Ankle SprainsNCT06469099
Ankle Injuries, Imaging and Prevention Program Effectiveness in New Army Recruits
A study testing excercises in people with Ankle Sprains, run by University of Haifa at 1 site in Israel.
Trial summary
Infantry recruits will undergo a musculoskeletal examination to assess tendon, muscle, proprioception, agility, and joint status. Afterward, an exercise intervention program will be implemented, followed by a concluding evaluation. Read more about this study
- Who is it for?
- Ages 18 to 22 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Ankle Sprains
- What is being tested?
- excercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 786 participants
- Where
- 1 siteIsrael
- Study dates
- 15 Mar 2024to 15 Sep 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 22 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- soldiers ages 18-22
Who cannot join
- knows disease of the bones
- before orthopedic surgery
Trial locations and contacts
1 site in 1 country.
Israel1 site
The Academic college Levinsky-Wingate at the Wingate Institute
Netanya
About this study
Infantry recruits will undergo a musculoskeletal examination to assess tendon, muscle, proprioception, agility, and joint status. Afterward, an exercise intervention program will be implemented, followed by a concluding evaluation.
Read the detailed description
Purpose: To evaluate ankle injuries in new infantry recruits, including their characteristics, association with imaging and functional measures, and the effectiveness of a preventive exercise program.
Methods: 650 new male infantry soldiers aged 18-23 will be recruited to participate in the study at the beginning of their military training. At the beginning and the end of the training (after approximately six months), the soldiers will be assessed for the following: 1. Demographics (height, weight, leg length, BMI calculation), 2. Proprioception ability (Active Movement Extent Discrimination Apparatus AMEDA), 3. Dynamic balance (Y-Balance Test YBT), 4. Leg muscle strength (bilateral heel rise test), 5. Hip strength (hand-held dynamometer), 6. Ankle agility (hexagon agility hop test), 7. Ankle stability (Anterior Drawer Test, musculoskeletal ultrasound for the Anterior Talofibular Ligament), 8. Achilles tendon structure (Ultrasound tissue Characterization UTC), 9. Aerobic ability (3000 meters run, will be recorded by the fitness instructors at the training base). In addition, the soldiers will fill out a previous ankle sprains questionnaire, pre-induction physical activity questionnaire, the Cumberland Ankle Instability Tool (CAIT) for ankle perceived instability, and the Ankle Fear Avoidance Beliefs Questionnaire (ankle-FABQ).
The soldiers will perform a constructed ankle sprain prevention program for five minutes every day during the six-month length of the study. Every 1-2 weeks, the researcher will arrive at the training base to monitor ankle injuries. Those who are diagnosed with a sprain will undergo ultrasound evaluations, which will be performed every few weeks.
- Conditions
- Ankle Sprains
- Being tested
- excercises
- Keywords
- soldiers, injury, ankle, exercise
- Medical subject headings
- Ankle Injuries, Wounds and Injuries, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
excercisesOther
exercises for strength and balance
| Study group | Role | What they receive |
|---|---|---|
| research group | Experimental | active exercises for few weeks Receives: Other: excercises |
| control | No intervention | control group - no intervention, continue their routine |
What is being measured
The primary outcome is the main question the study is designed to answer.
Proprioception ability
Active Movement Extent Discrimination Apparatus AMEDA
Measured: baseline, end of intervention
balance
Y balance test
Measured: baseline, end of intervention
Leg muscle strength
bilateral heel rise test
Measured: baseline, end of intervention
Hip muscle strength
hand held dynamometer
Measured: baseline, end of intervention
Ankle agility
hexagon agility hop test
Measured: baseline, end of intervention
Ankle stability
Anterior Drawer Test, musculoskeletal ultrasound for the Anterior Talofibular Ligament
Measured: baseline, end of intervention
Achilles tendon structure
Ultrasound tissue Characterization for the percentage of fibers types
Measured: baseline, end of intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Jun 2024
- Study start15 Mar 2024
- Primary completion15 Sep 2025
- Study completion15 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ankle SprainsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- active soldiers will perform baseline examinations for the musculoskeletal system. following, an exercise intervention program will be conducted with follow-up examination at the termination of program.
