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Cannabis UseNCT06358144

Cannabis Edibles Packaging Imagery Experiment

A study testing Packaging imagery in people with Cannabis Use, run by Wake Forest University Health Sciences at 1 site in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The purpose of this study is to assess differences in perceptions of product appeal, harm, and subsequent willingness to try cannabis edibles products with/without packaging imagery. Read more about this study

Who is it for?
Ages 18 to 65 yearsHealthy volunteers can take part
Conditions the study is for
Cannabis Use
What is being tested?
Packaging imagery
Could I receive a placebo?
No, everyone receives an active treatment
How many people
1,260 participants
Where
1 siteUnited States
Study dates
23 May 2024to 19 Jun 2024
Phase
Interventional
Are there results?
Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 65 years
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Who may be able to join

  • US resident
  • Aged 18-65, inclusive
  • Up to 13% of participants will be those who identify as Black/African American
  • Up to 16% of participants will be those who identify as Hispanic
  • Approximately 50% of participants will be past year cannabis users
  • Was not a participant on the anteceding experiment, Cannabis Edibles Packaging Descriptors Experiment

Who cannot join

  • Does not currently reside in the United States
  • Younger than 18 or older than 65
  • Does not provide information regarding history of cannabis use
  • Otherwise eligible but demographic and/or user group quotas have been met
  • Was a participant on the anteceding experiment, Cannabis Edibles Packaging Descriptors Experiment

Trial locations and contacts

1 site in 1 country.

United States1 site

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157

Other trials in United States

About this study

Official title: The Impact of Cannabis Edibles Packaging Descriptors on Consumer Appeal, Harm Perceptions and Willingness to Try: Packaging Imagery Experiment

The purpose of this study is to assess differences in perceptions of product appeal, harm, and subsequent willingness to try cannabis edibles products with/without packaging imagery.

Read the detailed description

Cannabis edibles are rapidly leading the legal recreational cannabis market. Cannabis edibles present health harms that are not typical of smoked marijuana, including accidental overconsumption of high levels of Tetrahydrocannabinol (THC) . Product packaging plays an important role in influencing perceptions of a product's appeal and potential harm. This experiment will assign participants to view real cannabis edibles packaging edited with one of four images commonly found on real cannabis edibles products, and ask a series of questions to assess perceptions of product appeal and harm. One group of participants will serve as the control and will see the same cannabis edibles packaging without any imagery.

Conditions
Cannabis Use
Being tested
Packaging imagery, No Imagery (Control)
Keywords
Tetrahydrocannabinol (THC), cannabis edibles, Product packaging

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Packaging imageryBehavioural

    Also called four cannabis edibles packages

    Participants in the four intervention conditions will be shown four cannabis edibles packages that have been altered to contain one of the imagery themes. All participants will see the same four products, and each condition will see the products with the same imagery theme.

  • No Imagery (Control)Behavioural

    Also called No Imagery

    Participants in the control condition will see the same four product packages, but without any added imagery.

Study groups in NCT06358144
Study groupRoleWhat they receive
Flavor ImageryExperimentalFour edible product packages (gummies, chocolate, mints, cookies) with package imagery in a flavor theme.
Receives: Behavioral: Packaging imagery
Animal ImageryExperimentalFour edible product packages (gummies, chocolate, mints, cookies) with package imagery in an animal theme.
Receives: Behavioral: Packaging imagery
Nature ImageryExperimentalFour edible product packages (gummies, chocolate, mints, cookies) with package imagery in a nature theme.
Receives: Behavioral: Packaging imagery
Medical ImageryExperimentalFour edible product packages (gummies, chocolate, mints, cookies) with package imagery in a medical theme.
Receives: Behavioral: Packaging imagery
No Imagery (Control)ExperimentalFour edible product packages (gummies, chocolate, mints, cookies) without any added packaging imagery.
Receives: Behavioral: No Imagery (Control)

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Product Appeal Scoring

    One item to assess the appeal of the product. Results will be reported as mean for all products within condition.

