MultimorbidityPOPMIX-SmokingNCT06458205
Impact of Multi-Component Interventions on High-Risk COPD Smokers
A study testing Multi-component intervention for smokers in people with Multimorbidity and Tobacco Use Cessation, run by Peking Union Medical College at 1 site in China.
Trial summary
Study Participants: In our study, we focus on smokers who self-report a "current smoking" status or smoking cessation less than 6 months. This trial is a sub-trial of "Impact of Multi-Component Interventions on a High-Risk COPD population" (Protocol ID: CAMS\&PUMC-IEC-2024-040). Read more about this study
- Who is it for?
- Ages 35 years and older
- Conditions the study is for
- Multimorbidity, Tobacco Use Cessation, Smoking Reduction
- What is being tested?
- Multi-component intervention for smokers
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 4,247 participants
- Where
- 1 siteChina
- Study dates
- 17 Jun 2024to 31 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Aged 35 and above;
- High-risk COPD population defined by the score of COPD-SQ ≥ 16;
- Self-report currently smoking or smoking cessation less than 6 month;
- Local residents who stay within a township in the previous 3 months and plan to stay within the same township for the next 12 months.
Who cannot join
- Those who suffer from severe cognitive disorder or total loss of ability of daily living.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Population Medicine Multimorbidity Interventions in Xishui on High-risk COPD Smokers: A Cluster Randomized Controlled Trial
Study Participants: In our study, we focus on smokers who self-report a "current smoking" status or smoking cessation less than 6 months. This trial is a sub-trial of "Impact of Multi-Component Interventions on a High-Risk COPD population" (Protocol ID: CAMS\&PUMC-IEC-2024-040). All smokers in this trial are either from the high-risk COPD population (defined by COPD-SQ score≥16) .
Intervention: For study participants in the intervention arm, we will ask them to finish an online COPD-SQ questionnaire with notification of his or her COPD high risk. For those whose score of COPD-SQ ≥ 16, we will provide a face-to-face survey, simple physical examination, pulmonary function tests, and provide a multi-component intervention at baseline. For smokers in the intervention arm, we provide a digital health intervention program, NicQuit, to whom could familiarly use intelligent mobile phones, and health education for all smokers. We also provide community-based spirometry pulmonary function test (PFT) and education to smokers. If smokers whose post-bronchodilator FEV1/FVC<0.7, they will be spirometry-defined COPD patients and will be encouraged to seek treatment and medication to the superior hospitals. Additionally, we provide (1) another digital health intervention programs to smokers with mental health issues; (2) CBT-based health education for study participants with abnormal BMI; (3) active recruitment into National Essential Public Health Program in China for those with abnormal blood pressure and blood glucose. Intensive follow-ups will be conducted at month 3 (telephone interview), month 6 (face-to-face with full steps of physical examination), and month 12.
Read more
Comparison: Those who are assigned in the control arm, we will ask them to finish the same COPD-SQ online questionnaire with notification of his or her COPD high risk status and a face-to-face survey. No physical examinations, community-based pulmonary function tests will be given.
Outcomes: The primary outcomes are self-reported average number of cigarettes consumed per day, smoking dependence index, and CO measurement.
- Conditions
- Multimorbidity, Tobacco Use Cessation, Smoking Reduction
- Being tested
- Multi-component intervention for smokers
- Medical subject headings
- Tobacco Use Cessation, Smoking Reduction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Multi-component intervention for smokersCombination product
- Community-based spirometry pulmonary function tests and result interpretations and health education;
- A digital health intervention program, NicQuit, for smokers(very familiar with intelligent mobile phone);
- A digital health intervention program, EmoEase, for smokers whose WEMWBS questionnaire score is lower than 45(very familiar with intelligent mobile phone);
- Health education to smokers for smoking cessation;
- Health education to smokers with mental health issues;
- Encouragement to seek professional medication treatment in superior hospitals for spirometry-defined COPD patients or asthma patients;
- To actively include smokers whose blood pressure's higher than 140/90 mmHg or/and whose random blood glucose higher than11.1mmol/L into the National Essential Public Health Service in China;
- A CBT-based health education to the BMI abnormal, i.e., BMI > 24.0 or BMI <18.5;
- Pay-for-population mechanism for medical practitioners.
