Breathing ExercisesNCT06472167
Breathing Exercises on Lung Function
A study testing Breathing exercises in people with Breathing Exercises, run by Mansoura University Hospital at 1 site in Egypt.
Trial summary
aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test. Improve dyspnea level as assessed by Medical Research Council (MRC) dyspnea scale. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Breathing Exercises
- What is being tested?
- Breathing exercises
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jun 2024to 10 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- The patients fulfilled the criteria for COPD: the presence of a post bronchodilator FEV1 < 80% predicated together with an FEV1/FVC <0.70confirm the presence of airflow limitation that is not fully reversible.
- COPD patients ranging from mild to severe according to GOLD [stages I-IV].
- Asthmatic patients receive medical treatment for at least 6 months; and clinically stable (i.e., no exacerbation or changes in medication for ≥30 days).
- None of the individuals had been engaged in any exercise-training program before participating in the study.
- Optimized medical therapy according to GOLD \& Global Initiative for Asthma (GINA)
- Clinically stable COPD and asthmatic patients (not suffering from a recent respiratory tract infection).
- All patients are Ex-smoker
Who cannot join
- Age <18 years.
- Pregnancy
- Current Smokers
- Patients that are incapable of exercising; unable to understand any questionnaire
- Multiple co- morbidity (e.g., cardiovascular diseases, active cancer)
- Neuromuscular disease as Myasthenia gravis, kypho-scoliosis
- Diaphragmatic Paralysis (paralyzed diaphragm exhibiting abnormal paradoxical movement, i.e., moving in a cranial direction during inspiration).
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Impact of Breathing Exercises on Lung Function in Chronic Airway Diseases
aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test. Improve dyspnea level as assessed by Medical Research Council (MRC) dyspnea scale. Improve pulmonary function tests and arterial blood gas.
Read the detailed description
Breathing exercises offer numerous benefits for individuals with chronic airway diseases, such as chronic obstructive pulmonary disease (COPD), asthma and bronchiectasis. These exercises help improve respiratory function, reduce symptoms, and enhance the overall quality of life.Techniques such as diaphragmatic breathing, incentive spirometer and pursed lip breathing help patients use their lungs more effectively. Breathing exercises can enhance lung function by increasing the efficiency of the respiratory muscles and improving ventilation. Asthma is a chronic inflammatory disorder of the airways classified as intermittent or persistent (mild, moderate or severe), according to the presence of diurnal and nocturnal symptoms, necessity of medication, frequency of exacerbation, physical activity limitations and pulmonary function. All of these symptoms deteriorate in the patient's quality of life and psychological well-being and restrict daily living physical activities (DLPA). Asthma symptoms experienced during daily living physical activities (DLPA) or the fear of triggering symptoms may keep asthmatic subjects from engaging in physical exercise, and the patients tend to be less physically active and less conditioned than healthy individuals. In addition, asthmatic patients have higher levels of anxiety and depression that have been shown to be associated with an increased number of exacerbations and the diagnosis of severe asthma. These psychosocial disorders can modify the respiratory breathing pattern, which leads to irregular breathing, frequent sighing, and predominant thoracic breathing. These irregular breathing patterns increase the number of respiratory (breathlessness, chest tightness and pain) and non-respiratory symptoms (anxiety, dizziness and fatigue). Recent Global Initiative for Chronic Obstructive Pulmonary Disease guidelines (GOLD) underline the importance of pulmonary rehabilitation (PR) as a part of an integrative multidisciplinary approach regardless of the stage of disease
- Conditions
- Breathing Exercises
- Being tested
- Breathing exercises
- Keywords
- Breathing exercises, lung function, Chronic airway diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Breathing exercisesBehavioural
Also called Diaphragmatic Breathing exercise, Pursued lip breathing
Breathing exercises as diaphragmatic breathing exercises and pursued lip breathing and incentive spirometry
| Study group | Role | What they receive |
|---|---|---|
| Chronic airway diseases treated by medication | No intervention | Chronic airway diseases treated by medication without breathing exercises |
| Chronic airway diseases treated by medication with breathing exercises | Active comparator | Chronic airway diseases treated by medication and breathing exercises Receives: Behavioral: Breathing exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
Impact of breathing exercises on Forced expiratory volume on first second (FEV1) in liter
Effect of Breathing exercises on lung function using spirometry
Measured: 6 months
Impact of breathing exercises on Forced vital capacity (FVC) in liter
Effect of Breathing exercises on lung function using spirometry
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Jun 2024
- Study start1 Jun 2024
- Primary completion10 Aug 2025
- Study completion10 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Breathing ExercisesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 100 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mansoura University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohamed Abd Elmoniem Mohamed, Mansoura University Hospital
- Investigators
- Mohamed AbdElmoniem, Principal investigator, Lecturer of chest medicine faculty of medicine Mansoura university
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06472167
- Sponsor's protocol ID
- R.24.05.2638
- Status last verified
- Aug 2026
- First submitted
- 13 Jun 2024
- Last updated
- 18 Aug 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Breathing Exercises on Lung Function in Chronic Airway Diseases
- ClinicalTrials.gov ID
- NCT06472167
- Acronym / sponsor ID
- R.24.05.2638
- Conditions
- Breathing Exercises
- Keywords
- Breathing exercises, lung function, Chronic airway diseases
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 100 participants (actual)
- Lead sponsor
- Mansoura University HospitalUniversity, hospital or other
- Study start
- 1 Jun 2024 (actual)
- Primary completion
- 10 Aug 2025 (actual)
- Study completion
- 10 Dec 2025 (actual)
- First posted
- 25 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test. Improve dyspnea level as assessed by Medical Research Council (MRC) dyspnea scale. Improve pulmonary function tests and arterial blood gas.
