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Management of Acetabular FracturesFANADNCT06338228

A New Decisional Tree for the Management of Acetabular Fractures : Monocentric Observational Study

An observational study of Management of Acetabular Fractures, run by University Hospital, Grenoble at 1 site in France.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Acetabular fractures are challenging fractures to treat. Many fracture patterns occur, in a deep anatomical area surrounded by numerous vascular and nervous elements, generally in a polytraumatic context . Read more about this study

Who is it for?
Ages 18 to 100 years
Conditions the study is for
Management of Acetabular Fractures
How many people
250 participants
Where
1 siteFrance
Study dates
1 Mar 2024to 1 Mar 2025
How long will I take part?
1 Year
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 100 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: All patients managed between 01/01/2020 and 01/01/2023 for an acetabular fracture in our trauma center are included in this single-center retrospective study. The epidemiological data, the pre-operative management, the fracture patterns according to the Letournel and AO/OTA classification, the operative data and the radiological criteria (X-rays and CT scans) are retrospectively collected and analyzed.

Who may be able to join

  • Adult patient at the time of injury
  • Acetabular fracture
  • Pre-operative standard X-ray image
  • Pre-operative CT image
  • Post-operative X-ray standard image (AP-alar and obturator views)
  • Post-operative CT scan.
  • Willingness and ability to participate in the study

Who cannot join

  • Ipsilateral fracture femoral and/or associated pelvic ring fracture (Floating Hip C or B)
  • Pregnant, lactating women
  • Subject under administrative or judicial supervision

Trial locations and contacts

1 site in 1 country.

France1 site

  • Grenoble Alpes University Hospital,La tronche

    Grenoble, 38700

Other trials in France

About this study

Acetabular fractures are challenging fractures to treat. Many fracture patterns occur, in a deep anatomical area surrounded by numerous vascular and nervous elements, generally in a polytraumatic context . A reduction with less than 2 mm of incongruence is generally considered acceptable, limiting post-operative osteoarthritis that could rapidly require total hip arthroplasty. Due to the long learning curve, this surgery is limited to large reference centers

. In the last twenty years, the main series published in the literature are small series due to the rarity of the fractures and their trauma context (loss of follow-up, polytrauma patients…). The large variety of fracture patterns according to the Letournel classification creates a spread in patient distribution and decreases the power of statistical analysis. That is the reason why big series are rare and only a few of them allow significant conclusions . The other studies are meta-analyses with their limitations

Read more

The lack of consensus makes it difficult to interpret the results between series, so the investigators developed a decision tree to address this knowledge gap.

The aim of this study is to assess and compare the results of a decisional tree for acetabular fracture in a large cohort of patients from a well-known experimental trauma center.

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Study groups in NCT06338228
Study groupRoleWhat they receive
patients managed for Acetabular fracturecollect the data for all the patients managed and operated on between 01/01/2020 AND 31/01/2022 for Acetabular fracture

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. The main objective of the study is to evaluate and compare the results of a decision tree for the management of acetabulum fractures (also called acetabulum) in a large cohort of patients from the trauma center at Grenoble University Hospital

    Clinical results according to the Postel-Merle d'Aubigné score (PMA)

    Measured: 1 year

Secondary outcomes (8)

  1. Define the prognostic factors associated with poor clinical outcomes and total hip replacement surgery

    Prognostic factors from operative data

    Measured: 1 year

  2. Compare clinical and radiological findings with the literature

    Clinical outcomes according to Harris Hip Score(HHS)

    Measured: 1 year

  3. Compare clinical and radiological findings with the literature

    Clinical outcomes according to Oxford-12 HIP score (OXFORD HIP)

    Measured: 1 year

  4. Compare clinical and radiological findings with the literature

    Clinical outcomes according to MAJEED SCORES

    Measured: 1 year

  5. Compare clinical and radiological findings with the literature

    Clinical outcomes according to NUMERIC PAIN SCALE ( from 0-to10) 0 no pain 10 worst possible pain

    Measured: 1 year

  6. Compare clinical and radiological findings with the literature

    Clinical outcomes according to radiological scores

    Measured: 1 year

  7. Propose a new assessment of the traumatic hip joint based on PROMs (Patient Reported Outcomes Measures) via a dedicated digital application (Orthense by Digikare)

    Epidemiological data based on PROMs (Patient Reported Outcomes Measures) via a dedicated digital application (Orthense by Digikare)

    Measured: 1 year

  8. Evaluation of Outcomes and Complications of Early Weight Bearing in Older Adults

    Complications intra-operative and postoperative (including complications of early weight bearing)

    Measured: 1 year

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted29 Mar 2024
  2. Study start1 Mar 2024
  3. Primary completion1 Mar 2025
  4. Study completion1 Mar 2025

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Other
Enrolment
250 participants (actual)
Target duration
1 Year
IDs, dates and publications
ClinicalTrials.gov ID
NCT06338228
Sponsor's protocol ID
2023-A02458-37
Acronym
FANAD
Status last verified
Jan 2026
First submitted
14 Feb 2024
Last updated
8 Jan 2026
Results posted
No
FDA-regulated drug
No
FDA-regulated device
No

Publications

  • JUDET R, JUDET J, LETOURNEL E. FRACTURES OF THE ACETABULUM: CLASSIFICATION AND SURGICAL APPROACHES FOR OPEN REDUCTION. PRELIMINARY REPORT. J Bone Joint Surg Am. 1964 Dec;46:1615-46. No abstract available.

