Sickle Cell AnaemiaNCT06601894
The Relationship of Platelet Counts With Sickle Cell Anemia in the Eastern Region of Saudi Arabia
An observational study of Sickle Cell Anaemia and SCD, run by Majmaah University at 1 site in Saudi Arabia.
Trial summary
This study aims to evaluate the relationship between platelet counts and sickle cell disease in the eastern region of the Kingdom of Saudi Arabia. Read more about this study
- Who is it for?
- Ages 1 year and older
- Conditions the study is for
- Sickle Cell Anaemia, SCD
- What is being tested?
- Platelets count
- How many people
- 650 participants
- Where
- 1 siteSaudi Arabia
- Study dates
- 1 Dec 2024to 30 Mar 2025
- How long will I take part?
- 1 Month
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 1 year and older
- All sexes
- Child, Adult, Older adult
Study population: The study will include a cohort of people with SCD who are registered at the Hereditary Blood center al-ahssa.
Inclusion criteria: All the diagnosed patients of sickle cell disease regardless of age and gender.
Exclusion criteria: Patients without having sickle cell disease regardless of age and gender.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Saudi Arabia1 site
Khalid Ali Majrashi
Dammam
MOHAMMED A Eidaroos, PHD, 0164042900, m.alaidarous@mu.edu.sa
KHALID A MAJRASHI
About this study
This study aims to evaluate the relationship between platelet counts and sickle cell disease in the eastern region of the Kingdom of Saudi Arabia.
Read the detailed description
Introduction:
This study aims to evaluate the relationship between platelet counts and sickle cell disease in the eastern region of the Kingdom of Saudi Arabia.
Purpose: This study aims to assess the prevalence and factors associated with elevated platelet counts in people with sickle cell disease in the eastern region of Saudi Arabia.
Methods: This cross-sectional study at Majmaah University will analyze prerecorded data frfom the eastern region of Saudi Arabia to investigate the relationship between platelet counts and sickle cell disease, identifying associated factors and assessing the link .
Importance: To assess the relationship between platelet counts and disease severity in Pationt with SCD.
Aim :To investigate the relationship between platelet counts and SCD in the eastern region of the Kingdom of Saudi Arabia.
- Conditions
- Sickle Cell Anaemia, SCD
- Being tested
- Platelets count
- Medical subject headings
- Anemia, Sickle Cell
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Platelets countDiagnostic test
the study include will take medical investigation data for all sickle cell patients.
| Study group | Role | What they receive |
|---|---|---|
| Males | The study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia. Receives: Diagnostic Test: Platelets count | |
| Children | The study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia. Receives: Diagnostic Test: Platelets count | |
| Females | The study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia. Receives: Diagnostic Test: Platelets count |
What is being measured
The primary outcome is the main question the study is designed to answer.
Collecting platelet data for sickle cell anemia patients
Collecting platelet data for sickle cell anemia patients in males and female and children based on different ages, then analyzing them and studying their relationship
Measured: From January 2023 to December 2023
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Sep 2024
- Study start1 Dec 2024 (estimated)
- Primary completion31 Dec 2024 (estimated)
- Study completion30 Mar 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Sickle Cell AnaemiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 650 participants (estimated)
- Target duration
- 1 Month
Sponsor and investigators
- Lead sponsor
- Majmaah University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Khalid Ali Majrashi, Majmaah University
- Investigators
- Khalid A Majrashi, Principal investigator, Majmaah University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06601894
- Sponsor's protocol ID
- IRB Log No.: 29-EP-2024
- Status last verified
- Oct 2024
- First submitted
- 16 Sep 2024
- Last updated
- 4 Oct 2024
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
- Individual data sharing
- Undecided
Publications
Wun T, Paglieroni T, Rangaswami A, Franklin PH, Welborn J, Cheung A, Tablin F. Platelet activation in patients with sickle cell disease. Br J Haematol. 1998 Mar;100(4):741-9. doi: 10.1046/j.1365-2141.1998.00627.x.
PubMed 9531343Shome DK, Jaradat A, Mahozi AI, Sinan AS, Ebrahim A, Alrahim M, Ebraheem MS, Mansoor EJ, Majed KS, Azeez Pasha SA. The Platelet Count and its Implications in Sickle Cell Disease Patients Admitted for Intensive Care. Indian J Crit Care Med. 2018 Aug;22(8):585-590. doi: 10.4103/ijccm.IJCCM_49_18.
