Alcohol UseNCT06457841
Stress and Resilience
A study testing Direct Interpersonal Exchange, Vicarious Interpersonal Exchange and Daily Hassles in people with Alcohol Use and Cannabis Use, run by University of Washington at 2 sites in United States.
Trial summary
Alcohol and cannabis are the most misused psychoactive substances in the United States. The proposed research examines how personally relevant stressful experiences may lead to alcohol and cannabis use. Read more about this study
- Who is it for?
- Ages 18 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Alcohol Use, Cannabis Use
- What is being tested?
- Direct Interpersonal Exchange, Vicarious Interpersonal Exchange and Daily Hassles
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 456 participants
- Where
- 2 sitesUnited States
- Study dates
- 9 May 2024to Jul 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Of Afro-descent
- Proficient in English
- Alcohol and/or cannabis use at least 2-3 times in the past month
- Endorse having used alcohol and/or cannabis to cope
Who cannot join
- Having participated in similar studies by the research team
- Obtain cut-off scores on scale items indicating possible loss of control and needing to cut down or quit alcohol and/or cannabis use
- In or seeking treatment for alcohol and/or cannabis use disorder
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
United States2 sites, 2 recruiting
- Recruiting
Southern Methodist University
Dallas, Texas, 75204
Ernest N Jouriles, Ph.D., 214-768-2360, ejourile@smu.edu
- Recruiting
University of Washington
Seattle, Washington, 98195
P. Priscilla Lui, Ph.D., 206-685-8391, pplui@uw.edu
Kevin M King, Ph.D.
About this study
Official title: Black Adult Resilience Study
Alcohol and cannabis are the most misused psychoactive substances in the United States. The proposed research examines how personally relevant stressful experiences may lead to alcohol and cannabis use. The proposed research is also designed to identify possible targets for prevention and treatment efforts to help reduce drug use.
- Conditions
- Alcohol Use, Cannabis Use
- Being tested
- Direct Interpersonal Exchange, Vicarious Interpersonal Exchange, Daily Hassles
- Medical subject headings
- Alcohol Drinking
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Direct Interpersonal ExchangeBehavioural
Simulated a negative personally relevant interpersonal experience that is received directly from a perpetrator, commonly experienced in everyday lives
Vicarious Interpersonal ExchangeBehavioural
Hearing or observing a negative personally relevant interpersonal experience that is reported by another person of the same background
Daily HasslesBehavioural
Day-to-day stressors associated with school, work, finances
| Study group | Role | What they receive |
|---|---|---|
| Direct Interpersonal Exchange | Experimental | Simulated a negative personally relevant interpersonal experience that is received directly from a perpetrator, commonly experienced in everyday lives Receives: Behavioral: Direct Interpersonal Exchange |
| Vicarious Interpersonal Exchange | Experimental | Hearing or observing a negative personally relevant interpersonal experience that is reported by another person of the same background Receives: Behavioral: Vicarious Interpersonal Exchange |
| Daily Hassles | Placebo comparator | Day-to-day stressors associated with school, work, finances Receives: Behavioral: Daily Hassles |
What is being measured
The primary outcome is the main question the study is designed to answer.
Momentary Alcohol and/or Cannabis Craving
Momentary Alcohol and Cannabis Craving Scale will be administered (adapted from the Momentary Cannabis Craving Scale; Davis et al., 2024) immediately after the intervention. Mean scores will range from 1 to 7, with higher scores indicating greater momentary craving.
Measured: Immediately after the intervention (i.e., within 1 minute)
Duration of Alcohol and Cannabis Intoxication
Self-reported number of hours of intoxication within 48 hours after the intervention
Measured: 48 Hours Post-Intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Jun 2024
- Study start9 May 2024
- Primary completionJul 2027 (estimated)
- Study completionJul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Alcohol UseStudies of the same condition, open and under way.