Detailed description
Breathing exercises offer numerous benefits for individuals with chronic airway diseases, such as chronic obstructive pulmonary disease (COPD), asthma and bronchiectasis. These exercises help improve respiratory function, reduce symptoms, and enhance the overall quality of life.Techniques such as diaphragmatic breathing, incentive spirometer and pursed lip breathing help patients use their lungs more effectively. Breathing exercises can enhance lung function by increasing the efficiency of the respiratory muscles and improving ventilation. Asthma is a chronic inflammatory disorder of the airways classified as intermittent or persistent (mild, moderate or severe), according to the presence of diurnal and nocturnal symptoms, necessity of medication, frequency of exacerbation, physical activity limitations and pulmonary function. All of these symptoms deteriorate in the patient's quality of life and psychological well-being and restrict daily living physical activities (DLPA). Asthma symptoms experienced during daily living physical activities (DLPA) or the fear of triggering symptoms may keep asthmatic subjects from engaging in physical exercise, and the patients tend to be less physically active and less conditioned than healthy individuals. In addition, asthmatic patients have higher levels of anxiety and depression that have been shown to be associated with an increased number of exacerbations and the diagnosis of severe asthma. These psychosocial disorders can modify the respiratory breathing pattern, which leads to irregular breathing, frequent sighing, and predominant thoracic breathing. These irregular breathing patterns increase the number of respiratory (breathlessness, chest tightness and pain) and non-respiratory symptoms (anxiety, dizziness and fatigue). Recent Global Initiative for Chronic Obstructive Pulmonary Disease guidelines (GOLD) underline the importance of pulmonary rehabilitation (PR) as a part of an integrative multidisciplinary approach regardless of the stage of disease
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Chronic airway diseases treated by medication | No intervention | –Chronic airway diseases treated by medication without breathing exercises |
| Chronic airway diseases treated by medication with breathing exercises | Active comparator | Behavioral: Breathing exercisesChronic airway diseases treated by medication and breathing exercises |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (7 listed)
- The patients fulfilled the criteria for COPD: the presence of a post bronchodilator FEV1 < 80% predicated together with an FEV1/FVC <0.70confirm the presence of airflow limitation that is not fully reversible.
- COPD patients ranging from mild to severe according to GOLD [stages I-IV].
- Asthmatic patients receive medical treatment for at least 6 months; and clinically stable (i.e., no exacerbation or changes in medication for ≥30 days).
- None of the individuals had been engaged in any exercise-training program before participating in the study.
- Optimized medical therapy according to GOLD \& Global Initiative for Asthma (GINA)
Key exclusion criteria (7 listed)
- Age <18 years.
- Pregnancy
- Current Smokers
- Patients that are incapable of exercising; unable to understand any questionnaire
- Multiple co- morbidity (e.g., cardiovascular diseases, active cancer)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Breathing exercisesAlso: Diaphragmatic Breathing exercise, Pursued lip breathingBreathing exercises as diaphragmatic breathing exercises and pursued lip breathing and incentive spirometry | Behavioural | Chronic airway diseases treated by medication with breathing exercises |
Primary outcome
Impact of breathing exercises on Forced expiratory volume on first second (FEV1) in liter
Time frame: 6 months
Effect of Breathing exercises on lung function using spirometry
Impact of breathing exercises on Forced vital capacity (FVC) in liter
Time frame: 6 months
Effect of Breathing exercises on lung function using spirometry
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Mohamed AbdElmoniem principal investigator
Lecturer of chest medicine faculty of medicine Mansoura university
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Breathing exercises in people with Breathing Exercises, run by Mansoura University Hospital at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Impact of breathing exercises on Forced expiratory volume on first second (FEV1) in liter (time frame: 6 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Aug 2026.