InfluenzaNCT06587984
Influenza Reminder Text-Messaging
A study testing Text message reminder in people with Influenza, run by Children's Hospital of Philadelphia at 1 site in United States.
Trial summary
Through a large, population-level quality improvement effort within the Children's Hospital of Philadelphia Care Network, we will evaluate text message reminders on flu vaccination rates for both patients with and without a scheduled well child care visit during flu season. Read more about this study
- Who is it for?
- Ages 6 months to 18 yearsHealthy volunteers can take part
- Conditions the study is for
- Influenza
- What is being tested?
- Text message reminder
- Type of treatment
- Vaccines, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 228,361 participants
- Where
- 1 siteUnited States
- Study dates
- 3 Sep 2024to 31 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 months to 18 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- All patients between ages 6 months-18 years old who have an upcoming well visit during the Fall of 2024 (September through December 2024) or had a completed well visit from January 2023 through August 2024
- Patients have a mobile phone number within their medical record
- Patients have opted-in to text communications from CHOP
- English-speaking
Who cannot join
- Subjects who do not meet the above inclusion criteria will be excluded
Trial locations and contacts
1 site in 1 country.
United States1 site
The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19146
About this study
Official title: Influenza Reminder Text-Messaging: A Randomized Quality Improvement Effort to Promote Influenza Vaccine in Pediatric Primary Care
Through a large, population-level quality improvement effort within the Children's Hospital of Philadelphia Care Network, we will evaluate text message reminders on flu vaccination rates for both patients with and without a scheduled well child care visit during flu season.
Read the detailed description
This is a randomized control trial with two patient cohorts: patients with and without a scheduled well child care visit during the upcoming 2024 flu season. Patients with a scheduled well child visit will be randomized into one of three groups (control, intervention message #1, or intervention message #2). Patients within the intervention groups will receive a one-time text message reminder to get their flu shot for their child at their child's upcoming well visit. Intervention groups will be texted at the same time, the same month as their child's well visit. The text message language will differ between groups. Patients without a scheduled upcoming well child visit during the 2024 flu season will also be randomized into one of three groups (control, intervention message #1, or intervention message #2). Intervention groups will be texted at the same time, at the start of flu season. The text message language will differ between groups.
Flu vaccine uptake will be measured within each patient cohort.
- Conditions
- Influenza
- Being tested
- Text message reminder
- Medical subject headings
- Influenza, Human
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Text message reminderBehavioural
One-time text message reminder with information about getting flu vaccine at CHOP
| Study group | Role | What they receive |
|---|---|---|
| Cohort 1a | No intervention | Patients within Cohort 1 have an upcoming well child visit between September-December 2024. Patients within Cohort 1a are those randomized to CONTROL and will not receive a text message reminder about getting their flu shot at their upcoming visit. |
| Cohort 1b | Experimental | Patients within Cohort 1 have an upcoming well child visit between September-December 2024. Patients within Cohort 1b are those randomized to INTERVENTION MESSAGE #1 and will receive text message reminder (variation #1) about getting their flu shot at their upcoming visit. Receives: Behavioral: Text message reminder |
| Cohort 1c | Experimental | Patients within Cohort 1 have an upcoming well child visit between September-December 2024. Patients within Cohort 1c are those randomized to INTERVENTION MESSAGE #2 and will receive text message reminder (variation #2) about getting their flu shot at their upcoming visit. Receives: Behavioral: Text message reminder |
| Cohort 2a | No intervention | Patients within Cohort 2 do not have an upcoming well visit between September-December 2024, but completed their well visit between January 2023 through August 2024. Patients within Cohort 2a are those randomized to CONTROL and will not receive a text message reminder about getting their flu shot. |
| Cohort 2b | Experimental | Patients within Cohort 2 do not have an upcoming well visit between September-December 2024, but completed their well visit between January 2023 through August 2024. Patients within Cohort 2b are those randomized to INTERVENTION MESSAGE #1 and will receive text message reminder (variation #3) about getting their flu shot this upcoming flu season. Receives: Behavioral: Text message reminder |
| Cohort 2c | Experimental | Patients within Cohort 2 do not have an upcoming well visit between September-December 2024, but completed their well visit between January 2023 through August 2024. Patients within Cohort 2b are those randomized to INTERVENTION MESSAGE #2 and will receive text message reminder (variation #4) about getting their flu shot this upcoming flu season. Receives: Behavioral: Text message reminder |
What is being measured
The primary outcome is the main question the study is designed to answer.
The effectiveness of a text message reminder on influenza vaccine uptake
Via prospective chart review, the primary outcome for both Cohort 1 and Cohort 2 will be to assess the number of patients who received an influenza vaccination 30 days post-text message reminder (baseline). Data from chart review will determine vaccination status (patient received influenza vaccination or not).
Measured: Baseline to approximately 30 days post-text message
Secondary outcomes (2)
The effectiveness of text message language within Cohort 1
Via prospective chart review, we will compare the number of patients within the Cohort 1 intervention groups who received influenza vaccination to understand which text message variation was more effective. Data from chart review will determine vaccination status (patient received influenza vaccination or not).
Measured: Baseline to approximately 30 days post-text message
The effectiveness of text message language within Cohort 2
Via prospective chart review, we will compare the number of patients within the Cohort 2 intervention groups who received influenza vaccination to understand which text message variation was more effective. Data from chart review will determine vaccination status (patient received influenza vaccination or not).
Measured: Baseline to approximately 30 days post-text message
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Sep 2024
- Study start3 Sep 2024
- Primary completion31 Dec 2024
- Study completion31 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for InfluenzaStudies of the same condition, open and under way.
