Emergency MedicineeCREAM-UC2NCT06372379
Development of a Multipurpose Dashboard to Monitor the Situation of Emergency Departments
An observational study of Emergency Medicine, run by Mario Negri Institute for Pharmacological Research at 2 sites in Italy.
Trial summary
An emergency department (ED) is a healthcare service that provides the first clinical assessment and treatment to patients with various acute conditions. These departments, however, are often overwhelmed by the large volume of patients. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Emergency Medicine
- How many people
- 162,000 participants
- Where
- 2 sitesItaly
- Study dates
- 22 Sep 2025to Feb 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Adult, Older adult
Study population: All adult patients who arrived at participating emergency departments between January 1, 2025 and December 31, 2025
Who may be able to join
- Adult
- Arrived at emergency department between 1 January 2025 and 31 December 2025
Who cannot join
- None
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Italy2 sites, 2 recruiting
- Recruiting
Ospedale San Giovanni Bosco
Torino
Franco Aprà, +39 0112402349, franco.apra@aslcittaditorino.it
- Recruiting
Ospedale Sant'Andrea
Vercelli
Sergio Tartaglia, +39 0161 593111, srtartaglia@gmail.com
About this study
Official title: Development of a Multipurpose Dashboard to Monitor the Situation of Emergency Departments. An Observational Prospective Study
An emergency department (ED) is a healthcare service that provides the first clinical assessment and treatment to patients with various acute conditions. These departments, however, are often overwhelmed by the large volume of patients. As a consequence, ED crowding has become a global concern and has been correlated to reduced timeliness and effectiveness of care and increased patient mortality. Concerning input, 20% to 30% of patients are brought to the ED by ambulance; the remaining are self-presenting for the vast majority. Notably, non-urgent conditions characterize a high proportion of all ED visits worldwide, and almost all of these visits involve self-presenting patients. Increasing the awareness of these patients about the mandate of EDs and the real-time situation of the neighboring emergency departments has the potential to reduce the self-presentation of patients with minor, non-urgent conditions. Such patient empowerment can be achieved through a dashboard. Concerning throughput, working in the ED requires emergency physicians and nurses to treat many patients at once while maintaining situational awareness of the surroundings. This is especially true for the head of the department, but it also holds for all physicians. It can be crucial, for example, for physicians to know if there is a bottleneck in the flow of the entire patient care process, such as a particularly high average waiting time for radiology reporting or cardiologic consultation. The availability of this information allows countermeasures to be put in place to regain efficiency. All this can be achieved through dedicated dashboards automatically fed from various information system. In addition, appropriate dashboards also enable health policymakers to monitor specific epidemiological phenomena, such as the emergence of certain infectious diseases, in a timely manner.
- Conditions
- Emergency Medicine
- Being tested
- no intervention
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
no interventionOther
no intervention
| Study group | Role | What they receive |
|---|---|---|
| Adults who attended the emergency department | Not described Receives: Other: no intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Daschboards
Develop three different control panels for three different end-users, specifically:
- Dashboard for citizens
- Dashboard for healthcare providers
- Dashboard for healthcare policymakers The aim is to extract the needed information from heterogeneous sources and to feed the dashboards according to the needs of the end-users. On the whole, for citizens, the dashboard will be designed to empower them to choose the most appropriate ED to attend or to consider a different, more relevant or more efficient, health service; for healthcare providers, the dashboard will provide a clear and immediate picture of the ED situation in terms of patient flow and workflow; for healthcare policymakers, the dashboard will provide the ability to monitor specific phenomena of interest, such as ED crowding level, possible incidence of pre-specified epidemiological phenomena, availability and timeliness of primary and secondary patient transfers, ambulance offload delays, etc.
Measured: September 2024 - September 2027
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Apr 2024
- Study start22 Sep 2025
- Primary completionJan 2027 (estimated)
- Study completionFeb 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Emergency MedicineStudies of the same condition, open and under way.
- More trials run by Mario Negri Institute for Pharmacological ResearchThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 162,000 participants (estimated)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Collaborators
- Astir s.r.l., Orobix Life S.r.l., Fondazione Bruno Kessler
- Responsible party
- Sponsor
- Investigators
- Guido Bertolini, MD, Principal investigator, Istituto Di Ricerche Farmacologiche Mario Negri
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06372379
- Sponsor's protocol ID
- 8780_UC2
- Acronym
- eCREAM-UC2
- Status last verified
- May 2026
- First submitted
- 9 Apr 2024
- Last updated
- 9 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The anonymized data derived from this study could be shared for secondary use in the context of research projects.
