Salivary pHNCT06504706
Effect of Matcha Tea Versus Green Tea on Salivary pH and Flow Rate in High Caries Risk Patients
A study testing Matcha Tea and Green Tea in people with Salivary pH, run by Cairo University at 1 site in Egypt.
Trial summary
Objectives: To evaluate the effect of green tea versus matcha tea on the salivary pH in high caries risk patients. Materials and methods: Total number of high caries risk patients were randomized into two equal groups (n=). Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Salivary pH
- What is being tested?
- Matcha Tea and Green Tea
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 24 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2024to 1 Jul 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- -
- 1. High caries risk patients
- Satisfactory cooperative behavior
- Age between 20-45 years old
- Males or females
- Subjects who signed informed consent
Who cannot join
- 1. Systemic diseases 2. Drug consumption during 3 past months 3. Salivary gland disorders 4. History of radiotherapy 5. Smoking
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Matcha Tea Versus Green Tea on Salivary pH and Flow Rate in High Caries Risk Patients: A Randomized Controlled Trial
Objectives: To evaluate the effect of green tea versus matcha tea on the salivary pH in high caries risk patients. Materials and methods: Total number of high caries risk patients were randomized into two equal groups (n=). Group 1 (intervention group) was given Matcha Tea and Group 2 (control group) was given green tea. A portable digital pH meter was used to measure the salivary pH at baseline and after consumption tea immediately, after 5 mins and after 10 mins.
Read the detailed description
Study Settings:
The study will be carried out at the Conservative Dentistry Department, Faculty of Dentistry, Cairo University in Egypt. Ethical approval will be taken from the Research Ethics Committee of the faculty of Dentistry, Cairo University. Signed informed consent will be signed each participant.
Recruitment:
Participants will be recruited from the patients' flow at the clinics of the Conservative Dentistry Department of Faculty of Dentistry, Cairo university.
Materials:
The Commercially available green tea and matcha tea for this study will be Lipton Tea. For preparation of green tea, 2 gr of green tea will be poured into 150 mL boiling water (100°C), after 3 minutes, it will be ready for drinking. As well as for matcha tea, 3 gr of green tea will be poured into 150 mL hot water (70°C), after 3 minutes, it will be ready drinking(7) .
Methods:
On the study day, all subjects will be instructed to brush their teeth 45 minutes after eating breakfast. Between 9-11 a.m., saliva samples will be collected through spitting method, one hour after breakfast and 15 minutes after brushing(7)
. For making the subjects blind to which tea they are drinking, the prepared tea will be served in the dark glasses. After drinking the green tea and matcha tea, every subject will be asked to bend his head forward and spit his saliva into laboratory tube every 60 seconds for 2-5 minutes. Samples will be collected immediately and 5 minutes after drinking tea(7)
.
.
Aim of the study:
The aim of this study is to evaluate the effect of green tea versus matcha tea on the salivary pH in high caries risk patients.
Research question:
In high caries risk patients, will matcha tea have the same effect as green tea on salivary pH?
PICOTS:
P: High caries risk patients I: Matcha tea C: Green tea O: Salivary pH T: T1: baseline T2: immediately T3: 5 mins T4: 10 mins
- Conditions
- Salivary pH
- Being tested
- Matcha Tea, Green Tea
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Matcha TeaProcedure or surgery
Japanese tea rich in antioxidants and Catechins
Green TeaProcedure or surgery
Green tea rich in catechins
| Study group | Role | What they receive |
|---|---|---|
| Green Tea | Active comparator | Green tea contains a significant amount of catechins, which are subgroup of flavonoids and play a vital role in maintaining health having strong bactericidal as well as antibacterial activity Receives: Procedure: Green Tea |
| Matcha Tea | Experimental | Matcha, powder of specially cultivated tea leaves, is gaining popularity in functional food and other food markets all over the world. Various studies have reported the difference in bioactive compounds in matcha as compared to green tea and other tea formulations Receives: Procedure: Matcha Tea |
What is being measured
The primary outcome is the main question the study is designed to answer.