- More trials run by Children's Hospital of PhiladelphiaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 228,361 participants (actual)
Sponsor and investigators
- Lead sponsor
- Children's Hospital of Philadelphia
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Brian P. Jenssen, MD, Principal investigator, Children's Hospital of Philadelphia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06587984
- Sponsor's protocol ID
- 24-022516
- Status last verified
- Sep 2025
- First submitted
- 5 Sep 2024
- Last updated
- 1 Oct 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 1 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influenza Reminder Text-Messaging: A Randomized Quality Improvement Effort to Promote Influenza Vaccine in Pediatric Primary Care
- ClinicalTrials.gov ID
- NCT06587984
- Acronym / sponsor ID
- 24-022516
- Conditions
- Influenza
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 228,361 participants (actual)
- Lead sponsor
- Children's Hospital of PhiladelphiaUniversity, hospital or other
- Study start
- 3 Sep 2024 (actual)
- Primary completion
- 31 Dec 2024 (actual)
- Study completion
- 31 Dec 2024 (actual)
- First posted
- 19 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Through a large, population-level quality improvement effort within the Children's Hospital of Philadelphia Care Network, we will evaluate text message reminders on flu vaccination rates for both patients with and without a scheduled well child care visit during flu season.
Detailed description
This is a randomized control trial with two patient cohorts: patients with and without a scheduled well child care visit during the upcoming 2024 flu season. Patients with a scheduled well child visit will be randomized into one of three groups (control, intervention message #1, or intervention message #2). Patients within the intervention groups will receive a one-time text message reminder to get their flu shot for their child at their child's upcoming well visit. Intervention groups will be texted at the same time, the same month as their child's well visit. The text message language will differ between groups. Patients without a scheduled upcoming well child visit during the 2024 flu season will also be randomized into one of three groups (control, intervention message #1, or intervention message #2). Intervention groups will be texted at the same time, at the start of flu season. The text message language will differ between groups.
Flu vaccine uptake will be measured within each patient cohort.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Single blind (participant)
- Number of arms
- 6
| Arm | Type | Receives |
|---|---|---|
| Cohort 1a | No intervention | –Patients within Cohort 1 have an upcoming well child visit between September-December 2024. Patients within Cohort 1a are those randomized to CONTROL and will not receive a text message reminder about getting their flu shot at their upcoming visit. |
| Cohort 1b | Experimental | Behavioral: Text message reminderPatients within Cohort 1 have an upcoming well child visit between September-December 2024. Patients within Cohort 1b are those randomized to INTERVENTION MESSAGE #1 and will receive text message reminder (variation #1) about getting their flu shot at their upcoming visit. |
| Cohort 1c | Experimental | Behavioral: Text message reminderPatients within Cohort 1 have an upcoming well child visit between September-December 2024. Patients within Cohort 1c are those randomized to INTERVENTION MESSAGE #2 and will receive text message reminder (variation #2) about getting their flu shot at their upcoming visit. |
| Cohort 2a | No intervention | –Patients within Cohort 2 do not have an upcoming well visit between September-December 2024, but completed their well visit between January 2023 through August 2024. Patients within Cohort 2a are those randomized to CONTROL and will not receive a text message reminder about getting their flu shot. |
| Cohort 2b | Experimental | Behavioral: Text message reminderPatients within Cohort 2 do not have an upcoming well visit between September-December 2024, but completed their well visit between January 2023 through August 2024. Patients within Cohort 2b are those randomized to INTERVENTION MESSAGE #1 and will receive text message reminder (variation #3) about getting their flu shot this upcoming flu season. |
| Cohort 2c | Experimental | Behavioral: Text message reminderPatients within Cohort 2 do not have an upcoming well visit between September-December 2024, but completed their well visit between January 2023 through August 2024. Patients within Cohort 2b are those randomized to INTERVENTION MESSAGE #2 and will receive text message reminder (variation #4) about getting their flu shot this upcoming flu season. |
Who may qualify
- Ages
- 6 months to 18 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (4 listed)
- All patients between ages 6 months-18 years old who have an upcoming well visit during the Fall of 2024 (September through December 2024) or had a completed well visit from January 2023 through August 2024
- Patients have a mobile phone number within their medical record
- Patients have opted-in to text communications from CHOP
- English-speaking
Key exclusion criteria (1 listed)
- Subjects who do not meet the above inclusion criteria will be excluded
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Text message reminderOne-time text message reminder with information about getting flu vaccine at CHOP | Behavioural | Cohort 1b, Cohort 1c, Cohort 2b, Cohort 2c |
Primary outcome
The effectiveness of a text message reminder on influenza vaccine uptake
Time frame: Baseline to approximately 30 days post-text message
Via prospective chart review, the primary outcome for both Cohort 1 and Cohort 2 will be to assess the number of patients who received an influenza vaccination 30 days post-text message reminder (baseline). Data from chart review will determine vaccination status (patient received influenza vaccination or not).
2 secondary outcomes
The effectiveness of text message language within Cohort 1
Time frame: Baseline to approximately 30 days post-text message
The effectiveness of text message language within Cohort 2
Time frame: Baseline to approximately 30 days post-text message
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Oct 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Brian P. Jenssen, MD principal investigator
Children's Hospital of Philadelphia
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Text message reminder in people with Influenza, run by Children's Hospital of Philadelphia at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 1 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The effectiveness of a text message reminder on influenza vaccine uptake (time frame: Baseline to approximately 30 days post-text message). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Oct 2025.