    PubMed 14239854

  • Matta JM, Anderson LM, Epstein HC, Hendricks P. Fractures of the acetabulum. A retrospective analysis. Clin Orthop Relat Res. 1986 Apr;(205):230-40.

    PubMed 3698382

  • Matta JM, Merritt PO. Displaced acetabular fractures. Clin Orthop Relat Res. 1988 May;(230):83-97.

    PubMed 3365902

  • Letournel E. Acetabulum fractures: classification and management. Clin Orthop Relat Res. 1980 Sep;(151):81-106.

    PubMed 7418327

  • Negrin LL, Seligson D. Results of 167 consecutive cases of acetabular fractures using the Kocher-Langenbeck approach: a case series. J Orthop Surg Res. 2017 Apr 26;12(1):66. doi: 10.1186/s13018-017-0563-6.

    PubMed 28446184

  • Kreder HJ, Rozen N, Borkhoff CM, Laflamme YG, McKee MD, Schemitsch EH, Stephen DJ. Determinants of functional outcome after simple and complex acetabular fractures involving the posterior wall. J Bone Joint Surg Br. 2006 Jun;88(6):776-82. doi: 10.1302/0301-620X.88B6.17342.

    PubMed 16720773

  • Wang XJ, Lu Li, Zhang ZH, Su YX, Guo XS, Wei XC, Wei L. Ilioinguinal approach versus Stoppa approach for open reduction and internal fixation in the treatment of displaced acetabular fractures: A systematic review and meta-analysis. Chin J Traumatol. 2017 Aug;20(4):229-234. doi: 10.1016/j.cjtee.2017.01.005. Epub 2017 Jun 19.

    PubMed 28709737

  • Shazar N, Eshed I, Ackshota N, Hershkovich O, Khazanov A, Herman A. Comparison of acetabular fracture reduction quality by the ilioinguinal or the anterior intrapelvic (modified Rives-Stoppa) surgical approaches. J Orthop Trauma. 2014 Jun;28(6):313-9. doi: 10.1097/01.bot.0000435627.56658.53.

    PubMed 24100918

  • Giannoudis PV, Grotz MR, Papakostidis C, Dinopoulos H. Operative treatment of displaced fractures of the acetabulum. A meta-analysis. J Bone Joint Surg Br. 2005 Jan;87(1):2-9.

    PubMed 15686228

  • Mears DC, Velyvis JH, Chang CP. Displaced acetabular fractures managed operatively: indicators of outcome. Clin Orthop Relat Res. 2003 Feb;(407):173-86. doi: 10.1097/00003086-200302000-00026.

    PubMed 12567145

  • Murphy D, Kaliszer M, Rice J, McElwain JP. Outcome after acetabular fracture. Prognostic factors and their inter-relationships. Injury. 2003 Jul;34(7):512-7. doi: 10.1016/s0020-1383(02)00349-2.

    PubMed 12832177

  • Tannast M, Najibi S, Matta JM. Two to twenty-year survivorship of the hip in 810 patients with operatively treated acetabular fractures. J Bone Joint Surg Am. 2012 Sep 5;94(17):1559-67. doi: 10.2106/JBJS.K.00444.

    PubMed 22992846

  • Boudissa M, Ruatti S, Kerschbaumer G, Milaire M, Merloz P, Tonetti J. Part 2: outcome of acetabular fractures and associated prognostic factors-a ten-year retrospective study of one hundred and fifty six operated cases with open reduction and internal fixation. Int Orthop. 2016 Oct;40(10):2151-2156. doi: 10.1007/s00264-015-3070-6. Epub 2015 Dec 21.

    PubMed 26686672

  • Boudissa M, Francony F, Kerschbaumer G, Ruatti S, Milaire M, Merloz P, Tonetti J. Epidemiology and treatment of acetabular fractures in a level-1 trauma centre: Retrospective study of 414 patients over 10 years. Orthop Traumatol Surg Res. 2017 May;103(3):335-339. doi: 10.1016/j.otsr.2017.01.004. Epub 2017 Feb 22.

    PubMed 28235575

Questions about this trial

What is this clinical trial studying?

An observational study of Management of Acetabular Fractures, run by University Hospital, Grenoble at 1 site in France.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 7 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 8 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

The main objective of the study is to evaluate and compare the results of a decision tree for the management of acetabulum fractures (also called acetabulum) in a large cohort of patients from the trauma center at Grenoble University Hospital (time frame: 1 year). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06338228, which also lists 14 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jan 2026.

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