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Asthma; StatusNCT06407011

Effects of Swedish Massage Prior Circuit Breathing Training on Asthma

A study testing Swedish massage prior circuit breathing training group (SBT) and Circuit breathing training group (CBT) in people with Asthma; Status, run by Chulalongkorn University at 1 site in Thailand.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The objective of this study was to determine the effects of Swedish massage prior circuit breathing training on asthma control and respiratory function in patients with asthma. Read more about this study

Who is it for?
Ages 20 to 65 years
Conditions the study is for
Asthma; Status
What is being tested?
Swedish massage prior circuit breathing training group (SBT) and Circuit breathing training group (CBT)
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
30 participants
Where
1 siteThailand
Study dates
5 May 2024to 30 Sep 2024
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 65 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Being a male or female patient with asthma who is between 20 and 65 years old.
  • Being a patient who has been diagnosed by a doctor with asthma for at least 6 months.
  • The severity of the disease has been assessed at levels 2 to 4, meaning the volume of air expelled in the first second of breathing quickly and with full force (Forced Expiratory Volume in one second; FEV1) is between 80% and 30% on the date of data collection. This has been certified by a doctor, and the patient is using medication according to the normal treatment plan.
  • Must not have other respiratory diseases such as tuberculosis, lung cancer, emphysema, chronic obstructive pulmonary disease (COPD), etc.
  • Should not have received exercise training for more than 20 minutes at a time, 3 days/week, or more in the past 6 months before participating in the research.
  • Having no communication problems.
  • The sample volunteers to participate in the research and agrees to sign the consent form to participate in the research.

Who cannot join

  • Being a patient who has a history of asthma caused by exercise (Exercise-Induced Asthma).
  • In case of a force majeure event that makes it impossible to continue participating in the research, such as injury from an accident or illness, etc.
  • Participating in less than 80 percent of the training sessions (28 times out of 36 times) for the breathing training group and the group that practiced breathing together with massage.
  • Unwillingness to continue participating in the research.

Trial locations and contacts

1 site in 1 country.

Thailand1 site
  • Faculty of Sports Science, Chulalongkorn University

    Pathum Wan, Bangkok, 10330

Other trials in Thailand

About this study

Official title: Effects of Swedish Massage Prior Circuit Breathing Training on Asthma Control and Respiratory Function in Patients With Asthma

The objective of this study was to determine the effects of Swedish massage prior circuit breathing training on asthma control and respiratory function in patients with asthma.

Read the detailed description

Thirty patients with asthma aged 20-65 years were randomized into 3 groups: the control group (CON; n=10), the Circuit Breathing Training group (CBT; n=10), and the Swedish Massage prior to Circuit Breathing Training group (SBT; n=10). Participants in the CON group carried out their daily routine without receiving any training program. The CBT group received circuit breathing training sessions lasting thirty minutes each, three times a week for twelve weeks, while the SBT group received a Swedish massage (20 minutes) before circuit breathing exercises (30 minutes) three times a week for twelve weeks. Physiological data, pulmonary function, respiratory muscle strength, cytokine levels, Asthma Control Test scores, Visual Analogue Scale scores, chest expansion, and muscle flexibility variables were analyzed during the pre-test, post-test at 6 weeks, and post-tests at 12 weeks. Two-way repeated measures ANOVA was used to compare the variables between each test and between groups. Statistical significance was defined as p < .05.

Conditions
Asthma; Status
Being tested
Control, Swedish massage prior circuit breathing training group (SBT), Circuit breathing training group (CBT)
Keywords
Asthma, Circuit breathing, Swedish massage, Pulmonary function, Asthma control
Medical subject headings
Asthma

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • ControlOther

    The CON group did not have any intervention but usual care.

  • Swedish massage prior circuit breathing training group (SBT)Other

    Participants Swedish massage prior circuit breathing training 3 days/week, 12 weeks. They perform Swedish massage using techniques such as stroking, kneading, and tapping the upper muscle area of the body for 20 minutes per day. Then, they do circuit breathing exercises for about 30 minutes per day, comprising 3 sets of 4 breathing exercises (triflow, power breath, windmill, and balloon blowing), with 1-minute rest between each exercise and 2 minutes between each set.

