Postoperative PainNCT06412796
Postoperative Analgesic Effects of Subcostal Transversus Abdominis Plane Block Versus External Oblique Intercostal Block on Patients Undergoing Gastrectomy
A study testing subcostal TAP and EOIPB in people with Postoperative Pain and Analgesia, run by TC Erciyes University at 1 site in Turkey (Türkiye).
Trial summary
Open Gastrectomy surgery is a big surgery with upper umbilical median incision where the postoperative pain is occur frequently. pain managements of this surgery with intravenous opioid analgesics are currently standard approach. Read more about this study
- Who is it for?
- Ages 18 to 90 years
- Conditions the study is for
- Postoperative Pain, Analgesia
- What is being tested?
- subcostal TAP and EOIPB
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 26 Jun 2024to 25 Mar 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 90 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- patients who have diagnosed Gastric Cancer and undergoing Gastric resection
- patients accepted to participate for study
Who cannot join
- parients that not agreed for the study
- patients who undergoing for second operation at the same surgery incision
- patient that have chronic pains and multiple drugs using
- patients that have psychiatric disorders
- bariatric surgery
- patients with allergics for local anaesthetics
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of Postoperative Analgesic Effectiveness of Subcostal Transversus Abdominis Plane Block Versus External Oblique Intercostal Block on Patients With Gastric Cancer Undergoing Gastrectomy
Open Gastrectomy surgery is a big surgery with upper umbilical median incision where the postoperative pain is occur frequently. pain managements of this surgery with intravenous opioid analgesics are currently standard approach. but its side effects as sedation, decreased bowel movement and respiratory depression are limiting its use. so local anesthesia done with regional block methods provides good analgesia after surgery that decrease use of opioid analgesics. in this study we intend to compare subcostal TAP block with external oblique intercostal block
Read the detailed description
in our study, we include the patients who has diagnosed Gastric Cancer and going to open gastrectomy surgery. this surgery performing with initial upper umbilical median incision of abdomen and then removing part or all of the stomach organ, which is cause postoperative pain on all abdominal area and affect the patient's recovery and morbidity. perioperative pain management is also important part of recovery after surgery. intravenous morphine using is part of protocols in analgesics. lately opioid free analgesia is aimed because of opioids side effects such as sedation, respiratory depression and decrease in bowel movement affect patients' recovery and duration in hospital. in this way regional and local anesthetics methods are getting more interested in pain management. To ensure the analgesic effects of the upper umbilical median incision area we planned to perform External Oblique Intercostal (EOI) block and Subcostal Transversus Abdominis Plane (SCTAP) block. To get better results we performed both blocks with Ultrasound Guided Imaging and injected bilateral with 15-20 ml of diluted local anesthetics on each side before the surgery. We divide patients into two groups: Group 1: the patients who get SCTAP block and Group 2: the patients who get EOI block. After the general anesthesia and intubation of patient we clean the abdominal area within antiseptic to perform injection before the surgery is began. In Group 1, SCTAP Block is performing by USG probe positioned on the anterior abdominal wall immediately inferior to the costal margin and then needle advanced to 2 to 3 cm lateral to the aponeurosis of the external oblique muscles, internal oblique muscles, and transversus abdominis in the TAP. Saline 0.5mL was injected to determine the position of the transverse fascia and 15-20 ml local anesthetics injected both in right and left sides of abdomen. In Group 2, EOI block is performed by placing the US probe in paramedian sagittal orientation at the T6-7 level and visualizing the external oblique and intercostal muscles. Local anesthetics inject the under the external oblique muscle. After the surgery patient controlled analgesia (PCA) is given to patients if there will not enough analgesic management confirmed. Pain assessment will be evaluated with the visual pain scale at 2/6/12/24 hours after surgery completed.