Study at a glance
From the registry record, last updated by the sponsor on 9 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Development of a Multipurpose Dashboard to Monitor the Situation of Emergency Departments. An Observational Prospective Study
- ClinicalTrials.gov ID
- NCT06372379
- Acronym / sponsor ID
- eCREAM-UC2 / 8780_UC2
- Conditions
- Emergency Medicine
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 162,000 participants (estimated)
- Lead sponsor
- Mario Negri Institute for Pharmacological ResearchUniversity, hospital or other
- Collaborators
- Astir s.r.l., Orobix Life S.r.l., Fondazione Bruno Kessler
- Study start
- 22 Sep 2025 (actual)
- Primary completion
- Jan 2027 (estimated)
- Study completion
- Feb 2027 (estimated)
- First posted
- 18 Apr 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
An emergency department (ED) is a healthcare service that provides the first clinical assessment and treatment to patients with various acute conditions. These departments, however, are often overwhelmed by the large volume of patients. As a consequence, ED crowding has become a global concern and has been correlated to reduced timeliness and effectiveness of care and increased patient mortality. Concerning input, 20% to 30% of patients are brought to the ED by ambulance; the remaining are self-presenting for the vast majority. Notably, non-urgent conditions characterize a high proportion of all ED visits worldwide, and almost all of these visits involve self-presenting patients. Increasing the awareness of these patients about the mandate of EDs and the real-time situation of the neighboring emergency departments has the potential to reduce the self-presentation of patients with minor, non-urgent conditions. Such patient empowerment can be achieved through a dashboard. Concerning throughput, working in the ED requires emergency physicians and nurses to treat many patients at once while maintaining situational awareness of the surroundings. This is especially true for the head of the department, but it also holds for all physicians. It can be crucial, for example, for physicians to know if there is a bottleneck in the flow of the entire patient care process, such as a particularly high average waiting time for radiology reporting or cardiologic consultation. The availability of this information allows countermeasures to be put in place to regain efficiency. All this can be achieved through dedicated dashboards automatically fed from various information system. In addition, appropriate dashboards also enable health policymakers to monitor specific epidemiological phenomena, such as the emergence of certain infectious diseases, in a timely manner.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Adults who attended the emergency department | – | Other: no intervention |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- All adult patients who arrived at participating emergency departments between January 1, 2025 and December 31, 2025
Key inclusion criteria (2 listed)
- Adult
- Arrived at emergency department between 1 January 2025 and 31 December 2025
Key exclusion criteria (1 listed)
- None
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| no interventionno intervention | Other | Adults who attended the emergency department |
Primary outcome
Daschboards
Time frame: September 2024 - September 2027
Develop three different control panels for three different end-users, specifically: 1. Dashboard for citizens 2. Dashboard for healthcare providers 3. Dashboard for healthcare policymakers The aim is to extract the needed information from heterogeneous sources and to feed the dashboards according to the needs of the end-users. On the whole, for citizens, the dashboard will be designed to empower them to choose the most appropriate ED to attend or to consider a different, more relevant or more efficient, health service; for healthcare providers, the dashboard will provide a clear and immediate picture of the ED situation in terms of patient flow and workflow; for healthcare policymakers, the dashboard will provide the ability to monitor specific phenomena of interest, such as ED crowding level, possible incidence of pre-specified epidemiological phenomena, availability and timeliness of primary and secondary patient transfers, ambulance offload delays, etc.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Oct 2026.
- Individual participant dataSharing planned: Yes. The anonymized data derived from this study could be shared for secondary use in the context of research projects.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Guido Bertolini, MD principal investigator
Istituto Di Ricerche Farmacologiche Mario Negri
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Emergency Medicine, run by Mario Negri Institute for Pharmacological Research at 2 sites in Italy.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 9 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Chiara Pandolfini (0039 02 39014 253, chiara.pandolfini@marionegri.it), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Daschboards (time frame: September 2024 - September 2027). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Oct 2026.