  • Circuit breathing training group (CBT)Other

    Participants perform circuit breathing exercises for about 30 minutes per day, 3 days/week, 12 weeks, comprising 3 sets of 4 breathing exercises (triflow, power breath, windmill, and balloon blowing), with 1-minute rest between each exercise and 2 minutes between each set.

Study groups in NCT06407011
Study groupRoleWhat they receive
ControlSham comparatorThe CON group did not have any intervention but usual care.
Receives: Other: Control
Swedish massage prior circuit breathing training group (SBT)ExperimentalParticipants Swedish massage prior circuit breathing training 3 days/week, 12 weeks. They perform Swedish massage using techniques such as stroking, kneading, and tapping the upper muscle area of the body for 20 minutes per day. Then, they do circuit breathing exercises for about 30 minutes per day, comprising 3 sets of 4 breathing exercises (triflow, power breath, windmill, and balloon blowing), with 1-minute rest between each exercise and 2 minutes between each set.
Receives: Other: Swedish massage prior circuit breathing training group (SBT)
Circuit breathing training group (CBT)ExperimentalParticipants perform circuit breathing exercises for about 30 minutes per day, 3 days/week, 12 weeks, comprising 3 sets of 4 breathing exercises (triflow, power breath, windmill, and balloon blowing), with 1-minute rest between each exercise and 2 minutes between each set.
Receives: Other: Circuit breathing training group (CBT)

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Asthma Control Test : ACT

    The Asthma Control Test (ACT) consists of 5 questions designed to assess asthma symptoms over the past 4 weeks. A score out of 25 points is given, with a high score indicating good asthma control. A score lower than 20 points indicates that the disease is not well controlled.

    Measured: Change from baseline Asthma Control Test : ACT at 6 and 12 weeks.

  2. The Mini Asthma Quality of Life Questionnaire: Mini AQLQ

    The Mini Asthma Quality of Life Questionnaire (Mini AQLQ) aims to assess changes in life satisfaction related to health status over the past 2 weeks. It consists of a total of 15 questions divided into 4 areas: Signs and symptoms: 5 items, Environmental management: 3 items, Emotion management: 3 items, and Performance of daily activities: 4 items.

    Measured: Change from baseline The Mini Asthma Quality of Life Questionnaire: Mini AQLQ at 6 and 12 weeks.

  3. Pulmonary function (Forced vital capacity; FVC)

    The participants were instructed to sit on a chair and wear a nose clip. The researcher provided them with a detailed set of instructions to ensure they performed the maneuver correctly according to guidelines of the American Thoracic Society (ATS). Prior to demonstrating forced inspiration and expiration, the participants were asked to perform three cycles of slow normal breathing as part of the FVC maneuver. FVC will be reported in liter (L).

    Measured: Change from baseline FVC at 6 and 12 weeks.

  4. Pulmonary function (Forced Expiratory Volume in one second; FEV1)

    The participants were instructed to sit on a chair and wear a nose clip. The researcher provided them with a detailed set of instructions to ensure they performed the maneuver correctly according to guidelines of the American Thoracic Society (ATS). Prior to demonstrating forced inspiration and expiration, the participants were asked to perform three cycles of slow normal breathing as part of the FVC maneuver. FEV1 (L) will be reported in liter (L).

    Measured: Change from baseline FEV1 at 6 and 12 weeks.

  5. Pulmonary function (The ratio of the forced expiratory volume in the first one second to the forced vital capacity of the lungs; FEV1/FVC)

    The participants were instructed to sit on a chair and wear a nose clip. The researcher provided them with a detailed set of instructions to ensure they performed the maneuver correctly according to guidelines of the American Thoracic Society (ATS). Prior to demonstrating forced inspiration and expiration, the participants were asked to perform three cycles of slow normal breathing as part of the FVC maneuver. FEV1/FVC will be reported in percent (%).

    Measured: Change from baseline FEV1/FVC at 6 and 12 weeks.

  6. Pulmonary function (Maximal voluntary ventilation; MVV)

    The participants were instructed to sit on a chair and wear a nose clip. The researcher provided them with a detailed set of instructions to ensure they performed the maneuver correctly according to guidelines of the American Thoracic Society (ATS). During the MVV maneuver, participants were instructed to demonstrate in rapid and forceful inhalation and exhalation for a duration of 10 seconds. MVV will be reported in liter per minute (L/min).