| Study group | Role | What they receive |
|---|---|---|
| Intervention arm | Experimental | For all townships within the intervention arm, we have constructed a pay-for-population mechanism to incentivize all medical practitioners to care for population health within each township. For smokers, we will provide a multi-component intervention: (1) NicQuit, a CBT-based digital health intervention for those who use intelligent mobile phones; (2) community-based pulmonary function test; (3) health education and encouragement to seek medication in superior hospitals for those spirometry-defined COPD patients; (4) CBT-based health education to the abnormal BMI; (5) health education to smoking cessation; (6) Active recruitment of smokers with high blood pressure or high blood glucose measurement. Intensive follow-ups will be at month 3, 6, and 12. Receives: Combination Product: Multi-component intervention for smokers |
| Control Arm | No intervention | We will notify smokers with high-risk COPD to seek further diagnoses in superior hospitals. We provide a face-to-face survey to smokers with high-risk COPD. No other specified interventions will be given, they will be always accessible to usual care within the study period. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Amount of smoking
Definition: Average number of cigarettes smoked per day; Variable type: Continuous; Measurement: Respondent's answer to the question.
Measured: 1 year
Smoking Dependence
Definition: A scale that measures the degree of smoking dependence; Variable type: Continuous; Measurement: Respondent's answer to the question. Introduction to Smoking Dependence Scale: Chinese version of Fagerström test for nicotine dependence (FTND), ranging from 0 to 10, the higher the score, the severer nicotine dependence will be. Also Heaviness of Smoking Index (HSI) will also be measured, ranging from 0 to 6, the higher the score, the worsen the nicotine dependence will be
Measured: 1 year
Secondary outcomes (34)
Self-rate health status
Definition: General self-assessed health status; Variable type: Continuous; Measurement: EQ-5D scale; Introduction to EQ-5D-5L scale: The 5-level EQ-5D version (EQ-5D-5L) was introduced by the EuroQol Group in 2009 to improve the instrument's sensitivity and to reduce ceiling effects, as compared to the EQ-5D-3L. The scale could be transferred to health utility value, ranging from 0 to 1 continuously. 0 represents death and 1 represents perfect health.
Measured: 1 year
Number of Chronic Conditions Controlled
Definition: Among 7 objectively measured health conditions (COPD, asthma, depression symptoms, anxiety symptoms, BMI, hypertension, type 2 diabetes), the number of chronic conditions controlled; Variable type: Counting data; Measurement: Through objective physical examination or validated scale;
Measured: 1 year
Physical proof of cigarettes
Definition: Can you show me your cigarettes? Variable type: Binary; Measurement: Self-report questions and to let respondents show to our field workers whether he or she brings cigarettes.
Measured: 1 year
FEV1 measurement
Definition: Forced Expiratory Volume in one second (FEV1); Variable type: Continuous; Measurement: Pulmonary function test, portable spirometry;
Measured: 1 year
COPD Screening
Definition: Have you ever had a pulmonary function test?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
Self-awareness of COPD
Definition: Have you ever been diagnosed with COPD?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
COPD-Knowledge
Definition: COPD Knowledge Questionnaire; Variable type: Continuous; Measurement: Respondent's answer to the questions;
Measured: 1 year
Treatment adherence
Definition: Are you currently receiving a COPD treatment plan prescribed by a doctor or other healthcare professional?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
COPD control
Definition: Has the number of acute exacerbations decreased in the past six months?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
Blood pressure
Definition: Systolic and diastolic blood pressure (mmHg); Variable type: Continuous; Measurement: Omron portable automatic blood pressure monitor;
Measured: 1 year
Blood Glucose
Definition: Reference standard for average plasma glucose concentration over a period of time; Variable type: Continuous; Measurement: Blood glucose meter;
Measured: 1 year
Waist circumference
Definition: Waist circumference (cm); Variable type: Continuous; Measurement: Soft measuring tape;
Measured: 1 year
BMI
Definition: Body mass index (BMI), weight divided by height squared (kg/m²); Variable type: Continuous; Measurement: Calculation;
Measured: 1 year
Number of Outpatient Visits
Definition: Outpatient visits and type of hospital; Variable type: Count; Measurement: Survey/insurance/outpatient data;
Measured: 1 year
Number of Inpatient Visits
Definition: Inpatient visits and type of hospital; Variable type: Count; Measurement: Survey data/insurance/inpatient data;
Measured: 1 year
Medical expenditure within a family over the past year
Definition: Healthcare-related expenditures; Variable type: Continuous; Measurement: Survey/insurance/outpatient/inpatient data;
Measured: 1 year
Depression Symptoms
Definition: Emotional disorders, including sadness, loss, and anger; Variable type: Continuous; Measurement: PHQ-9; Introduction to PHQ-9: Patient Health Questionnaire- 9 items (PHQ-9), ranging from 0 to 27, the higher the score, the severer the depression symptoms for the respondents will be.
