Mental HealthMBINCT06392100
MBI in Generation Z Nursing Students During Clinical Practicum
A study testing Mindfulness-Based Intervention in people with Mental Health and Anxiety, run by National Taipei University of Nursing and Health Sciences at 1 site in Taiwan.
Trial summary
This study is a randomized clinical trial design. The research subjects were the internship nursing students in the nursing department of a nursing school in the northern Taiwan. Read more about this study
- Who is it for?
- Ages 18 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Mental Health, Anxiety, Depression
- What is being tested?
- Mindfulness-Based Intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 39 participants
- Where
- 1 siteTaiwan
- Study dates
- 1 Sep 2024to 8 Sep 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- (1) Nursing students during clinical practicum (2) Clear consciousness.
Who cannot join
- -(1) Students diagnosed with schizophrenia, anxiety, depression or affective psychosis.
- (2)Taking anti-anxiety medicine treatment or anti-depressant medicine treatment.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effectiveness of a Mindfulness-Based Intervention in Mental Health, Anxiety, Depression, Stress and Resilience in Generation Z Nursing Students During Clinical Practicum
This study is a randomized clinical trial design. The research subjects were the internship nursing students in the nursing department of a nursing school in the northern Taiwan.
The experimental group received mindfulness-based stress reduction intervention, while the control group received routine care with weekly line care messages from class instructors. Both groups took the post-test before the internship (T0), during the internship (T1), after the internship (T2), and one month after the internship (T3), a total of 4 times. The contents include psychological well-being scale; anxiety, depression, stress scale and mental scale.
Read the detailed description
Students need to learn a lot of new medical knowledge and skills during clinical internships, which requires time and effort. However, this kind of learning pressure may put a considerable burden on nursing students, especially anxiety, depression, and stress. Through effective coping strategies, students can improve their confidence in facing clinical situations.
Mindfulness-based stress reduction is a stress-reduction method based on mindfulness meditation. It can relieve the physical and mental stress and anxiety of high-stress people, improve sleep quality, chronic fatigue, and enhance concentration.
The purpose of this study is to explore the effectiveness of mindfulness-based stress reduction intervention on anxiety, depression, and stress in clinical practice of nursing students.
This study adopted a randomized clinical experimental research design. Nursing students from a fifth-level college in the north were selected as the research subjects. A total of 80 people were recruited. Nursing intern students who were willing to participate in the study were randomly assigned and divided into an experimental group of 40 people and a control group. 40 people, the experimental group participated in the mindfulness-based stress reduction course for 8 weeks. The mindfulness-based stress reduction course was led by a certified mindfulness-based stress reduction teacher, once a week, 2 hours each time, for 8 consecutive weeks; the students in the control group received weekly line care messages from the class instructor. Research tools include the General Health Status Scale, Anxiety and Depression Stress Scale, and Mental Resilience Scale. The data were analyzed using SPSS20.0 for Windows.
- Conditions
- Mental Health, Anxiety, Depression, Resilience
- Being tested
- Mindfulness-Based Intervention
- Keywords
- Mindfulness-Based Stress Reduction, Generation Z Nursing Students
- Medical subject headings
- Psychological Well-Being, Anxiety Disorders, Depression
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mindfulness-Based InterventionBehavioural
Also called line care messages
Mindfulness-based stress reduction interventions include: breathing awareness, loving-kindness meditation, body scan, walking meditation, sitting body awareness, eating meditation, and deep breathing exercises.
| Study group | Role | What they receive |
|---|---|---|
| Mindfulness-Based Intervention in Generation Z Nursing Students During Clinical Practicum | Experimental | The experimental group received mindfulness-based stress reduction intervention for 8 weeks. Receives: Behavioral: Mindfulness-Based Intervention |
| line care messages in Generation Z Nursing Students During Clinical Practicum | No intervention | The control group received line care messages weekly from instructors during clinical practicum. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mental Health
Psychological Well-Being Scale (PWBS-18) : Ryff \& Keyes (1995) proposed that happiness is not only a happy psychological experience, but also a perfect and true performance through one's own efforts. The original scale has 6 facets and 25 questions.
Measured: Pre-intervention(T0)、Two week after clinical practium begins (T1)、Four week after clinical practium begins(T2)、Two months after clinical practium(T3)
Anxiety, Depression, Stress
Depression, Anxiety and Stress Scale - 21 Items (DASS-21)：Developed by scholars at the University of New South Wales in Australia in 1995, it is an internationally authoritative psychological stress assessment tool. It uses a short version of 21 questions to assess common depressive emotions such as depression, anxiety, and stress. There are 21 questions in total, which combine subjective The degree of various induced emotional states is used as an evaluation index, using a 4-point scale, where 1 means not consistent, 2 means sometimes consistent, 3 means usually consistent, and 4 means always consistent.
Measured: Pre-intervention(T0)、Two week after clinical practium begins (T1)、Four week after clinical practium begins(T2)、Two months after clinical practium(T3)
Secondary outcomes (1)
Resilience
Resilience Scale (RS)：The Resilience Scale of Wagnild and Young (1993) focuses on measuring the resilience of individuals at the psychological level, using a seven-point Likert scale with a total of 25 questions.