- Conditions
- Postoperative Pain, Analgesia
- Being tested
- subcostal TAP, EOIPB
- Keywords
- SCTAP, External Oblique Intercostal block, postoperative analgesia
- Medical subject headings
- Pain, Postoperative, Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
subcostal TAPProcedure or surgery
SCTAP Block is performing by USG probe positioned on the anterior abdominal wall immediately inferior to the costal margin and then needle advanced to 2 to 3 cm lateral to the aponeurosis of the external oblique muscles, internal oblique muscles, and transversus abdominis in the TAP. Saline 0.5mL was injected to determine the position of the transverse fascia and 15-20 ml local anesthetics injected both in right and left sides of abdomen.
EOIPBProcedure or surgery
EOI block is performed by placing the US probe in paramedian sagittal orientation at the T6-7 level and visualizing the external oblique and intercostal muscles. Local anesthetics inject the under the external oblique muscle.
| Study group | Role | What they receive |
|---|---|---|
| Subcostal Transversus Abdominis Plane (SCTAP) block. | Active comparator | SCTAP Block is performing by USG probe positioned on the anterior abdominal wall immediately inferior to the costal margin and then needle advanced to 2 to 3 cm lateral to the aponeurosis of the external oblique muscles, internal oblique muscles, and transversus abdominis in the TAP. Saline 0.5mL was injected to determine the position of the transverse fascia and 15-20 ml local anesthetics injected both in right and left sides of abdomen. Receives: Procedure: subcostal TAP |
| External Oblique Intercostal (EOI) block | Active comparator | EOI block is performed by placing the US probe in paramedian sagittal orientation at the T6-7 level and visualizing the external oblique and intercostal muscles. Local anesthetics inject the under the external oblique muscle. Receives: Procedure: EOIPB |
What is being measured
The primary outcome is the main question the study is designed to answer.
Need of morphine analgesia
postoperatively monitoring of patients that need analgesics by morphine consumption using a patient contral analgesics device that record amount of used and wanted analgesics by patients themselves
Measured: 24 hours
patients pain scales
asking patients for pain at postoperative period by visual analog scale and score accordingly
Measured: 24 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 May 2024
- Study start26 Jun 2024
- Primary completion25 Feb 2025
- Study completion25 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- More trials run by TC Erciyes UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- TC Erciyes University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ayse Ulgey, TC Erciyes University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06412796
- Sponsor's protocol ID
- 2023/600
- Status last verified
- Aug 2026
- First submitted
- 9 May 2024
- Last updated
- 4 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Postoperative Analgesic Effectiveness of Subcostal Transversus Abdominis Plane Block Versus External Oblique Intercostal Block on Patients With Gastric Cancer Undergoing Gastrectomy
- ClinicalTrials.gov ID
- NCT06412796
- Acronym / sponsor ID
- 2023/600
- Conditions
- Postoperative Pain, Analgesia
- Keywords
- SCTAP, External Oblique Intercostal block, postoperative analgesia
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- TC Erciyes UniversityUniversity, hospital or other
- Study start
- 26 Jun 2024 (actual)
- Primary completion
- 25 Feb 2025 (actual)
- Study completion
- 25 Mar 2025 (actual)
- First posted
- 14 May 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Open Gastrectomy surgery is a big surgery with upper umbilical median incision where the postoperative pain is occur frequently. pain managements of this surgery with intravenous opioid analgesics are currently standard approach. but its side effects as sedation, decreased bowel movement and respiratory depression are limiting its use. so local anesthesia done with regional block methods provides good analgesia after surgery that decrease use of opioid analgesics. in this study we intend to compare subcostal TAP block with external oblique intercostal block
Detailed description