Measured: 1 year
Anxiety Symptoms
Definition: Unpleasant state of inner turmoil; Variable type: Continuous; Measurement: GAD-7; Introduction to GAD-7: General Anxiety Disorder - 7 (GAD-7), ranging from 0 to 21, the higher the score, the severer the anxiety symptoms for the respondents will be.
Measured: 1 year
Warwick-Edinburgh Mental Well-being Scale, WEM -WBS
Definition: Reflects overall mental health problems; Variable type: Continuous; Measurement: WEMWBS; Introduction to WEMWBS: Warwick-Edinburgh Mental Well-being Scale, ranging from 14 to 70, the lower the score, the worse one's general mental health will be.
Measured: 1 year
Productivity Loss
Definition: Productivity loss due to illness or health problems; Variable type: Continuous; Measurement: Respondent's answer to the question;
Introduction to WPAI-GH : Work Productivity and Activity Impairment-General Health (v2.0) Chinese version.WPAI outcomes are expressed as impairment percentages, with higher numbers indicating greater impairment and less productivity, i.e., worse outcomes, as follows:
Questions:
- = currently employed
- = hours missed due to health problems
- = hours missed other reasons
- = hours actually worked
- = degree health affected productivity while working
- = degree health affected regular activities
Scores:
Multiply scores by 100 to express in percentages.
Percent work time missed due to health: Q2/(Q2+Q4)
Percent impairment while working due to health: Q5/10
Percent overall work impairment due to health:
Q2/(Q2+Q4)+[(1-(Q2/(Q2+Q4)))x(Q5/10)]
Percent activity impairment due to health: Q6/10
Measured: 1 year
HBP Screening
Definition: Have you ever had your blood pressure measured by a doctor, nurse, or other healthcare professional?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
HBP Diagnosis
Definition: Have you ever been diagnosed with hypertension by a doctor?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
HBP Treatment
Definition: Are you currently taking any antihypertensive medication prescribed by a doctor or other healthcare professional? ; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
HBP Control
Definition: Blood pressure within the normal range at the end-of-year follow-up; Variable type: Binary; Measurement: Blood pressure measurement;
Measured: 1 year
T2DM Screening
Definition: Have you ever had your blood glucose measured by a doctor, nurse, or other healthcare professional?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
T2DM Diagnosis
Definition: Have you ever been diagnosed with T2DM by a doctor?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
T2DM Treatment
Definition: Are you currently receiving a type 2 diabetes treatment plan prescribed by a doctor or other healthcare professional?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
T2DM Control
Definition: Blood glucose within the normal range at the end-of-year follow-up; Variable type: Binary; Measurement: Blood glucose measurement;
Measured: 1 year
Smoking Status
Definition: Do you currently smoke?; Variable type: Binary; Measurement: Respondent's answer to the question;
Measured: 1 year
Drinking Status
Definition: Frequency of alcohol consumption in the past 3 months; Variable type: Categorical; Measurement: Respondent's answer to the question;
Measured: 1 year
Sugar Consumption
Definition: Frequency of consumption of sugary foods/drinks; Variable type: Categorical; Measurement: Respondent's answer to the question;
Measured: 1 year
Salted Vegetables Consumption
Definition: Frequency of consumption of salty vegetables; Variable type: Categorical; Measurement: Respondent's answer to the question;
Measured: 1 year
Vegetable Consumption
Definition: Frequency of consumption of vegetable; Variable type: Categorical; Measurement: Respondent's answer to the question;
Measured: 1 year
Physical exercise
Definition: Frequency of physical exercise; Variable type: Categorical; Measurement: Respondent's answer to the question;
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Jun 2024
- Study start17 Jun 2024
- Primary completion31 Mar 2026
- Study completion31 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for MultimorbidityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 4,247 participants (actual)
Sponsor and investigators
- Lead sponsor
- Peking Union Medical College
- Sponsor type
- University, hospital or other
- Collaborators
- China-Japan Friendship Hospital
- Responsible party
- Principal investigator, Simiao Chen, Peking Union Medical College
- Investigators
- Simiao Chen, Ph.D., Principal investigator, Peking Union Medical College
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06458205
- Sponsor's protocol ID
- CAMS&PUMC-IEC-2024-042
- Acronym
- POPMIX-Smoking
- Status last verified
- Apr 2026
- First submitted
- 9 Jun 2024
- Last updated
- 4 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Chen S, Huang K, Zheng Z, Liu Y, Zhang S, Chen W, Tang X, Cao Z, Tang L, Tong X, Zhao J, He L, Jiao L, Wang Y, Zhao T, Luo Y, Lai Q, Lyu X, Dou R, Chen Q, Bunker A, Vollmer S, Geldsetzer P, Jamison D, Barnighausen T, Yang T, Wang C; POPMIX study investigators. Impact of the POPulation Medicine Multimorbidity Intervention in Xishui County (POPMIX) on people at high risk for COPD who smoke: protocol for the POPMIX-Smoking cluster randomised controlled trial. BMJ Open. 2026 May 6;16(5):e112179. doi: 10.1136/bmjopen-2025-112179.
