Life ExperiencesNUS1000SENCT06594549
Sleep Health, Workplace Stress and Wellbeing in NUS Staff: the NUS1000 Staff Edition Study
An observational study of Life Experiences, run by National University of Singapore at 1 site in Singapore.
Trial summary
Workplace stress can significantly affect workers sleep, physical health and mental wellbeing. Recognizing and characterizing obstacles to healthy sleep patterns in office workers can help identify targets for corporate interventions that improve productivity and workplace wellbeing. Read more about this study
- Who is it for?
- Ages 35 to 70 yearsHealthy volunteers can take part
- Conditions the study is for
- Life Experiences
- How many people
- 575 participants
- Where
- 1 siteSingapore
- Study dates
- 1 Nov 2024to 1 Mar 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 to 70 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: 1000 National University of Singapore staff
Who may be able to join
- NUS staff between the age of 35-70 with smartphones operating on Android 8.0 and up, or iOS 14.0 or later
Who cannot join
- Participants will be required to :
- Have their sleep and physical activity rhythms recorded via wearable sensors, while they continue daily life as usual.
- Complete periodic questionnaires and short daily surveys on their smartphones.
- Agree to interactions with their smartphones and NUS e-services (e.g., email) tracked.
- Participants who do not agree to have these measures recorded will not be eligible for the study. Shift workers (e.g., security personnel, doctors and nurses), nursing/pregnant woman, and patients with existing sleep/psychological disorders (e.g., insomnia and major depression) will also be excluded.
Trial locations and contacts
1 site in 1 country.
Singapore1 site
Yong Loo Lin School of Medicine
Singapore, Singapore, 117549
About this study
Workplace stress can significantly affect workers sleep, physical health and mental wellbeing. Recognizing and characterizing obstacles to healthy sleep patterns in office workers can help identify targets for corporate interventions that improve productivity and workplace wellbeing. Following the investigator\'s experience with the NUS1000 study in 1st year students conducted in Aug-Dec 2023, the investigators will now track daily sleep, wellbeing and time-use in NUS staff for 1 year in the present study. These data will reveal work-related stressors that impact daily sleep and mood. In addition, the investigators will investigate whether daily sleep and stress are associated with cardiovascular health in this middle-age cohort.
Read the detailed description
The investigators aim to answer the following questions using a combination of objective sleep tracking (Oura ring), smartphone-based questionnaires (EMA), passive tracking of interactions on smartphones (Quantactions) and one-time arterial stiffness measures (SphygmoCor).
- Identify obstacles to healthy sleep patterns in NUS staff 1.1) How do staff sleep, in terms of duration, timing, regularity and napping behaviour? 1.2) What is the gulf between sleep aspiration and attained sleep? 1.3) What are self-perceived obstacles to achieving better sleep? 1.4) What activities potentially displace time for sleep?
- Understand inter-relationships between sleep, workplace stressors and wellbeing outcomes 2.1) How is sleep is modulated over the year? 2.2) How do work patterns (e.g., after-hours/vacation emails) correlate with sleep, physical activity, subjective wellbeing, physiological markers of stress? 2.3) How do work, social, status stress and other life events contribute to sleep, wellbeing and subjective perceptions of work productivity?
- Examine the association between sleep, workplace stress, mental health, cardiovascular risks in middle-aged cohort 3.1) How do daily sleep, work place events and acute/chronic stress contribute to cardiovascular health atmiddle age? 3.2) How is subjective wellbeing associated with objective cardiovascular wellbeing?
- Examine the effects of any structural organizational efforts to promote wellbeing on staff sleep and stress
The investigators hypothesize that acute stressors, such as receiving emails after office hours and during vacation periods, will negatively impact sleep duration and regularity, as well as subjective stress rating over a short period. Chronic stressors, such as family care burden and pressure from supervisor, will be associated with longer-term insufficient and irregular sleep. Staff members reporting high chronic stress and frequent acute stress may be more likely to have high cardiovascular and cerebrovascular risks. In general, irregular/short sleep, constant high subjective stress, and frequent routine disruption (i.e., after hours work) will be associated with high cardiovascular risk in middle-aged participants.
