Emotion RegulationNCT06458920
Social Facilitation of Emotion Regulation in Adolescence
A study testing Social regulation and Cognitive regulation in people with Emotion Regulation, run by University of California, Los Angeles at 1 site in United States.
Trial summary
The goal of this project is to test whether regulating emotions with help from a friend is more effective and long-lasting in adolescents than regulating alone, and to characterize age-related differences in the neural mechanisms supporting social versus cognitive emotion regulation. Read more about this study
- Who is it for?
- Ages 13 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Emotion Regulation
- What is being tested?
- Social regulation and Cognitive regulation
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteUnited States
- Study dates
- 5 Oct 2022to 1 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 to 25 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Adolescent participants must be 13-15 year of age
- Adult participants must be 20-25 years of age
- Proficient in English
Who cannot join
- Auditory, visual or cognitive impairment
- Any health conditions that are contraindicated for MRI
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
University of California, Los Angeles
Los Angeles, California, 90095
Jennifer Silvers, PhD, 3102069024, silvers@ucla.edu
Elizabeth Gaines, BA, (323) 989-2557, egaines@psych.ucla.edu
About this study
The goal of this project is to test whether regulating emotions with help from a friend is more effective and long-lasting in adolescents than regulating alone, and to characterize age-related differences in the neural mechanisms supporting social versus cognitive emotion regulation. Participants will complete a psychology experiment while undergoing fMRI scanning.
Read the detailed description
Participants will complete a novel paradigm during functional magnetic resonance imaging (fMRI) to examine whether adolescents (N = 50) and adults (N = 50) are more effective at down-regulating negative affect when a friend provides them with reinterpretations of negative stimuli (i.e. social reappraisal), as compared to when they reinterpret stimuli alone (i.e., cognitive reappraisal). Specifically, participants will look at pictures of upsetting events while undergoing fMRI scanning. For some pictures, they will be instructed to just look at the image. For other pictures, they will be told to listen to their friend's voice as their friend helps them to regulate their emotions. For other pictures, they will be told to regulate their emotions on their own. The primary comparison of interest is how participants regulate emotion on their own versus when their friend helps them.
- Conditions
- Emotion Regulation
- Being tested
- Social regulation, Cognitive regulation
- Medical subject headings
- Emotional Regulation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Social regulationBehavioural
Participants will regulate emotion with the help of a friend
Cognitive regulationBehavioural
Participants will regulate emotion on their own
| Study group | Role | What they receive |
|---|---|---|
| Social regulation | Experimental | Participants will regulate emotion with the help of a friend Receives: Behavioral: Social regulation |
| Cognitive regulation | Experimental | Participants will regulate emotion on their own Receives: Behavioral: Cognitive regulation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Negative affect
Participant's self-reported negative affect on 1-4 scale (1=not bad at all, 4=very bad) during experiment
Measured: 1 day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jun 2024
- Study start5 Oct 2022
- Primary completion1 Oct 2026 (estimated)
- Study completion1 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Emotion RegulationStudies of the same condition, open and under way.
- More trials run by University of California, Los AngelesThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Model description
- During one MRI scan, participants will spend part of the time regulating emotion on their own and part of the time regulating emotion with the help of a friend
- Masking
- None (open label)
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of California, Los Angeles
- Sponsor type
- University, hospital or other
- Collaborators
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Responsible party
- Principal investigator, Jennifer Silvers, PhD, University of California, Los Angeles
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06458920
- Sponsor's protocol ID
- 21-000929
- Other IDs
- R21HD108751
- Status last verified
- Jul 2026
- First submitted
- 7 Jun 2024
- Last updated
- 16 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Deidentified participant data including age, gender and negative affect
Study at a glance
From the registry record, last updated by the sponsor on 16 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Social Facilitation of Emotion Regulation in Adolescence
- ClinicalTrials.gov ID
- NCT06458920
- Acronym / sponsor ID
- 21-000929
- Conditions
- Emotion Regulation
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- University of California, Los AngelesUniversity, hospital or other
- Collaborators
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Study start
- 5 Oct 2022 (actual)
- Primary completion
- 1 Oct 2026 (estimated)
- Study completion
- 1 Oct 2026 (estimated)
- First posted
- 14 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this project is to test whether regulating emotions with help from a friend is more effective and long-lasting in adolescents than regulating alone, and to characterize age-related differences in the neural mechanisms supporting social versus cognitive emotion regulation. Participants will complete a psychology experiment while undergoing fMRI scanning.
Detailed description
Participants will complete a novel paradigm during functional magnetic resonance imaging (fMRI) to examine whether adolescents (N = 50) and adults (N = 50) are more effective at down-regulating negative affect when a friend provides them with reinterpretations of negative stimuli (i.e. social reappraisal), as compared to when they reinterpret stimuli alone (i.e., cognitive reappraisal). Specifically, participants will look at pictures of upsetting events while undergoing fMRI scanning. For some pictures, they will be instructed to just look at the image. For other pictures, they will be told to listen to their friend's voice as their friend helps them to regulate their emotions. For other pictures, they will be told to regulate their emotions on their own. The primary comparison of interest is how participants regulate emotion on their own versus when their friend helps them.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- During one MRI scan, participants will spend part of the time regulating emotion on their own and part of the time regulating emotion with the help of a friend
| Arm | Type | Receives |
|---|---|---|
| Social regulation | Experimental | Behavioral: Social regulationParticipants will regulate emotion with the help of a friend |
| Cognitive regulation | Experimental | Behavioral: Cognitive regulationParticipants will regulate emotion on their own |
Who may qualify
- Ages
- 13 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (3 listed)
- Adolescent participants must be 13-15 year of age
- Adult participants must be 20-25 years of age
- Proficient in English
Key exclusion criteria (2 listed)
- Auditory, visual or cognitive impairment
- Any health conditions that are contraindicated for MRI
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Social regulationParticipants will regulate emotion with the help of a friend | Behavioural | Social regulation |
| Cognitive regulationParticipants will regulate emotion on their own | Behavioural | Cognitive regulation |
Primary outcome
Negative affect
Time frame: 1 day
Participant's self-reported negative affect on 1-4 scale (1=not bad at all, 4=very bad) during experiment
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jul 2026.
- Individual participant dataSharing planned: Yes. Deidentified participant data including age, gender and negative affect
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Social regulation and Cognitive regulation in people with Emotion Regulation, run by University of California, Los Angeles at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 16 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Negative affect (time frame: 1 day). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jul 2026.