Primary CareNCT06526663
Randomizing Vignettes to Understand Contributors to Trust in Primary Care Doctors
A study testing vignette exposure in people with Primary Care, run by Johns Hopkins University at 2 sites in United States.
Trial summary
In this proposed work, the investigators plan to generate experimental evidence about trust and overuse of healthcare. The protocol described below is for the first phase of this work to establish the feasibility of modifying feelings of trust via a vignette. Read more about this study
- Who is it for?
- Ages 18 to 95 yearsHealthy volunteers can take part
- Conditions the study is for
- Primary Care
- What is being tested?
- vignette exposure
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,106 participants
- Where
- 2 sitesUnited States
- Study dates
- 15 Aug 2024to 26 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 95 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Participants will be over the age of 18 years,
- able to read and respond in English, and
- have had one or more visits with a doctor in the past 3 years
- will be registered MTURK workers
Who cannot join
- None
Trial locations and contacts
2 sites in 1 country.
United States2 sites
Johns Hopkins University
Baltimore, Maryland, 21205
Virginia Tech
Blacksburg, Virginia, 24061
About this study
In this proposed work, the investigators plan to generate experimental evidence about trust and overuse of healthcare. The protocol described below is for the first phase of this work to establish the feasibility of modifying feelings of trust via a vignette.
Read the detailed description
The investigators will engage survey participants by recruiting from among the "Workers" registered with Amazon Mechanical Turk (MTurk). These are paid participants who chose to participate in this anonymous, low-risk activity. After pilot testing on a small set of Workers, the investigators will field the full survey using a randomized design to test hypotheses about the investigators ability to manipulate trust experimentally.
Individuals eligible as participants will be over the age of 18 years, able to read and respond in English, and have had one or more visits with a doctor in the past 3 years.
Survey
The survey has three parts. The investigators will use Qualtrics to develop the survey vignette and use the randomization feature of Qualtrics to randomize the participants when the participant clicks on the link to Qualtrics.
- Vignette Participants will be randomized to view one of sixteen vignettes. The vignettes describe a clinical encounter and vary four attributes, each of which has two levels. Duration of relationship with doctor: No previous relationship (episodic care, walk-in-care, on demand telemedicine) versus > 3 years; Connection: Physician is attending to computer versus Physician is attending to patient; Length of visit: 15 minutes versus 30 minutes; Shares information: Doctor does not explain the decision making versus Doctor shares what he/she knows that informed the decision A sample vignette is presented here: Imagine having low back pain that started 4 days ago and being very uncomfortable. For this visit, the patient sees a doctor at the usual practice that the patient has never met before. The doctor spends 30 minutes with the patient. He is primarily looking at the computer screen and not at the patient. At the end, the doctor tells the patient that no xrays are needed and makes recommendations for treating the patient's pain. The investigators will do a test of attention quiz to assure that the participant read the vignette asking:
- Why did you go for care? (twisted ankle, back pain)
- Did the doctor make any recommendations? (recommended pain treatment, recommended a cast)
- Trust in Clinician Survey.
The investigators will use the Wake Forest Trust in Physician (WFTP) scale slightly modified to clarify that the investigators are inquiring about the clinician described in the vignette. Whereas the WFTP scale asks about "your doctor", the investigators will ask about "this doctor". The WFTP uses a 5-pt Likert scale. Items 2, 3, and 8 are reverse coded upon analysis (strongly agree, agree, neutral, disagree, strongly disagree).
The introduction will read:
Think about the visit described above. What do you think about this doctor?
- This doctor will do whatever it takes to get you all the care you need.
- Sometimes this doctor cares more about what is convenient for [him or her] than about the patient's medical needs.
- This doctor's medical skills are not as good as they should be.
- This doctor is extremely thorough and careful.
- You completely trust this doctors decisions about which medical treatments are best for you.
- This doctor is totally honest in telling you about all of the different treatment options available for the patient's condition.
- This doctor only thinks about what is best for you.
- Sometimes this doctor does not pay full attention to what you are trying to tell [him or her].
- The patient has no worries about putting the patient's life in this doctor's hands.
- All in all, the patient has complete trust in this doctor.
