HealthyNCT06471244
Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method
A study testing Finger tapping, Median nerve stimulation and Speech processing in people with Healthy, run by Worcester Polytechnic Institute at 2 sites in Germany.
Trial summary
The goal of this clinical trial is to learn if an advanced 256 dry electrode EEG cap augmented with MEG readings and coupled with a new high-resolution fast brain modeling software gives a better EEG and MEG source localization in real time. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- Finger tapping, Median nerve stimulation and Speech processing
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 2 sitesGermany
- Study dates
- 1 Jan 2025to 1 Apr 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Age at least 18 and less than 66 years
- Normal hearing and (corrected) vision
- Able to understand and give informed consent
Who cannot join
- Cardiac pacemaker or pacemaker wires; neurostimulators; implanted pumps
- Metal in the body (rods, plates, screws, shrapnel, dentures, IUD) or metallic particles in the eye
- Surgical clips in the head or previous neurosurgery
- Any magnetic particles in the body
- Cochlear implants
- Prosthetic heart valves
Show all 13Show fewer
- History of skull injury or defects
- Significant claustrophobia; Ménière's disease
- Pregnancy, breast feeding
- Neurological or psychiatric diagnoses or medications influencing brain function
- Current substance abuse (exception: concurrent nicotine use is allowed)
- Failure to perform the behavioral tasks or psychological evaluation tests
- Prisoners
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Germany2 sites, 2 recruiting
- Recruiting
Technical University Ilmenau
Ilmenau
Jens Haueisen, PhD, +49 (0) 3677 69-2860, jens.haueisen@tu-ilmenau.de
- Recruiting
Max-Planck-Institut für Kognitions- und Neurowissenschaften [Cognitive and Neuroscience]
Leipzig
Burkhard Maess, PhD, +49 341 9940-2526, maess@cbs.mpg.de
About this study
The goal of this clinical trial is to learn if an advanced 256 dry electrode EEG cap augmented with MEG readings and coupled with a new high-resolution fast brain modeling software gives a better EEG and MEG source localization in real time. The main questions it aims to answer are:
- Does the testbed better localize brain sources for finger movement?
- Does the testbed better localize brain sources for median nerve stimulation?
- Does the testbed better localize brain sources for speech processing?
- Researchers will compare the predicted cortical locations with MEG data and known anatomical locations of the neuronal generators.
Read more
Participants will:
- Undergo Magnetic Resonance Imaging (MRI) scans for brain and head model creation
- Undergo three different EEG tests
- Undergo three different MEG tests
Read the detailed description
Magnetic Resonance Imaging (MRI) head/neck scans of 30 healthy subjects using the 7 Tesla Siemens Scanner will be performed at the Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig Germany with 0.5/0.7 mm isotropic resolution, for both T1 and T2 imaging sequences. Construction of computational head models from the MRI data using FreeSurfer and Charm segmentation software packages will be performed at Worcester Polytechnic Institute.
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German volunteers will be tapping with their right hand index finger. The corresponding neuronal generators are located in the M1INDEXFINGER/S1INDEXFINGER areas (primary motor/somatosensory cortex) at different latencies.
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). .Electrical stimuli over the median nerve at the right wrist will be delivered using brief transcutaneous pulses every 1.5 seconds. The task is to respond to each stimulus by pushing a button with the left-hand index finger. This generates EEG evoked responses in the S1HAND area (primary somatosensory cortex contralateral to the nerve stimuli), and the M1HAND area (primary motor cortex) at different latencies. The P20/N20 response peaking at about 20 ms is targeted, since at this latency its neuronal generators are well-known to be located in the posterior wall of the central sulcus in the Brodmann area 3b.
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German sentences will be played to the volunteers and the volunteers have to fulfill a semantic task. This generates EEG evoked responses in the known areas of the Primary Auditory Cortex (PAC).
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German volunteers will be tapping with their right hand index finger. The corresponding neuronal generators are located in the M1INDEXFINGER/S1INDEXFINGER areas (primary motor/somatosensory cortex) at different latencies.
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). Electrical stimuli over the median nerve at the right wrist will be delivered using brief transcutaneous pulses every 1.5 seconds. The task is to respond to each stimulus by pushing a button with the left-hand index finger. This generates MEG evoked responses in the S1HAND area (primary somatosensory cortex contralateral to the nerve stimuli), and the M1HAND area (primary motor cortex) at different latencies. The P20/N20 response peaking at about 20 ms is targeted, since at this latency its neuronal generators are well-known to be located in the posterior wall of the central sulcus in the Brodmann area 3b.
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German sentences will be played to the volunteers and the volunteers have to fulfill a semantic task. This generates EEG evoked responses in the known areas of the Primary Auditory Cortex (PAC).
The main questions it aims to answer are:
Does the proposed high-resolution testbed better localize brain sources for finger movement?