- Conditions
- Life Experiences
- Keywords
- Employee, Sleep, Wellbeing, Stress, Cardiovascular, Workplace
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Staff | NUS Staff |
What is being measured
The primary outcome is the main question the study is designed to answer.
Time-use diary
Participants will be asked to fill out a time-use diary over 2-week periods every 3 months throughout the follow-up period (Month 1, Month 3, Month 6, Month 9 and Month 12), indicating the activities they engaged in over the past day on the smartphone app.
Measured: Across the 1 year study
Blood Pressure
Blood pressure measures will be taken twice via an Omron blood pressure device.
Measured: Across the 1 year study
Arterial Stiffness
Arterial stiffness will be assessed by SphygmoCor XCEL system (cuff plus tonometer) and pulse wave velocity will be derived.
Measured: Across the 1 year study
Height
Height will be measured by the device linked to the body composition system (cm).
Measured: Across the 1 year study
Weight
Weight will be measured by the device linked to the body composition system (in kg).
Measured: Across the 1 year study
Body composition
Body composition will be assessed by InBody 770 Bioelectrical Impedance Analysis machine.
Measured: Across the 1 year study
Smartphone Touchscreen Interactions
Smartphone taps (number) will be tracked automatically through an EU-GDPR (the European Union's stringent privacy regulation) compliant smartphone app (QuantActions). This application logs human-smartphone screen interactions (e.g., taps, swipes) during regular use by logging a location-specific timestamp for each screen contact, and the name of the active app at that moment. This gives us a readout of phone use, app use, and an implicit measure of alertness (tapping speed). Only timestamps of touchscreen interactions and the associated apps will be recorded. No text, pictures, contacts, or any person identifying information will be collected. Moreover, data will be gathered and stored on the cloud using codes only; names or emails will not be collected.
Measured: Across the 1 year study
Sleep time
The Oura ring is a device worn on the finger which non-invasively records movement, heart rate and temperature to infer sleep and physical activity. Sleep Onset Time, Wake Time, on Workday (weekday) and Free Day (Weekend / vacation) will be recorded for nocturnal sleep and naps.
Measured: Across the 1 year study
Sleep duration
The Oura ring is a device worn on the finger which non-invasively records movement, heart rate and temperature to infer sleep and physical activity. Sleep Duration on Workday (weekday) and Free Day (Weekend / vacation) will be recorded for nocturnal sleep and naps.
Measured: Across the 1 year study
Wake after sleep onset
The Oura ring is a device worn on the finger which non-invasively records movement, heart rate and temperature to infer sleep and physical activity. Wake after Sleep Onset on Workday (weekday) and Free Day (Weekend / vacation) will be recorded.
Measured: Across the 1 year study
Sleep regularity
The Oura ring is a device worn on the finger which non-invasively records movement, heart rate and temperature to infer sleep and physical activity. Sleep Regularity (computed via Std Deviation and Sleep Regularity Index; evaluated over 4 weeks minimally) will be recorded.
Measured: Across the 1 year study
Well-being
Participants input ratings about a rotating set of questions concerning wellbeing daily through a smartphone based app (Z4IP) that has been used in prior studies. This daily assessment can be done anytime between 8pm and 12am each day. Higher scores represent higher levels of well-being.
Measured: Across the 1 year study
Self-reported health
Participants will also be required to complete a subset of health questionnaires every 3 months throughout the follow-up period (Month 1, Month 3,Month 6, Month 9 and Month 12) on the Qualtrics survey platform.
Measured: Across the 1 year study
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Sep 2024
- Study start1 Nov 2024
- Primary completion1 Feb 2026
- Study completion1 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Life ExperiencesStudies of the same condition, open and under way.
- More trials run by National University of SingaporeThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 575 participants (actual)
Sponsor and investigators
- Lead sponsor
- National University of Singapore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Michael W.L. Chee, National University of Singapore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06594549
- Sponsor's protocol ID
- NUS1000 staff edition
- Acronym
- NUS1000SE
- Status last verified
- Oct 2026
- First submitted
- 3 Sep 2024
- Last updated
- 8 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Soon CS, Chua XY, Qin S, Ong JL, Massar SAA, Willoughby A, Chong KHM, Chee MWL. Personalized definition of short sleep using long-term wearable sleep distributions. Sleep Med. 2026 Sep 30;149:109294. doi: 10.1016/j.sleep.2026.109294. Online ahead of print.