Measured: Pre-intervention(T0)、Two week after clinical practium begins (T1)、Four week after clinical practium begins(T2)、Two months after clinical practium(T3)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Apr 2024
- Study start1 Sep 2024
- Primary completion12 May 2025
- Study completion8 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Mental HealthStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- The experimental group received mindfulness-based stress reduction intervention, while the control group received weekly line care messages from class instructors. Both groups took the post-test before the internship (T0), during the internship (T1), after the internship (T2), and one month after the internship (T3), a total of 4 times. The contents include psychological well-being scale; anxiety, depression, stress scale and mental toughness scale.
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 39 participants (actual)
Sponsor and investigators
- Lead sponsor
- National Taipei University of Nursing and Health Sciences
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Chien Chih-Yin, National Taipei University of Nursing and Health Sciences
- Investigators
- Chih-yin Chien, master, Study chair, MacKay Junior College of Medicine, Nursing, and Management
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06392100
- Sponsor's protocol ID
- MKC-24MMHIS148e
- Acronym
- MBI
- Status last verified
- Apr 2026
- First submitted
- 23 Apr 2024
- Last updated
- 13 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: This study is unwilling to share research data because of confidentiality, privacy protection, legal restrictions, or terms of funding. Additionally, the inability to handle shared data requires additional time and resources to process and manage
Publications
Dong C, Xia L, Zhao C, Zhang X, He J, Zhang G, Zhang J. Prospective association between perceived stress and anxiety among nursing college students: the moderating roles of career adaptability and professional commitment. BMC Psychiatry. 2023 Jun 1;23(1):388. doi: 10.1186/s12888-023-04887-6.
PubMed 37264378Gurdil Yilmaz S, Yildiz Karadeniz E, dem Lafci D. Clinical-practice stress levels and factors affecting these on first-year nursing students. Perspect Psychiatr Care. 2022 Oct;58(4):3009-3015. doi: 10.1111/ppc.13070. Epub 2022 Mar 22.
PubMed 35318676O'Driscoll M, Byrne S, Mc Gillicuddy A, Lambert S, Sahm LJ. The effects of mindfulness-based interventions for health and social care undergraduate students - a systematic review of the literature. Psychol Health Med. 2017 Aug;22(7):851-865. doi: 10.1080/13548506.2017.1280178. Epub 2017 Jan 19.
PubMed 28103700Uysal N, Caliskan BB. The effects of mindfulness-based stress reduction on mindfulness and stress levels of nursing students during first clinical experience. Perspect Psychiatr Care. 2022 Oct;58(4):2639-2645. doi: 10.1111/ppc.13104. Epub 2022 Apr 30.
PubMed 35488858
Study at a glance
From the registry record, last updated by the sponsor on 13 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of a Mindfulness-Based Intervention in Mental Health, Anxiety, Depression, Stress and Resilience in Generation Z Nursing Students During Clinical Practicum
- ClinicalTrials.gov ID
- NCT06392100
- Acronym / sponsor ID
- MBI / MKC-24MMHIS148e
- Conditions
- Mental Health, Anxiety, Depression, Resilience
- Keywords
- Mindfulness-Based Stress Reduction, Generation Z Nursing Students
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 39 participants (actual)
- Lead sponsor
- National Taipei University of Nursing and Health SciencesUniversity, hospital or other
- Study start
- 1 Sep 2024 (actual)
- Primary completion
- 12 May 2025 (actual)
- Study completion
- 8 Sep 2025 (actual)
- First posted
- 30 Apr 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is a randomized clinical trial design. The research subjects were the internship nursing students in the nursing department of a nursing school in the northern Taiwan.
The experimental group received mindfulness-based stress reduction intervention, while the control group received routine care with weekly line care messages from class instructors. Both groups took the post-test before the internship (T0), during the internship (T1), after the internship (T2), and one month after the internship (T3), a total of 4 times. The contents include psychological well-being scale; anxiety, depression, stress scale and mental scale.
Detailed description
Students need to learn a lot of new medical knowledge and skills during clinical internships, which requires time and effort. However, this kind of learning pressure may put a considerable burden on nursing students, especially anxiety, depression, and stress. Through effective coping strategies, students can improve their confidence in facing clinical situations.
Mindfulness-based stress reduction is a stress-reduction method based on mindfulness meditation. It can relieve the physical and mental stress and anxiety of high-stress people, improve sleep quality, chronic fatigue, and enhance concentration.
The purpose of this study is to explore the effectiveness of mindfulness-based stress reduction intervention on anxiety, depression, and stress in clinical practice of nursing students.