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 786 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Haifa
- Sponsor type
- University, hospital or other
- Collaborators
- Zinman College of Physical Education and Sports Sciences
- Responsible party
- Principal investigator, Gali Dar, University of Haifa
- Investigators
- Gali Dar, Prof., Principal investigator, University of Haifa
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06469099
- Sponsor's protocol ID
- 231/22
- Status last verified
- Jan 2026
- First submitted
- 16 Jun 2024
- Last updated
- 26 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Ankle Injuries, Imaging and Prevention Program Effectiveness in New Army Recruits
- ClinicalTrials.gov ID
- NCT06469099
- Acronym / sponsor ID
- 231/22
- Conditions
- Ankle Sprains
- Keywords
- soldiers, injury, ankle, exercise
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 786 participants (actual)
- Lead sponsor
- University of HaifaUniversity, hospital or other
- Collaborators
- Zinman College of Physical Education and Sports Sciences
- Study start
- 15 Mar 2024 (actual)
- Primary completion
- 15 Sep 2025 (actual)
- Study completion
- 15 Sep 2025 (actual)
- First posted
- 21 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Infantry recruits will undergo a musculoskeletal examination to assess tendon, muscle, proprioception, agility, and joint status. Afterward, an exercise intervention program will be implemented, followed by a concluding evaluation.
Detailed description
Purpose: To evaluate ankle injuries in new infantry recruits, including their characteristics, association with imaging and functional measures, and the effectiveness of a preventive exercise program.
Methods: 650 new male infantry soldiers aged 18-23 will be recruited to participate in the study at the beginning of their military training. At the beginning and the end of the training (after approximately six months), the soldiers will be assessed for the following: 1. Demographics (height, weight, leg length, BMI calculation), 2. Proprioception ability (Active Movement Extent Discrimination Apparatus AMEDA), 3. Dynamic balance (Y-Balance Test YBT), 4. Leg muscle strength (bilateral heel rise test), 5. Hip strength (hand-held dynamometer), 6. Ankle agility (hexagon agility hop test), 7. Ankle stability (Anterior Drawer Test, musculoskeletal ultrasound for the Anterior Talofibular Ligament), 8. Achilles tendon structure (Ultrasound tissue Characterization UTC), 9. Aerobic ability (3000 meters run, will be recorded by the fitness instructors at the training base). In addition, the soldiers will fill out a previous ankle sprains questionnaire, pre-induction physical activity questionnaire, the Cumberland Ankle Instability Tool (CAIT) for ankle perceived instability, and the Ankle Fear Avoidance Beliefs Questionnaire (ankle-FABQ).
The soldiers will perform a constructed ankle sprain prevention program for five minutes every day during the six-month length of the study. Every 1-2 weeks, the researcher will arrive at the training base to monitor ankle injuries. Those who are diagnosed with a sprain will undergo ultrasound evaluations, which will be performed every few weeks.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- active soldiers will perform baseline examinations for the musculoskeletal system. following, an exercise intervention program will be conducted with follow-up examination at the termination of program.
| Arm | Type | Receives |
|---|---|---|
| research group | Experimental | Other: excercisesactive exercises for few weeks |
| control | No intervention | –control group - no intervention, continue their routine |
Who may qualify
- Ages
- 18 to 22 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- soldiers ages 18-22
Key exclusion criteria (2 listed)
- knows disease of the bones
- before orthopedic surgery
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| excercisesexercises for strength and balance | Other | research group |
Primary outcome
Proprioception ability
Time frame: baseline, end of intervention
Active Movement Extent Discrimination Apparatus AMEDA
balance
Time frame: baseline, end of intervention
Y balance test
Leg muscle strength
Time frame: baseline, end of intervention
bilateral heel rise test
Hip muscle strength
Time frame: baseline, end of intervention
hand held dynamometer
Ankle agility
Time frame: baseline, end of intervention
hexagon agility hop test
Ankle stability
Time frame: baseline, end of intervention
Anterior Drawer Test, musculoskeletal ultrasound for the Anterior Talofibular Ligament
Achilles tendon structure
Time frame: baseline, end of intervention
Ultrasound tissue Characterization for the percentage of fibers types
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jan 2026.
Related trials for Ankle Sprains
Recruiting
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Amateur Athletes With Chronic Ankle Instability
Ankle Sprain, Ankle Sprain Strain
Recruiting
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Chronic Ankle Instability
Ankle Sprains, Ankle Sprain Strain
Not yet recruiting
Collagen Scaffold Bioaugmentation for ATFL Repair in Chronic Ankle Instability
Chronic Ankle Instability, Ankle Sprain
Recruiting
Comparison of the Effects of Hip and Ankle Focused Progressive Exercise Training on Lower Extremity Function in Athletes With Chronic Ankle Instability
Ankle Sprains
RecruitingObservational study
Computed Tomography With Stress Maneuvers for Evaluation of Distal Tibiofibular Syndesmosis Instability (CTMETS)
Ankle Sprain
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Gali Dar, Prof. principal investigator
University of Haifa
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing excercises in people with Ankle Sprains, run by University of Haifa at 1 site in Israel.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Israel. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Proprioception ability (time frame: baseline, end of intervention). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jan 2026.