PubMed 42833133
Study at a glance
From the registry record, last updated by the sponsor on 8 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Sleep Health, Workplace Stress and Wellbeing in NUS Staff: the NUS1000 Staff Edition Study
- ClinicalTrials.gov ID
- NCT06594549
- Acronym / sponsor ID
- NUS1000SE / NUS1000 staff edition
- Conditions
- Life Experiences
- Keywords
- Employee, Sleep, Wellbeing, Stress, Cardiovascular, Workplace
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 575 participants (actual)
- Lead sponsor
- National University of SingaporeUniversity, hospital or other
- Study start
- 1 Nov 2024 (actual)
- Primary completion
- 1 Feb 2026 (actual)
- Study completion
- 1 Mar 2026 (actual)
- First posted
- 19 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Workplace stress can significantly affect workers sleep, physical health and mental wellbeing. Recognizing and characterizing obstacles to healthy sleep patterns in office workers can help identify targets for corporate interventions that improve productivity and workplace wellbeing. Following the investigator\'s experience with the NUS1000 study in 1st year students conducted in Aug-Dec 2023, the investigators will now track daily sleep, wellbeing and time-use in NUS staff for 1 year in the present study. These data will reveal work-related stressors that impact daily sleep and mood. In addition, the investigators will investigate whether daily sleep and stress are associated with cardiovascular health in this middle-age cohort.
Detailed description
The investigators aim to answer the following questions using a combination of objective sleep tracking (Oura ring), smartphone-based questionnaires (EMA), passive tracking of interactions on smartphones (Quantactions) and one-time arterial stiffness measures (SphygmoCor).
- Identify obstacles to healthy sleep patterns in NUS staff 1.1) How do staff sleep, in terms of duration, timing, regularity and napping behaviour? 1.2) What is the gulf between sleep aspiration and attained sleep? 1.3) What are self-perceived obstacles to achieving better sleep? 1.4) What activities potentially displace time for sleep?
- Understand inter-relationships between sleep, workplace stressors and wellbeing outcomes 2.1) How is sleep is modulated over the year? 2.2) How do work patterns (e.g., after-hours/vacation emails) correlate with sleep, physical activity, subjective wellbeing, physiological markers of stress? 2.3) How do work, social, status stress and other life events contribute to sleep, wellbeing and subjective perceptions of work productivity?
- Examine the association between sleep, workplace stress, mental health, cardiovascular risks in middle-aged cohort 3.1) How do daily sleep, work place events and acute/chronic stress contribute to cardiovascular health atmiddle age? 3.2) How is subjective wellbeing associated with objective cardiovascular wellbeing?
- Examine the effects of any structural organizational efforts to promote wellbeing on staff sleep and stress
The investigators hypothesize that acute stressors, such as receiving emails after office hours and during vacation periods, will negatively impact sleep duration and regularity, as well as subjective stress rating over a short period. Chronic stressors, such as family care burden and pressure from supervisor, will be associated with longer-term insufficient and irregular sleep. Staff members reporting high chronic stress and frequent acute stress may be more likely to have high cardiovascular and cerebrovascular risks. In general, irregular/short sleep, constant high subjective stress, and frequent routine disruption (i.e., after hours work) will be associated with high cardiovascular risk in middle-aged participants.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Staff | – | –NUS Staff |
Who may qualify
- Ages
- 35 to 70 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- 1000 National University of Singapore staff
Key inclusion criteria (1 listed)
- NUS staff between the age of 35-70 with smartphones operating on Android 8.0 and up, or iOS 14.0 or later
Key exclusion criteria (5 listed)
- Have their sleep and physical activity rhythms recorded via wearable sensors, while they continue daily life as usual.
- Complete periodic questionnaires and short daily surveys on their smartphones.
- Agree to interactions with their smartphones and NUS e-services (e.g., email) tracked.
