Cardiac SurgeryNCT06340464
Preoperative Nutritional Status Scores to Predict PPC in Elderly With Cardiac Surgery
An observational study of Cardiac Surgery and Elderly Patient, run by Prince of Songkla University at 1 site in Thailand.
Trial summary
This prospective study investigates prognostic values and compares the role of nutritional status by using GNRI, MNA-SF, PNI, and NAF in predicting post-operative pulmonary complication among elderly patients with cardiac surgery. Read more about this study
- Who is it for?
- Ages 60 years and older
- Conditions the study is for
- Cardiac Surgery, Elderly Patient, Postoperative Pulmonary Complication
- What is being tested?
- Nutrition scoring systems
- How many people
- 217 participants
- Where
- 1 siteThailand
- Study dates
- 1 Jun 2024to 30 Apr 2026
- How long will I take part?
- 1 Month
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Elderly patients (aged ≥ 60 years old) who undergoing cardiac surgery in Songklanagarind hospital, Songkla, Thailand
Who may be able to join
- Elderly patient age ≥ 60 years
- Open heart surgical procedure on pump (CABG, valvular disease, combine CABG and valve surgery
- Elective surgery
Who cannot join
- Emergency surgery
Trial locations and contacts
1 site in 1 country.
Thailand1 site
Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University
Hat Yai, Changwat Songkhla, 90110
About this study
Official title: Investigation & Comparison of the Effects of Preoperative Nutritional Status Scores to Predict Post-op Pulmonary Complications Among Elderly Patients With Cardiac Surgery
This prospective study investigates prognostic values and compares the role of nutritional status by using GNRI, MNA-SF, PNI, and NAF in predicting post-operative pulmonary complication among elderly patients with cardiac surgery.
Read the detailed description
In this prospective cohort study, 217 patients aged ≥60 years undergoing elective cardiac surgery at a tertiary university hospital were enrolled. Preoperative nutritional status was assessed using GNRI, MNA-SF, PNI, and NAF. The primary outcome was PPC occurrence during hospitalization. Predictive performance was evaluated using receiver operating characteristic (ROC) analysis, and multivariable logistic regression identified independent predictors
- Conditions
- Cardiac Surgery, Elderly Patient, Postoperative Pulmonary Complication, Nutrition Scoring System
- Being tested
- Nutrition scoring systems
- Keywords
- Cardiac surgery, Elderly, Aged, Postoperative pulmonary complication, Nutrition scoring system, GNRI, MNA, PNI
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nutrition scoring systemsOther
GNRI, MNA-SF, PNI, and NAF
| Study group | Role | What they receive |
|---|---|---|
| older patients | patients aged ≥60 years undergoing elective cardiac surgery Receives: Other: Nutrition scoring systems |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative pulmonary complication
PPCs such as pneumonia, pulmonary embolism, ventilation longer than 24 h, pleural effusions necessitating drainage and reintubation within 72 h of extubation
Measured: 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Apr 2024
- Study start1 Jun 2024
- Primary completion30 Apr 2026
- Study completion30 Apr 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cardiac SurgeryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 217 participants (actual)
- Target duration
- 1 Month
Sponsor and investigators
- Lead sponsor
- Prince of Songkla University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Panalee Kittisopaporn, Prince of Songkla University
- Investigators
- Panalee Kittisopaporn, Principal investigator, Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06340464
- Sponsor's protocol ID
- REC.67-018-8-1
- Status last verified
- Mar 2024
- First submitted
- 25 Mar 2024
- Last updated
- 16 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: ethical considerations
Study at a glance
From the registry record, last updated by the sponsor on 16 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation & Comparison of the Effects of Preoperative Nutritional Status Scores to Predict Post-op Pulmonary Complications Among Elderly Patients With Cardiac Surgery
- ClinicalTrials.gov ID
- NCT06340464
- Acronym / sponsor ID
- REC.67-018-8-1
- Conditions
- Cardiac Surgery, Elderly Patient, Postoperative Pulmonary Complication, Nutrition Scoring System
- Keywords
- Cardiac surgery, Elderly, Aged, Postoperative pulmonary complication, Nutrition scoring system, GNRI, MNA, PNI
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 217 participants (actual)
- Lead sponsor
- Prince of Songkla UniversityUniversity, hospital or other
- Study start
- 1 Jun 2024 (actual)
- Primary completion
- 30 Apr 2026 (actual)
- Study completion
- 30 Apr 2026 (actual)
- First posted
- 1 Apr 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective study investigates prognostic values and compares the role of nutritional status by using GNRI, MNA-SF, PNI, and NAF in predicting post-operative pulmonary complication among elderly patients with cardiac surgery.
Detailed description
In this prospective cohort study, 217 patients aged ≥60 years undergoing elective cardiac surgery at a tertiary university hospital were enrolled. Preoperative nutritional status was assessed using GNRI, MNA-SF, PNI, and NAF. The primary outcome was PPC occurrence during hospitalization. Predictive performance was evaluated using receiver operating characteristic (ROC) analysis, and multivariable logistic regression identified independent predictors
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 1 Month
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| older patients | – | Other: Nutrition scoring systemspatients aged ≥60 years undergoing elective cardiac surgery |
Who may qualify
- Ages
- 60 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Elderly patients (aged ≥ 60 years old) who undergoing cardiac surgery in Songklanagarind hospital, Songkla, Thailand
Key inclusion criteria (3 listed)
- Elderly patient age ≥ 60 years
- Open heart surgical procedure on pump (CABG, valvular disease, combine CABG and valve surgery
- Elective surgery
Key exclusion criteria (1 listed)
- Emergency surgery
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nutrition scoring systemsGNRI, MNA-SF, PNI, and NAF | Other | older patients |
Primary outcome
Postoperative pulmonary complication
Time frame: 1 month
PPCs such as pneumonia, pulmonary embolism, ventilation longer than 24 h, pleural effusions necessitating drainage and reintubation within 72 h of extubation
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jun 2026.
- Individual participant dataSharing planned: No. ethical considerations
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Panalee Kittisopaporn principal investigator
Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cardiac Surgery and Elderly Patient, run by Prince of Songkla University at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative pulmonary complication (time frame: 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jun 2026.