This study adopted a randomized clinical experimental research design. Nursing students from a fifth-level college in the north were selected as the research subjects. A total of 80 people were recruited. Nursing intern students who were willing to participate in the study were randomly assigned and divided into an experimental group of 40 people and a control group. 40 people, the experimental group participated in the mindfulness-based stress reduction course for 8 weeks. The mindfulness-based stress reduction course was led by a certified mindfulness-based stress reduction teacher, once a week, 2 hours each time, for 8 consecutive weeks; the students in the control group received weekly line care messages from the class instructor. Research tools include the General Health Status Scale, Anxiety and Depression Stress Scale, and Mental Resilience Scale. The data were analyzed using SPSS20.0 for Windows.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- The experimental group received mindfulness-based stress reduction intervention, while the control group received weekly line care messages from class instructors. Both groups took the post-test before the internship (T0), during the internship (T1), after the internship (T2), and one month after the internship (T3), a total of 4 times. The contents include psychological well-being scale; anxiety, depression, stress scale and mental toughness scale.
| Arm | Type | Receives |
|---|---|---|
| Mindfulness-Based Intervention in Generation Z Nursing Students During Clinical Practicum | Experimental | Behavioral: Mindfulness-Based InterventionThe experimental group received mindfulness-based stress reduction intervention for 8 weeks. |
| line care messages in Generation Z Nursing Students During Clinical Practicum | No intervention | –The control group received line care messages weekly from instructors during clinical practicum. |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- (1) Nursing students during clinical practicum (2) Clear consciousness.
Key exclusion criteria (2 listed)
- -(1) Students diagnosed with schizophrenia, anxiety, depression or affective psychosis.
- (2)Taking anti-anxiety medicine treatment or anti-depressant medicine treatment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mindfulness-Based InterventionAlso: line care messagesMindfulness-based stress reduction interventions include: breathing awareness, loving-kindness meditation, body scan, walking meditation, sitting body awareness, eating meditation, and deep breathing exercises. | Behavioural | Mindfulness-Based Intervention in Generation Z Nursing Students During Clinical Practicum |
Primary outcome
Mental Health
Time frame: Pre-intervention(T0)、Two week after clinical practium begins (T1)、Four week after clinical practium begins(T2)、Two months after clinical practium(T3)
Psychological Well-Being Scale (PWBS-18) : Ryff \& Keyes (1995) proposed that happiness is not only a happy psychological experience, but also a perfect and true performance through one's own efforts. The original scale has 6 facets and 25 questions.
Anxiety, Depression, Stress
Time frame: Pre-intervention(T0)、Two week after clinical practium begins (T1)、Four week after clinical practium begins(T2)、Two months after clinical practium(T3)
Depression, Anxiety and Stress Scale - 21 Items (DASS-21)：Developed by scholars at the University of New South Wales in Australia in 1995, it is an internationally authoritative psychological stress assessment tool. It uses a short version of 21 questions to assess common depressive emotions such as depression, anxiety, and stress. There are 21 questions in total, which combine subjective The degree of various induced emotional states is used as an evaluation index, using a 4-point scale, where 1 means not consistent, 2 means sometimes consistent, 3 means usually consistent, and 4 means always consistent.
1 secondary outcome
Resilience
Time frame: Pre-intervention(T0)、Two week after clinical practium begins (T1)、Four week after clinical practium begins(T2)、Two months after clinical practium(T3)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Apr 2026.
- Results publication: PubMed 37264378Dong C, Xia L, Zhao C, Zhang X, He J, Zhang G, Zhang J. Prospective association between perceived stress and anxiety among nursing college students: the moderating roles of career adaptability and professional commitment. BMC Psychiatry. 2023 Jun 1;23(1):388. doi: 10.1186/s12888-023-04887-6.
- Results publication: PubMed 35318676Gurdil Yilmaz S, Yildiz Karadeniz E, dem Lafci D. Clinical-practice stress levels and factors affecting these on first-year nursing students. Perspect Psychiatr Care. 2022 Oct;58(4):3009-3015. doi: 10.1111/ppc.13070. Epub 2022 Mar 22.
- Results publication: PubMed 28103700O'Driscoll M, Byrne S, Mc Gillicuddy A, Lambert S, Sahm LJ. The effects of mindfulness-based interventions for health and social care undergraduate students - a systematic review of the literature. Psychol Health Med. 2017 Aug;22(7):851-865. doi: 10.1080/13548506.2017.1280178. Epub 2017 Jan 19.
- Results publication: PubMed 35488858Uysal N, Caliskan BB. The effects of mindfulness-based stress reduction on mindfulness and stress levels of nursing students during first clinical experience. Perspect Psychiatr Care. 2022 Oct;58(4):2639-2645. doi: 10.1111/ppc.13104. Epub 2022 Apr 30.
- Individual participant dataSharing planned: No. This study is unwilling to share research data because of confidentiality, privacy protection, legal restrictions, or terms of funding. Additionally, the inability to handle shared data requires additional time and resources to process and manage
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Chih-yin Chien, master study chair
MacKay Junior College of Medicine, Nursing, and Management
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mindfulness-Based Intervention in people with Mental Health and Anxiety, run by National Taipei University of Nursing and Health Sciences at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mental Health (time frame: Pre-intervention(T0)、Two week after clinical practium begins (T1)、Four week after clinical practium begins(T2)、Two months after clinical practium(T3)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06392100, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Apr 2026.