PubMed 30186009Yee MEM, Batsuli G, Chonat S, Park S. Thrombocytosis with acquired von Willebrand disease in an adolescent with sickle cell disease. Clin Case Rep. 2020 Nov 20;9(1):457-460. doi: 10.1002/ccr3.3556. eCollection 2021 Jan.
PubMed 33489197
Study at a glance
From the registry record, last updated by the sponsor on 4 Oct 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Relationship of Platelet Counts With Sickle Cell Anemia in the Eastern Region of Saudi Arabia
- ClinicalTrials.gov ID
- NCT06601894
- Acronym / sponsor ID
- IRB Log No.: 29-EP-2024
- Conditions
- Sickle Cell Anaemia, SCD
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 650 participants (estimated)
- Lead sponsor
- Majmaah UniversityUniversity, hospital or other
- Study start
- 1 Dec 2024 (estimated)
- Primary completion
- 31 Dec 2024 (estimated)
- Study completion
- 30 Mar 2025 (estimated)
- First posted
- 19 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the relationship between platelet counts and sickle cell disease in the eastern region of the Kingdom of Saudi Arabia.
Detailed description
Introduction:
This study aims to evaluate the relationship between platelet counts and sickle cell disease in the eastern region of the Kingdom of Saudi Arabia.
Purpose: This study aims to assess the prevalence and factors associated with elevated platelet counts in people with sickle cell disease in the eastern region of Saudi Arabia.
Methods: This cross-sectional study at Majmaah University will analyze prerecorded data frfom the eastern region of Saudi Arabia to investigate the relationship between platelet counts and sickle cell disease, identifying associated factors and assessing the link .
Importance: To assess the relationship between platelet counts and disease severity in Pationt with SCD.
Aim :To investigate the relationship between platelet counts and SCD in the eastern region of the Kingdom of Saudi Arabia.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Month
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Males | – | Diagnostic Test: Platelets countThe study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia. |
| Children | – | Diagnostic Test: Platelets countThe study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia. |
| Females | – | Diagnostic Test: Platelets countThe study will be conducted on CBC count special PLT for adult Males of different ages with sickle cell anemia. |
Who may qualify
- Ages
- 1 year and older
- Sex
- All
- Age groups
- Child, Adult, Older adult
- Study population
- The study will include a cohort of people with SCD who are registered at the Hereditary Blood center al-ahssa.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Platelets countthe study include will take medical investigation data for all sickle cell patients. | Diagnostic test | Children, Females, Males |
Primary outcome
Collecting platelet data for sickle cell anemia patients
Time frame: From January 2023 to December 2023
Collecting platelet data for sickle cell anemia patients in males and female and children based on different ages, then analyzing them and studying their relationship
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Oct 2024.
- Results publication: PubMed 9531343Wun T, Paglieroni T, Rangaswami A, Franklin PH, Welborn J, Cheung A, Tablin F. Platelet activation in patients with sickle cell disease. Br J Haematol. 1998 Mar;100(4):741-9. doi: 10.1046/j.1365-2141.1998.00627.x.
- Results publication: PubMed 30186009Shome DK, Jaradat A, Mahozi AI, Sinan AS, Ebrahim A, Alrahim M, Ebraheem MS, Mansoor EJ, Majed KS, Azeez Pasha SA. The Platelet Count and its Implications in Sickle Cell Disease Patients Admitted for Intensive Care. Indian J Crit Care Med. 2018 Aug;22(8):585-590. doi: 10.4103/ijccm.IJCCM_49_18.
- Results publication: PubMed 33489197Yee MEM, Batsuli G, Chonat S, Park S. Thrombocytosis with acquired von Willebrand disease in an adolescent with sickle cell disease. Clin Case Rep. 2020 Nov 20;9(1):457-460. doi: 10.1002/ccr3.3556. eCollection 2021 Jan.
- Individual participant dataSharing planned: Undecided
Related trials for Sickle Cell Anaemia
Not yet recruiting
Hypoxic Red Blood Cells in Sickle Cell Anemia
Sickle Cell Anaemia, Sickle Cell Anemia Crisis
RecruitingPhase 2
Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype
Sickle Cell Disease, Sickle Cell Anaemia
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Khalid A Majrashi principal investigator
Majmaah University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Sickle Cell Anaemia and SCD, run by Majmaah University at 1 site in Saudi Arabia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 4 Oct 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Saudi Arabia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Khalid A Majrashi (0533489978, khalid77555@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Collecting platelet data for sickle cell anemia patients (time frame: From January 2023 to December 2023). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06601894, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Oct 2024; AzTrials last refreshed its copy on 7 Nov 2026.