in our study, we include the patients who has diagnosed Gastric Cancer and going to open gastrectomy surgery. this surgery performing with initial upper umbilical median incision of abdomen and then removing part or all of the stomach organ, which is cause postoperative pain on all abdominal area and affect the patient's recovery and morbidity. perioperative pain management is also important part of recovery after surgery. intravenous morphine using is part of protocols in analgesics. lately opioid free analgesia is aimed because of opioids side effects such as sedation, respiratory depression and decrease in bowel movement affect patients' recovery and duration in hospital. in this way regional and local anesthetics methods are getting more interested in pain management. To ensure the analgesic effects of the upper umbilical median incision area we planned to perform External Oblique Intercostal (EOI) block and Subcostal Transversus Abdominis Plane (SCTAP) block. To get better results we performed both blocks with Ultrasound Guided Imaging and injected bilateral with 15-20 ml of diluted local anesthetics on each side before the surgery. We divide patients into two groups: Group 1: the patients who get SCTAP block and Group 2: the patients who get EOI block. After the general anesthesia and intubation of patient we clean the abdominal area within antiseptic to perform injection before the surgery is began. In Group 1, SCTAP Block is performing by USG probe positioned on the anterior abdominal wall immediately inferior to the costal margin and then needle advanced to 2 to 3 cm lateral to the aponeurosis of the external oblique muscles, internal oblique muscles, and transversus abdominis in the TAP. Saline 0.5mL was injected to determine the position of the transverse fascia and 15-20 ml local anesthetics injected both in right and left sides of abdomen. In Group 2, EOI block is performed by placing the US probe in paramedian sagittal orientation at the T6-7 level and visualizing the external oblique and intercostal muscles. Local anesthetics inject the under the external oblique muscle. After the surgery patient controlled analgesia (PCA) is given to patients if there will not enough analgesic management confirmed. Pain assessment will be evaluated with the visual pain scale at 2/6/12/24 hours after surgery completed.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Subcostal Transversus Abdominis Plane (SCTAP) block. | Active comparator | Procedure: subcostal TAPSCTAP Block is performing by USG probe positioned on the anterior abdominal wall immediately inferior to the costal margin and then needle advanced to 2 to 3 cm lateral to the aponeurosis of the external oblique muscles, internal oblique muscles, and transversus abdominis in the TAP. Saline 0.5mL was injected to determine the position of the transverse fascia and 15-20 ml local anesthetics injected both in right and left sides of abdomen. |
| External Oblique Intercostal (EOI) block | Active comparator | Procedure: EOIPBEOI block is performed by placing the US probe in paramedian sagittal orientation at the T6-7 level and visualizing the external oblique and intercostal muscles. Local anesthetics inject the under the external oblique muscle. |
Who may qualify
- Ages
- 18 to 90 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- patients who have diagnosed Gastric Cancer and undergoing Gastric resection
- patients accepted to participate for study
Key exclusion criteria (6 listed)
- parients that not agreed for the study
- patients who undergoing for second operation at the same surgery incision
- patient that have chronic pains and multiple drugs using
- patients that have psychiatric disorders
- bariatric surgery
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| subcostal TAPSCTAP Block is performing by USG probe positioned on the anterior abdominal wall immediately inferior to the costal margin and then needle advanced to 2 to 3 cm lateral to the aponeurosis of the external oblique muscles, internal oblique muscles, and transversus abdominis in the TAP. Saline 0.5mL was injected to determine the position of the transverse fascia and 15-20 ml local anesthetics injected both in right and left sides of abdomen. | Procedure or surgery | Subcostal Transversus Abdominis Plane (SCTAP) block. |
| EOIPBEOI block is performed by placing the US probe in paramedian sagittal orientation at the T6-7 level and visualizing the external oblique and intercostal muscles. Local anesthetics inject the under the external oblique muscle. | Procedure or surgery | External Oblique Intercostal (EOI) block |
Primary outcome
Need of morphine analgesia
Time frame: 24 hours
postoperatively monitoring of patients that need analgesics by morphine consumption using a patient contral analgesics device that record amount of used and wanted analgesics by patients themselves
patients pain scales
Time frame: 24 hours
asking patients for pain at postoperative period by visual analog scale and score accordingly
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing subcostal TAP and EOIPB in people with Postoperative Pain and Analgesia, run by TC Erciyes University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Need of morphine analgesia (time frame: 24 hours). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Aug 2026.