Overweight and ObesityNCT06584708
Effect of Low-Volume HIT vs. MIC Exercise in Individuals With Increased BMI
A study testing Low-volume high intensity interval training and Moderate intensity continuous exercise in people with Overweight and Obesity, run by Riphah International University at 1 site in Pakistan.
Trial summary
To compare the effect of low volume high intensity training and moderate intensity continuous exercise on Rate Pressure Product (RPP) and functional capacity. Limited literature available on effectiveness of Low-volume HIIT in comparison of other Aerobic interventions in obese individuals. Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Overweight and Obesity
- What is being tested?
- Low-volume high intensity interval training and Moderate intensity continuous exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 sitePakistan
- Study dates
- 15 Feb 2024to 1 Sep 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Body mass index 23-29.9 kg/m 2 (Overweight-Type I Obese)
- Able to do exercise (PAR-Q)
Who cannot join
- History of chronic diseases and medication use
- Considerable mental or physical disability, neurological or musculoskeletal problems
- Severe personality disorders or drug addiction.
- Pregnant females
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Cantonment General Hospital, Saddar
Rawalpindi, Punjab Province, 46060
About this study
Official title: Effect of Low-Volume High-Intensity Training vs. Moderate Intensity Continuous Exercise on Rate Pressure Product and Functional Capacity in Individuals With Increased BMI
To compare the effect of low volume high intensity training and moderate intensity continuous exercise on Rate Pressure Product (RPP) and functional capacity. Limited literature available on effectiveness of Low-volume HIIT in comparison of other Aerobic interventions in obese individuals. In our community, people are sedentary and not involved in routine exercise because of increased weight, so Low volume HIIT would be safe and convenient for such individuals to perform. There is also limited studies available on female gender so both genders are included in this study.
Read the detailed description
Some recent studies suggest that the rising interest for the potential of high- intensity interval training (HIIT) to enhance the metabolic health in overweight adults. HIIT has also been found to induce comparatively fast enhancements in overall-body aerobic capacity and muscle mitochondrial markers in individuals with overweight.
The main advantage of HIIT is that low-volume HIIT protocols can involve a shorter time as compared with MICT, and time limitations have been recognized as a generally reported hurdle to daily exercise involvement.
Latest studies propose that's when compared to moderate intensity continuous training (MICT), HIIT has been shown to produce similar and sometimes better improvements in results such as cardiorespiratory fitness in spite of often demanding a smaller amount of time commitment and lesser energy expenditure. On the other hand, low volume HIIT is still undecided whether this form of physical training is superior, equivalent or inferior to more outdated forms of exercise training such as MICT for the management cardio metabolic health.
- Conditions
- Overweight and Obesity
- Being tested
- Low-volume high intensity interval training, Moderate intensity continuous exercise
- Keywords
- Low volume High intensity training, Moderate Intensity Continous Exercise, Rate Pressure product, Functional capacity, Increased BMI
- Medical subject headings
- Overweight, Obesity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Low-volume high intensity interval trainingOther
Week 1 \& 2:
Warm-up: 10 minutes at 50% THR Work: 1x4 minutes at 80% THR followed by 1*4 minutes Recovery at 50% THR Cool down: 5 minutes at 50% THR Total exercise time: 23 minutes
Week 3 \& 4:
Warm-up: 10 minutes at 50% THR Work: 2x6 minutes at 80% THR followed by 1*6 minutes Recovery at 50% THR Cool down: 5 minutes at 50% THR Total exercise time: 33 minutes
Moderate intensity continuous exerciseOther
Week 1 \& 2:
Warm-up: 5 minutes at 50% THR Work: 20 minutes at 60% VO 2 THR Cool Down: 5 minutes at 50% THR Total exercise time: 30 minutes
Week 3 \& 4:
Warm-up: 5 minutes at 50% THR Work: 30 minutes at 60% THR Cool Down: 5 minutes at 50% THR Total exercise time: 40 minutes
| Study group | Role | What they receive |
|---|---|---|
| Low-volume High intensity interval training | Experimental | Group A: Low-volume High intensity interval training Receives: Other: Low-volume high intensity interval training |
| Moderate intensity continous exercise | Experimental | Group B: Moderate intensity continous exercise Receives: Other: Moderate intensity continuous exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
Rate Pressure Product
Changes from baseline to 2 weeks and 4 weeks after the intervention, measured through product of heart rate and systolic blood pressure, is a very reliable indicator of myocardial oxygen demand. An RPP above 20,000 mmHg per minute is considered healthy, whereas anything below 16,000 mmHg is considered insufficient.
Measured: 2 weeks, 4 weeks
Functional Capacity
Changes from baseline to 2 weeks and 4 weeks after the intervention, measured through 6 min walk test (6 MWT). It is a submaximal exercise test that can aid in assessing the functional/exercise capacity of patients with cardiopulmonary diseases, in this test we find out the maximum distance in meters that an individual covers in 6 min without any support.
