EndometriosisNCT06559852
The Impact of Yoga on Endometriosis-Related Pain
A study testing Yoga in people with Endometriosis, run by Milton S. Hershey Medical Center at 1 site in United States.
Trial summary
The central hypothesis of the investigators is that the practice of yoga will result in an improvement of endometriosis related pain symptoms for women with endometriosis. Read more about this study
- Who is it for?
- Ages 18 to 45 years
- Conditions the study is for
- Endometriosis
- What is being tested?
- Yoga
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteUnited States
- Study dates
- 15 Oct 2026to 30 Apr 2027
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Reproductive aged women 18-45
- Self-reported prior surgery with pathology confirming a diagnosis of endometriosis
- No current use of yoga
- Baseline moderate pain, score greater than or equal to 5 on VAS scoring
- Access to internet with wifi capability for zoom platform and completion of weekly surveys
- Access to items required for yoga session participation (2 blankets or towels, firm pillow, stable chair, wall space, comfortable clothing, water)
- Ability to commit to duration of 12-week yoga course
Who cannot join
- Pregnant patients
- Established yoga participation or moderate exercise regimen
- Physical trauma or disability
- Planned surgery or hormonal medication change during study
- Non-English speaking patients
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Penn State Health
Hershey, Pennsylvania, 17033
Ashlie Carter, MD, 7175313503, acarter8@pennstatehealth.psu.edu
About this study
The central hypothesis of the investigators is that the practice of yoga will result in an improvement of endometriosis related pain symptoms for women with endometriosis.
Read the detailed description
Yoga has been demonstrated to improve menstrual pain associated with primary dysmenorrhea through use of physical exercises, mental meditation, and breathing techniques. Still, there has been limited studies assessing potential benefits of yoga on pain symptoms of endometriosis. It is important to further assess yoga as a complementary therapy for women with endometriosis.
- Conditions
- Endometriosis
- Being tested
- Yoga
- Keywords
- Pelvic Pain
- Medical subject headings
- Endometriosis, Pelvic Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
YogaBehavioural
Participants will engage in a 12-week virtual yoga course to assess impact on endometriosis-related pain
| Study group | Role | What they receive |
|---|---|---|
| Yoga Intervention | Experimental | Not described Receives: Behavioral: Yoga |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Endometriosis Health Profile-30 Pain Score
Identify the impact of yoga on endometriosis related pain based on the Endometriosis Health Profile-30, with specific focus on the domain of pain. The EHP-30 questionnaire consists of five scales which includes pain, control and powerlessness, emotional well-being, social support, and self-image and a total of 30 questions. Each scale is translated into a score ranging from 0, or the best health status, to 100, the worst health status.
Measured: Baseline to completion at 12-weeks
Secondary outcomes (1)
Change in Visual Analog Scale scores
Comparison of visual analog scale scores from start to the end of the study. The visual analog scale is a validated scale for measuring acute and chronic pain. Scores are recorded on a scale between 0 or "no pain" and 10, the "worst pain".
Measured: Baseline to completion at 12-weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Aug 2024
- Study start15 Oct 2026 (estimated)
- Primary completion30 Mar 2027 (estimated)
- Study completion30 Apr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for EndometriosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Milton S. Hershey Medical Center
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Linda Li, Milton S. Hershey Medical Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06559852
- Sponsor's protocol ID
- STUDY00025723
- Status last verified
- Oct 2026
- First submitted
- 15 Aug 2024
- Last updated
- 6 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Plan to publish in an ICMJE journal upon completion of study.