HealthyNCT06449300
Effects of Different Volumes of Resistance Training
A study testing Resistance exercise-LVT, Resistance exercise-MVT and Resistance exercise-HVT in people with Healthy, run by Princess Nourah Bint Abdulrahman University at 1 site in Saudi Arabia.
Trial summary
This study explores the effects of varying volumes of resistance training on body composition, strength, peak power, and muscle thickness in untrained women over eight weeks. A randomized controlled trial involving 45 female college students assessed the outcomes across three groups: low-volume training (LVT) with… Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- Resistance exercise-LVT, Resistance exercise-MVT and Resistance exercise-HVT
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 15 participants
- Where
- 1 siteSaudi Arabia
- Study dates
- 11 Nov 2021to 11 Jan 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adult women between ages of 18 -65 years old
- Able to walk independently
- Free of any history of cardiovascular disease
- Untrained (less than 150 min of PA/week)
Who cannot join
- Intake of performance-enhancing drugs, anabolic steroids
- Any history of injury, or physiological or physical limitations that could affect the ability to perform training and physical testing in the last year.
- Those who had been RT for more than 2 months in the previous 6 months were excluded.
Trial locations and contacts
1 site in 1 country.
Saudi Arabia1 site
Princess Nourah bint Abdulrahman University
Riyadh, 11671
About this study
Official title: Effects of Different Volumes of Resistance Training on Body Composition, Peak Power, and Muscle Thickness in Untrained Healthy Women
This study explores the effects of varying volumes of resistance training on body composition, strength, peak power, and muscle thickness in untrained women over eight weeks. A randomized controlled trial involving 45 female college students assessed the outcomes across three groups: low-volume training (LVT) with three weekly sessions, moderate-volume training (MVT) with four weekly sessions, and high-volume training (HVT) with five weekly sessions. Participants were untrained, aged 18-65, and free from cardiovascular diseases or performance-enhancing drugs.
The hypothesis suggested that moderate volume training would yield optimal muscle development, considering the potential non-linear dose-response relationship where excessive training might be detrimental. Measurements included body composition, muscle thickness, and peak power through a force platform during vertical jumps.
Data analysis focused on changes in muscle thickness, strength, and body composition, with statistical significance set at p < 0.05. The study aimed to provide insights into how different training volumes affect physiological adaptations in untrained women, potentially guiding fitness regimen optimizations for similar populations.
Read the detailed description
The study aimed to investigate the effect of different resistance training volume (low-, moderate, and high) on body composition, maximal strength, peak power, and muscle thickness in untrained women over eight weeks. The study is a three-arm, randomized controlled trial, 45 female college students participated, fit the specific inclusion criteria like age between 18-65 and being untrained. Exclusion criteria included the use of performance-enhancing drugs or recent resistance training.
Participants were randomly assigned to one of three groups: low-volume training (LVT) with three sessions weekly, moderate-volume training (MVT) with four sessions weekly, and high-volume training (HVT) with five sessions weekly. Each session comprised 12 exercises. Split split-strength training method was applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts were conducted by certified trainers to ensure they were performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants were increased by 5%. In the LVT group, 3 sets of 8-12 repetitions of: between sets interval: 120 seconds (3 days/wk), in the MVT group, 3 sets of 8-12 repetitions of: between sets interval: 120 seconds (4 days/wk), in the HVT group, 3 sets of 8-12 repetitions of: between sets interval: 120 seconds exercises (5 days/wk) were performed.
Results and data analysis involved anthropometric measurements, muscle thickness via ultrasound, and peak power from the vertical jump test. Statistical significance was set at p < 0.05, and effect sizes were calculated with Partial Eta Squared values.
- Conditions
- Healthy
- Being tested
- Resistance exercise-LVT, Resistance exercise-MVT, Resistance exercise-HVT
- Keywords
- Strength training, muscle growth
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Resistance exercise-LVTOther
(low volume training - 3 sessions of 12 exercises per week)
Resistance exercise-MVTOther
(moderate volume training - 4 sessions of 12 exercises per week)
Resistance exercise-HVTOther
(high volume training - 5 sessions of 12 exercises per week)
| Study group | Role | What they receive |
|---|---|---|
| low volume (LVT) resistance training | Experimental | 3 sessions of 12 exercises per week for 8 weeks . Split-strength training method will be applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts will be conducted by certified trainers to ensure they are performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants will be increased by 5%. In the MVT group, 3 sets of 8-12 repetitions: between sets intervals: of 120 seconds will be performed. Receives: Other: Resistance exercise-LVT |
| moderate volume (MVT) resistance training | Active comparator | 4 sessions of 12 exercises per week for 8 weeks . Split-strength training method will be applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts will be conducted by certified trainers to ensure they are performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants will be increased by 5%. In the MVT group, 3 sets of 8-12 repetitions: between sets intervals: of 120 seconds will be performed. Receives: Other: Resistance exercise-MVT |
| high volume (HVT) resistance training | Active comparator | 5 sessions of 12 exercises per week for 8 weeks . Split-strength training method will be applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts will be conducted by certified trainers to ensure they are performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants will be increased by 5%. In the MVT group, 3 sets of 8-12 repetitions: between sets intervals: of 120 seconds will be performed. Receives: Other: Resistance exercise-HVT |
What is being measured
The primary outcome is the main question the study is designed to answer.
