AzTrials
AzTrials

Alcohol DrinkingNCT06422299

Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples

A study testing Online, couples-based intervention in people with Alcohol Drinking and Cannabis Use, run by University of Washington.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts
Official record
Search all trials

Trial summary

The goal of this clinical trial is to develop and test a brief online intervention to reduce alcohol and cannabis misuse and improve healthy relationship skills among young adult couples. Read more about this study

Who is it for?
Ages 18 to 29 yearsHealthy volunteers can take part
Conditions the study is for
Alcohol Drinking, Cannabis Use, Couples
What is being tested?
Online, couples-based intervention
Could I receive a placebo?
No, everyone receives an active treatment
How many people
60 participants
Where
No sites listed yet
Study dates
1 Oct 2026to 1 Oct 2027
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 29 years
  • All sexes
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • Both partners in the couple are 18-29 years old
  • In a committed romantic relationship (e.g., dating seriously, cohabiting, married) with each other for at least 3 months
  • Face-to-face contact their partner at least 5 days per week
  • Live in Washington State
  • Have a valid email address and access to a cell phone
  • Report alcohol and cannabis co-use at least three times in the past month
  • Willingness to: complete online surveys during the allotted time frames, receive text messages and emails from the project, complete a baseline session, and participate during the same time period as their partner

Who cannot join

  • Couples who endorse any perpetration or receipt of severe interpersonal aggression during screening will be excluded and provided with resources

Trial locations and contacts

No sites are listed yet. Contact the study team or a site near you to ask about taking part.

Katherine Walukevich-Dienst, PhD contact

508-282-0413

kwd1@uw.edu

Hana Basu, BA contact

425-372-6459

About this study

Official title: Developing and Testing an Online Intervention for Decreasing Alcohol and Cannabis Misuse and Increasing Healthy Relationship Skills Among Young Adult Couples: A Comprehensive Mixed-methods Approach

The goal of this clinical trial is to develop and test a brief online intervention to reduce alcohol and cannabis misuse and improve healthy relationship skills among young adult couples. The main questions it aims to answer are:

  • Will the intervention be feasible and acceptable to young adult couples?
  • Will the intervention demonstrate initial efficacy in reducing risky substance use and increasing relationship functioning?
Read more

Eligible couples will complete a virtual baseline session and be randomized to intervention condition (online intervention with 3-5 weeks of self-paced modules) or control condition (no intervention). Couples will complete two follow-up surveys (post-assessment - approximately 5 weeks after baseline, 3-month). Couples in the control condition will be offered the intervention after 3-month follow-up.

Researchers will compare intervention and control groups to see if there there is a difference between the groups on substance misuse and relationship functioning at post-assessment and 3-month follow-up.

Being tested
Online, couples-based intervention
Keywords
alcohol use, cannabis use, couples, healthy relationships, young adults
Medical subject headings
Alcohol Drinking

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Online, couples-based interventionBehavioural

    During Phase 1 of the present study, the intervention will be iteratively developed using a rigorous, user-centered design approach through integration of knowledge gained from Phase 1 dyadic analyses and qualitative interviews, and existing gold-standard treatments for substance use among couples, including Integrative Behavioral Couples Therapy (IBCT; Christensen \& Doss, 2016) and Behavioral Couples Therapy for Alcohol (ABCT; McCrady et al, 1995) and substance use brief interventions for young adults (Halladay, et al., 2019; Tanner-Smith et al., 2015).

Study groups in NCT06422299
Study groupRoleWhat they receive
Online, couples-based interventionExperimentalA novel, brief online intervention for young adults community couples who engage in alcohol and cannabis co-use.
Receives: Behavioral: Online, couples-based intervention
Assessment-only controlNo interventionCouples in the control condition will not receive an intervention.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Heavy episodic and high intensity drinking

    Alcohol use - number of days in the past month participant engaged in heavy episodic drinking (4+/5+ drinks in one occasion for women/men) and high intensity drinking (8+/10+ drinks in one occasion for women/men)

    Measured: Screening, baseline, approximately 5 weeks after baseline, 3-month followup

  2. Daily Drinking Questionnaire (DDQ)

    Alcohol use - Average total drinks per week will be calculated as the sum of the total number of drinks reported.

