CariesNCT06438926
Prevalence of Dental Caries in Patients With Dental Crowding
An observational study of Caries, run by Cairo University.
Trial summary
Dental crowding causes limited access for the toothbrush, and the natural cleansing effect of the teeth by the tongue and saliva is also limited. This malposition allows for prolonged food accumulation, bacterial and plaque retention, which are important factors for the initiation and progression of dental caries. Read more about this study
- Who is it for?
- Ages 12 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Caries
- How many people
- 325 participants
- Where
- No sites listed yet
- Study dates
- Sep 2024to Nov 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 to 30 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Study population: Young adults range from 12-30 years,Females or Males with anterior dental crowding.
Who may be able to join
- Young adults range from 12-30 years.
- Females or Males.
- Anterior dental crowding.
Who cannot join
- Patients undergoing orthodontic treatment.
- Patients who have any missing anterior teeth.
- Patients who have any physical or mental disabilities.
About this study
Dental crowding causes limited access for the toothbrush, and the natural cleansing effect of the teeth by the tongue and saliva is also limited. This malposition allows for prolonged food accumulation, bacterial and plaque retention, which are important factors for the initiation and progression of dental caries.
Read the detailed description
Dental crowding causes limited access for the toothbrush, and the natural cleansing effect of the teeth by the tongue and saliva is also limited. This malposition allows for prolonged food accumulation, bacterial and plaque retention, which are important factors for the initiation and progression of dental caries .
According to the World Health Organization, the main dental problems should be subjected to periodic epidemiological surveys. Knowledge of a population's epidemiological situation is vital for planning and providing prevention and treatment services .
However, only few studies investigated the correlation between caries and crowding.Yet, their findings were inconsistent and still contradictory.
Previous systematic review concluded that there is no reliable evidence regarding the association between dental caries and crowding and further studies with adequate sample size are required. Another systematic review found an association between caries and crowding but only in the adolescent group .
As caries is a preventable disease, improving the understanding of this possible association would be beneficial for dental practitioners, public health policy makers and the general population as it will help in the application of medical model.
This Cross-sectional study can detect one of predictors of dental caries early as crowding so the dentists can prohibit future carious lesions \& help in caries prevention through orthodontic treatment \& proper oral hygiene measures.
- Conditions
- Caries
What is being measured
The primary outcome is the main question the study is designed to answer.
Dental Caries
DMF index developed by WHO health organization using numbered scores
Measured: throughout study completion an average of 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jun 2024
- Study startSep 2024 (estimated)
- Primary completionSep 2025 (estimated)
- Study completionNov 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for CariesStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 325 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Reem Mohamed Mossaad, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06438926
- Sponsor's protocol ID
- Caries with dental crowding
- Status last verified
- May 2024
- First submitted
- 20 May 2024
- Last updated
- 3 Jun 2024
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Hafez HS, Shaarawy SM, Al-Sakiti AA, Mostafa YA. Dental crowding as a caries risk factor: a systematic review. Am J Orthod Dentofacial Orthop. 2012 Oct;142(4):443-50. doi: 10.1016/j.ajodo.2012.04.018.
PubMed 22999666Caplin JL, Evans CA, Begole EA. The Relationship between Caries and Malocclusion in Chinese Migrant Workers' Children in Shanghai. Chin J Dent Res. 2015;18(2):103-10.
PubMed 26167548
Study at a glance
From the registry record, last updated by the sponsor on 3 Jun 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prevalence of Dental Caries in Patients With Dental Crowding
- ClinicalTrials.gov ID
- NCT06438926
- Acronym / sponsor ID
- Caries with dental crowding
- Conditions
- Caries
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 325 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- Sep 2024 (estimated)
- Primary completion
- Sep 2025 (estimated)
- Study completion
- Nov 2025 (estimated)
- First posted
- 3 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Dental crowding causes limited access for the toothbrush, and the natural cleansing effect of the teeth by the tongue and saliva is also limited. This malposition allows for prolonged food accumulation, bacterial and plaque retention, which are important factors for the initiation and progression of dental caries.
Detailed description
Dental crowding causes limited access for the toothbrush, and the natural cleansing effect of the teeth by the tongue and saliva is also limited. This malposition allows for prolonged food accumulation, bacterial and plaque retention, which are important factors for the initiation and progression of dental caries .
According to the World Health Organization, the main dental problems should be subjected to periodic epidemiological surveys. Knowledge of a population's epidemiological situation is vital for planning and providing prevention and treatment services .
However, only few studies investigated the correlation between caries and crowding.Yet, their findings were inconsistent and still contradictory.
Previous systematic review concluded that there is no reliable evidence regarding the association between dental caries and crowding and further studies with adequate sample size are required. Another systematic review found an association between caries and crowding but only in the adolescent group .
As caries is a preventable disease, improving the understanding of this possible association would be beneficial for dental practitioners, public health policy makers and the general population as it will help in the application of medical model.
This Cross-sectional study can detect one of predictors of dental caries early as crowding so the dentists can prohibit future carious lesions \& help in caries prevention through orthodontic treatment \& proper oral hygiene measures.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 12 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
- Study population
- Young adults range from 12-30 years,Females or Males with anterior dental crowding.
Key inclusion criteria (3 listed)
- Young adults range from 12-30 years.
- Females or Males.
- Anterior dental crowding.
Key exclusion criteria (3 listed)
- Patients undergoing orthodontic treatment.
- Patients who have any missing anterior teeth.
- Patients who have any physical or mental disabilities.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Dental Caries
Time frame: throughout study completion an average of 1 year
DMF index developed by WHO health organization using numbered scores
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Jun 2024.
- Background: PubMed 22999666Hafez HS, Shaarawy SM, Al-Sakiti AA, Mostafa YA. Dental crowding as a caries risk factor: a systematic review. Am J Orthod Dentofacial Orthop. 2012 Oct;142(4):443-50. doi: 10.1016/j.ajodo.2012.04.018.
- Background: PubMed 26167548Caplin JL, Evans CA, Begole EA. The Relationship between Caries and Malocclusion in Chinese Migrant Workers' Children in Shanghai. Chin J Dent Res. 2015;18(2):103-10.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Caries, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 3 Jun 2024. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Dental Caries (time frame: throughout study completion an average of 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06438926, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Jun 2024.