Body height measurements
A stadiometer is attached to the wall. It has a sliding horizontal headpiece that's adjusted to rest on top of your head. The measurement of height will be conducted using a Mesilife portable stadiometer.
Measured: at baseline and end of 8 week
Anthropometric measurements
Bio-impedance body composition analysis system
Measured: at baseline and end of 8 week
Muscle thickness measurements
A portable ultrasound scanner will be used to determine muscle thickness. At one location, muscle thickness will be measured: Between the greater trochanter and the lateral epicondyle of the thigh, the thickness of the quadriceps femoris (Vastus lateralis) will be measured at 50%. Ultrasound tests will be done at the start of the study and 8 weeks later, by a researcher blinded to the interventions. All tests were performed in the morning when participants are fasting.
Measured: at baseline and end of 8 week
Countermovement Jump (CMJ)
Countermovement Jump (CMJ) values of all participants will be measured. Peak muscle power measures in watts (W) using the Accupeak power2.0 portable force platform system . The measurement frequency of the device was set to 500 Hz. Participants will undrergo a 10-minute warm-up program before completing a CMJ. Participants will be asked to begin a downward movement and jump as high as possible after hearing a tone from the computer.
Measured: at baseline and end of 8 week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Jun 2024
- Study start11 Nov 2021
- Primary completion11 Dec 2023
- Study completion11 Jan 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 15 participants (actual)
Sponsor and investigators
- Lead sponsor
- Princess Nourah Bint Abdulrahman University
- Sponsor type
- University, hospital or other
- Collaborators
- Kırıkkale University
- Responsible party
- Principal investigator, Monira Aldhahi, Princess Nourah Bint Abdulrahman University
- Investigators
- Dondu Ugurlu, Phd, Principal investigator, dondusimsek@kku.edu.tr
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06449300
- Sponsor's protocol ID
- 2021.11.07
- Status last verified
- Jun 2024
- First submitted
- 1 Jun 2024
- Last updated
- 14 Jun 2024
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Ugurlu D, Gulu M, Yapici H, Yagin FH, Comertpay E, Eroglu O, Afonso J, Aldhahi MI. Dose-response effects of 8-week resistance training on body composition and muscular performance in untrained young women: A quasi-experimental design. Medicine (Baltimore). 2024 Nov 1;103(44):e40322. doi: 10.1097/MD.0000000000040322.
PubMed 39496043
Study at a glance
From the registry record, last updated by the sponsor on 14 Jun 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Different Volumes of Resistance Training on Body Composition, Peak Power, and Muscle Thickness in Untrained Healthy Women
- ClinicalTrials.gov ID
- NCT06449300
- Acronym / sponsor ID
- 2021.11.07
- Conditions
- Healthy
- Keywords
- Strength training, muscle growth
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 15 participants (actual)
- Lead sponsor
- Princess Nourah Bint Abdulrahman UniversityUniversity, hospital or other
- Collaborators
- Kırıkkale University
- Study start
- 11 Nov 2021 (actual)
- Primary completion
- 11 Dec 2023 (actual)
- Study completion
- 11 Jan 2024 (actual)
- First posted
- 10 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study explores the effects of varying volumes of resistance training on body composition, strength, peak power, and muscle thickness in untrained women over eight weeks. A randomized controlled trial involving 45 female college students assessed the outcomes across three groups: low-volume training (LVT) with three weekly sessions, moderate-volume training (MVT) with four weekly sessions, and high-volume training (HVT) with five weekly sessions. Participants were untrained, aged 18-65, and free from cardiovascular diseases or performance-enhancing drugs.
The hypothesis suggested that moderate volume training would yield optimal muscle development, considering the potential non-linear dose-response relationship where excessive training might be detrimental. Measurements included body composition, muscle thickness, and peak power through a force platform during vertical jumps.
Data analysis focused on changes in muscle thickness, strength, and body composition, with statistical significance set at p < 0.05. The study aimed to provide insights into how different training volumes affect physiological adaptations in untrained women, potentially guiding fitness regimen optimizations for similar populations.
Detailed description
The study aimed to investigate the effect of different resistance training volume (low-, moderate, and high) on body composition, maximal strength, peak power, and muscle thickness in untrained women over eight weeks. The study is a three-arm, randomized controlled trial, 45 female college students participated, fit the specific inclusion criteria like age between 18-65 and being untrained. Exclusion criteria included the use of performance-enhancing drugs or recent resistance training.