- Participants who do not agree to have these measures recorded will not be eligible for the study. Shift workers (e.g., security personnel, doctors and nurses), nursing/pregnant woman, and patients with existing sleep/psychological disorders (e.g., insomnia and major depression) will also be excluded.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Time-use diary
Time frame: Across the 1 year study
Participants will be asked to fill out a time-use diary over 2-week periods every 3 months throughout the follow-up period (Month 1, Month 3, Month 6, Month 9 and Month 12), indicating the activities they engaged in over the past day on the smartphone app.
Blood Pressure
Time frame: Across the 1 year study
Blood pressure measures will be taken twice via an Omron blood pressure device.
Arterial Stiffness
Time frame: Across the 1 year study
Arterial stiffness will be assessed by SphygmoCor XCEL system (cuff plus tonometer) and pulse wave velocity will be derived.
Height
Time frame: Across the 1 year study
Height will be measured by the device linked to the body composition system (cm).
Weight
Time frame: Across the 1 year study
Weight will be measured by the device linked to the body composition system (in kg).
Body composition
Time frame: Across the 1 year study
Body composition will be assessed by InBody 770 Bioelectrical Impedance Analysis machine.
Smartphone Touchscreen Interactions
Time frame: Across the 1 year study
Smartphone taps (number) will be tracked automatically through an EU-GDPR (the European Union's stringent privacy regulation) compliant smartphone app (QuantActions). This application logs human-smartphone screen interactions (e.g., taps, swipes) during regular use by logging a location-specific timestamp for each screen contact, and the name of the active app at that moment. This gives us a readout of phone use, app use, and an implicit measure of alertness (tapping speed). Only timestamps of touchscreen interactions and the associated apps will be recorded. No text, pictures, contacts, or any person identifying information will be collected. Moreover, data will be gathered and stored on the cloud using codes only; names or emails will not be collected.
Sleep time
Time frame: Across the 1 year study
The Oura ring is a device worn on the finger which non-invasively records movement, heart rate and temperature to infer sleep and physical activity. Sleep Onset Time, Wake Time, on Workday (weekday) and Free Day (Weekend / vacation) will be recorded for nocturnal sleep and naps.
Sleep duration
Time frame: Across the 1 year study
The Oura ring is a device worn on the finger which non-invasively records movement, heart rate and temperature to infer sleep and physical activity. Sleep Duration on Workday (weekday) and Free Day (Weekend / vacation) will be recorded for nocturnal sleep and naps.
Wake after sleep onset
Time frame: Across the 1 year study
The Oura ring is a device worn on the finger which non-invasively records movement, heart rate and temperature to infer sleep and physical activity. Wake after Sleep Onset on Workday (weekday) and Free Day (Weekend / vacation) will be recorded.
Sleep regularity
Time frame: Across the 1 year study
The Oura ring is a device worn on the finger which non-invasively records movement, heart rate and temperature to infer sleep and physical activity. Sleep Regularity (computed via Std Deviation and Sleep Regularity Index; evaluated over 4 weeks minimally) will be recorded.
Well-being
Time frame: Across the 1 year study
Participants input ratings about a rotating set of questions concerning wellbeing daily through a smartphone based app (Z4IP) that has been used in prior studies. This daily assessment can be done anytime between 8pm and 12am each day. Higher scores represent higher levels of well-being.
Self-reported health
Time frame: Across the 1 year study
Participants will also be required to complete a subset of health questionnaires every 3 months throughout the follow-up period (Month 1, Month 3,Month 6, Month 9 and Month 12) on the Qualtrics survey platform.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Oct 2026.
- Derived from this study: PubMed 42833133Soon CS, Chua XY, Qin S, Ong JL, Massar SAA, Willoughby A, Chong KHM, Chee MWL. Personalized definition of short sleep using long-term wearable sleep distributions. Sleep Med. 2026 Sep 30;149:109294. doi: 10.1016/j.sleep.2026.109294. Online ahead of print.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Life Experiences, run by National University of Singapore at 1 site in Singapore.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Singapore. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Time-use diary (time frame: Across the 1 year study). The study lists 13 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06594549, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Oct 2026.