    Measured: Screening, baseline, approximately 5 weeks after baseline, 3-month followup

  3. Daily Marijuana Questionnaire (DMQ)

    Cannabis use - Average total hours high from cannabis per week will be calculated as the sum of the total hours high reported

    Measured: Screening, baseline, approximately 5 weeks after baseline, 3-month followup

  4. Intensity of Marijuana Use

    Cannabis use intensity - Average number of times used cannabis per day will be calculated as the mean number of times participant reports using cannabis per each day of a typical week in the past month

    Measured: Screening, baseline, approximately 5 weeks after baseline, 3-month followup

  5. Perceived Program Effects on Healthy Relationship Self-Efficacy items

    Healthy relationship self-efficacy - 3 items assessing perceived intervention impacts on healthy relationship self-efficacy scored 0=strongly disagree to 5=strongly agree. Scores will be summed, total scores will range from 0 to 15, with higher scores indicating greater healthy relationship self-efficacy

    Measured: Screening, baseline, approximately 5 weeks after baseline, 3-month followup

  6. Couples Satisfaction Index

    Relationship satisfaction - sum of 4 items ranges from 0 to 21, higher scores indicate greater relationship satisfaction

    Measured: Screening, baseline, approximately 5 weeks after baseline, 3-month followup

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted20 May 2024
  2. Study start1 Oct 2026 (estimated)
  3. Primary completion1 Oct 2027 (estimated)
  4. Study completion1 Oct 2027 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Prevention
Allocation
Randomised
Intervention model
Parallel groups
Masking
None (open label)
Enrolment
60 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06422299
Sponsor's protocol ID
STUDY00017992
Other IDs
K23AA031034-01
Status last verified
Jul 2026
First submitted
8 Feb 2024
Last updated
8 Jul 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Publications

  • Patrick ME. A Call for Research on High-Intensity Alcohol Use. Alcohol Clin Exp Res. 2016 Feb;40(2):256-9. doi: 10.1111/acer.12945. No abstract available.

    PubMed 26842244

  • Collins RL, Parks GA, Marlatt GA. Social determinants of alcohol consumption: the effects of social interaction and model status on the self-administration of alcohol. J Consult Clin Psychol. 1985 Apr;53(2):189-200. doi: 10.1037//0022-006x.53.2.189. No abstract available.

    PubMed 3998247

  • Lee CM, Kilmer JR, Neighbors C, Atkins DC, Zheng C, Walker DD, Larimer ME. Indicated prevention for college student marijuana use: a randomized controlled trial. J Consult Clin Psychol. 2013 Aug;81(4):702-9. doi: 10.1037/a0033285. Epub 2013 Jun 10.

    PubMed 23750464

  • Patrick ME, Veliz PT, Terry-McElrath YM. High-intensity and simultaneous alcohol and marijuana use among high school seniors in the United States. Subst Abus. 2017 Oct-Dec;38(4):498-503. doi: 10.1080/08897077.2017.1356421. Epub 2017 Jul 20.

    PubMed 28726580

  • Scott ME, Moore KA, Fish H, Benedetti A, Erikson S. OPRE Report #2015-65a. Prepared by Child Trends. Washington, DC: Office of Planning, Research and Evaluation, Administration for Children and Families, U.S. Department of Health and Human Services. 2015. https://www.acf.hhs.gov/sites/default/files/documents/b_hmre_recommended_outcome_measures_for_adolescents_508_0.pdf

  • Funk JL, Rogge RD. Testing the ruler with item response theory: increasing precision of measurement for relationship satisfaction with the Couples Satisfaction Index. J Fam Psychol. 2007 Dec;21(4):572-83. doi: 10.1037/0893-3200.21.4.572.

    PubMed 18179329

Questions about this trial

What is this clinical trial studying?

A study testing Online, couples-based intervention in people with Alcohol Drinking and Cannabis Use, run by University of Washington.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 7 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 8 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Katherine Walukevich-Dienst, PhD (508-282-0413, kwd1@uw.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Heavy episodic and high intensity drinking (time frame: Screening, baseline, approximately 5 weeks after baseline, 3-month followup). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06422299, which also lists 6 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jul 2026.

AzTrials uses cookies for analytics and advertising. You can accept or reject them; the site works either way. Privacy Policy.

Free account

Keep searching with a free account

You’ve used your 3 free searches for this session. Log in or create a free AzTrials account to keep searching clinical trials and save the ones you want to follow.

Create a free accountLog in