PubMed 42091148
Study at a glance
From the registry record, last updated by the sponsor on 4 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Population Medicine Multimorbidity Interventions in Xishui on High-risk COPD Smokers: A Cluster Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT06458205
- Acronym / sponsor ID
- POPMIX-Smoking / CAMS&PUMC-IEC-2024-042
- Conditions
- Multimorbidity, Tobacco Use Cessation, Smoking Reduction
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 4,247 participants (actual)
- Lead sponsor
- Peking Union Medical CollegeUniversity, hospital or other
- Collaborators
- China-Japan Friendship Hospital
- Study start
- 17 Jun 2024 (actual)
- Primary completion
- 31 Mar 2026 (actual)
- Study completion
- 31 Mar 2026 (actual)
- First posted
- 13 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Study Participants: In our study, we focus on smokers who self-report a "current smoking" status or smoking cessation less than 6 months. This trial is a sub-trial of "Impact of Multi-Component Interventions on a High-Risk COPD population" (Protocol ID: CAMS\&PUMC-IEC-2024-040). All smokers in this trial are either from the high-risk COPD population (defined by COPD-SQ score≥16) .
Intervention: For study participants in the intervention arm, we will ask them to finish an online COPD-SQ questionnaire with notification of his or her COPD high risk. For those whose score of COPD-SQ ≥ 16, we will provide a face-to-face survey, simple physical examination, pulmonary function tests, and provide a multi-component intervention at baseline. For smokers in the intervention arm, we provide a digital health intervention program, NicQuit, to whom could familiarly use intelligent mobile phones, and health education for all smokers. We also provide community-based spirometry pulmonary function test (PFT) and education to smokers. If smokers whose post-bronchodilator FEV1/FVC<0.7, they will be spirometry-defined COPD patients and will be encouraged to seek treatment and medication to the superior hospitals. Additionally, we provide (1) another digital health intervention programs to smokers with mental health issues; (2) CBT-based health education for study participants with abnormal BMI; (3) active recruitment into National Essential Public Health Program in China for those with abnormal blood pressure and blood glucose. Intensive follow-ups will be conducted at month 3 (telephone interview), month 6 (face-to-face with full steps of physical examination), and month 12.
Comparison: Those who are assigned in the control arm, we will ask them to finish the same COPD-SQ online questionnaire with notification of his or her COPD high risk status and a face-to-face survey. No physical examinations, community-based pulmonary function tests will be given.
Outcomes: The primary outcomes are self-reported average number of cigarettes consumed per day, smoking dependence index, and CO measurement.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Intervention arm | Experimental | Combination Product: Multi-component intervention for smokersFor all townships within the intervention arm, we have constructed a pay-for-population mechanism to incentivize all medical practitioners to care for population health within each township. For smokers, we will provide a multi-component intervention: (1) NicQuit, a CBT-based digital health intervention for those who use intelligent mobile phones; (2) community-based pulmonary function test; (3) health education and encouragement to seek medication in superior hospitals for those spirometry-defined COPD patients; (4) CBT-based health education to the abnormal BMI; (5) health education to smoking cessation; (6) Active recruitment of smokers with high blood pressure or high blood glucose measurement. Intensive follow-ups will be at month 3, 6, and 12. |
| Control Arm | No intervention | –We will notify smokers with high-risk COPD to seek further diagnoses in superior hospitals. We provide a face-to-face survey to smokers with high-risk COPD. No other specified interventions will be given, they will be always accessible to usual care within the study period. |
Who may qualify
- Ages
- 35 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Aged 35 and above;
- High-risk COPD population defined by the score of COPD-SQ ≥ 16;
- Self-report currently smoking or smoking cessation less than 6 month;
- Local residents who stay within a township in the previous 3 months and plan to stay within the same township for the next 12 months.