- Demographics
The investigators will ask the respondents to describe themselves as follows:
Sex (Male, Female, Non-binary) Age (18-35, 36-50, 51-65, >=65) Race/Ethnicity (Black, White, Asian, Native American/Pacific Islander, Hispanic, Other) Choose all that apply How do you describe your health? Excellent, Very good, Good, Fair, Poor Do you have health insurance? Yes or No What is your highest level of education completed? Grade school, High School, college, post-graduate
Analysis The investigators will use descriptive statistics to describe the characteristics of the respondents and the distribution of the WFTP score, which is a quasi-continuous measure. The investigators will look for outliers defined as scores greater or less than 3.2 standard deviations from the mean. Linearity will be examined with scatterplots. The assumption of normality will be assessed by analyzing the skewness and kurtosis of the variables and with use of histograms. The investigators expect the WFTP to be normally distributed as it has been in other populations. If it is not, the investigators will consider log transformation. The investigators will describe the respondents by vignette assignment to confirm that randomization was successful.
Given the structure of MTurk, the investigators will not have a measure of survey response. The investigators will, however, be able to assess the pattern of missing variables across the responses and will incorporate this appropriately into the models.
In the validation study by Katz, she reports in a national sample, the Wake Forest Physician Trust Scale (WFPTS) had a mean score of 40.8 (SD = 6.2) for the national sample of 959 participants. In her study of fewer participants recruited from MTurk, the mean score for the WFPTS was 35.9 (SD = 6.12) for young adult participants and 36.1 (SD = 6.11) for older adult participants.
The investigators would like to be able to detect a 2 standard deviation (SD) difference between the lower trust vignettes and the higher trust vignettes. If the study has 36 individuals in each group, the investigators are able to detect, with a power of 0.8 and an alpha of 0.5, a difference of 4 points on the WFTP (38 (sd 6) vs 42 (sd 6)). The investigators will aim to have 36 respondents in each of 16 groups.
The investigators will test hypotheses about the vignettes and the reported trust in the physician.
For the second round of the survey, investigators will randomize to only 4 arms depending on the results of the first round. The investigators will randomize 100 individuals (50 men and 50 women) to each of the 4 arms.
- Conditions
- Primary Care
- Being tested
- vignette exposure
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
vignette exposureBehavioural
Participants will be randomized to be exposed to one of 16 written vignettes that vary four elements of the primary care experience. The four attributes can take two levels.
In the second round, individuals will be randomized to only 4 different vignettes.
| Study group | Role | What they receive |
|---|---|---|
| Vignette1 | Active comparator | abbb Receives: Behavioral: vignette exposure |
| Vignette2 | Active comparator | aabb Receives: Behavioral: vignette exposure |
| Vignette3 | Active comparator | aaab Receives: Behavioral: vignette exposure |
| Vignette4 | Active comparator | aaaa Receives: Behavioral: vignette exposure |
| Vignette5 | Active comparator | babb Receives: Behavioral: vignette exposure |
| Vignette6 | Active comparator | baab Receives: Behavioral: vignette exposure |
| Vignette7 | Active comparator | baaa Receives: Behavioral: vignette exposure |
| Vignette8 | Active comparator | abaa Receives: Behavioral: vignette exposure |
| Vignette9 | Active comparator | abba Receives: Behavioral: vignette exposure |
| Vignette10 | Active comparator | bbab Receives: Behavioral: vignette exposure |
| Vignette11 | Active comparator | bbaa Receives: Behavioral: vignette exposure |
| Vignette12 | Active comparator | bbba Receives: Behavioral: vignette exposure |
| Vignette13 | Active comparator | bbbb Receives: Behavioral: vignette exposure |
| Vignette14 | Active comparator | baba Receives: Behavioral: vignette exposure |
| Vignette15 | Active comparator | abab Receives: Behavioral: vignette exposure |
| Vignette16 | Active comparator | aaba Receives: Behavioral: vignette exposure |
What is being measured
The primary outcome is the main question the study is designed to answer.
Wake Forest Physician Trust Scale (10 item survey)
Scores range from 10-50 with higher scores indicating higher trust
Measured: Immediately upon completing exposure to the vignette
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Jul 2024
- Study start15 Aug 2024
- Primary completion26 Dec 2024
- Study completion26 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Primary CareStudies of the same condition, open and under way.
- More trials run by Johns Hopkins UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 1,106 participants (actual)
Sponsor and investigators
- Lead sponsor
- Johns Hopkins University
- Sponsor type
- University, hospital or other
- Collaborators
- Virginia Polytechnic Institute and State University, National Institute on Aging (NIA)
- Responsible party
- Sponsor
- Investigators
- Jodi Segal, MD, MPH, Principal investigator, Johns Hopkins University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06526663
- Sponsor's protocol ID
- IRB00447825
- Other IDs
- K24AG049036
- Status last verified
- Nov 2025
- First submitted
- 25 Jul 2024
- Last updated
- 17 Nov 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Individual Participant Data without identifiers will be shared upon request.