Does the proposed high-resolution testbed better localize brain sources for median nerve stimulation?
Does the proposed high-resolution testbed better localize brain sources for speech processing?
- Conditions
- Healthy
- Being tested
- Finger tapping, Median nerve stimulation, Speech processing
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Finger tappingOther
The volunteer is tapping with his/her right hand index finger.
Median nerve stimulationOther
Electrical pulses are applied at the wrist to the median nerve.
Speech processingOther
German sentences are played to the volunteers and the volunteers have to fulfill a semantic task.
| Study group | Role | What they receive |
|---|---|---|
| EEG/MEG data collection and processing with high density recording techniques | Experimental | Not described Receives: Other: Finger tapping; Other: Median nerve stimulation; Other: Speech processing |
What is being measured
The primary outcome is the main question the study is designed to answer.
MRI T1/T2 head/neck scans of 30 healthy subjects
Magnetic Resonance Imaging (MRI) head/neck scans of 30 healthy subjects using the 7 Tesla Siemens Scanner at the Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig Germany with 0.5/0.7 mm isotropic resolution, for both T1 and T2 imaging sequencies. Construction of computational head models from the MRI data using FreeSurfer and Charm segmentation software packages.
Measured: 1 year
EEG measurements of cortical activity in response to index finger tapping for 30 subjects
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German volunteers will be tapping with their right hand index finger. The corresponding neuronal generators are located in the M1INDEXFINGER/S1INDEXFINGER areas (primary motor/somatosensory cortex) at different latencies.
Measured: 1 year
EEG measurements of cortical activity in response to median nerve stimulation for 30 subjects
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). .Electrical stimuli over the median nerve at the right wrist will be delivered using brief transcutaneous pulses every 1.5 seconds. The task is to respond to each stimulus by pushing a button with the left-hand index finger. This generates EEG evoked responses in the S1HAND area (primary somatosensory cortex contralateral to the nerve stimuli), and the M1HAND area (primary motor cortex) at different latencies. The P20/N20 response peaking at about 20 ms is targeted, since at this latency its neuronal generators are well-known to be located in the posterior wall of the central sulcus in the Brodmann area 3b.
Measured: 1 year
EEG measurements of cortical activity in response to auditory signals for 30 subjects
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German sentences will be played to the volunteers and the volunteers have to fulfill a semantic task. This generates EEG evoked responses in the known areas of the Primary Auditory Cortex (PAC).
Measured: 1 year
MEG measurements of cortical activity in response to index finger tapping for 30 subjects
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German volunteers will be tapping with their right hand index finger. The corresponding neuronal generators are located in the M1INDEXFINGER/S1INDEXFINGER areas (primary motor/somatosensory cortex) at different latencies.
Measured: through study completion, an average of 1 year
MEG measurements of cortical activity in response to median nerve stimulation for 30 subjects
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). Electrical stimuli over the median nerve at the right wrist will be delivered using brief transcutaneous pulses every 1.5 seconds. The task is to respond to each stimulus by pushing a button with the left-hand index finger. This generates MEG evoked responses in the S1HAND area (primary somatosensory cortex contralateral to the nerve stimuli), and the M1HAND area (primary motor cortex) at different latencies. The P20/N20 response peaking at about 20 ms is targeted, since at this latency its neuronal generators are well-known to be located in the posterior wall of the central sulcus in the Brodmann area 3b.
Measured: through study completion, an average of 1 year
MEG measurements of cortical activity in response to auditory signals for 30 subjects
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German sentences will be played to the volunteers and the volunteers have to fulfill a semantic task. This generates EEG evoked responses in the known areas of the Primary Auditory Cortex (PAC).
Measured: through study completion, an average of 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jun 2024
- Study start1 Jan 2025
- Primary completion1 Apr 2027 (estimated)
- Study completion1 Apr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Worcester Polytechnic Institute
- Sponsor type
- University, hospital or other
- Collaborators
- Technische Universität Ilmenau, Max Planck Institute for Human Cognitive and Brain Sciences
- Responsible party
- Sponsor
- Investigators
- Sergey N Makaroff, PhD, Principal investigator, Worcester Polytechnic Institute
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06471244
- Sponsor's protocol ID
- 24-0779
- Status last verified
- May 2025
- First submitted
- 20 May 2024
- Last updated
- 28 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: It is our firm intention to share our MRI/EEG/MEG datasets and resources with the broader neuroimaging and general scientific communities. The BEM-FMM computational package(s), along with the manual(s), application examples and supporting experimental data/human models, will be made available to interested researchers and collaborators, based on the widely accessible MATLAB platform for Windows and Linux following publication. Researchers with approved access to NIH-supported Scientific Data Repositories - the National Data Archive Database will be able to access raw experimental data from this project to enable sufficient independent validation efforts and to allow for replication of the research findings. The data will be available at The National Institute of Mental Health Data Archive (NDA) in accordance with the NIH Principles and Guidelines.
