Hyperkypohsis and Impaired Lung FunctionNCT06530056
Costovertebral Mobilization on Kyphotic Posture and Lung Function in Non-Smoker
A study testing Costovertebral Mobilization+Conventional Therapy and Conventional Therapy in people with Hyperkypohsis and Impaired Lung Function, run by Riphah International University at 1 site in Pakistan.
Trial summary
Aim of this study is to find the effects of Costoverterbral Mobilization on Thoracic kyphosis and Lung function in non-smoker. A randomized control trial that will include total 44 participants.The first group will receive Costovertebral Mobilization along with conventional therapy and 2nd group will receive… Read more about this study
- Who is it for?
- Ages 20 to 40 years
- Conditions the study is for
- Hyperkypohsis and Impaired Lung Function
- What is being tested?
- Costovertebral Mobilization+Conventional Therapy and Conventional Therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 44 participants
- Where
- 1 sitePakistan
- Study dates
- 8 Aug 2024to 10 Jan 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Non smoker
- Age: 20-40 years
- Normal Body Mass Index 18.5 To 24.9
- Both female and male gender
- Decrease forced expiratory volume-one second/ forced vital capacity ratio greater than or equal to 70%
- Increase Thoracic kyphotic posture greater than or equal to 40˚
Who cannot join
- Any respiratory disease of the upper or lower respiratory tracts e.g. asthma, chronic bronchitis, COPD, emphysema etc. which could altered the optimal lung functioning.
- Previous history of rib fractures, dislocations, sprains of costochondral, costosternal and interchondral joints.
- Smokers
- Scheuermann Disease
- Primary and Secondary neoplastic lesions of the spine and/or ribs
- Obvious advanced spinal deformity e.g. kyphoscoliosis
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- Infection e.g. tuberculosis
- Primary and secondary neoplastic lesions of the soft tissue structures of the chest
- Inflammation e.g. acute rheumatoid arthritis or ankylosing spondylitis
Trial locations and contacts
1 site in 1 country.
Pakistan1 site, 1 recruiting
- Recruiting
Madiha Ali
Islamabad, 44000
Madiha Ali, MSOMPT, 03313360064, madiha.ali@riphah.edu.pk
Rida Mumtaz, MSOMPT *
About this study
Official title: Effects of Costovertebral Mobilization on Kyphotic Posture and Lung Function in Non Smoker
Aim of this study is to find the effects of Costoverterbral Mobilization on Thoracic kyphosis and Lung function in non-smoker. A randomized control trial that will include total 44 participants.The first group will receive Costovertebral Mobilization along with conventional therapy and 2nd group will receive conventional therapy.Data collected will be analyzed through SPSS 25
Read the detailed description
Kyphosis is the curvature of the thoracic spine, formed by the shape of the vertebrae and the intervertebral discs and-in standing position-paraspinal muscle strength. Hyperkyphosis is usually associated with increased anteroposterior diameter of the thorax and a decrease in the distance between the xiphisternum and pubis and it is present when the kyphosis angle exceeds the normal ranges. This curve is concave anteriorly with a normal angle between 20˚ - 40˚.
The lungs are the foundational organs of the respiratory system,whose most basic function is to facilitate gas exchange from the environment into the bloodstream.The decline in lung function could be associated with hyperkyphosis, As the curvature of the thoracic spine increases and the posture becomes more hunched, the mobility of the rib cage could be limited and restrict the thoracic and lung expansions during inspiratory maneuver.
Different treatment strategies such as surgery, splinting, exercises and manual therapies such as massage, muscle energy technique, and passive joint mobilization have been used to treat hyperkyphosis. Costovertebral mobilization is a manual therapy technique, to improve the mobility and function of the joints between the ribs (costo) and the vertebrae (vertebral). This technique increases the range of motion of ribcage and spine, thus improve kyphosis posture and lung functions.
- Conditions
- Hyperkypohsis and Impaired Lung Function
- Being tested
- Costovertebral Mobilization+Conventional Therapy, Conventional Therapy
- Keywords
- Hyperkyphosis, Pulmonary Functions, Costoverterbral Mobilization, FEV1/FVC, Cobb Angle
- Medical subject headings
- Kyphosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Costovertebral Mobilization+Conventional TherapyOther
Patient would receive costovertebral mobilization in side lying position for left 10th to 6th, in sitting position for right 10th to 2nd rib and in supine lying position for 1st rib.
Conventional Therapy:
Hot pack 10 mints, Posture corrective exercises, Breathing exercises Frequency; 4 times/week for 3 weeks
Conventional TherapyOther
Electrotherapy:
- Hot Pack 10 minutes
Posture Corrective Exercises:
- Thoracic Rotation 10 rep/session
- Thoracic extension 10 rep/session
- Scapular retraction 5 rep/session
- Deep neck flexor Isometric 5 rep/session
Deep Breathing Exercises:
- Pursed lip breathing 10 repetition in one session
| Study group | Role | What they receive |
|---|---|---|
| Costovertebral Mobilization+Conventional Therapy | Experimental | Costovertebral mobilization:
It will be performed in 3 Different Positions to target specific regions of rib cage.
Conventional Therapy:
Hot pack 10 mints, Posture corrective exercises, Breathing exercises. Receives: Other: Costovertebral Mobilization+Conventional Therapy |
| Conventional Therapy | Other | Conventional Therapy:
Hot pack 10 mints, Posture corrective exercises, Breathing exercises Receives: Other: Conventional Therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
X-RAY
X-ray is a gold standard method for objective assessment of Thoracic Kyphosis.