    Question: How appealing is this product to you? Response options: (0) Not at all appealing to (10) Very appealing

    Measured: After exposure to product packaging - up to 1 min

  2. Package Appeal Scoring

    One item to assess appeal of the packaging of the product. Results will be reported as mean for all products within condition.

    Question: How appealing is this packaging to you? Response options: (0) Not at all appealing to (10) Very appealing

    Measured: After exposure to product packaging - up to 1 min

  3. Product Harm Perceptions (Absolute) Scoring

    After exposure to product packaging; 1 min One item to assess participants' opinions of safety of the product. Results will be reported as the number of each type of response.

    Question: How safe do you think it would be to eat the edible in this package? Response options: (1) Completely unsafe, (2) Somewhat unsafe, (3) Somewhat safe, (4) Completely safe

    Measured: After exposure to product packaging - up to 1 min

  4. Package Harm Perceptions (Absolute) Scoring

    One item to assess participants' opinions of product safety based on the packaging. Results will be reported as the number of each type of response.

    Question: How much does this packaging make you think this edible is safe to consume? Response options: (1) Not at all; (2) A little; (3) Somewhat; (4) A lot

    Measured: After exposure to product packaging - up to 1 min

  5. Willingness to Try Free Sample Scoring

    One question will assess the participant's willingness to try the product shown. Results will be reported as the number of each type of response.

    Question: How interested would you be in a free sample of this product? Response options: (1) Not at all; (2) Slightly; (3) Somewhat; (4) Moderately; (5) Very

    Measured: After exposure to product packaging - up to 1 min

  6. Willingness to Try Product Scoring

    One item to assess the participants' willingness to try the product based on the packaging. Results will be reported as the number of each type of response.

    Question: How much does seeing this packaging make you want to try this edible? Response options: (1) Not at all; (2) A little; (3) Somewhat; (4) A lot

    Measured: After exposure to product packaging - up to 1 min

Secondary outcomes (2)

  1. Appeal to Children Scoring

    One item to assess the participants' assessment of the product packaging's potential appeal to children. Results will be reported as mean for all products within condition.

    Question: How appealing do you think this packaging would be to children? Response options: (0) Not at all appealing to (10) Very appealing

    Measured: After exposure to product packaging - up to 1 min

  2. Harm Perceptions (Relative) Scoring

    One question assessing participants' opinions of safety of the product compared to other, similar, products. Results will be reported as the number of each type of response.

    Question: Compared to other edible products on the market, how safe do you think the edible in this package is? Response options: (1) Much less safe; (2) Somewhat less safe; (3) As safe; (4) Somewhat safer; (5) Much safer

    Measured: After exposure to product packaging - up to 1 min

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted10 Apr 2024
  2. Study start23 May 2024
  3. Primary completion19 Jun 2024
  4. Study completion19 Jun 2024

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Prevention
Allocation
Randomised
Intervention model
Parallel groups
Model description
Participants will complete a 15-minute online survey, where they will be randomized to one of five conditions: four intervention conditions with a different image on the package and one without any imagery.
Masking
Single blind
Who is masked
Participant
Enrolment
1,260 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06358144
Sponsor's protocol ID
IRB00111438
Other IDs
R01DA053209
Status last verified
Mar 2025
First submitted
5 Apr 2024
Last updated
8 Jun 2025
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Reboussin BA, Lazard AJ, Wagoner KG, Sutfin EL, Romero-Sandoval EA, Egan KL, Suerken CK, Zizzi AR, Horton OE, Lake S, Varma T, Cork K, Cornacchione Ross J. The Impact of Product Packaging on Perceptions of Cannabis Edibles: Results from Two Randomized Experiments. Subst Use Misuse. 2026 May 23:1-11. doi: 10.1080/10826084.2026.2670605. Online ahead of print.

    PubMed 42176349

Questions about this trial

What is this clinical trial studying?

A study testing Packaging imagery in people with Cannabis Use, run by Wake Forest University Health Sciences at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 8 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 8 Jun 2025). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Product Appeal Scoring (time frame: After exposure to product packaging - up to 1 min). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06358144, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jun 2025.

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