Study at a glance
From the registry record, last updated by the sponsor on 28 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method
- ClinicalTrials.gov ID
- NCT06471244
- Acronym / sponsor ID
- 24-0779
- Conditions
- Healthy
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Worcester Polytechnic InstituteUniversity, hospital or other
- Collaborators
- Technische Universität Ilmenau, Max Planck Institute for Human Cognitive and Brain Sciences
- Study start
- 1 Jan 2025 (actual)
- Primary completion
- 1 Apr 2027 (estimated)
- Study completion
- 1 Apr 2027 (estimated)
- First posted
- 24 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn if an advanced 256 dry electrode EEG cap augmented with MEG readings and coupled with a new high-resolution fast brain modeling software gives a better EEG and MEG source localization in real time. The main questions it aims to answer are:
- Does the testbed better localize brain sources for finger movement?
- Does the testbed better localize brain sources for median nerve stimulation?
- Does the testbed better localize brain sources for speech processing?
- Researchers will compare the predicted cortical locations with MEG data and known anatomical locations of the neuronal generators.
Participants will:
- Undergo Magnetic Resonance Imaging (MRI) scans for brain and head model creation
- Undergo three different EEG tests
- Undergo three different MEG tests
Detailed description
Magnetic Resonance Imaging (MRI) head/neck scans of 30 healthy subjects using the 7 Tesla Siemens Scanner will be performed at the Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig Germany with 0.5/0.7 mm isotropic resolution, for both T1 and T2 imaging sequences. Construction of computational head models from the MRI data using FreeSurfer and Charm segmentation software packages will be performed at Worcester Polytechnic Institute.
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German volunteers will be tapping with their right hand index finger. The corresponding neuronal generators are located in the M1INDEXFINGER/S1INDEXFINGER areas (primary motor/somatosensory cortex) at different latencies.
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). .Electrical stimuli over the median nerve at the right wrist will be delivered using brief transcutaneous pulses every 1.5 seconds. The task is to respond to each stimulus by pushing a button with the left-hand index finger. This generates EEG evoked responses in the S1HAND area (primary somatosensory cortex contralateral to the nerve stimuli), and the M1HAND area (primary motor cortex) at different latencies. The P20/N20 response peaking at about 20 ms is targeted, since at this latency its neuronal generators are well-known to be located in the posterior wall of the central sulcus in the Brodmann area 3b.
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German sentences will be played to the volunteers and the volunteers have to fulfill a semantic task. This generates EEG evoked responses in the known areas of the Primary Auditory Cortex (PAC).
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German volunteers will be tapping with their right hand index finger. The corresponding neuronal generators are located in the M1INDEXFINGER/S1INDEXFINGER areas (primary motor/somatosensory cortex) at different latencies.
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). Electrical stimuli over the median nerve at the right wrist will be delivered using brief transcutaneous pulses every 1.5 seconds. The task is to respond to each stimulus by pushing a button with the left-hand index finger. This generates MEG evoked responses in the S1HAND area (primary somatosensory cortex contralateral to the nerve stimuli), and the M1HAND area (primary motor cortex) at different latencies. The P20/N20 response peaking at about 20 ms is targeted, since at this latency its neuronal generators are well-known to be located in the posterior wall of the central sulcus in the Brodmann area 3b.
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German sentences will be played to the volunteers and the volunteers have to fulfill a semantic task. This generates EEG evoked responses in the known areas of the Primary Auditory Cortex (PAC).
The main questions it aims to answer are:
Does the proposed high-resolution testbed better localize brain sources for finger movement?
Does the proposed high-resolution testbed better localize brain sources for median nerve stimulation?
Does the proposed high-resolution testbed better localize brain sources for speech processing?
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| EEG/MEG data collection and processing with high density recording techniques | Experimental | Other: Finger tapping, Other: Median nerve stimulation, Other: Speech processing |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Age at least 18 and less than 66 years
- Normal hearing and (corrected) vision
- Able to understand and give informed consent
Key exclusion criteria (13 listed)
- Cardiac pacemaker or pacemaker wires; neurostimulators; implanted pumps
- Metal in the body (rods, plates, screws, shrapnel, dentures, IUD) or metallic particles in the eye
- Surgical clips in the head or previous neurosurgery
- Any magnetic particles in the body
- Cochlear implants
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Finger tappingThe volunteer is tapping with his/her right hand index finger. | Other | EEG/MEG data collection and processing with high density recording techniques |
| Median nerve stimulationElectrical pulses are applied at the wrist to the median nerve. | Other | EEG/MEG data collection and processing with high density recording techniques |
| Speech processingGerman sentences are played to the volunteers and the volunteers have to fulfill a semantic task. | Other | EEG/MEG data collection and processing with high density recording techniques |
Primary outcome
MRI T1/T2 head/neck scans of 30 healthy subjects
Time frame: 1 year
Magnetic Resonance Imaging (MRI) head/neck scans of 30 healthy subjects using the 7 Tesla Siemens Scanner at the Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig Germany with 0.5/0.7 mm isotropic resolution, for both T1 and T2 imaging sequencies. Construction of computational head models from the MRI data using FreeSurfer and Charm segmentation software packages.