    Measured: Change from baseline MVV at 6 and 12 weeks.

  7. Respiratory muscle strength

    Respiratory muscle strength was evaluated by measuring Maximal Inspiratory Pressure (MIP) and Maximal Expiratory Pressure (MEP) in centimeters of water (cmH2O). The participants were seated and utilized a portable handheld mouth pressure meter (MicroRPM), along with a nose clip. To assess MIP, participants were instructed to exhale until they emptied their lungs at the point of functional residual capacity (FRC). Participants held the device to their mouth and forcefully inhaled for 1-2 seconds. For the measurement of MEP, participants were directed to inhale until their lungs were completely filled with air, starting from the total lung capacity (TLC) point. Participants were asked to maintain the device on their mouth and forcefully exhaled for 1-2 seconds.

    Measured: Change from baseline Respiratory muscle strength at 6 and 12 weeks.

Secondary outcomes (7)
  1. Fractional exhaled nitric oxide

    Participants inhaled deeply for two to three seconds before exhaling slowly. Normally, it took 10 seconds to exhale.

    Measured: Change from baseline Fractional exhaled nitric oxide at 6 and 12 weeks.

  2. Blood chemical data test

    Draw 10 milliliters of blood to analyze blood biochemistry, including interleukin-4 (IL-4), interleukin-5 (IL-5), and interleukin-13 (IL-13).

    Measured: Change from baseline concentration of cytokines in serum of interleukin-4 (IL-4), interleukin-5 (IL-5), and interleukin-13 (IL-13) at 6 and 12 weeks.

  3. Chest expansion

    The subjects were asked to sit upright with their hands on their hips. They were then asked to exhale fully and inhale fully. The researcher will use a tape measure to measure the expansion of the chest at various levels, including the upper chest at axillary line, midway between the 2nd and 4th ribs, the middle chest at the level of xiphoid process, midway between Ribs 4 - 6, and the lower thorax at the level of the 10th rib.

    Measured: Change from baseline chest expansion at 6 and 12 weeks.

  4. Trunk flexion

    Ask the research participant to stand upright. Then, the researcher will take a tape measure and measure the C7 - S1 position and record the measured value. Next, instruct the participants to slowly bend their torso without bending their knees as much as possible, and then read the measurements on the measuring tape and record them.

    Measured: Change from baseline trunk flexion at 6 and 12 weeks.

  5. Trunk extension

    The participants stood up straight, then the researcher took a tape measure and measured the positions C7 - S1, recording the measured values. The subjects were then instructed to slowly stretch their torso as much as possible without stretching their hips or rotating their torso, and then to read the measurement after stretching their back.

    Measured: Change from baseline trunk extension at 6 and 12 weeks.

  6. Neck flexion

    The participant stood upright, and the researcher placed the goniometer's pivot point over the participant's ear. Then, instruct the participant to slowly bow his or her head with the chin as close to the neck as possible, while placing the goniometer over the tip of the participant's nose. Measure and record the data.

    Measured: Change from baseline neck flexion at 6 and 12 weeks.

  7. Neck extension

    The participant tilted their head as far back as possible. Then, the researcher placed the goniometer's pivot point over the participant's ear, extending the goniometer over the tip of the participant's nose. Measure and record the data.

    Measured: Change from baseline neck extension at 6 and 12 weeks.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted9 May 2024
  2. Study start5 May 2024
  3. Primary completion10 Aug 2024
  4. Study completion30 Sep 2024

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
30 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06407011
Sponsor's protocol ID
EX PHYSIO SPSC 10
Status last verified
Aug 2024
First submitted
6 May 2024
Last updated
8 Oct 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing Swedish massage prior circuit breathing training group (SBT) and Circuit breathing training group (CBT) in people with Asthma; Status, run by Chulalongkorn University at 1 site in Thailand.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 7 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 8 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Asthma Control Test : ACT (time frame: Change from baseline Asthma Control Test : ACT at 6 and 12 weeks.). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Oct 2026.

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