Measured: 3 weeks
Secondary outcomes (1)
Spirometer
For measurement of forced expiratory volume-one second/ Forced vital capacity ratio (Pulmonary Function Tests).
Measured: 3 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Jul 2024
- Study start8 Aug 2024
- Primary completion30 Dec 2024 (estimated)
- Study completion10 Jan 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hyperkypohsis and Impaired Lung FunctionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 44 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Madiha Ali, MSOMPT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06530056
- Sponsor's protocol ID
- Rida Mumtaz
- Status last verified
- Aug 2024
- First submitted
- 28 Jul 2024
- Last updated
- 14 Aug 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Aug 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Costovertebral Mobilization on Kyphotic Posture and Lung Function in Non Smoker
- ClinicalTrials.gov ID
- NCT06530056
- Acronym / sponsor ID
- Rida Mumtaz
- Conditions
- Hyperkypohsis and Impaired Lung Function
- Keywords
- Hyperkyphosis, Pulmonary Functions, Costoverterbral Mobilization, FEV1/FVC, Cobb Angle
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 44 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 8 Aug 2024 (actual)
- Primary completion
- 30 Dec 2024 (estimated)
- Study completion
- 10 Jan 2025 (estimated)
- First posted
- 31 Jul 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Aim of this study is to find the effects of Costoverterbral Mobilization on Thoracic kyphosis and Lung function in non-smoker. A randomized control trial that will include total 44 participants.The first group will receive Costovertebral Mobilization along with conventional therapy and 2nd group will receive conventional therapy.Data collected will be analyzed through SPSS 25
Detailed description
Kyphosis is the curvature of the thoracic spine, formed by the shape of the vertebrae and the intervertebral discs and-in standing position-paraspinal muscle strength. Hyperkyphosis is usually associated with increased anteroposterior diameter of the thorax and a decrease in the distance between the xiphisternum and pubis and it is present when the kyphosis angle exceeds the normal ranges. This curve is concave anteriorly with a normal angle between 20˚ - 40˚.
The lungs are the foundational organs of the respiratory system,whose most basic function is to facilitate gas exchange from the environment into the bloodstream.The decline in lung function could be associated with hyperkyphosis, As the curvature of the thoracic spine increases and the posture becomes more hunched, the mobility of the rib cage could be limited and restrict the thoracic and lung expansions during inspiratory maneuver.
Different treatment strategies such as surgery, splinting, exercises and manual therapies such as massage, muscle energy technique, and passive joint mobilization have been used to treat hyperkyphosis. Costovertebral mobilization is a manual therapy technique, to improve the mobility and function of the joints between the ribs (costo) and the vertebrae (vertebral). This technique increases the range of motion of ribcage and spine, thus improve kyphosis posture and lung functions.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Costovertebral Mobilization+Conventional Therapy | Experimental | Other: Costovertebral Mobilization+Conventional TherapyCostovertebral mobilization: It will be performed in 3 Different Positions to target specific regions of rib cage. Conventional Therapy: Hot pack 10 mints, Posture corrective exercises, Breathing exercises. |
| Conventional Therapy | Other | Other: Conventional TherapyConventional Therapy: Hot pack 10 mints, Posture corrective exercises, Breathing exercises |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Non smoker
- Age: 20-40 years
- Normal Body Mass Index 18.5 To 24.9
- Both female and male gender
- Decrease forced expiratory volume-one second/ forced vital capacity ratio greater than or equal to 70%
Key exclusion criteria (9 listed)
- Any respiratory disease of the upper or lower respiratory tracts e.g. asthma, chronic bronchitis, COPD, emphysema etc. which could altered the optimal lung functioning.
- Previous history of rib fractures, dislocations, sprains of costochondral, costosternal and interchondral joints.
- Smokers
- Scheuermann Disease
- Primary and Secondary neoplastic lesions of the spine and/or ribs
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Costovertebral Mobilization+Conventional TherapyPatient would receive costovertebral mobilization in side lying position for left 10th to 6th, in sitting position for right 10th to 2nd rib and in supine lying position for 1st rib. Conventional Therapy: Hot pack 10 mints, Posture corrective exercises, Breathing exercises Frequency; 4 times/week for 3 weeks | Other | Costovertebral Mobilization+Conventional Therapy |
| Conventional TherapyElectrotherapy: • Hot Pack 10 minutes Posture Corrective Exercises: * Thoracic Rotation 10 rep/session * Thoracic extension 10 rep/session * Scapular retraction 5 rep/session * Deep neck flexor Isometric 5 rep/session Deep Breathing Exercises: • Pursed lip breathing 10 repetition in one session | Other | Conventional Therapy |
Primary outcome
X-RAY
Time frame: 3 weeks
X-ray is a gold standard method for objective assessment of Thoracic Kyphosis.
1 secondary outcome
Spirometer
Time frame: 3 weeks
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Aug 2024.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Madiha Ali, MSOMPT principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Costovertebral Mobilization+Conventional Therapy and Conventional Therapy in people with Hyperkypohsis and Impaired Lung Function, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 14 Aug 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Madiha Ali, MSOMPT (0331-3360064, madiha.ali@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
X-RAY (time frame: 3 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Aug 2024.