Participants were randomly assigned to one of three groups: low-volume training (LVT) with three sessions weekly, moderate-volume training (MVT) with four sessions weekly, and high-volume training (HVT) with five sessions weekly. Each session comprised 12 exercises. Split split-strength training method was applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts were conducted by certified trainers to ensure they were performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants were increased by 5%. In the LVT group, 3 sets of 8-12 repetitions of: between sets interval: 120 seconds (3 days/wk), in the MVT group, 3 sets of 8-12 repetitions of: between sets interval: 120 seconds (4 days/wk), in the HVT group, 3 sets of 8-12 repetitions of: between sets interval: 120 seconds exercises (5 days/wk) were performed.
Results and data analysis involved anthropometric measurements, muscle thickness via ultrasound, and peak power from the vertical jump test. Statistical significance was set at p < 0.05, and effect sizes were calculated with Partial Eta Squared values.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| low volume (LVT) resistance training | Experimental | Other: Resistance exercise-LVT3 sessions of 12 exercises per week for 8 weeks . Split-strength training method will be applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts will be conducted by certified trainers to ensure they are performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants will be increased by 5%. In the MVT group, 3 sets of 8-12 repetitions: between sets intervals: of 120 seconds will be performed. |
| moderate volume (MVT) resistance training | Active comparator | Other: Resistance exercise-MVT4 sessions of 12 exercises per week for 8 weeks . Split-strength training method will be applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts will be conducted by certified trainers to ensure they are performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants will be increased by 5%. In the MVT group, 3 sets of 8-12 repetitions: between sets intervals: of 120 seconds will be performed. |
| high volume (HVT) resistance training | Active comparator | Other: Resistance exercise-HVT5 sessions of 12 exercises per week for 8 weeks . Split-strength training method will be applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts will be conducted by certified trainers to ensure they are performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants will be increased by 5%. In the MVT group, 3 sets of 8-12 repetitions: between sets intervals: of 120 seconds will be performed. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adult women between ages of 18 -65 years old
- Able to walk independently
- Free of any history of cardiovascular disease
- Untrained (less than 150 min of PA/week)
Key exclusion criteria (3 listed)
- Intake of performance-enhancing drugs, anabolic steroids
- Any history of injury, or physiological or physical limitations that could affect the ability to perform training and physical testing in the last year.
- Those who had been RT for more than 2 months in the previous 6 months were excluded.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Resistance exercise-LVT(low volume training - 3 sessions of 12 exercises per week) | Other | low volume (LVT) resistance training |
| Resistance exercise-MVT(moderate volume training - 4 sessions of 12 exercises per week) | Other | moderate volume (MVT) resistance training |
| Resistance exercise-HVT(high volume training - 5 sessions of 12 exercises per week) | Other | high volume (HVT) resistance training |
Primary outcome
Body height measurements
Time frame: at baseline and end of 8 week
A stadiometer is attached to the wall. It has a sliding horizontal headpiece that's adjusted to rest on top of your head. The measurement of height will be conducted using a Mesilife portable stadiometer.
Anthropometric measurements
Time frame: at baseline and end of 8 week
Bio-impedance body composition analysis system
Muscle thickness measurements
Time frame: at baseline and end of 8 week
A portable ultrasound scanner will be used to determine muscle thickness. At one location, muscle thickness will be measured: Between the greater trochanter and the lateral epicondyle of the thigh, the thickness of the quadriceps femoris (Vastus lateralis) will be measured at 50%. Ultrasound tests will be done at the start of the study and 8 weeks later, by a researcher blinded to the interventions. All tests were performed in the morning when participants are fasting.
Countermovement Jump (CMJ)
Time frame: at baseline and end of 8 week
Countermovement Jump (CMJ) values of all participants will be measured. Peak muscle power measures in watts (W) using the Accupeak power2.0 portable force platform system . The measurement frequency of the device was set to 500 Hz. Participants will undrergo a 10-minute warm-up program before completing a CMJ. Participants will be asked to begin a downward movement and jump as high as possible after hearing a tone from the computer.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jun 2024.
- Derived from this study: PubMed 39496043Ugurlu D, Gulu M, Yapici H, Yagin FH, Comertpay E, Eroglu O, Afonso J, Aldhahi MI. Dose-response effects of 8-week resistance training on body composition and muscular performance in untrained young women: A quasi-experimental design. Medicine (Baltimore). 2024 Nov 1;103(44):e40322. doi: 10.1097/MD.0000000000040322.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Dondu Ugurlu, Phd principal investigator
dondusimsek@kku.edu.tr
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Resistance exercise-LVT, Resistance exercise-MVT and Resistance exercise-HVT in people with Healthy, run by Princess Nourah Bint Abdulrahman University at 1 site in Saudi Arabia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 14 Jun 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Saudi Arabia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Body height measurements (time frame: at baseline and end of 8 week). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06449300, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jun 2024; AzTrials last refreshed its copy on 7 Nov 2026.