salivary pH
pH of saliva to be measured
Measured: baseline before administration of tea, immediately after administration of tea, 5 minutes after administration of tea and 10 minutes after administration of tea
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jul 2024
- Study start1 Jan 2024
- Primary completion1 Jul 2024
- Study completion1 Jul 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Salivary pHStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomized Controlled Trial
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 24 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hadier Mahmoud Ahmed Gad, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06504706
- Sponsor's protocol ID
- 28923
- Status last verified
- Jul 2024
- First submitted
- 10 Jul 2024
- Last updated
- 17 Jul 2024
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Jul 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Matcha Tea Versus Green Tea on Salivary pH and Flow Rate in High Caries Risk Patients: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT06504706
- Acronym / sponsor ID
- 28923
- Conditions
- Salivary pH
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 24 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jan 2024 (actual)
- Primary completion
- 1 Jul 2024 (actual)
- Study completion
- 1 Jul 2024 (actual)
- First posted
- 17 Jul 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Objectives: To evaluate the effect of green tea versus matcha tea on the salivary pH in high caries risk patients. Materials and methods: Total number of high caries risk patients were randomized into two equal groups (n=). Group 1 (intervention group) was given Matcha Tea and Group 2 (control group) was given green tea. A portable digital pH meter was used to measure the salivary pH at baseline and after consumption tea immediately, after 5 mins and after 10 mins.
Detailed description
Study Settings:
The study will be carried out at the Conservative Dentistry Department, Faculty of Dentistry, Cairo University in Egypt. Ethical approval will be taken from the Research Ethics Committee of the faculty of Dentistry, Cairo University. Signed informed consent will be signed each participant.
Recruitment:
Participants will be recruited from the patients' flow at the clinics of the Conservative Dentistry Department of Faculty of Dentistry, Cairo university.
Materials:
The Commercially available green tea and matcha tea for this study will be Lipton Tea. For preparation of green tea, 2 gr of green tea will be poured into 150 mL boiling water (100°C), after 3 minutes, it will be ready for drinking. As well as for matcha tea, 3 gr of green tea will be poured into 150 mL hot water (70°C), after 3 minutes, it will be ready drinking(7) .
Methods:
On the study day, all subjects will be instructed to brush their teeth 45 minutes after eating breakfast. Between 9-11 a.m., saliva samples will be collected through spitting method, one hour after breakfast and 15 minutes after brushing(7)
. For making the subjects blind to which tea they are drinking, the prepared tea will be served in the dark glasses. After drinking the green tea and matcha tea, every subject will be asked to bend his head forward and spit his saliva into laboratory tube every 60 seconds for 2-5 minutes. Samples will be collected immediately and 5 minutes after drinking tea(7)
.
.
Aim of the study:
The aim of this study is to evaluate the effect of green tea versus matcha tea on the salivary pH in high caries risk patients.
Research question:
In high caries risk patients, will matcha tea have the same effect as green tea on salivary pH?
PICOTS:
P: High caries risk patients I: Matcha tea C: Green tea O: Salivary pH T: T1: baseline T2: immediately T3: 5 mins T4: 10 mins
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- Randomized Controlled Trial
| Arm | Type | Receives |
|---|---|---|
| Green Tea | Active comparator | Procedure: Green TeaGreen tea contains a significant amount of catechins, which are subgroup of flavonoids and play a vital role in maintaining health having strong bactericidal as well as antibacterial activity |
| Matcha Tea | Experimental | Procedure: Matcha TeaMatcha, powder of specially cultivated tea leaves, is gaining popularity in functional food and other food markets all over the world. Various studies have reported the difference in bioactive compounds in matcha as compared to green tea and other tea formulations |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (6 listed)
- -
- 1. High caries risk patients
- Satisfactory cooperative behavior
- Age between 20-45 years old
- Males or females
Key exclusion criteria (1 listed)
- 1. Systemic diseases 2. Drug consumption during 3 past months 3. Salivary gland disorders 4. History of radiotherapy 5. Smoking
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Matcha TeaJapanese tea rich in antioxidants and Catechins | Procedure or surgery | Matcha Tea |
| Green TeaGreen tea rich in catechins | Procedure or surgery | Green Tea |
Primary outcome
salivary pH
Time frame: baseline before administration of tea, immediately after administration of tea, 5 minutes after administration of tea and 10 minutes after administration of tea
pH of saliva to be measured
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Jul 2024.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Matcha Tea and Green Tea in people with Salivary pH, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Jul 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
salivary pH (time frame: baseline before administration of tea, immediately after administration of tea, 5 minutes after administration of tea and 10 minutes after administration of tea). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Jul 2024.