Measured: 2 Weeks, 4 Weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Sep 2024
- Study start15 Feb 2024
- Primary completion1 Sep 2024
- Study completion1 Sep 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Overweight and ObesityStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Mehwish Waseem, MSPT-CPPT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06584708
- Sponsor's protocol ID
- Rec/01817 Asma Rehman
- Status last verified
- Nov 2024
- First submitted
- 2 Sep 2024
- Last updated
- 22 Nov 2024
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Nov 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Low-Volume High-Intensity Training vs. Moderate Intensity Continuous Exercise on Rate Pressure Product and Functional Capacity in Individuals With Increased BMI
- ClinicalTrials.gov ID
- NCT06584708
- Acronym / sponsor ID
- Rec/01817 Asma Rehman
- Conditions
- Overweight and Obesity
- Keywords
- Low volume High intensity training, Moderate Intensity Continous Exercise, Rate Pressure product, Functional capacity, Increased BMI
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 15 Feb 2024 (actual)
- Primary completion
- 1 Sep 2024 (actual)
- Study completion
- 1 Sep 2024 (actual)
- First posted
- 5 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To compare the effect of low volume high intensity training and moderate intensity continuous exercise on Rate Pressure Product (RPP) and functional capacity. Limited literature available on effectiveness of Low-volume HIIT in comparison of other Aerobic interventions in obese individuals. In our community, people are sedentary and not involved in routine exercise because of increased weight, so Low volume HIIT would be safe and convenient for such individuals to perform. There is also limited studies available on female gender so both genders are included in this study.
Detailed description
Some recent studies suggest that the rising interest for the potential of high- intensity interval training (HIIT) to enhance the metabolic health in overweight adults. HIIT has also been found to induce comparatively fast enhancements in overall-body aerobic capacity and muscle mitochondrial markers in individuals with overweight.
The main advantage of HIIT is that low-volume HIIT protocols can involve a shorter time as compared with MICT, and time limitations have been recognized as a generally reported hurdle to daily exercise involvement.
Latest studies propose that's when compared to moderate intensity continuous training (MICT), HIIT has been shown to produce similar and sometimes better improvements in results such as cardiorespiratory fitness in spite of often demanding a smaller amount of time commitment and lesser energy expenditure. On the other hand, low volume HIIT is still undecided whether this form of physical training is superior, equivalent or inferior to more outdated forms of exercise training such as MICT for the management cardio metabolic health.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Low-volume High intensity interval training | Experimental | Other: Low-volume high intensity interval trainingGroup A: Low-volume High intensity interval training |
| Moderate intensity continous exercise | Experimental | Other: Moderate intensity continuous exerciseGroup B: Moderate intensity continous exercise |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Body mass index 23-29.9 kg/m 2 (Overweight-Type I Obese)
- Able to do exercise (PAR-Q)
Key exclusion criteria (4 listed)
- History of chronic diseases and medication use
- Considerable mental or physical disability, neurological or musculoskeletal problems
- Severe personality disorders or drug addiction.
- Pregnant females
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Low-volume high intensity interval trainingWeek 1 \& 2: Warm-up: 10 minutes at 50% THR Work: 1x4 minutes at 80% THR followed by 1*4 minutes Recovery at 50% THR Cool down: 5 minutes at 50% THR Total exercise time: 23 minutes Week 3 \& 4: Warm-up: 10 minutes at 50% THR Work: 2x6 minutes at 80% THR followed by 1*6 minutes Recovery at 50% THR Cool down: 5 minutes at 50% THR Total exercise time: 33 minutes | Other | Low-volume High intensity interval training |
| Moderate intensity continuous exerciseWeek 1 \& 2: Warm-up: 5 minutes at 50% THR Work: 20 minutes at 60% VO 2 THR Cool Down: 5 minutes at 50% THR Total exercise time: 30 minutes Week 3 \& 4: Warm-up: 5 minutes at 50% THR Work: 30 minutes at 60% THR Cool Down: 5 minutes at 50% THR Total exercise time: 40 minutes | Other | Moderate intensity continous exercise |
Primary outcome
Rate Pressure Product
Time frame: 2 weeks, 4 weeks
Changes from baseline to 2 weeks and 4 weeks after the intervention, measured through product of heart rate and systolic blood pressure, is a very reliable indicator of myocardial oxygen demand. An RPP above 20,000 mmHg per minute is considered healthy, whereas anything below 16,000 mmHg is considered insufficient.
Functional Capacity
Time frame: 2 Weeks, 4 Weeks
Changes from baseline to 2 weeks and 4 weeks after the intervention, measured through 6 min walk test (6 MWT). It is a submaximal exercise test that can aid in assessing the functional/exercise capacity of patients with cardiopulmonary diseases, in this test we find out the maximum distance in meters that an individual covers in 6 min without any support.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Nov 2024.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Mehwish Waseem, MSPT-CPPT principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Low-volume high intensity interval training and Moderate intensity continuous exercise in people with Overweight and Obesity, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Nov 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Rate Pressure Product (time frame: 2 weeks, 4 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Nov 2024.