CognitionNCT06472960
Relationships Between Physical Activity and Inhibitory Control Among College Students
A study testing Moderate-intensity cycling, Vigorous-intensity cycling and Uninterrupted sitting in people with Cognition, run by Shenzhen University at 1 site in China.
Trial summary
The primary aim of this study is to explore the impact of a 20-minute aerobic exercise on inhibitory control, microvascular diameters, and brain function. The main questions it aims to answer are: 1. Read more about this study
- Who is it for?
- Ages 18 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Cognition
- What is being tested?
- Moderate-intensity cycling, Vigorous-intensity cycling and Uninterrupted sitting
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 120 participants
- Where
- 1 siteChina
- Study dates
- 1 Jul 2024to 1 Feb 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- right-handed (how was handedness assessed; i.e., "What hand do you write with?") with normal or corrected-to-normal vision and normal color vision
Who cannot join
- reported a history of cardiovascular, metabolic, gastrointestinal, neurological, or psychiatric disorders, medical conditions requiring medical care, substance addiction, strict diets (e.g., low- carbohydrate and Mediterranean diet), pregnancy, or lactation.
Trial locations and contacts
1 site in 1 country.
China1 site
Body-Brain-Mind Laboratory, School of Psychology, Shenzhen University
Shenzhen, Guangdong
Liye Zou, Dr., 18823437684, liyezou123@gmail.com
About this study
Official title: Relationships Between Physical Activity and Inhibitory Control Among College Students: fNIRS and Fundus Imaging
The primary aim of this study is to explore the impact of a 20-minute aerobic exercise on inhibitory control, microvascular diameters, and brain function. The main questions it aims to answer are:
- Is there a correlation among the level of physical activity, performance in inhibitory control, and the diameter of retinal microvasculature, and do retinal microcirculation parameters mediate this relationship?
- Does short-term aerobic exercise (moderate and high intensity) improve inhibitory control and physiological markers, such as retinal diameter and frontal brain activation, compared to a sedentary control group?
- Conditions
- Cognition
- Being tested
- Moderate-intensity cycling, Vigorous-intensity cycling, Uninterrupted sitting
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Moderate-intensity cyclingBehavioural
Moderate-intensity cycling on Ergoline Ergoselect 100
Vigorous-intensity cyclingBehavioural
Vigorous-intensity cycling on Ergoline Ergoselect 100
Uninterrupted sittingBehavioural
Uninterrupted sitting in a quiet room
| Study group | Role | What they receive |
|---|---|---|
| Moderate-intensity cycling | Experimental | Moderate-intensity cycling on Ergoline Ergoselect 100 Receives: Behavioral: Moderate-intensity cycling; Behavioral: Uninterrupted sitting |
| Vigorous-intensity cycling | Experimental | Vigorous-intensity cycling on Ergoline Ergoselect 100 Receives: Behavioral: Vigorous-intensity cycling; Behavioral: Uninterrupted sitting |
| Uninterrupted sitting | Experimental | Uninterrupted sitting in a quiet room Receives: Behavioral: Uninterrupted sitting |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cognitive function
This primary outcome measure is assessed by the modified dual-task Stroop paradigm.
Measured: 21 weeks
Retinal Vessel Diameter
Retinal Vessel Diameter is assessed by the fully automated fundus camera.
Measured: 21 weeks
Brain Connectivity
Brain connectivity is assessed by the NIRSport2 device
Measured: 21 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Jun 2024
- Study start1 Jul 2024 (estimated)
- Primary completion1 Jan 2025 (estimated)
- Study completion1 Feb 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CognitionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Shenzhen University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Liye Zou, Shenzhen University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06472960
- Sponsor's protocol ID
- SZUPaIntervention
- Status last verified
- Jun 2024
- First submitted
- 19 Jun 2024
- Last updated
- 25 Jun 2024
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Jun 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Relationships Between Physical Activity and Inhibitory Control Among College Students: fNIRS and Fundus Imaging
- ClinicalTrials.gov ID
- NCT06472960
- Acronym / sponsor ID
- SZUPaIntervention
- Conditions
- Cognition
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- Shenzhen UniversityUniversity, hospital or other
- Study start
- 1 Jul 2024 (estimated)
- Primary completion
- 1 Jan 2025 (estimated)
- Study completion
- 1 Feb 2025 (estimated)
- First posted
- 25 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The primary aim of this study is to explore the impact of a 20-minute aerobic exercise on inhibitory control, microvascular diameters, and brain function. The main questions it aims to answer are:
- Is there a correlation among the level of physical activity, performance in inhibitory control, and the diameter of retinal microvasculature, and do retinal microcirculation parameters mediate this relationship?
- Does short-term aerobic exercise (moderate and high intensity) improve inhibitory control and physiological markers, such as retinal diameter and frontal brain activation, compared to a sedentary control group?
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Moderate-intensity cycling | Experimental | Behavioral: Moderate-intensity cycling, Behavioral: Uninterrupted sittingModerate-intensity cycling on Ergoline Ergoselect 100 |
| Vigorous-intensity cycling | Experimental | Behavioral: Vigorous-intensity cycling, Behavioral: Uninterrupted sittingVigorous-intensity cycling on Ergoline Ergoselect 100 |
| Uninterrupted sitting | Experimental | Behavioral: Uninterrupted sittingUninterrupted sitting in a quiet room |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- right-handed (how was handedness assessed; i.e., "What hand do you write with?") with normal or corrected-to-normal vision and normal color vision
Key exclusion criteria (1 listed)
- reported a history of cardiovascular, metabolic, gastrointestinal, neurological, or psychiatric disorders, medical conditions requiring medical care, substance addiction, strict diets (e.g., low- carbohydrate and Mediterranean diet), pregnancy, or lactation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Moderate-intensity cyclingModerate-intensity cycling on Ergoline Ergoselect 100 | Behavioural | Moderate-intensity cycling |
| Vigorous-intensity cyclingVigorous-intensity cycling on Ergoline Ergoselect 100 | Behavioural | Vigorous-intensity cycling |
| Uninterrupted sittingUninterrupted sitting in a quiet room | Behavioural | Moderate-intensity cycling, Uninterrupted sitting, Vigorous-intensity cycling |
Primary outcome
Cognitive function
Time frame: 21 weeks
This primary outcome measure is assessed by the modified dual-task Stroop paradigm.
Retinal Vessel Diameter
Time frame: 21 weeks
Retinal Vessel Diameter is assessed by the fully automated fundus camera.
Brain Connectivity
Time frame: 21 weeks
Brain connectivity is assessed by the NIRSport2 device
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jun 2024.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Moderate-intensity cycling, Vigorous-intensity cycling and Uninterrupted sitting in people with Cognition, run by Shenzhen University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 25 Jun 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Liye Zou, Dr. (18823437684, liyezou123@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cognitive function (time frame: 21 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jun 2024.