Key exclusion criteria (1 listed)
- Those who suffer from severe cognitive disorder or total loss of ability of daily living.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Multi-component intervention for smokers1. Community-based spirometry pulmonary function tests and result interpretations and health education; 2. A digital health intervention program, NicQuit, for smokers(very familiar with intelligent mobile phone); 3. A digital health intervention program, EmoEase, for smokers whose WEMWBS questionnaire score is lower than 45(very familiar with intelligent mobile phone); 4. Health education to smokers for smoking cessation; 5. Health education to smokers with mental health issues; 6. Encouragement to seek professional medication treatment in superior hospitals for spirometry-defined COPD patients or asthma patients; 7. To actively include smokers whose blood pressure's higher than 140/90 mmHg or/and whose random blood glucose higher than11.1mmol/L into the National Essential Public Health Service in China; 8. A CBT-based health education to the BMI abnormal, i.e., BMI > 24.0 or BMI <18.5; 9. Pay-for-population mechanism for medical practitioners. | Combination product | Intervention arm |
Primary outcome
Amount of smoking
Time frame: 1 year
Definition: Average number of cigarettes smoked per day; Variable type: Continuous; Measurement: Respondent's answer to the question.
Smoking Dependence
Time frame: 1 year
Definition: A scale that measures the degree of smoking dependence; Variable type: Continuous; Measurement: Respondent's answer to the question. Introduction to Smoking Dependence Scale: Chinese version of Fagerström test for nicotine dependence (FTND), ranging from 0 to 10, the higher the score, the severer nicotine dependence will be. Also Heaviness of Smoking Index (HSI) will also be measured, ranging from 0 to 6, the higher the score, the worsen the nicotine dependence will be
34 secondary outcomes
Self-rate health status
Time frame: 1 year
Number of Chronic Conditions Controlled
Time frame: 1 year
Physical proof of cigarettes
Time frame: 1 year
FEV1 measurement
Time frame: 1 year
COPD Screening
Time frame: 1 year
Self-awareness of COPD
Time frame: 1 year
COPD-Knowledge
Time frame: 1 year
Treatment adherence
Time frame: 1 year
COPD control
Time frame: 1 year
Blood pressure
Time frame: 1 year
Blood Glucose
Time frame: 1 year
Waist circumference
Time frame: 1 year
BMI
Time frame: 1 year
Number of Outpatient Visits
Time frame: 1 year
Number of Inpatient Visits
Time frame: 1 year
Medical expenditure within a family over the past year
Time frame: 1 year
Depression Symptoms
Time frame: 1 year
Anxiety Symptoms
Time frame: 1 year
Warwick-Edinburgh Mental Well-being Scale, WEM -WBS
Time frame: 1 year
Productivity Loss
Time frame: 1 year
HBP Screening
Time frame: 1 year
HBP Diagnosis
Time frame: 1 year
HBP Treatment
Time frame: 1 year
HBP Control
Time frame: 1 year
T2DM Screening
Time frame: 1 year
T2DM Diagnosis
Time frame: 1 year
T2DM Treatment
Time frame: 1 year
T2DM Control
Time frame: 1 year
Smoking Status
Time frame: 1 year
Drinking Status
Time frame: 1 year
Sugar Consumption
Time frame: 1 year
Salted Vegetables Consumption
Time frame: 1 year
Vegetable Consumption
Time frame: 1 year
Physical exercise
Time frame: 1 year
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Jun 2026.
- Derived from this study: PubMed 42091148Chen S, Huang K, Zheng Z, Liu Y, Zhang S, Chen W, Tang X, Cao Z, Tang L, Tong X, Zhao J, He L, Jiao L, Wang Y, Zhao T, Luo Y, Lai Q, Lyu X, Dou R, Chen Q, Bunker A, Vollmer S, Geldsetzer P, Jamison D, Barnighausen T, Yang T, Wang C; POPMIX study investigators. Impact of the POPulation Medicine Multimorbidity Intervention in Xishui County (POPMIX) on people at high risk for COPD who smoke: protocol for the POPMIX-Smoking cluster randomised controlled trial. BMJ Open. 2026 May 6;16(5):e112179. doi: 10.1136/bmjopen-2025-112179.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Simiao Chen, Ph.D. principal investigator
Peking Union Medical College
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Multi-component intervention for smokers in people with Multimorbidity and Tobacco Use Cessation, run by Peking Union Medical College at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Amount of smoking (time frame: 1 year). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06458205, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Jun 2026.