Study at a glance
From the registry record, last updated by the sponsor on 17 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Randomizing Vignettes to Understand Contributors to Trust in Primary Care Doctors
- ClinicalTrials.gov ID
- NCT06526663
- Acronym / sponsor ID
- IRB00447825
- Conditions
- Primary Care
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 1,106 participants (actual)
- Lead sponsor
- Johns Hopkins UniversityUniversity, hospital or other
- Collaborators
- Virginia Polytechnic Institute and State University, National Institute on Aging (NIA)
- Study start
- 15 Aug 2024 (actual)
- Primary completion
- 26 Dec 2024 (actual)
- Study completion
- 26 Dec 2024 (actual)
- First posted
- 30 Jul 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In this proposed work, the investigators plan to generate experimental evidence about trust and overuse of healthcare. The protocol described below is for the first phase of this work to establish the feasibility of modifying feelings of trust via a vignette.
Detailed description
The investigators will engage survey participants by recruiting from among the "Workers" registered with Amazon Mechanical Turk (MTurk). These are paid participants who chose to participate in this anonymous, low-risk activity. After pilot testing on a small set of Workers, the investigators will field the full survey using a randomized design to test hypotheses about the investigators ability to manipulate trust experimentally.
Individuals eligible as participants will be over the age of 18 years, able to read and respond in English, and have had one or more visits with a doctor in the past 3 years.
Survey
The survey has three parts. The investigators will use Qualtrics to develop the survey vignette and use the randomization feature of Qualtrics to randomize the participants when the participant clicks on the link to Qualtrics.
- Vignette Participants will be randomized to view one of sixteen vignettes. The vignettes describe a clinical encounter and vary four attributes, each of which has two levels. Duration of relationship with doctor: No previous relationship (episodic care, walk-in-care, on demand telemedicine) versus > 3 years; Connection: Physician is attending to computer versus Physician is attending to patient; Length of visit: 15 minutes versus 30 minutes; Shares information: Doctor does not explain the decision making versus Doctor shares what he/she knows that informed the decision A sample vignette is presented here: Imagine having low back pain that started 4 days ago and being very uncomfortable. For this visit, the patient sees a doctor at the usual practice that the patient has never met before. The doctor spends 30 minutes with the patient. He is primarily looking at the computer screen and not at the patient. At the end, the doctor tells the patient that no xrays are needed and makes recommendations for treating the patient's pain. The investigators will do a test of attention quiz to assure that the participant read the vignette asking:
- Why did you go for care? (twisted ankle, back pain)
- Did the doctor make any recommendations? (recommended pain treatment, recommended a cast)
- Trust in Clinician Survey.
The investigators will use the Wake Forest Trust in Physician (WFTP) scale slightly modified to clarify that the investigators are inquiring about the clinician described in the vignette. Whereas the WFTP scale asks about "your doctor", the investigators will ask about "this doctor". The WFTP uses a 5-pt Likert scale. Items 2, 3, and 8 are reverse coded upon analysis (strongly agree, agree, neutral, disagree, strongly disagree).
The introduction will read:
Think about the visit described above. What do you think about this doctor?
- This doctor will do whatever it takes to get you all the care you need.
- Sometimes this doctor cares more about what is convenient for [him or her] than about the patient's medical needs.
- This doctor's medical skills are not as good as they should be.
- This doctor is extremely thorough and careful.
- You completely trust this doctors decisions about which medical treatments are best for you.
- This doctor is totally honest in telling you about all of the different treatment options available for the patient's condition.
- This doctor only thinks about what is best for you.
- Sometimes this doctor does not pay full attention to what you are trying to tell [him or her].
- The patient has no worries about putting the patient's life in this doctor's hands.
- All in all, the patient has complete trust in this doctor.
