HealthyStrength-LipNCT06480747
Strength Training and Muscle Lipids
A study testing Resistance exercise training in people with Healthy, run by University of Kansas Medical Center at 4 sites in United States.
Trial summary
The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength and power, motor unit activation, and lipid profiles of the vastus lateralis. Read more about this study
- Who is it for?
- Ages 8 to 10 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- Resistance exercise training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 14 participants
- Where
- 4 sitesUnited States
- Study dates
- 1 Jul 2024to 7 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 8 to 10 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- Healthy volunteer males and females ages 8 - 10 years.
Who cannot join
- No history or ongoing neuromuscular diseases.
- No history or ongoing musculoskeletal injuries.
- No history or ongoing disease that effects metabolism.
Trial locations and contacts
4 sites in 1 country.
United States4 sites
Hoglund Biomedical Imaging Center
Kansas City, Kansas, 66103
Neuromechanics Laboratory
Lawrence, Kansas, 66045
Exercise and Human Performance Laboratory
Overland Park, Kansas, 66213
Metabolic and Body Composition Laboratory
Overland Park, Kansas, 66213
About this study
Official title: The Effects of Strength Training on Neuromuscular Function and Muscle Lipids.
The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength and power, motor unit activation, and lipid profiles of the vastus lateralis.
- Conditions
- Healthy
- Being tested
- Resistance exercise training
- Keywords
- exercise, muscle cross-sectional area, intramyocellular lipids, extramyocellular lipids, muscle power, motor unit
- Medical subject headings
- Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Resistance exercise trainingOther
Participants will strength train via linear periodization resistance exercise training.
| Study group | Role | What they receive |
|---|---|---|
| Resistance exercise training | Experimental | Not described Receives: Other: Resistance exercise training |
| Control | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in muscular power of the leg extensors, as measured with isokinetic strength testing.
The score will reflect the muscular power of the leg extensors. The higher score, reflects greater muscular strength.
Measured: Baseline, following the intervention (9 weeks)
Secondary outcomes (1)
Change from baseline in thigh muscle cross-sectional area
Scores are measured cross-sectional area from ultrasound images. The higher score, reflects greater muscle size of the leg extensors.
Measured: Baseline, following the intervention (9 weeks)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Jun 2024
- Study start1 Jul 2024
- Primary completion7 Dec 2024
- Study completion7 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 14 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Kansas Medical Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Strength and Conditioning Association
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06480747
- Sponsor's protocol ID
- STUDY00160469
- Acronym
- Strength-Lip
- Status last verified
- Aug 2025
- First submitted
- 24 Jun 2024
- Last updated
- 20 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Strength Training on Neuromuscular Function and Muscle Lipids.
- ClinicalTrials.gov ID
- NCT06480747
- Acronym / sponsor ID
- Strength-Lip / STUDY00160469
- Conditions
- Healthy
- Keywords
- exercise, muscle cross-sectional area, intramyocellular lipids, extramyocellular lipids, muscle power, motor unit
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 14 participants (actual)
- Lead sponsor
- University of Kansas Medical CenterUniversity, hospital or other
- Collaborators
- National Strength and Conditioning Association
- Study start
- 1 Jul 2024 (actual)
- Primary completion
- 7 Dec 2024 (actual)
- Study completion
- 7 Dec 2024 (actual)
- First posted
- 28 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength and power, motor unit activation, and lipid profiles of the vastus lateralis.
Study design
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Resistance exercise training | Experimental | Other: Resistance exercise training |
| Control | No intervention | – |
Who may qualify
- Ages
- 8 to 10 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (1 listed)
- Healthy volunteer males and females ages 8 - 10 years.
Key exclusion criteria (3 listed)
- No history or ongoing neuromuscular diseases.
- No history or ongoing musculoskeletal injuries.
- No history or ongoing disease that effects metabolism.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Resistance exercise trainingParticipants will strength train via linear periodization resistance exercise training. | Other | Resistance exercise training |
Primary outcome
Change in muscular power of the leg extensors, as measured with isokinetic strength testing.
Time frame: Baseline, following the intervention (9 weeks)
The score will reflect the muscular power of the leg extensors. The higher score, reflects greater muscular strength.
1 secondary outcome
Change from baseline in thigh muscle cross-sectional area
Time frame: Baseline, following the intervention (9 weeks)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Aug 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
4 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Resistance exercise training in people with Healthy, run by University of Kansas Medical Center at 4 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 4 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in muscular power of the leg extensors, as measured with isokinetic strength testing. (time frame: Baseline, following the intervention (9 weeks)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Aug 2025.