- More trials run by University of WashingtonThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 456 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Washington
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Responsible party
- Principal investigator, Priscilla Lui, University of Washington
- Investigators
- P. Priscilla Lui, Ph.D., Principal investigator, University of Washington
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06457841
- Sponsor's protocol ID
- STUDY00018058
- Other IDs
- R01DA058626
- Status last verified
- Jul 2025
- First submitted
- 28 May 2024
- Last updated
- 15 Jul 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Black Adult Resilience Study
- ClinicalTrials.gov ID
- NCT06457841
- Acronym / sponsor ID
- STUDY00018058
- Conditions
- Alcohol Use, Cannabis Use
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 456 participants (estimated)
- Lead sponsor
- University of WashingtonUniversity, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Study start
- 9 May 2024 (actual)
- Primary completion
- Jul 2027 (estimated)
- Study completion
- Jul 2027 (estimated)
- First posted
- 13 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Alcohol and cannabis are the most misused psychoactive substances in the United States. The proposed research examines how personally relevant stressful experiences may lead to alcohol and cannabis use. The proposed research is also designed to identify possible targets for prevention and treatment efforts to help reduce drug use.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Direct Interpersonal Exchange | Experimental | Behavioral: Direct Interpersonal ExchangeSimulated a negative personally relevant interpersonal experience that is received directly from a perpetrator, commonly experienced in everyday lives |
| Vicarious Interpersonal Exchange | Experimental | Behavioral: Vicarious Interpersonal ExchangeHearing or observing a negative personally relevant interpersonal experience that is reported by another person of the same background |
| Daily Hassles | Placebo comparator | Behavioral: Daily HasslesDay-to-day stressors associated with school, work, finances |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Of Afro-descent
- Proficient in English
- Alcohol and/or cannabis use at least 2-3 times in the past month
- Endorse having used alcohol and/or cannabis to cope
Key exclusion criteria (3 listed)
- Having participated in similar studies by the research team
- Obtain cut-off scores on scale items indicating possible loss of control and needing to cut down or quit alcohol and/or cannabis use
- In or seeking treatment for alcohol and/or cannabis use disorder
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Direct Interpersonal ExchangeSimulated a negative personally relevant interpersonal experience that is received directly from a perpetrator, commonly experienced in everyday lives | Behavioural | Direct Interpersonal Exchange |
| Vicarious Interpersonal ExchangeHearing or observing a negative personally relevant interpersonal experience that is reported by another person of the same background | Behavioural | Vicarious Interpersonal Exchange |
| Daily HasslesDay-to-day stressors associated with school, work, finances | Behavioural | Daily Hassles |
Primary outcome
Momentary Alcohol and/or Cannabis Craving
Time frame: Immediately after the intervention (i.e., within 1 minute)
Momentary Alcohol and Cannabis Craving Scale will be administered (adapted from the Momentary Cannabis Craving Scale; Davis et al., 2024) immediately after the intervention. Mean scores will range from 1 to 7, with higher scores indicating greater momentary craving.
Duration of Alcohol and Cannabis Intoxication
Time frame: 48 Hours Post-Intervention
Self-reported number of hours of intoxication within 48 hours after the intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jul 2025.
- Individual participant dataSharing planned: No
Related trials for Alcohol Use
Recruiting
The Trans-Led Care Study
Substance Abuse, Substance Addiction
RecruitingObservational study
SMART-r: Substance Monitoring and Active Relapse Tracking Repository
Alcoholism, Substance-Related Disorders
Recruiting
Momentary Coping Prompts and Hair Steroids in College Students
Emotional Regulation, Alcohol Drinking in College
RecruitingPhase 2/3
Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder
Alcohol Use Disorder, Alcohol Withdrawal
Not yet recruitingObservational study
Disease Intervention Specialist (DIS) for SUD
Substance Use Disorder (SUD), Opioid Use Disorder
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
P. Priscilla Lui, Ph.D. principal investigator
University of Washington
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Direct Interpersonal Exchange, Vicarious Interpersonal Exchange and Daily Hassles in people with Alcohol Use and Cannabis Use, run by University of Washington at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 15 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact P. Priscilla Lui, Ph.D. (206-685-8391, pplui@uw.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Momentary Alcohol and/or Cannabis Craving (time frame: Immediately after the intervention (i.e., within 1 minute)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jul 2025.