- Demographics
The investigators will ask the respondents to describe themselves as follows:
Sex (Male, Female, Non-binary) Age (18-35, 36-50, 51-65, >=65) Race/Ethnicity (Black, White, Asian, Native American/Pacific Islander, Hispanic, Other) Choose all that apply How do you describe your health? Excellent, Very good, Good, Fair, Poor Do you have health insurance? Yes or No What is your highest level of education completed? Grade school, High School, college, post-graduate
Analysis The investigators will use descriptive statistics to describe the characteristics of the respondents and the distribution of the WFTP score, which is a quasi-continuous measure. The investigators will look for outliers defined as scores greater or less than 3.2 standard deviations from the mean. Linearity will be examined with scatterplots. The assumption of normality will be assessed by analyzing the skewness and kurtosis of the variables and with use of histograms. The investigators expect the WFTP to be normally distributed as it has been in other populations. If it is not, the investigators will consider log transformation. The investigators will describe the respondents by vignette assignment to confirm that randomization was successful.
Given the structure of MTurk, the investigators will not have a measure of survey response. The investigators will, however, be able to assess the pattern of missing variables across the responses and will incorporate this appropriately into the models.
In the validation study by Katz, she reports in a national sample, the Wake Forest Physician Trust Scale (WFPTS) had a mean score of 40.8 (SD = 6.2) for the national sample of 959 participants. In her study of fewer participants recruited from MTurk, the mean score for the WFPTS was 35.9 (SD = 6.12) for young adult participants and 36.1 (SD = 6.11) for older adult participants.
The investigators would like to be able to detect a 2 standard deviation (SD) difference between the lower trust vignettes and the higher trust vignettes. If the study has 36 individuals in each group, the investigators are able to detect, with a power of 0.8 and an alpha of 0.5, a difference of 4 points on the WFTP (38 (sd 6) vs 42 (sd 6)). The investigators will aim to have 36 respondents in each of 16 groups.
The investigators will test hypotheses about the vignettes and the reported trust in the physician.
For the second round of the survey, investigators will randomize to only 4 arms depending on the results of the first round. The investigators will randomize 100 individuals (50 men and 50 women) to each of the 4 arms.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 16
| Arm | Type | Receives |
|---|---|---|
| Vignette1 | Active comparator | Behavioral: vignette exposureabbb |
| Vignette2 | Active comparator | Behavioral: vignette exposureaabb |
| Vignette3 | Active comparator | Behavioral: vignette exposureaaab |
| Vignette4 | Active comparator | Behavioral: vignette exposureaaaa |
| Vignette5 | Active comparator | Behavioral: vignette exposurebabb |
| Vignette6 | Active comparator | Behavioral: vignette exposurebaab |
| Vignette7 | Active comparator | Behavioral: vignette exposurebaaa |
| Vignette8 | Active comparator | Behavioral: vignette exposureabaa |
| Vignette9 | Active comparator | Behavioral: vignette exposureabba |
| Vignette10 | Active comparator | Behavioral: vignette exposurebbab |
| Vignette11 | Active comparator | Behavioral: vignette exposurebbaa |
| Vignette12 | Active comparator | Behavioral: vignette exposurebbba |
| Vignette13 | Active comparator | Behavioral: vignette exposurebbbb |
| Vignette14 | Active comparator | Behavioral: vignette exposurebaba |
| Vignette15 | Active comparator | Behavioral: vignette exposureabab |
| Vignette16 | Active comparator | Behavioral: vignette exposureaaba |
Who may qualify
- Ages
- 18 to 95 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Participants will be over the age of 18 years,
- able to read and respond in English, and
- have had one or more visits with a doctor in the past 3 years
- will be registered MTURK workers
Key exclusion criteria (1 listed)
- None
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| vignette exposureParticipants will be randomized to be exposed to one of 16 written vignettes that vary four elements of the primary care experience. The four attributes can take two levels. In the second round, individuals will be randomized to only 4 different vignettes. | Behavioural | Vignette1, Vignette10, Vignette11, Vignette12, Vignette13, Vignette14, Vignette15, Vignette16, Vignette2, Vignette3, Vignette4, Vignette5, Vignette6, Vignette7, Vignette8, Vignette9 |
Primary outcome
Wake Forest Physician Trust Scale (10 item survey)
Time frame: Immediately upon completing exposure to the vignette
Scores range from 10-50 with higher scores indicating higher trust
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Nov 2025.
- Individual participant dataSharing planned: Yes. Individual Participant Data without identifiers will be shared upon request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Jodi Segal, MD, MPH principal investigator
Johns Hopkins University
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing vignette exposure in people with Primary Care, run by Johns Hopkins University at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Wake Forest Physician Trust Scale (10 item survey) (time frame: Immediately upon completing exposure to the vignette). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Nov 2025.