedale Maria Vittoria - Cardiologia (Mrt-Mv)

    Torino, TO, 10149

  • Ospedale San Giovanni Bosco - Sc Cardiologia

    Torino, TO, 10154

  • Ospedale Santa Chiara - Divisione Di Cardiologia

    Trento, TN, 38122

  • Ospedali Treviglio-Caravaggio - Cardiologia

    Treviglio, BG, 24047

  • Ospedale Ca' Foncello - U.O.C. Cardiologia

    Treviso, TV, 31100

  • Azienda Osp. Cardinale G. Panico - U.O. Cardiologia - Utic

    Tricase, LE, 73039

  • Pou "Santa Maria Della Misericordia" - S.O.C. Cardiologia

    Udine, UD, 33100

  • Ospedale San Luca - U.O. Utic - Cardiologia

    Vallo della Lucania, SA, 84078

  • Ospedale Castelli - Soc Cardiologia Vco

    Verbania, VB, 28922

  • Ospedale Pietro E Michele Ferrero - Cardiologia E Utic

    Verduno, CN, 12060

  • Aoui Di Verona - U.O. Cardiologia

    Verona, VR, 37126

  • Ospedale Civile San Bortolo - U.O.C. Cardiologia

    Vicenza, VI, 36100

  • Nuovo Ospedale Di Vimercate - S.C. Cardiologia E Utic

    Vimercate, MB, 20871

  • Ospedale Belcolle - Uosd Utic Polo

    Viterbo, VT, 01100

  • Ospedale Civile - U.O. Di Cardiologia

    Voghera, PV, 27058

Other trials in Italy

About this study

This registry has the aim to assess the use of different antithrombotic therapies, including untested drug combinations, routinely used during the hospitalization phase, with their timing, route and dose of administration, in consecutive patients discharged with a diagnosis NSTEMI or STEMI in Italian Cardiac care Units (CCUs) during a four-week study period.

Read the detailed description

EYESHOT-2 is a prospective, multicenter, observational, nationwide survey of patients discharged with a diagnosis NSTEMI or STEMI admitted to Italian CCUs.

The survey will be designed to include all consecutive patients, who met the eligibility criteria, admitted in hospitals with or without cardiac catheterization laboratories and cardiac surgery facilities during a period of 4 weeks.

Medical subject headings
Acute Coronary Syndrome

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Antithrombotic therapies

    The primary objective of the study is to describe at a national level the different antithrombotic therapies (alone or in combination) commonly employed from admission to discharge in NSTEMI or STEMI patients undergoing different therapeutic strategies (PCI, CABG, conservative). A particular focus will be given to antithrombotic therapies (combinations, timing of administration, indications) used (a) before PCI (pre-treatment) (b) in the cath lab during PCI [use of Glycoprotein IIb/IIIa inhibitors (GPIs), cangrelor, anticoagulants] and (c) during hospital stay.

    Measured: 1 week

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted18 Mar 2024
  2. Study start1 Feb 2024
  3. Primary completion29 Feb 2024
  4. Study completion15 Mar 2024

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
2,806 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06316128
Sponsor's protocol ID
K26
Acronym
EYESHOT-2
Status last verified
Jun 2024
First submitted
5 Mar 2024
Last updated
2 Jan 2026
Results posted
No
FDA-regulated drug
No
FDA-regulated device
No

Publications

  • Zuin M, Lucci D, Calabro P, Nicosia A, Tizzani E, Mauro C, Temporelli PL, Gonzini L, Maggioni AP, Grimaldi M, Colivicchi F, Gabrielli D, Oliva F, De Luca L. Acute pharmacologic management of myocardial infarction in patients undergoing percutaneous coronary intervention: insights from the Italian nationwide EYESHOT-2 prospective registry. Eur Heart J Open. 2025 Nov 25;5(6):oeaf154. doi: 10.1093/ehjopen/oeaf154. eCollection 2025 Nov.

    PubMed 41377093

  • De Luca L, Maggioni AP, Cavallini C, Leonardi S, Lucci D, Sacco A, di Uccio FS, Valente S, Navazio A, Pascale V, Geraci G, Lanni F, Gulizia MM, Colivicchi F, Gabrielli D, Oliva F; EYESHOT-2 Investigators. Clinical profile and management of patients with acute myocardial infarction admitted to cardiac care units: The EYESHOT-2 registry. Int J Cardiol. 2025 Jan 1;418:132601. doi: 10.1016/j.ijcard.2024.132601. Epub 2024 Sep 28.

    PubMed 39349282

Questions about this trial

What is this clinical trial studying?

An observational study of Acute Coronary Syndrome, run by Heart Care Foundation at 189 sites in Italy.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 2 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 189 sites in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Antithrombotic therapies (time frame: 1 week). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06316128, which also lists 2 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jan 2026.

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