EEG measurements of cortical activity in response to index finger tapping for 30 subjects
Time frame: 1 year
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German volunteers will be tapping with their right hand index finger. The corresponding neuronal generators are located in the M1INDEXFINGER/S1INDEXFINGER areas (primary motor/somatosensory cortex) at different latencies.
EEG measurements of cortical activity in response to median nerve stimulation for 30 subjects
Time frame: 1 year
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). .Electrical stimuli over the median nerve at the right wrist will be delivered using brief transcutaneous pulses every 1.5 seconds. The task is to respond to each stimulus by pushing a button with the left-hand index finger. This generates EEG evoked responses in the S1HAND area (primary somatosensory cortex contralateral to the nerve stimuli), and the M1HAND area (primary motor cortex) at different latencies. The P20/N20 response peaking at about 20 ms is targeted, since at this latency its neuronal generators are well-known to be located in the posterior wall of the central sulcus in the Brodmann area 3b.
EEG measurements of cortical activity in response to auditory signals for 30 subjects
Time frame: 1 year
On-skin voltage recordings will be done with 256 dry electrodes. Our EEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German sentences will be played to the volunteers and the volunteers have to fulfill a semantic task. This generates EEG evoked responses in the known areas of the Primary Auditory Cortex (PAC).
MEG measurements of cortical activity in response to index finger tapping for 30 subjects
Time frame: through study completion, an average of 1 year
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German volunteers will be tapping with their right hand index finger. The corresponding neuronal generators are located in the M1INDEXFINGER/S1INDEXFINGER areas (primary motor/somatosensory cortex) at different latencies.
MEG measurements of cortical activity in response to median nerve stimulation for 30 subjects
Time frame: through study completion, an average of 1 year
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). Electrical stimuli over the median nerve at the right wrist will be delivered using brief transcutaneous pulses every 1.5 seconds. The task is to respond to each stimulus by pushing a button with the left-hand index finger. This generates MEG evoked responses in the S1HAND area (primary somatosensory cortex contralateral to the nerve stimuli), and the M1HAND area (primary motor cortex) at different latencies. The P20/N20 response peaking at about 20 ms is targeted, since at this latency its neuronal generators are well-known to be located in the posterior wall of the central sulcus in the Brodmann area 3b.
MEG measurements of cortical activity in response to auditory signals for 30 subjects
Time frame: through study completion, an average of 1 year
On-skin voltage recordings will be done with 256 dry electrodes. Our MEG protocols will collect 240 trials per subject (3 runs of 80 trials each). German sentences will be played to the volunteers and the volunteers have to fulfill a semantic task. This generates EEG evoked responses in the known areas of the Primary Auditory Cortex (PAC).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 May 2025.
- Individual participant dataSharing planned: Yes. It is our firm intention to share our MRI/EEG/MEG datasets and resources with the broader neuroimaging and general scientific communities. The BEM-FMM computational package(s), along with the manual(s), application examples and supporting experimental data/human models, will be made available to interested researchers and collaborators, based on the widely accessible MATLAB platform for Windows and Linux following publication. Researchers with approved access to NIH-supported Scientific Data Repositories - the National Data Archive Database will be able to access raw experimental data from this project to enable sufficient independent validation efforts and to allow for replication of the research findings. The data will be available at The National Institute of Mental Health Data Archive (NDA) in accordance with the NIH Principles and Guidelines.
Related trials for Healthy
Recruiting
THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS
Physical Activity, Body Image
Not yet recruitingPhase 1
A Phase I Study of GLR2053 Tablets in Chinese Healthy Adult Participants
Atopic Dermatitis
Recruiting
Colon-delivered Riboflavin and Gut Microbiota Composition
Microbiome Dysbiosis, Gut Health
Not yet recruiting
Neuroergonomic Analysis of a Brain-Computer Interface Device (BCI)
Healthy Volunteers - Male and Female
RecruitingPhase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Healthy Volunteer, Atopic Dermatitis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sergey N Makaroff, PhD principal investigator
Worcester Polytechnic Institute
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Finger tapping, Median nerve stimulation and Speech processing in people with Healthy, run by Worcester Polytechnic Institute at 2 sites in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sergey N Makaroff, PhD (508-831-5017, snmakaroff@wpi.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
MRI T1/T2 head/neck scans of 30 healthy subjects (time frame: 1 year). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 May 2025.